A Palou

Summary

Affiliation: Universitat de les Illes Balears
Country: Spain

Publications

  1. ncbi request reprint [Nutrigenomics and obesity]
    A Palou
    Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Universitat de les Illes Balears, Palma de Mallorca
    Rev Med Univ Navarra 48:36-48. 2004
  2. pmc Sexual dimorphism in the lasting effects of moderate caloric restriction during gestation on energy homeostasis in rats is related with fetal programming of insulin and leptin resistance
    Mariona Palou
    Laboratory of Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of the Balearic Islands UIB and CIBER Fisiopatología de la Obesidad y Nutrición CIBEROBN, Palma de Mallorca, Spain
    Nutr Metab (Lond) 7:69. 2010
  3. ncbi request reprint General aspects on the assessment of functional foods in the European Union
    A Palou
    Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Departament de Biologia Fonamental i Ciencies de la Salut, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Eur J Clin Nutr 57:S12-7. 2003
  4. pmc Moderate doses of conjugated linoleic acid reduce fat gain, maintain insulin sensitivity without impairing inflammatory adipose tissue status in mice fed a high-fat diet
    Pilar Parra
    University of the Balearic Islands, Cra Valldemossa Km 7, 5, E 07122, Palma de Mallorca, Spain
    Nutr Metab (Lond) 7:5. 2010
  5. doi request reprint Leptin intake during lactation prevents obesity and affects food intake and food preferences in later life
    Andreu Palou
    Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of the Balearic Islands, Palma de Mallorca 07122, and CIBER de Fisiopatología de la Obesidad y Nutrición, Spain
    Appetite 52:249-52. 2009
  6. doi request reprint On the role and fate of sugars in human nutrition and health. Introduction
    A Palou
    Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of the Balearic Islands UIB, Palma de Mallorca, Spain
    Obes Rev 10:1-8. 2009
  7. doi request reprint Nutrient-gene interactions in early life programming: leptin in breast milk prevents obesity later on in life
    Andreu Palou
    Laboratory of Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of the Balearic Islands UIB and CIBER Fisiopatología de la Obesidad y Nutrición CIBEROBN, Palma de Mallorca, Spain
    Adv Exp Med Biol 646:95-104. 2009
  8. doi request reprint Integration of risk and benefit analysis-the window of benefit as a new tool?
    Andreu Palou
    University of the Balearic Islands, Spain
    Crit Rev Food Sci Nutr 49:670-80. 2009
  9. doi request reprint Leptin intake during the suckling period improves the metabolic response of adipose tissue to a high-fat diet
    T Priego
    Laboratory of Molecular Biology, University of the Balearic Islands, Palma de Mallorca, Spain
    Int J Obes (Lond) 34:809-19. 2010
  10. ncbi request reprint Sex-dependent dietary obesity, induction of UCPs, and leptin expression in rat adipose tissues
    A M Rodriguez
    Departament de Biologia Fonamental i Ciencies de la Salut, Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Obes Res 9:579-88. 2001

Collaborators

  • J Sanchez
  • J Ribot
  • A M Rodriguez
  • P Puigserver
  • M J Stock
  • Jaap Keijer
  • F Bouillaud
  • W Ahrens
  • K Bammann
  • Iris Pigeot
  • A Siani
  • P Oliver
  • T Priego
  • C Pico
  • A Caimari
  • M Palou
  • M L Bonet
  • N Granados
  • Catalina Pico
  • N Lopez
  • Pilar Parra
  • A P Garcia
  • Mariona Palou
  • F Felipe
  • J M Ramis
  • J Mercader
  • J L Gonzalez Sanchez
  • J Amengual
  • E Ceresi
  • J von Lintig
  • H Musinović
  • R Díaz-Rúa
  • E Rodriguez
  • J A McKay
  • J C Mathers
  • Teresa Priego
  • Francisca Serra
  • W Rodenburg
  • F Serra
  • P Roca
  • E Villegas
  • O Miralles
  • M T Martinez Larrad
  • A M Proenza
  • C Fernandez Perez
  • M Serrano Rios
  • I Llado
  • N L W Franssen-van Hal
  • E Kramer
  • S Rodriguez-Cuenca
  • B Amengual
  • E Pujol
  • M Monjo
  • M Gianotti

