Felix Grases

Summary

Affiliation: Universitat de les Illes Balears
Country: Spain

Publications

  1. ncbi request reprint Urinary phytate (Myo-inositol hexaphosphate) in healthy school children and risk of nephrolithiasis
    Felix Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University Institute of Health Sciences Research IUNICS IdISPa, University of Balearic Islands, Palma de Mallorca, Spain Electronic address
    J Ren Nutr 24:219-23. 2014
  2. doi request reprint Structure and formation mechanism of calcium phosphate concretions formed in simulated body fluid
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122, Palma de Mallorca, Spain
    Urolithiasis 42:9-16. 2014
  3. pmc Renal papillary calcification and the development of calcium oxalate monohydrate papillary renal calculi: a case series study
    Felix Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, Universitary Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma de Mallorca, 07122, Spain
    BMC Urol 13:14. 2013
  4. pmc Factors affecting calcium oxalate dihydrate fragmented calculi regrowth
    A Costa-Bauza
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122 Palma of Mallorca, Spain
    BMC Urol 6:16. 2006
  5. pmc Lemon juice has protective activity in a rat urolithiasis model
    Mohammed Touhami
    Laboratory of Animal Physiology, Ecophysiology Unit, Department of Biology, Faculty of Sciences Semlalia, University Cadi Ayyad, PO Box 2390, Marrakech, 40000, Morocco
    BMC Urol 7:18. 2007
  6. ncbi request reprint Influence of concomitant food intake on the excretion of orally administered myo-inositol hexaphosphate in humans
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institut of Health Sciences Research, University of Balearic Islands, Palma of Mallorca, Spain
    J Med Food 9:72-6. 2006
  7. ncbi request reprint Uric acid as inducer of calcium oxalate crystal development
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma de Mallorca, Spain
    Scand J Urol Nephrol 41:26-31. 2007
  8. ncbi request reprint Structural features of three ureterocele calculi
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institute for Health Sciences Research, Ed Mateu Orfila Rotger, University of Balearic Islands, Ctra Valldemossa km 7 5, 07122, Palma de Mallorca, Spain
    Int Urol Nephrol 39:765-9. 2007
  9. ncbi request reprint Phytate acts as an inhibitor in formation of renal calculi
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma of Mallorca, Spain
    Front Biosci 12:2580-7. 2007
  10. pmc Renal lithiasis and nutrition
    Felix Grases
    Laboratory of Renal Lithiasis Research, Universitary Institute of Health Sciences Research IUNICS, University of Balearic Islands, E 07122 Palma de Mallorca, Spain
    Nutr J 5:23. 2006

Collaborators

  • Antonia Costa-Bauza
  • Rafael M Prieto
  • Antoni Payeras
  • Juan G March
  • Ivana Vucenik
  • Zhi Wang
  • Angela Conte
  • Daniel Muñoz-Velez
  • Miguel Fiol
  • Emilio Ros
  • Concepción Sáez-Torres
  • Enrique Pieras
  • Joan Perello
  • Dolores Rodrigo
  • Cristina Gomez
  • Ángel A López-González
  • Diego Alonso
  • A A López-González
  • Mohammed Touhami
  • G Grases
  • Bartolome M Simonet
  • Ana M García-Raja
  • Javier Lumbreras
  • Guiem Frontera
  • Bartolome Mari
  • Fernando Tur
  • Nieves Monroy
  • Ma Teófila Vicente-Herrero
  • Guillem Frontera
  • Ana María García-Raja
  • Pedro Pizá
  • B M Simonet
  • P Roca
  • M T Vicente-Herrero
  • B Mari
  • Abderrahman Chait
  • Ibtissam Zrara
  • Khadija Elhabazi
  • Younes Eljahiri
  • Amine Laroubi
  • Farouk Loubna
  • Abdelkhalek Oussama
  • Margarita Ramis
  • J Perello
  • J A Pérez-Castelló
  • E Rigo
  • B Isern
  • P Sanchis
  • A Casero
  • Pilar Sanchis

Detail Information

Publications70

  1. ncbi request reprint Urinary phytate (Myo-inositol hexaphosphate) in healthy school children and risk of nephrolithiasis
    Felix Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University Institute of Health Sciences Research IUNICS IdISPa, University of Balearic Islands, Palma de Mallorca, Spain Electronic address
    J Ren Nutr 24:219-23. 2014
    ..The aim of this study was to assess, for the first time, the urinary levels of phytate in children and to correlate these levels with other urinary parameters related to crystallization risk and to general dietary habits...
