Jose L Domingo

Summary

Affiliation: Universitat Rovira i Virgili
Country: Spain

Publications

  1. ncbi request reprint Exposure to PBDEs and PCDEs associated with the consumption of edible marine species
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Environ Sci Technol 40:4394-9. 2006
  2. ncbi request reprint Aluminum, restraint stress and aging: behavioral effects in rats after 1 and 2 years of aluminum exposure
    Jose L Roig
    Department of Psychology, Psychobiology Unit, Rovira i Virgili University, Sescelades Campus, 43007 Tarragona, Spain
    Toxicology 218:112-24. 2006
  3. ncbi request reprint Aluminum and other metals in Alzheimer's disease: a review of potential therapy with chelating agents
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, 43201 Reus, Spain
    J Alzheimers Dis 10:331-41. 2006
  4. ncbi request reprint Polychlorinated diphenyl ethers (PCDEs): environmental levels, toxicity and human exposure: a review of the published literature
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, Reus, Spain
    Environ Int 32:121-7. 2006
  5. doi request reprint Effects of exposure to BDE-99 on oxidative status of liver and kidney in adult rats
    Maria L Albina
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorens 21, 43201 Reus, Catalonia, Spain
    Toxicology 271:51-6. 2010
  6. ncbi request reprint Pro-oxidant activity of aluminum in the rat hippocampus: gene expression of antioxidant enzymes after melatonin administration
    Mercedes Gomez
    Laboratory of Toxicology and Environmental Health, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Free Radic Biol Med 38:104-11. 2005
  7. doi request reprint Concentrations of metals in soils in the neighborhood of a hazardous waste incinerator: assessment of the temporal trends
    Lolita Vilavert
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Biol Trace Elem Res 149:435-42. 2012
  8. ncbi request reprint Body burden monitoring of dioxins and other organic substances in workers at a hazardous waste incinerator
    Montse Mari
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Catalonia, Spain Environmental Engineering Laboratory, Departament d Enginyeria Quimica, Universitat Rovira i Virgili, Av Paisos Catalans 26, 43007 Tarragona, Catalonia, Spain
    Int J Hyg Environ Health 216:728-34. 2013
  9. ncbi request reprint Exposure of pregnant rats to uranium and restraint stress: effects on postnatal development and behavior of the offspring
    Domenec J Sanchez
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Toxicology 228:323-32. 2006
  10. ncbi request reprint Intake of chemical contaminants through fish and seafood consumption by children of Catalonia, Spain: health risks
    Roser Martí-Cid
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Food Chem Toxicol 45:1968-74. 2007

Collaborators

Detail Information

Publications89

  1. ncbi request reprint Exposure to PBDEs and PCDEs associated with the consumption of edible marine species
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Environ Sci Technol 40:4394-9. 2006
    ..With respectto PCDE congeners, to establish TEF values would be of great value to evaluate human health risks...
  2. ncbi request reprint Aluminum, restraint stress and aging: behavioral effects in rats after 1 and 2 years of aluminum exposure
    Jose L Roig
    Department of Psychology, Psychobiology Unit, Rovira i Virgili University, Sescelades Campus, 43007 Tarragona, Spain
    Toxicology 218:112-24. 2006
    ..Interestingly, while prenatal restraint stress did not modify behavioral parameters, Al accumulation was prevented by prenatal restraint...
  3. ncbi request reprint Aluminum and other metals in Alzheimer's disease: a review of potential therapy with chelating agents
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, 43201 Reus, Spain
    J Alzheimers Dis 10:331-41. 2006
    ..Finally, the potential role of silicon in AD is also discussed...
  4. ncbi request reprint Polychlorinated diphenyl ethers (PCDEs): environmental levels, toxicity and human exposure: a review of the published literature
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, Reus, Spain
    Environ Int 32:121-7. 2006
    ..However, data concerning PCDE levels in foodstuffs are very limited. It is concluded that investigations on experimental toxicity, dietary intake, and potential human health effects of PCDEs are clearly necessary...