Detail Information

Publications43

  1. ncbi request reprint [Nutrigenomics and obesity]
    A Palou
    Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Universitat de les Illes Balears, Palma de Mallorca
    Rev Med Univ Navarra 48:36-48. 2004
    ....
  2. pmc Sexual dimorphism in the lasting effects of moderate caloric restriction during gestation on energy homeostasis in rats is related with fetal programming of insulin and leptin resistance
    Mariona Palou
    Laboratory of Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of the Balearic Islands UIB and CIBER Fisiopatología de la Obesidad y Nutrición CIBEROBN, Palma de Mallorca, Spain
    Nutr Metab (Lond) 7:69. 2010
    ..We aimed to characterize the lasting effect of moderate caloric restriction during early pregnancy on offspring energy homeostasis, by focusing on the effects on food intake and body weight as well as on the insulin and leptin systems...
  3. ncbi request reprint General aspects on the assessment of functional foods in the European Union
    A Palou
    Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Departament de Biologia Fonamental i Ciencies de la Salut, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Eur J Clin Nutr 57:S12-7. 2003
    ....
  4. pmc Moderate doses of conjugated linoleic acid reduce fat gain, maintain insulin sensitivity without impairing inflammatory adipose tissue status in mice fed a high-fat diet
    Pilar Parra
    University of the Balearic Islands, Cra Valldemossa Km 7, 5, E 07122, Palma de Mallorca, Spain
    Nutr Metab (Lond) 7:5. 2010
    ..In the present study we assessed the potential beneficial effects of CLA mixture (cis-9, trans-11 and trans-10, cis-12, 50:50) in mice fed a high-fat diet...
  5. doi request reprint Leptin intake during lactation prevents obesity and affects food intake and food preferences in later life
    Andreu Palou
    Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of the Balearic Islands, Palma de Mallorca 07122, and CIBER de Fisiopatología de la Obesidad y Nutrición, Spain
    Appetite 52:249-52. 2009
    ..These findings open a new area of research on the use of leptin in the design of more appropriate infant formula, which is significant considering the increasing incidence of obesity and its associated medical complications...
  6. doi request reprint On the role and fate of sugars in human nutrition and health. Introduction
    A Palou
    Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of the Balearic Islands UIB, Palma de Mallorca, Spain
    Obes Rev 10:1-8. 2009
    ....
  7. doi request reprint Nutrient-gene interactions in early life programming: leptin in breast milk prevents obesity later on in life
    Andreu Palou
    Laboratory of Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of the Balearic Islands UIB and CIBER Fisiopatología de la Obesidad y Nutrición CIBEROBN, Palma de Mallorca, Spain
    Adv Exp Med Biol 646:95-104. 2009
    ..Recent data from our laboratory, identifying leptin as the first specific compound responsible for these beneficial effects, are reviewed and discussed...
  8. doi request reprint Integration of risk and benefit analysis-the window of benefit as a new tool?
    Andreu Palou
    University of the Balearic Islands, Spain
    Crit Rev Food Sci Nutr 49:670-80. 2009
    ..Ultimately this should lead to an integrated risk-benefit assessment, which will allow better management and, especially, communication, to the benefit of the consumer...
  9. doi request reprint Leptin intake during the suckling period improves the metabolic response of adipose tissue to a high-fat diet
    T Priego
    Laboratory of Molecular Biology, University of the Balearic Islands, Palma de Mallorca, Spain
    Int J Obes (Lond) 34:809-19. 2010
    ..The intake of leptin during the suckling period protects against obesity and improves insulin and central leptin sensitivity in adult rats...
  10. ncbi request reprint Sex-dependent dietary obesity, induction of UCPs, and leptin expression in rat adipose tissues
    A M Rodriguez
    Departament de Biologia Fonamental i Ciencies de la Salut, Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Obes Res 9:579-88. 2001
    ....
  11. ncbi request reprint Changes of adiposity in response to vitamin A status correlate with changes of PPAR gamma 2 expression
    J Ribot
    Depertment of Fundamental Biology and Health Sciences, University of Illes Balears, Palma de Mallorca, Spain
    Obes Res 9:500-9. 2001
    ..DISCUSSION: The results emphasize the importance of retinoids as physiological regulators of adipose tissue development and function in intact animals...