  2. doi request reprint Structure and formation mechanism of calcium phosphate concretions formed in simulated body fluid
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122, Palma de Mallorca, Spain
    Urolithiasis 42:9-16. 2014
    ....
  3. pmc Renal papillary calcification and the development of calcium oxalate monohydrate papillary renal calculi: a case series study
    Felix Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, Universitary Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma de Mallorca, 07122, Spain
    BMC Urol 13:14. 2013
    ..The objective of this study is to determine in a case series (four patients) how calcified deposits in renal papillae are associated with the development of calcium oxalate monohydrate (COM) papillary calculi...
  4. pmc Factors affecting calcium oxalate dihydrate fragmented calculi regrowth
    A Costa-Bauza
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122 Palma of Mallorca, Spain
    BMC Urol 6:16. 2006
    ..This study examined the effect of various urinary conditions and crystallization inhibitors on the regrowth of spontaneously-passed post-ESWL COD calculi fragments...
  5. pmc Lemon juice has protective activity in a rat urolithiasis model
    Mohammed Touhami
    Laboratory of Animal Physiology, Ecophysiology Unit, Department of Biology, Faculty of Sciences Semlalia, University Cadi Ayyad, PO Box 2390, Marrakech, 40000, Morocco
    BMC Urol 7:18. 2007
    ..Nevertheless the exact mechanism of the preventive effects of these products is still far to be clearly established, being its knowledge necessary to successfully apply these therapies to avoid stone formation...
  6. ncbi request reprint Influence of concomitant food intake on the excretion of orally administered myo-inositol hexaphosphate in humans
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institut of Health Sciences Research, University of Balearic Islands, Palma of Mallorca, Spain
    J Med Food 9:72-6. 2006
    ..Thus, if InsP6 supplements of vegetal origin are consumed to maintain the optimum InsP6 levels needed for a healthy status, these supplements can be consumed either during or between meals with the same efficacy...
  7. ncbi request reprint Uric acid as inducer of calcium oxalate crystal development
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma de Mallorca, Spain
    Scand J Urol Nephrol 41:26-31. 2007
    ..This paper deals with the mechanism by which uric acid affects calcium oxalate crystallization and the role of crystallization inhibitors in this process...
  8. ncbi request reprint Structural features of three ureterocele calculi
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institute for Health Sciences Research, Ed Mateu Orfila Rotger, University of Balearic Islands, Ctra Valldemossa km 7 5, 07122, Palma de Mallorca, Spain
    Int Urol Nephrol 39:765-9. 2007
    ....
  9. ncbi request reprint Phytate acts as an inhibitor in formation of renal calculi
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma of Mallorca, Spain
    Front Biosci 12:2580-7. 2007
    ..The findings show that the action of phytate as a crystallization inhibitor takes place both in the intrapapillary tissue and urine...
  10. pmc Renal lithiasis and nutrition
    Felix Grases
    Laboratory of Renal Lithiasis Research, Universitary Institute of Health Sciences Research IUNICS, University of Balearic Islands, E 07122 Palma de Mallorca, Spain
    Nutr J 5:23. 2006
    ....
  11. ncbi request reprint Absorption of myo-inositol hexakisphosphate (InsP6) through the skin in humans
    F Grases
    Laboratory of Renal Lithiasis Research, Institute of Health Sciences Research, Faculty of Sciences, University of Balearic Islands, 07122 Palma de Mallorca, Spain
    Pharmazie 61:652. 2006
    ..These results demonstrate the topical application as a suitable administration route of InsP6 in humans...