  5. doi request reprint Effects of exposure to BDE-99 on oxidative status of liver and kidney in adult rats
    Maria L Albina
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorens 21, 43201 Reus, Catalonia, Spain
    Toxicology 271:51-6. 2010
    ..The results of this investigation suggest that acute oral BDE-99 exposure causes renal and liver impairment, being oxidative damage a potential mechanism for nephrotoxicity and hepatotoxicity...
  6. ncbi request reprint Pro-oxidant activity of aluminum in the rat hippocampus: gene expression of antioxidant enzymes after melatonin administration
    Mercedes Gomez
    Laboratory of Toxicology and Environmental Health, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Free Radic Biol Med 38:104-11. 2005
    ....
  7. doi request reprint Concentrations of metals in soils in the neighborhood of a hazardous waste incinerator: assessment of the temporal trends
    Lolita Vilavert
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Biol Trace Elem Res 149:435-42. 2012
    ..The estimated carcinogenic and noncarcinogenic risks derived from exposure to these metals from soils should not mean any special concern for the population living in the surroundings of the HWI...
  8. ncbi request reprint Body burden monitoring of dioxins and other organic substances in workers at a hazardous waste incinerator
    Montse Mari
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Catalonia, Spain Environmental Engineering Laboratory, Departament d Enginyeria Quimica, Universitat Rovira i Virgili, Av Paisos Catalans 26, 43007 Tarragona, Catalonia, Spain
    Int J Hyg Environ Health 216:728-34. 2013
    ..Consequently, general conclusions cannot be derived and the results should not be used as a basis for the implementation of industrial hygiene measures in other HWIs. ..
  9. ncbi request reprint Exposure of pregnant rats to uranium and restraint stress: effects on postnatal development and behavior of the offspring
    Domenec J Sanchez
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Toxicology 228:323-32. 2006
    ..The influence of stress was very limited...
  10. ncbi request reprint Intake of chemical contaminants through fish and seafood consumption by children of Catalonia, Spain: health risks
    Roser Martí-Cid
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Food Chem Toxicol 45:1968-74. 2007
    ..In relation to body weight, intake by children of most contaminants was higher than that found for other age groups of the general population of Catalonia...
  11. ncbi request reprint Levels of chemical and microbiological pollutants in the vicinity of a waste incineration plant and human health risks: temporal trends
    Lolita Vilavert
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Chemosphere 84:1476-83. 2011
    ..On the other hand, the concentrations of VOCs (mean range: 7.6-18.2 μg m(-3)) were typical of suburban zones. The current exposure to those compounds should not mean additional health risks for the population living nearby...
  12. doi request reprint Multi-compartmental environmental surveillance of a petrochemical area: levels of micropollutants
    Marti Nadal
    Laboratory of Toxicology and Environmental Health, Rovira i Virgili University, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Environ Int 35:227-35. 2009
    ..In air, the higher amount of the 7 carcinogenic PAHs suggests a relatively greater impact on the petrochemical and urban areas. The temporal trend of the global pollution was also studied an Integral Risk Index was applied...
  13. ncbi request reprint Benefits and risks of fish consumption Part I. A quantitative analysis of the intake of omega-3 fatty acids and chemical contaminants
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Toxicology 230:219-26. 2007
    ..However, the type of fish, the frequency of consumption, and the meal size are essential issues for the balance of the health benefits and risks of regular fish consumption...
  14. doi request reprint Levels of metals and organic substances in workers at a hazardous waste incinerator: a follow-up study
    Montse Mari
    Department of Chemical Engineering, School of Chemical Engineering, Rovira i Virgili University, Sescelades Campus, Tarragona, Spain
    Int Arch Occup Environ Health 82:519-28. 2009
    ..To compare these concentrations with the baseline (1999) levels and with those obtained in previous (2000 and 2005) surveys...