  12. doi request reprint Response to carbohydrate and fat refeeding in the expression of genes involved in nutrient partitioning and metabolism: striking effects on fibroblast growth factor-21 induction
    J Sanchez
    University of the Balearic Islands and Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición, Palma de Mallorca 07122, Spain
    Endocrinology 150:5341-50. 2009
    ....
  13. ncbi request reprint Differential expression of genes for uncoupling proteins 1, 2 and 3 in brown and white adipose tissue depots during rat development
    P Oliver
    , Universitat de les Illes Balears, Palma de Mallorca, Spain
    Cell Mol Life Sci 58:470-6. 2001
    ..In contrast to ucp1 and ucp3, ucp2 had a peak of expression at about 2 months, and lower expression at 3 months, suggesting different regulation and probably a different role for this UCP...
  14. ncbi request reprint Sexual dimorphism in the adrenergic control of rat brown adipose tissue response to overfeeding
    E Rodriguez
    Departament de Biologia Molecular, Nutricó i Biotecnologia, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Pflugers Arch 442:396-403. 2001
    ..Thus, the alpha2/beta3 balance in BAT could be a key in the thermogenic control...
  15. ncbi request reprint Weight loss reduces expression of SREBP1c/ADD1 and PPARgamma2 in adipose tissue of obese women
    J Ribot
    Departament de Biologia Fonamental i Ciencies de la Salut, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Pflugers Arch 441:498-505. 2001
    ..Our results suggest a functional role for SREBP1c/ADD1 and PPARgamma2 in the control of energy metabolism in human adipose tissue...
  16. doi request reprint Sequential changes in the expression of genes involved in lipid metabolism in adipose tissue and liver in response to fasting
    M Palou
    Biologia Molecular, Nutrición y Biotecnología Nutrigenómica, Universidad de las Islas Baleares UIB, Palma de Mallorca, Spain
    Pflugers Arch 456:825-36. 2008
    ....
  17. doi request reprint Impairment of nutritional regulation of adipose triglyceride lipase expression with age
    A Caimari
    Laboratory of Molecular Biology, Nutrition and Biotechnology, Universitat de les Illes Balears and CIBER de Fisiopatología de la Obesidad y Nutrición, CIBEROBN, Palma de Mallorca, Spain
    Int J Obes (Lond) 32:1193-200. 2008
    ..Fasting-induced lipolysis becomes less effective with age. We have studied whether nutritional regulation of adipose triglyceride lipase (ATGL)--with an important role in lipolysis in low energy states--is affected by age...
  18. doi request reprint Dietary l-leucine supplementation of lactating rats results in a tendency to increase lean/fat ratio associated to lower orexigenic neuropeptide expression in hypothalamus
    N Lopez
    Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of the Balearic Islands UIB and CIBER Fisiopatología de la Obesidad y Nutrición CIBEROBN, Palma de Mallorca, Spain
    Peptides 31:1361-7. 2010
    ....
  19. ncbi request reprint The intake of physiological doses of leptin during lactation in rats prevents obesity in later life
    C Pico
    Departamento de Biología Fundamental y Ciencias de la Salud, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Int J Obes (Lond) 31:1199-209. 2007
    ..Breast milk contains leptin, a hormone that regulates food intake and energy expenditure, and previous studies in rats have shown that leptin orally administered during lactation exerts anorexigenic effects...
  20. doi request reprint Moderate caloric restriction during gestation results in lower arcuate nucleus NPY- and alphaMSH-neurons and impairs hypothalamic response to fed/fasting conditions in weaned rats
    A P Garcia
    Laboratory of Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of Balearic Islands and CIBER Fisiopatología de la Obesidad y Nutrición CIBEROBN, Palma de Mallorca, Spain
    Diabetes Obes Metab 12:403-13. 2010
    ..We aimed to characterize the developmental programming effects of moderate caloric restriction during early pregnancy on factors involved in hypothalamic control of energy balance...
  21. ncbi request reprint Obesity: molecular bases of a multifactorial problem
    A Palou
    Departament de Biologia Fonamental i Ciencies de la Salut, Bioquimica i Biologia Molecular, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Eur J Nutr 39:127-44. 2000
    ....
  22. ncbi request reprint "In vivo" glutamic acid metabolism in late pregnant rats
    P Roca
    , , Universitat de les Illes Balears, Valldemossa, Palma de Mallorca, Spain
    Horm Metab Res 25:294-7. 1993
    ....