  12. ncbi request reprint Intracellular and extracellular myo-inositol hexakisphosphate (InsP6), from rats to humans
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institute of Health Sciences Research, University of Balearic Islands, E 07122 Palma of Mallorca, Spain
    Anticancer Res 25:2593-7. 2005
    ..From these results, it can be deduced that health benefits linked to extracellular InsP6 must be related to dietary InsP6...
  13. ncbi request reprint Phytate (Myo-inositol hexakisphosphate) inhibits cardiovascular calcifications in rats
    Felix Grases
    University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma of Mallorca, Spain
    Front Biosci 11:136-42. 2006
    ..Only InsP6 non-treated rats displayed important mineral deposits in aorta and heart. These findings are consistent with the action of InsP6, as an inhibitor of calcification of cardiovascular system...
  14. ncbi request reprint Role of uric acid in different types of calcium oxalate renal calculi
    Felix Grases
    Laboratory of Renal Lithiasis Research, Institute of Health Sciences Research IUNICS, University of Balearic Islands, Mallorca, Spain
    Int J Urol 13:252-6. 2006
    ..The presence of uric acid in the beginning zone of different types of 'pure' calcium oxalate renal calculi was evaluated with the aim of establishing the degree of participation of uric acid crystals in the formation of such calculi...
  15. doi request reprint Melamine urinary bladder stone
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institute of Health Science Research, University of Balearic Islands, Palma de Mallorca, Spain
    Urology 73:1262-3. 2009
    ..We report a unique case of a melamine bladder urinary stone. A physiopathologic mechanism of formation is proposed and discussed...
  16. ncbi request reprint Effect of crystallization inhibitors on vascular calcifications induced by vitamin D: a pilot study in Sprague-Dawley rats
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma of Mallorca, Spain
    Circ J 71:1152-6. 2007
    ..The present study investigated the capacity of etidronate (a bisphosphonate used in osteoporosis treatment) and phytate (a natural product) to inhibit vascular calcification in rats...
  17. doi request reprint Phytate inhibits bovine pericardium calcification in vitro
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma of Mallorca, Spain
    Cardiovasc Pathol 17:139-45. 2008
    ..The present study examined the inhibitory effects of pyrophosphate, etidronate, and phytate on bovine pericardium calcification in vitro...
  18. doi request reprint Non-infectious phosphate renal calculi: fine structure, chemical and phase composition
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma de Mallorca, Spain
    Scand J Clin Lab Invest 71:407-12. 2011
    ..Chemical composition of internally non-homogeneous phosphate stones should be related to the conditions prevailing during the formation of each individual part...
  19. doi request reprint Effect of tetracalcium dimagnesium phytate on bone characteristics in ovariectomized rats
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research, University of Balearic Islands, Madrid, Spain
    J Med Food 13:1301-6. 2010
    ..Thus, phytate exhibits effects similar to those of bisphosphonates on bone resorption and may be of use in the primary prevention of osteoporosis if larger studies in humans confirm these findings...
  20. doi request reprint Origin and types of calcium oxalate monohydrate papillary renal calculi
    Felix Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, Universitary Institute of Health Sciences Research, University of Balearic Islands, Palma de Mallorca, Spain
    Urology 76:1339-45. 2010
    ..To assess the mechanism of formation, we sought to correlate the fine structure of papillary renal calculi with specific pathophysiologic conditions and urinary alterations...
  21. ncbi request reprint Evolution of post-ESWL residual lithiasis depending on the type of calculus and urine composition
    Felix Grases
    Laboratorio de Investigación en Litiasis Renal, Instituto Universitario de Investigación en Ciencias de la Salud IUNICS, Universitat de les Illes Balears, Palma de Mallorca, Spain
    Arch Esp Urol 62:473-82. 2009
    ....
