Andres Ozaita

Summary

Affiliation: Universitat Pompeu Fabra
Country: Spain

Publications

  1. ncbi request reprint Regulation of PI3K/Akt/GSK-3 pathway by cannabinoids in the brain
    Andres Ozaita
    Laboratori de Neurofarmacologia Facultat de Ciencies de la Salut i de la Vida Universitat Pompeu Fabra, Barcelona, Spain
    J Neurochem 102:1105-14. 2007
  2. pmc Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids
    Emma Puighermanal
    Departament de Ciencies Experimentals i de la Salut, Facultat de Ciencies de la Salut i de la Vida, Universitat Pompeu Fabra, Barcelona, Spain
    Philos Trans R Soc Lond B Biol Sci 367:3254-63. 2012
  3. pmc Dissociation of the pharmacological effects of THC by mTOR blockade
    Emma Puighermanal
    Laboratori de Neurofarmacologia, Departament de Ciencies Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain
    Neuropsychopharmacology 38:1334-43. 2013
  4. pmc Microglial activation underlies cerebellar deficits produced by repeated cannabis exposure
    Laura Cutando
    Laboratori de Neurofarmacologia, Facultat de Ciències de Salut i de Vida, Universitat Pompeu Fabra, Barcelona, Spain
    J Clin Invest 123:2816-31. 2013
  5. doi request reprint Targeting the endocannabinoid system in the treatment of fragile X syndrome
    Arnau Busquets-Garcia
    Departament de Ciències Experimentals i de la Salut DCEXS, Universitat Pompeu Fabra UPF, Barcelona, Spain
    Nat Med 19:603-7. 2013
  6. ncbi request reprint Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses
    Arnau Busquets-Garcia
    Facultat de Ciencies de la Salut i de la Vida, Universitat Pompeu Fabra, Barcelona, Spain
    Biol Psychiatry 70:479-86. 2011
  7. doi request reprint Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling
    Emma Puighermanal
    Laboratori de Neurofarmacologia, Facultat de Ciencies de la Salut i de la Vida, Universitat Pompeu Fabra, Barcelona, Spain
    Nat Neurosci 12:1152-8. 2009
  8. doi request reprint Genes differentially expressed in CB1 knockout mice: involvement in the depressive-like phenotype
    Ester Aso
    Laboratori de Neurofarmacologia, Departament de Ciències Experimentals i de Salut, Universitat Pompeu Fabra, PRBB, Barcelona, Spain
    Eur Neuropsychopharmacol 21:11-22. 2011

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Regulation of PI3K/Akt/GSK-3 pathway by cannabinoids in the brain
    Andres Ozaita
    Laboratori de Neurofarmacologia Facultat de Ciencies de la Salut i de la Vida Universitat Pompeu Fabra, Barcelona, Spain
    J Neurochem 102:1105-14. 2007
    ..In addition, THC increased the phosphorylation of glycogen synthase kinase 3 beta. Therefore, activation of the PI3K/Akt/GSK-3 signaling pathway may be related to the in vivo neuroprotective properties attributed to cannabinoids...
  2. pmc Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids
    Emma Puighermanal
    Departament de Ciencies Experimentals i de la Salut, Facultat de Ciencies de la Salut i de la Vida, Universitat Pompeu Fabra, Barcelona, Spain
    Philos Trans R Soc Lond B Biol Sci 367:3254-63. 2012
    ..In this study, we summarize the cellular and molecular mechanisms reported in the modulation of cognitive function by the endocannabinoid system...
  3. pmc Dissociation of the pharmacological effects of THC by mTOR blockade
    Emma Puighermanal
    Laboratori de Neurofarmacologia, Departament de Ciencies Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain
    Neuropsychopharmacology 38:1334-43. 2013
    ..Altogether, these results provide new insights for targeting the endocannabinoid system in order to prevent possible side effects...
  4. pmc Microglial activation underlies cerebellar deficits produced by repeated cannabis exposure
    Laura Cutando
    Laboratori de Neurofarmacologia, Facultat de Ciències de Salut i de Vida, Universitat Pompeu Fabra, Barcelona, Spain
    J Clin Invest 123:2816-31. 2013
    ..Our results suggest that cerebellar microglial activation plays a crucial role in the cerebellar deficits induced by repeated cannabis exposure...
  5. doi request reprint Targeting the endocannabinoid system in the treatment of fragile X syndrome
    Arnau Busquets-Garcia
    Departament de Ciències Experimentals i de la Salut DCEXS, Universitat Pompeu Fabra UPF, Barcelona, Spain
    Nat Med 19:603-7. 2013
    ..Some of these traits were also reversed by pharmacological inhibition of mTOR or mGluR5. Thus, blockade of ECS is a potential therapeutic approach to normalize specific alterations in FXS...
  6. ncbi request reprint Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses
    Arnau Busquets-Garcia
    Facultat de Ciencies de la Salut i de la Vida, Universitat Pompeu Fabra, Barcelona, Spain
    Biol Psychiatry 70:479-86. 2011
    ..An alternative approach to circumvent this limitation consists of enhancing the concentration of the endocannabinoids anandamide and 2-arachidonoylglycerol...
  7. doi request reprint Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling
    Emma Puighermanal
    Laboratori de Neurofarmacologia, Facultat de Ciencies de la Salut i de la Vida, Universitat Pompeu Fabra, Barcelona, Spain
    Nat Neurosci 12:1152-8. 2009
    ....
  8. doi request reprint Genes differentially expressed in CB1 knockout mice: involvement in the depressive-like phenotype
    Ester Aso
    Laboratori de Neurofarmacologia, Departament de Ciències Experimentals i de Salut, Universitat Pompeu Fabra, PRBB, Barcelona, Spain
    Eur Neuropsychopharmacol 21:11-22. 2011
    ..Several genes coding for neurotransmitter receptors, neurotrophic factors, neuropeptides and hormones receptors were differentially expressed in CB(1) knockout mice...