Emili Salo

Summary

Affiliation: Universitat de Barcelona
Country: Spain

Publications

  1. doi request reprint Planarian regeneration: achievements and future directions after 20 years of research
    Emili Salo
    Departament de Genetica, Facultat de Biologia and Institut de Biomedicina de la Universitat de Barcelona IBUB, Barcelona, Catalunya, Spain
    Int J Dev Biol 53:1317-27. 2009
  2. ncbi request reprint The power of regeneration and the stem-cell kingdom: freshwater planarians (Platyhelminthes)
    Emili Salo
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain
    Bioessays 28:546-59. 2006
  3. doi request reprint Silencing of Smed-betacatenin1 generates radial-like hypercephalized planarians
    Marta Iglesias
    Departament de Genetica, Universitat de Barcelona, 08028 Barcelona, Spain
    Development 135:1215-21. 2008
  4. doi request reprint Noggin and noggin-like genes control dorsoventral axis regeneration in planarians
    M Dolores Molina
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona and Institut de Biomedicina de Universitat de Barcelona, Avinguda Diagonal 645, Edifici annex, Planta 1, 08028 Barcelona, Catalunya, Spain
    Curr Biol 21:300-5. 2011
  5. doi request reprint Expression pattern of the expanded noggin gene family in the planarian Schmidtea mediterranea
    M Dolores Molina
    Departament de Genetica, Facultat de Biologia and Institut de Biomedicina de la Universitat de Barcelona IBUB, Av Diagonal 645, Edifici annex, Planta 1, 08028 Barcelona, Catalunya, Spain
    Gene Expr Patterns 9:246-53. 2009
  6. doi request reprint Early planarian brain regeneration is independent of blastema polarity mediated by the Wnt/β-catenin pathway
    Marta Iglesias
    Department of Genetics and Institute of Biomedicine, University of Barcelona, Av Diagonal 645, E 08028 Barcelona, Catalonia, Spain
    Dev Biol 358:68-78. 2011
  7. pmc Dishevelled is essential for neural connectivity and planar cell polarity in planarians
    Maria Almuedo-Castillo
    Department of Genetics and Institute of Biomedicine, University of Barcelona, E 08028 Barcelona, Catalonia, Spain
    Proc Natl Acad Sci U S A 108:2813-8. 2011
  8. ncbi request reprint Gtwnt-5 a member of the wnt family expressed in a subpopulation of the nervous system of the planarian Girardia tigrina
    Maria Marsal
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain
    Gene Expr Patterns 3:489-95. 2003
  9. pmc Smed454 dataset: unravelling the transcriptome of Schmidtea mediterranea
    Josep F Abril
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona UB, Barcelona, Catalunya, Spain
    BMC Genomics 11:731. 2010
  10. pmc Gradients in planarian regeneration and homeostasis
    Teresa Adell
    Department of Genetics and Institute of Biomedicine, University of Barcelona, Av Diagonal 645, E 08028 Barcelona, Catalonia, Spain
    Cold Spring Harb Perspect Biol 2:a000505. 2010