  22. doi request reprint A potential role for crystallization inhibitors in treatment of Alzheimer's disease
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Spain
    Med Hypotheses 74:118-9. 2010
    ..Therefore, the absence of crystallization inhibitors may be a risk factor for development of Alzheimer's disease, and this hypothesis should be evaluated...
  23. doi request reprint Phytotherapy and renal stones: the role of antioxidants. A pilot study in Wistar rats
    Felix Grases
    Faculty of Sciences, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma de Mallorca, Spain
    Urol Res 37:35-40. 2009
    ..These results demonstrate the ability of herbal preparations and antioxidants to prevent the development of papillary and intratubular calcification in the kidney...
  24. doi request reprint Anticalculus effect of a triclosan mouthwash containing phytate: a double-blind, randomized, three-period crossover trial
    F Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research, University of Balearic Islands, Palma de Mallorca, Spain
    J Periodontal Res 44:616-21. 2009
    ..The aim of the present study was to examine the effects of phytate and zinc, administered in a mouthwash solution, to prevent the formation of dental calculus...
  25. ncbi request reprint Role of phytate and osteopontin in the mechanism of soft tissue calcification
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma of Mallorca, Spain
    J Nephrol 21:768-75. 2008
    ..The present study examined the role of phytate and osteopontin during the development of soft tissue calcification in an animal model...
  26. ncbi request reprint Phytate reduces age-related cardiovascular calcification
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research, University of Balearic Islands, Palma de Mallorca, Spain
    Front Biosci 13:7115-22. 2008
    ..The present study demonstrated that dietary phytate treatment significantly reduced age-related aorta calcification...
  27. ncbi request reprint Study of a myo-inositol hexaphosphate-based cream to prevent dystrophic calcinosis cutis
    F Grases
    Laboratory of Renal Lithiasis Research and Biomineralization, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122 Palma de Mallorca, Spain
    Br J Dermatol 152:1022-5. 2005
    ..Myo-inositol hexaphosphate (InsP(6)) is a diet-dependent molecule found in all mammalian fluids and tissues, which exhibits an extraordinary capacity as a crystallization inhibitor of calcium salts...
  28. ncbi request reprint Study of the absorption of myo-inositol hexakisphosphate (InsP6) through the skin
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma of Mallorca, Spain
    Biol Pharm Bull 28:764-7. 2005
    ....
  29. ncbi request reprint Absorption of myo-inositol hexakisphosphate (InsP6) through the skin: study of the matrix effects. mechanism of phytate topical absorption
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Palma of Mallorca, Spain
    Front Biosci 10:799-802. 2005
    ....
  30. doi request reprint Urinary pH and renal lithiasis
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122 Palma de Mallorca, Spain
    Urol Res 40:41-6. 2012
    ..5 and 6.0 because the injured papilla acts as a heterogeneous nucleant. Consequently, measurement of urinary pH may be used to evaluate the lithogen risk of given urine...
  31. ncbi request reprint Recurrence of renal lithiasis
    Felix Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University of Balearic Islands, Palma de Mallorca, Spain
    Scand J Urol Nephrol 37:482-6. 2003
    ..It is well known that all renal stones are associated with a high recurrence rate. The aim of this paper is to study the different types of renal calculi recurrence...
  32. ncbi request reprint Effects of exogenous inositol hexakisphosphate (InsP(6)) on the levels of InsP(6) and of inositol trisphosphate (InsP(3)) in malignant cells, tissues and biological fluids
    Felix Grases
    Laboratory of Renal Lithiasis Research, Faculty of Science, University of Balearic Islands, Ctra Valldemossa km 7 5, 07071 Palma de Mallorca, Spain
    Life Sci 71:1535-46. 2002
    ..Although a similar fluctuation of InsP(6) concentration was not seen in human malignant cell lines following InsP(6) treatment, an increased intracellular levels of total InsP(3) was clearly observed...