  15. doi request reprint Protective role of melatonin on oxidative stress status and RNA expression in cerebral cortex and cerebellum of AbetaPP transgenic mice after chronic exposure to aluminum
    Tania Garcia
    Laboratory of Toxicology and Environmental Health, IISPV, School of Medicine, Rovira i Virgili University, Sant Llorens 21, 43201 Reus, Catalonia, Spain
    Biol Trace Elem Res 135:220-32. 2010
    ..Melatonin exerted an antioxidant action by increasing the mRNA levels of the enzymes SOD1, CAT, and GR evaluated in presence of Al and Mel, independently on the animal model...
  16. doi request reprint Behavioral effects and oxidative status in brain regions of adult rats exposed to BDE-99
    Montserrat Belles
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV Universitat Rovira i Virgili, Sant Llorens 21, 43201 Reus, Catalonia, Spain
    Toxicol Lett 194:1-7. 2010
    ..The current results show that the brain antioxidant capacity is affected by BDE-99 exposure, mainly in cerebellum. Oxidative damage could be a mechanism for BDE-99 neurotoxicity in adult rats...
  17. doi request reprint Partial replacement of fossil fuel in a cement plant: risk assessment for the population living in the neighborhood
    Joaquim Rovira
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Sci Total Environ 408:5372-80. 2010
    ..However, further long-term environmental studies are necessary to corroborate the harmlessness of RDF, in terms of human health risks...
  18. ncbi request reprint Environmental monitoring of metals, PCDD/Fs and PCBs as a complementary tool of biological surveillance to assess human health risks
    Joaquim Rovira
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Chemosphere 80:1183-9. 2010
    ....
  19. ncbi request reprint Monitoring metals in the population living in the vicinity of a hazardous waste incinerator: levels in hair of school children
    Marti Nadal
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Biol Trace Elem Res 104:203-13. 2005
    ..In general terms, the current metal levels in hair of school children are similar or even lower than those recently reported for a number of industrial and residential areas of various regions and countries...
  20. ncbi request reprint Long-term monitoring of dioxins and furans near a municipal solid waste incinerator: human health risks
    Lolita Vilavert
    Laboratory of Toxicology and Environmental Health, IISPV, Universitat Rovira i Virgili, Reus, Catalonia, Spain
    Waste Manag Res 30:908-16. 2012
    ..The current results clearly show that the MSWI of Tarragona does not produce additional health risks for the population living nearby...
  21. ncbi request reprint Concurrent exposure to aluminum and stress during pregnancy in rats: Effects on postnatal development and behavior of the offspring
    M Teresa Colomina
    Department of Psychology, Psychobiology Unit, Rovira i Virgili University, Sescelades Campus, 43007 Tarragona, Spain
    Neurotoxicol Teratol 27:565-74. 2005
    ..In general terms, the results of the present study did not show a notable influence of maternal restraint on the Al-induced postnatal developmental and behavioral effects in the offspring of prenatally Al-exposed rats...
  22. doi request reprint Use of sewage sludge as secondary fuel in a cement plant: human health risks
    Joaquim Rovira
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Environ Int 37:105-11. 2011
    ....
  23. ncbi request reprint Health risk assessment of emissions of dioxins and furans from a municipal waste incinerator: comparison with other emission sources
    Montse Meneses
    Environmental Engineering Laboratory, Department of Chemical Engineering, Rovira i Virgili University, 43007 Tarragona, Spain
    Environ Int 30:481-9. 2004
    ..16 to 0.38. The above data show that other emission sources of PCDD/Fs also have a notable environmental impact on the area under direct influence of the MSWI...
  24. ncbi request reprint Restraint stress does not enhance the uranium-induced developmental and behavioral effects in the offspring of uranium-exposed male rats
    M Luisa Albina
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Toxicology 215:69-79. 2005
    ..It is concluded that at the current U doses, restraint stress did not enhance the few uranium-induced physical, neuromotor and behavioral changes in the offspring of UAD-exposed male rats...
  25. ncbi request reprint Human exposure to dioxins and furans: application of the substance flow analysis to health risk assessment
    Gerard Fuster
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, Reus, Spain
    Environ Sci Pollut Res Int 9:241-9. 2002
    ..7% reduction in the PCDD/F accumulation in humans. In turn, a 100% reduction of PCDD/Fs in the industrial waste waters would cause only an insignificant 0.1% decrease in the accumulation of PCDD/Fs in humans...