Collaborators

Detail Information

Publications25

  1. doi request reprint Planarian regeneration: achievements and future directions after 20 years of research
    Emili Salo
    Departament de Genetica, Facultat de Biologia and Institut de Biomedicina de la Universitat de Barcelona IBUB, Barcelona, Catalunya, Spain
    Int J Dev Biol 53:1317-27. 2009
    ..In this review, we provide an overview of planarians as a model system for research into development and regeneration and describe new lines of investigation in this area...
  2. ncbi request reprint The power of regeneration and the stem-cell kingdom: freshwater planarians (Platyhelminthes)
    Emili Salo
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain
    Bioessays 28:546-59. 2006
    ..Such information should also pave the way to understanding the genetic pathways associated with metazoan somatic stem-cell regulation and pattern formation...
  3. doi request reprint Silencing of Smed-betacatenin1 generates radial-like hypercephalized planarians
    Marta Iglesias
    Departament de Genetica, Universitat de Barcelona, 08028 Barcelona, Spain
    Development 135:1215-21. 2008
    ..mediterranea beta-catenins could be functionally specialized and that only Smed-betacatenin1 is involved in Wnt signalling...
  4. doi request reprint Noggin and noggin-like genes control dorsoventral axis regeneration in planarians
    M Dolores Molina
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona and Institut de Biomedicina de Universitat de Barcelona, Avinguda Diagonal 645, Edifici annex, Planta 1, 08028 Barcelona, Catalunya, Spain
    Curr Biol 21:300-5. 2011
    ..Remarkably, this ventralization is not associated with an increase in SMAD1/5/8 phosphorylation...
  5. doi request reprint Expression pattern of the expanded noggin gene family in the planarian Schmidtea mediterranea
    M Dolores Molina
    Departament de Genetica, Facultat de Biologia and Institut de Biomedicina de la Universitat de Barcelona IBUB, Av Diagonal 645, Edifici annex, Planta 1, 08028 Barcelona, Catalunya, Spain
    Gene Expr Patterns 9:246-53. 2009
    ..In situ hybridizations show that planarian noggin genes are expressed in a variety of cell types located in different regions of the planarian body...
  6. doi request reprint Early planarian brain regeneration is independent of blastema polarity mediated by the Wnt/β-catenin pathway
    Marta Iglesias
    Department of Genetics and Institute of Biomedicine, University of Barcelona, Av Diagonal 645, E 08028 Barcelona, Catalonia, Spain
    Dev Biol 358:68-78. 2011
    ....
  7. pmc Dishevelled is essential for neural connectivity and planar cell polarity in planarians
    Maria Almuedo-Castillo
    Department of Genetics and Institute of Biomedicine, University of Barcelona, E 08028 Barcelona, Catalonia, Spain
    Proc Natl Acad Sci U S A 108:2813-8. 2011
    ..These data represent evidence not only of the function of the PCP network in lophotrocozoans but of the involvement of the PCP core elements Vang and Div in apical positioning of the cilia...
  8. ncbi request reprint Gtwnt-5 a member of the wnt family expressed in a subpopulation of the nervous system of the planarian Girardia tigrina
    Maria Marsal
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain
    Gene Expr Patterns 3:489-95. 2003
    ..All these data provide us with a new neural marker for the planarian brain, and can be used to follow regeneration of the CNS...
  9. pmc Smed454 dataset: unravelling the transcriptome of Schmidtea mediterranea
    Josep F Abril
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona UB, Barcelona, Catalunya, Spain
    BMC Genomics 11:731. 2010
    ..However, a detailed description of the planarian transcriptome is essential for future investigation into regenerative processes using planarians as a model system...
  10. pmc Gradients in planarian regeneration and homeostasis
    Teresa Adell
    Department of Genetics and Institute of Biomedicine, University of Barcelona, Av Diagonal 645, E 08028 Barcelona, Catalonia, Spain
    Cold Spring Harb Perspect Biol 2:a000505. 2010
    ..Here, we discuss whether the actions of these molecules could be based on morphogenetic gradients...
  11. doi request reprint Smed-SmB, a member of the LSm protein superfamily, is essential for chromatoid body organization and planarian stem cell proliferation
    Enrique Fernández-Taboada
    University of Barcelona, Department of Genetics, IBUB, Av Diagonal 645, 08028, Barcelona, Spain
    Development 137:1055-65. 2010
    ..In summary, our results suggest that Smed-SmB is an essential component of the chromatoid body, crucial to ensure a proper RNA metabolism and essential for stem cell proliferation...
  12. ncbi request reprint Planarian Gtsix3, a member of the Six/so gene family, is expressed in brain branches but not in eye cells
    David Pineda
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, E 08071 Barcelona, Spain
    Gene Expr Patterns 2:169-73. 2002
    ..These findings provide a new marker for the developing anterior nervous system and evidence the complexity of planarian brain...
  13. doi request reprint Inhibitory Smads and bone morphogenetic protein (BMP) modulate anterior photoreceptor cell number during planarian eye regeneration
    Alejandro González-Sastre