  33. ncbi request reprint Study of potassium phytate effects on decreasing urinary calcium in rats
    F Grases
    Laboratorio de Investigación en Litiasis Renal, University of Balearic Islands, Palma de Mallorca, Spain
    Urol Int 72:237-43. 2004
    ....
  34. ncbi request reprint Dietary myo-inositol hexaphosphate prevents dystrophic calcifications in soft tissues: a pilot study in Wistar rats
    F Grases
    Laboratory of Renal Lithiasis Research, Institute of Health Sciences IUNICS, University of Balearic Islands, Ctra Valldemossa km 7 5, 07071, Palma de Mallorca, Spain
    Life Sci 75:11-9. 2004
    ..3-0.4 microM) clearly inhibited the development of dystrophic calcifications in soft tissues. These results demonstrates that myo-inositol hexaphosphate acts as an inhibitor of calcium salt crystallization...
  35. ncbi request reprint Effect of phytate on element bioavailability in the second generation of rats
    F Grases
    Laboratorio de Investigación en Litiasis Renal, Facultad de Ciencias, Universitat de les Illes Balears, Palma de Mallorca, Spain
    J Trace Elem Med Biol 17:229-34. 2004
    ..However, using this purified diet, the zinc concentration in bone resulted around 10 times higher than found in rats fed with a common non purified rat chow...
  36. ncbi request reprint The role of glycoproteins in calcium oxalate crystal development
    Felix Grases
    Laboratory of Renal Lithiasis Research, Institute of Health Sciences Research IUNICS, University of Balearic Islands Palma de Mallorca, Spain
    BJU Int 94:177-81. 2004
    ..To assess the effects of a glycoprotein (mucine) on calcium oxalate crystal development in different conditions and situations, to clarify some of its possible effects...
  37. ncbi request reprint Role of the organic matter in calcium oxalate lithiasis
    Felix Grases
    Laboratory of Renal Lithiasis Research, Institute of Health Sciences Research, University of Balearic Islands, Palma de Mallorca, Spain
    Front Biosci 10:1534-8. 2005
    ..These findings show that cell debris provides the necessary elements for the development of oxalate crystals and that this process can be effectively inhibited by presence of crystallization inhibitors...
  38. ncbi request reprint Sialolithiasis: mechanism of calculi formation and etiologic factors
    Felix Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University of Balearic Islands, 07071, Palma de Mallorca, Spain
    Clin Chim Acta 334:131-6. 2003
    ..Sialolithiasis is a common disease of salivary glands. The etiology of these calculi is little known and their exact mechanism of formation is unknown...
  39. ncbi request reprint Papillary and nonpapillary calcium oxalate monohydrate renal calculi: comparative study of etiologic factors
    Enrique Pieras
    University Hospital Son Dureta, Palma de Mallorca, Spain
    ScientificWorldJournal 6:2411-9. 2006
    ....
  40. ncbi request reprint Factors affecting the regrowth of renal stones in vitro: a contribution to the understanding of renal stone development
    Antonia Costa-Bauza
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University of the Balearic Islands, Palma de Mallorca, Spain
    Scand J Urol Nephrol 39:194-9. 2005
    ....
  41. doi request reprint Risk factors for urinary stones in healthy schoolchildren with and without a family history of nephrolithiasis
    Concepción Sáez-Torres
    Universitary Institute of Health Sciences Research IUNICS, University of Balearic Islands, Carretera de Valldemossa Km 7 5, 07122, Palma de Mallorca, Spain
    Pediatr Nephrol 28:639-45. 2013
    ..The prevalence of lithiasis is increasing at all ages. This study aimed to assess the crystallization risk in urine from healthy school children and to determine urinary parameters that are most associated with it...
  42. ncbi request reprint Simple classification of renal calculi closely related to their micromorphology and etiology
    Felix Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University of Balearic Islands, Ctra Valldemossa km 7 5, 07071 Palma de Mallorca, Spain
    Clin Chim Acta 322:29-36. 2002
    ..Classification of renal calculi with clear correlation with the main urinary etiological conditions has been previously established. However, such information is complex and difficult to adapt to clinical routine practice...