  26. ncbi request reprint Human dietary exposure to perfluoroalkyl substances in Catalonia, Spain. Temporal trend
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Spain
    Food Chem 135:1575-82. 2012
    ..In general terms, PFAS levels found in the current study are lower than the concentrations recently reported in other countries...
  27. doi request reprint Oxidative stress status and RNA expression in hippocampus of an animal model of Alzheimer's disease after chronic exposure to aluminum
    Tania Garcia
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Rovira i Virgili University, Sant Llorenc 21, Reus, Catalonia, Spain
    Hippocampus 20:218-25. 2010
    ..Melatonin exerts an antioxidant action by increasing the mRNA levels of the antioxidant enzymes SOD, CAT, and GR evaluated in presence of Al and Mel, with independence of the animal model...
  28. doi request reprint Monitoring environmental pollutants in the vicinity of a cement plant: a temporal study
    Joaquim Rovira
    Universitat Rovira i Virgili, Reus, Catalonia, Spain
    Arch Environ Contam Toxicol 60:372-84. 2011
    ..Despite this, the carcinogenic and noncarcinogenic risks derived from human exposure to metals and PCDD/Fs were within the ranges considered acceptable by international regulatory organisms...
  29. doi request reprint Environmental versus dietary exposure to POPs and metals: a probabilistic assessment of human health risks
    Victoria Linares
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Rovira i Virgili University, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    J Environ Monit 12:681-8. 2010
    ..Notwithstanding, in order to consider the synergistic/antagonistic effects according to the target organ or mode-of-action, the development of alternative methodologies of risk assessment are necessary for a more accurate evaluation...
  30. doi request reprint Modification of an environmental surveillance program to monitor PCDD/Fs and metals around a municipal solid waste incinerator
    Lolita Vilavert
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Rovira i Virgili University, Reus, Catalonia, Spain
    J Environ Sci Health A Tox Hazard Subst Environ Eng 44:1343-52. 2009
    ..This indicates that the environmental impact of the MSWI of Tarragona is not significant. Moreover, the modification of the surveillance program has proven to be successful...
  31. doi request reprint Exposure to heavy metals and PCDD/Fs by the population living in the vicinity of a hazardous waste landfill in Catalonia, Spain: health risk assessment
    Montse Mari
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Rovira i Virgili University, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Environ Int 35:1034-9. 2009
    ..Anyhow, the current concentrations of metals and PCDD/Fs suggest that it is highly unlikely that there are any additional non-carcinogenic and carcinogenic risks for the population living near the HWL...
  32. doi request reprint Health risks of the occupational exposure to microbiological and chemical pollutants in a municipal waste organic fraction treatment plant
    Marti Nadal
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Rovira i Virgili University, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Int J Hyg Environ Health 212:661-9. 2009
    ..The results of this study can be useful to elaborate occupational risk prevention programs for workers in composting plants...
  33. ncbi request reprint Motor and anxiety effects of PNU-282987, an alpha7 nicotinic receptor agonist, and stress in an animal model of Alzheimer's disease
    Paloma Vicens
    Department of Psychology, Universitat Rovira i Virgili, 43007 Tarragona, Spain
    Curr Alzheimer Res 10:516-23. 2013
    ..009) on anxiety evaluated in an open field depending on genetic vulnerability. Moreover, PNU seems to reverse stress effects in the same apparatus. This was also observed when a more sensitive task such as the zero maze was used...
  34. ncbi request reprint Long-term study of environmental levels of dioxins and furans in the vicinity of a municipal solid waste incinerator
    Marta Schuhmacher
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Environ Int 32:397-404. 2006
    ..In turn, human health risks for the population living in the vicinity of the facility after introduction of a modern technology were negligible in comparison with the dietary PCDD/F exposure...