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Barcelona, Catalunya, Spain
    Int J Dev Biol 56:155-63. 2012
    ..Our results suggest that Smed-smad6/7-2 and Smed-bmp control the re-specification and maintenance of anterior photoreceptor cell number in S. mediterranea...
  14. ncbi request reprint Genetic network of the eye in Platyhelminthes: expression and functional analysis of some players during planarian regeneration
    Emili Salo
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, E 08071 Barcelona, Spain
    Gene 287:67-74. 2002
    ..We describe the effects of RNA interference-mediated loss of function on eye regeneration. Finally, we discuss the relevance of these findings for the evolution of the eye gene network...
  15. pmc A proteomics approach to decipher the molecular nature of planarian stem cells
    Enrique Fernández-Taboada
    Departament de Genètica and Institute of Biomedicine, Universitat de Barcelona, Avenida Diagonal 645, Barcelona, Catalonia, Spain
    BMC Genomics 12:133. 2011
    ..Sequencing of the Schmidtea mediterranea genome and some expressed sequence tag projects have generated extensive data on the genetic profile of these cells. However, little information is available on their protein dynamics...
  16. ncbi request reprint The planarian nanos-like gene Smednos is expressed in germline and eye precursor cells during development and regeneration
    Mette Handberg-Thorsager
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain
    Dev Genes Evol 217:403-11. 2007
    ..Our results suggest that similar genetic mechanisms might be used to control the differentiation of precursor cells during development and regeneration in planarians...
  17. doi request reprint Planarian GSK3s are involved in neural regeneration
    Teresa Adell
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028, Barcelona, Spain
    Dev Genes Evol 218:89-103. 2008
    ..This phenotype is consistent with a role for Smed-GSK3s in neuronal polarization and axonal growth...
  18. ncbi request reprint Gtdap-1 and the role of autophagy during planarian regeneration and starvation
    Cristina González-Estévez
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Autophagy 3:640-2. 2007
    ..Our data suggest that autophagy of existing cells may be essential to fuel the continued proliferation and differentiation of stem cells by providing the necessary energy and building blocks to neoblasts...
  19. ncbi request reprint The BMP pathway is essential for re-specification and maintenance of the dorsoventral axis in regenerating and intact planarians
    M Dolores Molina
    Departament de Genetica, Facultat de Biologia, Av Diagonal 645, edifici annex planta 1, 08028 Barcelona, Catalunya, Spain
    Dev Biol 311:79-94. 2007
    ..Our results suggest that the BMP signaling pathway is conserved in planarians and that it plays a key role in the regeneration and maintenance of the dorsoventral axis...
  20. ncbi request reprint Regeneration in planarians and other worms: New findings, new tools, and new perspectives
    Emili Salo
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, 08028 Barcelona, Spain
    J Exp Zool 292:528-39. 2002
    ..This cell could be considered the forebear and a model system for stem-cell analysis...
  21. ncbi request reprint Hox and ParaHox genes in Nemertodermatida, a basal bilaterian clade
    Eva Jimenez-Guri
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Int J Dev Biol 50:675-9. 2006
    ....
  22. ncbi request reprint Stem cells and regeneration in planarians
    Mette Handberg-Thorsager
    Genetics Department, University of Barcelona, Av Diagonal 645, Barcelona, Spain
    Front Biosci 13:6374-94. 2008
    ..In the last ten years, molecular, cellular, and bioinformatics tools have been established for use in this model, making it ideally placed for in vivo analysis of stem cells in their natural environment without ethical complications...
  23. doi request reprint Smed-Evi/Wntless is required for beta-catenin-dependent and -independent processes during planarian regeneration
    Teresa Adell
    Department of Genetics and Institute of Biomedicine of the University of Barcelona, Barcelona, Spain
    Development 136:905-10. 2009
    ..Thus, our study provides evidence that planarian Wnts are major regulators of regeneration, and that they signal through beta-catenin-dependent and -independent pathways...
  24. ncbi request reprint The genetic network of prototypic planarian eye regeneration is Pax6 independent
    David Pineda
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain
    Development 129:1423-34. 2002
    ..Inactivation of both Pax6A and Pax6B by RNA-mediated gene interference (RNAi) inhibits neither eye regeneration nor eye maintenance, suggesting that the genetic network that controls this process is not triggered by Pax6 in planarians...
  25. pmc Gtdap-1 promotes autophagy and is required for planarian remodeling during regeneration and starvation
    Cristina González-Estévez
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain
    Proc Natl Acad Sci U S A 104:13373-8. 2007
    ..Our findings provide insights into the complex interconnections among cell proliferation, homeostasis, and cell death in planarians and perspectives for the understanding of neoblast stem cell dynamics...