  43. doi request reprint Effects of short and long-term indapamide treatments on urinary calcium excretion in patients with calcium oxalate dihydrate urinary stone disease: a pilot study
    Diego Alonso
    University Hospital Son Espases, Palma de Mallorca, Spain
    Scand J Urol Nephrol 46:97-101. 2012
    ..The aim of this study was to determine the relative calcium-reducing effects of indapamide at 6 and 18 months using a dose of 1.5 mg/day...
  44. ncbi request reprint Synergism between the brushite and hydroxyapatite urinary crystallization inhibitors
    Antonia Costa-Bauza
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University of Illes Balears 07071, Palma de Mallorca, Spain
    Int Urol Nephrol 34:447-51. 2002
    ....
  45. ncbi request reprint Determination of uric acid in urine, saliva and calcium oxalate renal calculi by high-performance liquid chromatography/mass spectrometry
    Joan Perello
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, Universitary Institute of Health Sciences Research IUNICS, University of Balearic Islands, Ctra Valldemossa, km 7 5, 07122 Palma of Mallorca, Spain
    J Chromatogr B Analyt Technol Biomed Life Sci 824:175-80. 2005
    ..The method has been also applied to the determination of trace amounts of uric acid in the core of some selected calcium oxalate renal calculi...
  46. doi request reprint Protective effect of myo-inositol hexaphosphate (phytate) on bone mass loss in postmenopausal women
    Ángel A López-González
    Servicio de Prevención de Riesgos Laborales de GESMA Gestión Sanitaria de Mallorca, Palma de Mallorca, Spain
    Eur J Nutr 52:717-26. 2013
    ..The objective of this paper was to evaluate the relationship between urinary concentrations of InsP6, bone mass loss and risk fracture in postmenopausal women...
  47. ncbi request reprint Type of renal calculi: variation with age and sex
    Antonia Costa-Bauza
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, Universitary Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122 Palma de Mallorca, Spain
    World J Urol 25:415-21. 2007
    ....
  48. ncbi request reprint Effects of escin on indinavir crystallization time in the urine of patients with HIV-I infection: a multicenter, randomized, open-label, controlled, four-period crossover trial
    Felix Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University of the Balearic Islands, Ctra Valldemossa, km 7 5, 07122 Palma de Mallorca, Spain
    Clin Ther 26:2045-55. 2004
    ..An in vitro study has shown that addition of escin to synthetic urine containing indinavir delayed the crystallization time of indinavir...
  49. ncbi request reprint Effects of phytate and pyrophosphate on brushite and hydroxyapatite crystallization. Comparison with the action of other polyphosphates
    F Grases
    Laboratory of Urolithiasis Research, Faculty of Sciences, University of Illes Balears, Palma de Mallorca, Spain
    Urol Res 28:136-40. 2000
    ..87x10(-6) M prevented crystallization during time periods of at least 1 h). This demonstrates that low excretion of these substances would pose a risk of renal lithiasis...
  50. doi request reprint Urinary lithogenesis risk tests: comparison of a commercial kit and a laboratory prototype test
    Felix Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research, University of Balearic Islands, Palma de Mallorca, Spain
    Scand J Urol Nephrol 45:312-8. 2011
    ..The objective of this study was to compare data obtained using a commercial kit with those of a laboratory prototype, using a multicentre approach, to validate the utility of these methods in routine clinical practice...
  51. ncbi request reprint Determination of pyrophosphate in renal calculi and urine by means of an enzymatic method
    J G March
    Department of Chemistry, University of Balearic Islands, Campus de la UIB, Ctra Valldemossa km 7 5, E 07071 Palma de Mallorca, Spain
    Clin Chim Acta 314:187-94. 2001
    ..For urinary pyrophosphate determination, a modification based on a clean-up of urine using activated carbon has been proposed. Pyrophosphate in human urine was of the order of 4 mg l(-1)...