  35. ncbi request reprint Assessment of the pro-oxidant activity of uranium in kidney and testis of rats
    Victoria Linares
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Toxicol Lett 167:152-61. 2006
    ..Although at the current U doses, restraint stress scarcely showed additional adverse effects, its potential influence should not be underrated...
  36. ncbi request reprint Combined action of uranium and stress in the rat. I. Behavioral effects
    Montserrat Belles
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Toxicol Lett 158:176-85. 2005
    ....
  37. doi request reprint Human dietary exposure to uranium in catalonia, Spain
    Montserrat Belles
    Laboratory of Toxicology and Environmental Health and Physiology Unit, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorens 21, 43201 Reus, Catalonia, Spain
    Biol Trace Elem Res 152:1-8. 2013
    ..04 μg/day). Based on the tolerable daily intake established for U, the current dietary intake of this metal by the general population of Catalonia should not mean health risks for any of the different age/gender groups of consumers...
  38. doi request reprint Dietary intake of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) by a population living in the vicinity of a hazardous waste incinerator: assessment of the temporal trend
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Reus, Catalonia, Spain
    Environ Int 50:22-30. 2012
    ..8 pgWHO-TEQ/day. The results of this study show that any increase potentially found in the biological monitoring of the general population living in the area under evaluation should not be attributed to dietary exposure to PCDD/Fs...
  39. ncbi request reprint Environmental monitoring of PCDD/Fs and metals in the vicinity of a cement plant after using sewage sludge as a secondary fuel
    Marta Schuhmacher
    Laboratory of Toxicology and Environmental Health, Rovira i Virgili University, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Chemosphere 74:1502-8. 2009
    ..In conclusion, there were not observed impact changes for the environmental and the local population as a consequence of using sewage sludge as secondary fuel...
  40. ncbi request reprint Human dietary exposure to hexachlorobenzene in Catalonia, Spain
    Roser Martí-Cid
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    J Food Prot 71:2148-52. 2008
    ..All the intakes are considerably lower than the World Health Organization tolerable daily intake, which is 0.17 microg/kg/day for noncancer effects and 0.16 microg/kg/day for neoplastic effects in humans...
  41. ncbi request reprint Behavioral effects in adult mice exposed to perfluorooctane sulfonate (PFOS)
    Silvia Fuentes
    Department of Psychology, Psychobiology Unit, Rovira i Virgili University, Sescelades Campus, 43007, Tarragona, Spain
    Toxicology 242:123-9. 2007
    ..In the retention test, a deleterious effect of PFOS was noted. These results indicate that PFOS exposure induced only slight behavioral effects in adult male mice...
  42. ncbi request reprint Air-vegetation transfer of PCDD/PCDFs: an assessment of field data and implications for modeling
    Marta Schuhmacher
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Environ Pollut 142:143-50. 2006
    ..The results of this investigation can have a potential interest in risk assessment studies and environmental fate models...
  43. doi request reprint Levels of PCDD/Fs, PCBs and PBDEs in breast milk of women living in the vicinity of a hazardous waste incinerator: assessment of the temporal trend
    Marta Schuhmacher
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Catalonia, Spain Environmental Engineering Laboratory, Departament d Enginyeria Quimica, Universitat Rovira i Virgili, Av Paisos Catalans 26, 43007 Tarragona, Catalonia, Spain
    Chemosphere 93:1533-40. 2013
    ..For PCDD/Fs and PCBs, the current decreases are in accordance with the reduction in the dietary intake of these pollutants that we have also observed in recent studies carried out in the same area of study...
  44. ncbi request reprint Melatonin reduces oxidative stress and increases gene expression in the cerebral cortex and cerebellum of aluminum-exposed rats
    José L Esparza
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, Reus, Spain
    J Pineal Res 39:129-36. 2005
    ..The results of the present investigation emphasize the potential use of melatonin as a supplement in the therapy of neurological disorders in which oxidative stress is involved...
  45. ncbi request reprint Probabilistic human health risk of PCDD/F exposure: a socioeconomic assessment
    Marti Nadal
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, Reus, Spain
    J Environ Monit 6:926-31. 2004
    ..In any case, the current levels of PCDD/F exposure would not mean significant carcinogenic and non-carcinogenic risks for the population living in the industrial and residential areas of Tarragona...
