S Kashif Sadiq

Summary

Affiliation: Universitat Pompeu Fabra
Country: Spain

Publications

  1. pmc Kinetic characterization of the critical step in HIV-1 protease maturation
    S Kashif Sadiq
    Computational Biophysics Laboratory, GRIB IMIM, Universitat Pompeu Fabra, 08003 Barcelona, Spain
    Proc Natl Acad Sci U S A 109:20449-54. 2012
  2. doi request reprint Explicit solvent dynamics and energetics of HIV-1 protease flap opening and closing
    S Kashif Sadiq
    Computational Biochemistry and Biophysics Lab, GRIB, IMIM UPF, Barcelona Biomedical Research Park, 88 P C 08003 Barcelona, Spain
    Proteins 78:2873-85. 2010
  3. doi request reprint Reaction kinetics of catalyzed competitive heteropolymer cleavage
    S Kashif Sadiq
    Computational Biochemistry and Biophysics Laboratory GRIB IMIM, Universitat Pompeu Fabra, Barcelona Biomedical Research Park PRBB, c Doctor Aiguader 88, 08003 Barcelona, Spain
    J Phys Chem B 115:11017-27. 2011

Collaborators

Detail Information

Publications3

  1. pmc Kinetic characterization of the critical step in HIV-1 protease maturation
    S Kashif Sadiq
    Computational Biophysics Laboratory, GRIB IMIM, Universitat Pompeu Fabra, 08003 Barcelona, Spain
    Proc Natl Acad Sci U S A 109:20449-54. 2012
    ..The shown mechanism also provides an interesting example of molecular conformational transitions along the association pathway...
  2. doi request reprint Explicit solvent dynamics and energetics of HIV-1 protease flap opening and closing
    S Kashif Sadiq
    Computational Biochemistry and Biophysics Lab, GRIB, IMIM UPF, Barcelona Biomedical Research Park, 88 P C 08003 Barcelona, Spain
    Proteins 78:2873-85. 2010
    ..Strategies that take into account multiple flap-gating mechanisms may lead to more effective inhibitors...
  3. doi request reprint Reaction kinetics of catalyzed competitive heteropolymer cleavage
    S Kashif Sadiq
    Computational Biochemistry and Biophysics Laboratory GRIB IMIM, Universitat Pompeu Fabra, Barcelona Biomedical Research Park PRBB, c Doctor Aiguader 88, 08003 Barcelona, Spain
    J Phys Chem B 115:11017-27. 2011
    ..Future investigations that determine the required enzymatic parameters to populate such a scheme will allow for the model to be refined in order to track the time for viral maturation and infectivity...