  52. ncbi request reprint An experimental study on residual lithiasis after shock wave lithotripsy
    A Costa-Bauza
    Laboratory of Renal Lithiasis Research, Institute of Health Sciences Research IUNICS, University of Balearic Islands 07122 Palma of Mallorca, Spain
    Urol Res 33:51-6. 2005
    ..The in vitro regrowth of post-ESWL COM fragments was clearly influenced by the presence of crystallization inhibitors. These data also demonstrate the importance that effective prophylactic therapies could exert on preventing recurrence...
  53. ncbi request reprint Phytate prevents tissue calcifications in female rats
    F Grases
    Laboratory of Renal Lithiasis Research, University of Balearic Islands, Palma de Mallorca, Spain
    Biofactors 11:171-7. 2000
    ..Only rats of the AIN-76 A group displayed mineral deposits at the corticomedullary junction. These findings demonstrated that the absence of phytate in the AIN-76 A diet is one of the causes of renal calcification in female rats...
  54. ncbi request reprint Urinary phytate in calcium oxalate stone formers and healthy people--dietary effects on phytate excretion
    F Grases
    Laboratory of Renal Lithiasis Research, University of Balearic Islands, Palma de Mallorca, Spain
    Scand J Urol Nephrol 34:162-4. 2000
    ..This demonstrated the importance of dietary phytate in maintaining adequate urinary levels to permit effective crystallization inhibition of calcium salts and consequently preventing renal stone development...
  55. doi request reprint Effects of Mediterranean diets with low and high proportions of phytate-rich foods on the urinary phytate excretion
    Rafael M Prieto
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122 Palma, Spain
    Eur J Nutr 49:321-6. 2010
    ..This includes the prevention of pathological calcifications such as renal calculi, dental calculi and cardiovascular calcification, due its action as crystallization inhibitor of calcium salts, and as preventive of cancer...
  56. ncbi request reprint Dietary phytate and mineral bioavailability
    F Grases
    Laboratory of Renal Lithiasis Research, University of Balearic Islands, Palma de Mallorca, Spain
    J Trace Elem Med Biol 15:221-8. 2001
    ....
  57. ncbi request reprint Phytate levels in diverse rat tissues: influence of dietary phytate
    F Grases
    Laboratory of Renal Lithiasis Research, University of Balearic Islands, Palma de Mallorca, Spain
    Br J Nutr 86:225-31. 2001
    ..Consequently, considering that InsP6 could be involved in some important biological roles, the value of any diet on supplying this substance is noteworthy...
  58. ncbi request reprint Urinary excretion of calcium, magnesium, phosphate, citrate, oxalate, and uric acid by healthy schoolchildren using a 12-h collection protocol
    Concepción Sáez-Torres
    University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Carretera de Valldemossa Km 7 5, 07122, Palma de Mallorca, Spain
    Pediatr Nephrol 29:1201-8. 2014
    ....
  59. doi request reprint Analysis of spontaneously passed urinary tract stones
    Daniel Muñoz-Velez
    Department of Urology, University Hospital Son Dureta, C Andrea Doria, 55, 07013, Palma de Mallorca, Spain
    Urol Res 38:35-9. 2010
    ..These findings are also found to be similar to those reported in previous studies examining both spontaneously and non-spontaneously passed stones...
  60. ncbi request reprint Inositol hexakisphosphate in urine: the relationship between oral intake and urinary excretion
    F Grases
    Laboratory of Renal Lithiasis Research, University of the Belearic Islands, Palma de Mallorca, Spain
    BJU Int 85:138-42. 2000
    ..To study the relationship between the oral intake of inositol hexakisphosphate (InsP6, phytic acid, an inhibitor of urinary crystallization) and its urinary excretion, to establish their possible mutual influence...