  46. doi request reprint Risk assessment of metals from consuming vegetables, fruits and rice grown on soils irrigated with waters of the Ebro River in Catalonia, Spain
    Núria Ferré-Huguet
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, Sant Llorenc 21, 43201, Reus, Catalonia, Spain
    Biol Trace Elem Res 123:66-79. 2008
    ..The intake of the analyzed elements through consumption of the nine selected food items does not mean additional health risks for the consumers of the area...
  47. ncbi request reprint Environmental impact and human health risks of polychlorinated dibenzo-p-dioxins and dibenzofurans in the vicinity of a new hazardous waste incinerator: a case study
    Núria Ferré-Huguet
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Environ Sci Technol 40:61-6. 2006
    ....
  48. doi request reprint Human exposure to perfluorinated compounds in Catalonia, Spain: contribution of drinking water and fish and shellfish
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Spain
    J Agric Food Chem 60:4408-15. 2012
    ..The amounts ingested are well below the recommended tolerable daily intakes, at least for those PFCs for which information is available...
  49. doi request reprint Recognition memory and β-amyloid plaques in adult Tg2576 mice are not modified after oral exposure to aluminum
    Diana Ribes
    Department of Psychology and Research Center for Behavioral Assessment CRAMC, Universitat Rovira i Virgili Sescelades Campus, Tarragona, Catalonia, Spain
    Alzheimer Dis Assoc Disord 26:179-85. 2012
    ..Recognition memory was impaired in Tg2576 mice, whereas β-amyloid plaque depositions were observed in all these animals. However, Al did not alter the recognition memory and β-amyloid plaque loads of Tg2576 mice...
  50. ncbi request reprint Assessment of the temporal trend of the dietary exposure to PCDD/Fs and PCBs in Catalonia, over Spain: health risks
    Gemma Perelló
    Laboratory of Toxicology and Environmental Health, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Catalonia, Spain
    Food Chem Toxicol 50:399-408. 2012
    ..51) and 2006 (1.12pg/kg per day). The current dietary intake of PCDDs plus DL-PCBs is similar or lower than that recently reported in studies performed in a number of regions and countries...
  51. ncbi request reprint Human exposure to arsenic, cadmium, mercury, and lead from foods in Catalonia, Spain: temporal trend
    Isabel Martorell
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorens 21, 43201 Reus, Catalonia, Spain
    Biol Trace Elem Res 142:309-22. 2011
    ..In summary, the results of this study indicate that, currently, the dietary intakes of As, Cd, Hg, and Pb should not mean additional health risks for the consumers...
  52. doi request reprint Volatile organic compounds and bioaerosols in the vicinity of a municipal waste organic fraction treatment plant. Human health risks
    Lolita Vilavert
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Reus, Catalonia, Spain
    Environ Sci Pollut Res Int 19:96-104. 2012
    ..The human health risks due to the presence of those agents were also assessed...
  53. ncbi request reprint Dietary exposure to PCDD/PCDFs by individuals living near a hazardous waste incinerator in Catalonia, Spain: temporal trend
    Roser Martí-Cid
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Chemosphere 70:1588-95. 2008
    ..1 pg I-TEQ/day, when a baseline study was carried out during the construction of the HWI. The present intake is also compared with the dietary intakes of PCDD/PCDFs recently (2006-2007) reported for a number of regions and countries...
  54. ncbi request reprint Influence of maternal restraint stress on the long-lasting effects induced by prenatal exposure to perfluorooctane sulfonate (PFOS) in mice
    Silvia Fuentes
    Department of Psychology, Psychobiology Unit, Rovira i Virgili University, Sescelades Campus, 43007 Tarragona, Spain
    Toxicol Lett 171:162-70. 2007
    ..On the other hand, corticosterone levels were lower in animals prenatally subjected to restraint stress. The current results suggest interactive effects between PFOS and maternal stress...