  23. ncbi request reprint Uncoupling proteins: gender dependence and their relation to body weight control
    A M Rodriguez
    Departament de Biologia Fonamental i Ciencies de la Salut, Ed Guillem Colom, Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Int J Obes Relat Metab Disord 28:500-2. 2004
    ....
  24. doi request reprint Slc27a2 expression in peripheral blood mononuclear cells as a molecular marker for overweight development
    A Caimari
    Laboratory of Molecular Biology, Nutrition and Biotechnology, Universitat de les Illes Balears and CIBER de Fisiopatología de la Obesidad y Nutrición CIBEROBN, Palma de Mallorca, Spain
    Int J Obes (Lond) 34:831-9. 2010
    ..Obesity is becoming the most common health problem of the 21st century, being dietary intake an important determinant of this pathology and numerous chronic health conditions...
  25. ncbi request reprint Involvement of the retinoblastoma protein in brown and white adipocyte cell differentiation: functional and physical association with the adipogenic transcription factor C/EBPalpha
    P Puigserver
    Departament de Biologia Fonamental i Ciencies de la Salut, Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Eur J Cell Biol 77:117-23. 1998
    ....
  26. doi request reprint Retinol-binding protein 4 and nicotinamide phosphoribosyltransferase/visfatin in rat obesity models
    J Mercader
    Laboratory of Molecular Biology, Nutrition and Biotechnology, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Horm Metab Res 40:467-72. 2008
    ..Hence, increases in RBP4 or Nampt/visfatin do not accompany obesity and insulin resistance in the models examined...
  27. doi request reprint Diet-induced obesity affects expression of adiponutrin/PNPLA3 and adipose triglyceride lipase, two members of the same family
    P Oliver
    Laboratory of Molecular Biology, Nutrition and Biotechnology, Universitat de Illes Balears and CIBER de Fisiopatología de Obesidad y Nutrición, Palma de Mallorca, Spain
    Int J Obes (Lond) 36:225-32. 2012
    ..Gene expression of both proteins and their nutritional regulation have been described to be altered in genetically obese animals...
  28. ncbi request reprint Body weight and tissue composition in rats made obese by a cafeteria diet. Effect of 24 hours starvation
    M Gianotti
    Departamento de Biologia i Ciencias de la Slut (Laboratori de Bioquimica, Universitat de les Illes Balears, Fac. de Ciencies, Spain
    Horm Metab Res 20:208-12. 1988
    ..The overall cafeteria fed versus chow fed rat differences in the effects of a 24 hour starvation, were minor but less liver glycogen and much more skeletal muscle lipids were mobilized in the cafeteria fed rats than in controls...
  29. ncbi request reprint Uncoupling proteins: gender-dependence and their relation to body weight control
    A M Rodriguez
    Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Departament de Biologia Fonamental i Ciencies de la Salut, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Int J Obes Relat Metab Disord 28:327-9. 2004
    ....
  30. ncbi request reprint Effect of selective beta-adrenoceptor stimulation on UCP synthesis in primary cultures of brown adipocytes
    P Puigserver
    Dept de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Mol Cell Endocrinol 117:7-16. 1996
    ..However, all three beta AR subtypes do not become fully functional until cultured cells become confluent...
  31. ncbi request reprint Ontogenesis of leptin expression in different adipose tissue depots in the rat
    P Oliver
    , Universitat de les Illes Balears, Palma de Mallorca, Spain
    Pflugers Arch 442:383-90. 2001
    ....
  32. doi request reprint Protective effects of leptin during the suckling period against later obesity may be associated with changes in promoter methylation of the hypothalamic pro-opiomelanocortin gene
    M Palou
    Laboratory of Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of the Balearic Islands, Carretera Valldemossa Km 7 5, Palma de Mallorca 07122, Spain
    Br J Nutr 106:769-78. 2011
    ....
  33. ncbi request reprint Vitamin A and the regulation of fat reserves
    M L Bonet
    Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Departament de Biologia Fonamental i Ciencies de la Salut, Universitat de les Illes Balears, Cra Valldemossa Km 7 5, 07071 Palma de Mallorca, Spain
    Cell Mol Life Sci 60:1311-21. 2003
    ..Moreover, vitamin A status can influence the development and function of adipose tissues in whole animals, with a low vitamin A status favouring increased fat deposition...
  34. ncbi request reprint Resistin as a putative modulator of insulin action in the daily feeding/fasting rhythm