  61. ncbi request reprint Determination of phosphate in urine by sequential injection analysis
    B M Simonet
    Department of Chemistry, University of Balearic Islands, 07071 Palma de Mallorca, Spain
    Fresenius J Anal Chem 369:96-102. 2001
    ..This interference was solved using a cation exchange resin as a part of the manifold. Considering the low toxicity of used reagents, these methods can be considered as a contribution to Green Analytical Chemistry...
  62. ncbi request reprint Enzymatic determination of pyrophosphate in urine by flow methods
    Bartolome M Simonet
    Department of Chemistry, University of Balearic Islands, E 07071 Palma de Mallorca, Spain
    Anal Sci 19:1029-32. 2003
    ..29 mg L(-1), and CV of 2.2% for the open-close circuit method. The methods were applied to the determination of pyrophosphate in urine. The pyrophosphate concentration determined in urine samples varied from 1.26 to 6.67 mg L(-1)...
  63. ncbi request reprint Anxiety and stress among science students. Study of calcium and magnesium alterations
    G Grases
    University of Balearic Islands, Dept Applied Pedagogy and Educational Psychology, Palma of Mallorca, Spain
    Magnes Res 19:102-6. 2006
    ..Nevertheless, stress also correlates with a urinary calcium increase which was not detected in the present study...
  64. ncbi request reprint Uric acid calculi: types, etiology and mechanisms of formation
    F Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University of Illes Balears, Ctra Valldemossa km 7 5, 07071, Palma de Mallorca, Spain
    Clin Chim Acta 302:89-104. 2000
    ....
  65. ncbi request reprint Uric acid urolithiasis and crystallization inhibitors
    F Grases
    Laboratory of Urolithiasis Research, Faculty of Sciences, University of Illes Balears, Palma de Mallorca, Spain
    Urol Int 62:201-4. 1999
    ..From the results obtained it can be deduced that mainly glycoproteins, glycosaminoglycans and surfactant substances can exert protective effects against uric acid crystallization...
  66. ncbi request reprint Study on concretions developed around urinary catheters and mechanisms of renal calculi development
    F Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University Illes Balears, Palma de Mallorca, Spain
    Nephron 88:320-8. 2001
    ..To study the structure and composition of encrustation and concretions developed on urinary catheters to better understand their formation mechanism to be able to prevent them...
  67. ncbi request reprint Absorption and excretion of orally administered inositol hexaphosphate (IP(6) or phytate) in humans
    F Grases
    Laboratory of Renal Lithiasis Research, Faculty of Science, University of Illes Balears, 07071 Palma de Mallorca, Spain
    Biofactors 15:53-61. 2001
    ..Thus, the normal plasma and urinary concentrations, can be obtained either by consumption of a IP(6)ND taking a long time or in a short period by IP(6) supplements...
  68. ncbi request reprint Kinetic versus thermodynamic factors in calcium renal lithiasis
    F Grases
    Laboratory of Renal Lithiasis Research, University of Illes Balears, Palma de Mallorca, Spain
    Int Urol Nephrol 32:19-27. 2000
    ..The results of this evaluation were used to assess the possible effectiveness of a given pharmacological treatment...
  69. ncbi request reprint Phytate (myo-inositol hexaphosphate) and risk factors for osteoporosis
    A A López-González
    Servicio de Prevencion de Riesgos Laborales, Gestion Sanitaria de Mallorca, Palma de Mallorca, Spain
    J Med Food 11:747-52. 2008
    ..Phytate consumption had a protective effect against osteoporosis, suggesting that low phytate consumption should be considered an osteoporosis risk factor...
  70. ncbi request reprint Determination of phytic acid by gas chromatography-mass spectroscopy: application to biological samples
    J G March
    Department of Chemistry, University of Balearic Islands, Palma de Mallorca, Spain
    J Chromatogr B Biomed Sci Appl 757:247-55. 2001
    ..Phytic acid amounts found in rat organs ranged from 1.07 g kg(-1) for bone to 32.0 g kg(-1) for brain. Phytic acid in human plasma was of the order of 0.14 mg l(-1). In kidney stones, phytic acid was found in calcium containing stones...