  55. doi request reprint Influence of cooking processes on the concentrations of toxic metals and various organic environmental pollutants in food: a review of the published literature
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc Reus, Spain
    Crit Rev Food Sci Nutr 51:29-37. 2011
    ..In general terms, cooking procedures that release or remove fat from the product should tend to reduce the total concentrations of the organic contaminants in the cooked food...
  56. ncbi request reprint POP accumulation in the food chain: Integrated risk model for sewage sludge application in agricultural soils
    Ana Passuello
    School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Environ Int 36:577-83. 2010
    ..Air inhalation was noted to be an occupational exposure route of minor importance. Sensitivity analysis for 2,3,7,8TCDD showed that exposure parameters were responsible for most of the variability in the results...
  57. ncbi request reprint Balancing health benefits and chemical risks associated to dietary habits: RIBEFOOD, a new Internet resource
    Roser Martí-Cid
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Toxicology 244:242-8. 2008
    ..RIBEFOOD can be useful not only for professionals (general physicians, nutritionists, endocrinologists, toxicologists, etc.), but also for the general population. It is available at: http://www.fmcs.urv.cat/ribefood/...
  58. ncbi request reprint Levels of polychlorinated biphenyls in foods from Catalonia, Spain: estimated dietary intake
    Juan M Llobet
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    J Food Prot 66:479-84. 2003
    ..56%). The data obtained in this study should be useful in risk assessment with regard to human PCB exposure through food in Catalonia...
  59. ncbi request reprint Evaluation of the protective role of melatonin on the behavioral effects of aluminum in a mouse model of Alzheimer's disease
    Tania Garcia
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Rovira i Virgili University, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Toxicology 265:49-55. 2009
    ..The present results indicate that Tg2576 mice are sensitive to high dietary Al levels. A significant protector role of melatonin on Al-induced behavioral effects was not observed...
  60. doi request reprint Applicability of a neuroprobabilistic integral risk index for the environmental management of polluted areas: a case study
    Marti Nadal
    Laboratory of Toxicology and Environmental Health, Rovira i Virgili University, Reus, Catalonia, Spain
    Risk Anal 28:271-86. 2008
    ..However, the current levels of pollution do not mean a relevant source of health risks for the local population. Moreover, the neuroprobabilistic HI seems to be an adequate tool to be taken into account in risk assessment processes...
  61. ncbi request reprint Air concentrations of PCDD/Fs, PCBs and PCNs using active and passive air samplers
    Montse Mari
    Laboratory of Toxicology and Environmental Health, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Chemosphere 70:1637-43. 2008
    ..Although both particle and gas phase were sorbed by the PUFs, data of gas phase congeners are more reproducible...
  62. ncbi request reprint Human exposure to polychlorinated naphthalenes and polychlorinated diphenyl ethers from foods in Catalonia, Spain: temporal trend
    Roser Martí-Cid
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Environ Sci Technol 42:4195-201. 2008
    ..By contrast, the intake of PCDEs increased to 26%, fish and seafood being the main contributors to this increase...
  63. ncbi request reprint Levels of PCDD/F in adipose tissue on non-occupationally exposed subjects living near a hazardous waste incinerator in Catalonia, Spain
    Marti Nadal
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Catalonia, Spain
    Chemosphere 74:1471-6. 2009
    ..8 vs 11.2 pg WHO-TEQ/g of fat). The increase in the last 5 years would not be directly attributable to exposure to PCDD/F emitted by the HWI, as other biological monitors such as human plasma and milk decreased during the same period...
  64. ncbi request reprint Interactions in developmental toxicology: concurrent exposure to perfluorooctane sulfonate (PFOS) and stress in pregnant mice
    Silvia Fuentes
    Department of Psychology, Psychobiology Unit, Rovira i Virgili University, Sescelades Campus, 43007 Tarragona, Spain
    Toxicol Lett 164:81-9. 2006
    ..5 mg/kg of PFOS and restraint. PFOS-induced adverse effects on maternal and fetal toxicity in mice were observed at lower doses than those previously reported...