    P Oliver
    Laboratory of Molecular Biology, Nutrition and Biotechnology, Department of Fundamental Biology and Health Sciences, University of the Balearic Islands, Cra Valldemossa Km 7 5, 07122, Palma de Mallorca, Spain
    Pflugers Arch 452:260-7. 2006
    ....
  35. doi request reprint Vitamin A supplementation in early life affects later response to an obesogenic diet in rats
    N Granados
    Laboratory of Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of the Balearic Islands and CIBER Fisiopatología de la Obesidad y Nutrición CIBERobn, Palma de Mallorca, Spain
    Int J Obes (Lond) 37:1169-76. 2013
    ..Conclusion:Vitamin A intake in the early stages of postnatal life favors subsequent HF diet-induced adiposity gain through mechanisms that may relate to changes in adipose tissue development, likely mediated by RA. ..
  36. ncbi request reprint [New challenges in basic and applied nutrition]
    A Palou
    Laboratorio de Biologia Molecular, Nutrición y Biotecnología Nutrigenómica, Universitat de les Illes Balears, Palma de Mallorca
    Rev Med Univ Navarra 50:62-70. 2006
    ..g. nutrigenomics) are emerging and new trends towards a more conscious, better informed, consumer are foreseen that will allow an appropriate reaction to these new challenges in the medium and long term...
  37. pmc Effect of high-fat diet feeding on leptin receptor expression in white adipose tissue in rats: depot- and sex-related differential response
    T Priego
    Laboratory of Molecular Biology, Nutrition and Biotechnology Nutrigenomics, University of the Balearic Islands UIB and CIBER Fisiopatología de la Obesidad y Nutrición CIBEROBN, 07122, Palma de Mallorca, Spain
    Genes Nutr 4:151-6. 2009
    ....
  38. ncbi request reprint Opposite actions of testosterone and progesterone on UCP1 mRNA expression in cultured brown adipocytes
    A M Rodriguez
    Departament de Biologia Fonamental i Ciencies de la Salut, Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Universitat de les Illes Balears, Cra Valldemossa, km 7 5, Palma de Mallorca 07071, Spain
    Cell Mol Life Sci 59:1714-23. 2002
    ....
  39. ncbi request reprint Up-regulation of muscle uncoupling protein 3 gene expression in mice following high fat diet, dietary vitamin A supplementation and acute retinoic acid-treatment
    F Felipe
    Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Departament de Biologia Fonamental i Ciencies de la Salut, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Int J Obes Relat Metab Disord 27:60-9. 2003
    ..To analyse the impact of vitamin A supplementation of both a normal fat (NF) diet and a high fat (HF) diet and of acute retinoic acid (RA)-treatment on the expression of uncoupling protein 3 (UCP3) in mice...
  40. ncbi request reprint Carboxypeptidase E and thrombospondin-1 are differently expressed in subcutaneous and visceral fat of obese subjects
    J M Ramis
    Department of Fundamental Biology and Health Sciences, University of the Balearic Islands, Palma de Mallorca, Spain
    Cell Mol Life Sci 59:1960-71. 2002
    ..The involvement of CPE and THBS1 in obesity allows us to suggest that the physiological processes controlled by these genes contribute to depot and gender-related differences in the metabolic complications of obesity...
  41. ncbi request reprint The glutamine 27 glutamic acid polymorphism of the beta2-adrenoceptor gene is associated with abdominal obesity and greater risk of impaired glucose tolerance in men but not in women: a population-based study in Spain
    J L Gonzalez Sanchez
    Departamento de Medicina Interna II, Hospital Universitario Clinico San Carlos, Madrid, Spain
    Clin Endocrinol (Oxf) 59:476-81. 2003
    ....
  42. ncbi request reprint [Genetic polymorphisms and new perspectives in the prevention and treatment of obesity]
    A Palou
    Departamento de Biología Fundamental y Ciencias de la Salud, Universidad de las Islas Baleares, Espana
    Nutr Hosp 17:23-33. 2002
    ....
  43. ncbi request reprint Understanding and preventing childhood obesity and related disorders--IDEFICS: a European multilevel epidemiological approach
    W Ahrens
    Division of Epidemiological Methods and Etiologic Research, Bremen Institute for Prevention Research and Social Medicine BIPS, University of Bremen, Linzer Strasse 10, D 28359 Bremen, Germany
    Nutr Metab Cardiovasc Dis 16:302-8. 2006
    ..We will propose knowledge-based guidelines on dietary and lifestyle activities for health promotion and disease prevention in children for health professionals, stakeholders and consumers...