  65. ncbi request reprint Human exposure to metals through the diet in Tarragona, Spain: temporal trend
    Ana Bocio
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Biol Trace Elem Res 104:193-201. 2005
    ..For the most toxic elements (As, Cd, Hg, and Pb), it was under their respective Provisional Tolerable Weekly Intake (PTWI) established by the FAO/WHO...
  66. ncbi request reprint Evolution of the dietary exposure to polycyclic aromatic hydrocarbons in Catalonia, Spain
    Roser Martí-Cid
    School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Food Chem Toxicol 46:3163-71. 2008
    ..48 microg/kg), and cereals (20.44 microg/kg). For an average male adult (70-kg body weight), the current dietary intake of the sum of PAHs was higher (12.0 microg/day) than that found in our 2000 survey (8.4 microg/day)...
  67. doi request reprint In vitro tests to assess toxic effects of airborne PM(10) samples. Correlation with metals and chlorinated dioxins and furans
    Neus Roig
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Catalonia, Spain
    Sci Total Environ 443:791-7. 2013
    ..Urban samples from traffic-impacted areas would be significantly more toxic. Finally, environmental temperature was identified as a key parameter, as higher values of ecotoxicity were found in winter...
  68. ncbi request reprint Gestational exposure to BDE-99 produces toxicity through upregulation of CYP isoforms and ROS production in the fetal rat liver
    Jordi Blanco
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, 43201 Reus, Spain
    Toxicol Sci 127:296-302. 2012
    ..Clear signs of embryo/fetal toxicity, due to a possible hormonal disruption, were evidenced by a large increase in the CYP system and the production of reactive oxygen species in fetal liver...
  69. doi request reprint Concentrations of PCDD/PCDFs in plasma of subjects living in the vicinity of a hazardous waste incinerator: follow-up and modeling validation
    Marti Nadal
    Laboratory of Toxicology and Environmental Health, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Catalonia, Spain
    Chemosphere 73:901-6. 2008
    ....
  70. doi request reprint Dietary intake of arsenic, cadmium, mercury, and lead by the population of Catalonia, Spain
    Roser Martí-Cid
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201, Reus, Spain
    Biol Trace Elem Res 125:120-32. 2008
    ..The estimated intakes of As, Cd, Hg, and Pb are notably lower than the respective provisional tolerable weekly intakes, which indicate that these intakes should not mean additional health risks for the consumers...
  71. doi request reprint Effects of various cooking processes on the concentrations of arsenic, cadmium, mercury, and lead in foods
    Gemma Perelló
    Rovira i Virgili University, San Lorenzo, Reus, Spain
    J Agric Food Chem 56:11262-9. 2008
    ..This hypothetical reduction depends upon cooking conditions (time, temperature, and medium of cooking)...
  72. ncbi request reprint Concentrations of PCDD/PCDFs and PCBs in fish and seafood from the Catalan (Spain) market: estimated human intake
    Ana Bocio
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Environ Int 33:170-5. 2007
    ..The results of this study indicate that, in general terms, the dietary habits of the population of Catalonia (Spain) regarding fish and seafood consumption do not contribute remarkably to increase PCDD/F and DL-PCB intake...
  73. doi request reprint Lipid peroxidation and antioxidant status in kidney and liver of rats treated with sulfasalazine
    Victoria Linares
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, Sant Llorens 21, 43201 Reus, Catalonia, Spain
    Toxicology 256:152-6. 2009
    ..These results suggest that in male rats, oxidative damage can be a mechanism for nephro- and hepatotoxicity related with SASP treatment...
  74. ncbi request reprint Human health risks of petroleum-contaminated groundwater
    Eva Lopez
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Environ Sci Pollut Res Int 15:278-88. 2008
    ..Due to industrial activities, accidental petroleum spills are the main route of soil and groundwater contamination. The aim of the present study was to evaluate the indoor health risks due to tap water consumption contaminated by BTEX...
  75. doi request reprint Monitoring temporal trends in environmental levels of polychlorinated dibenzo-p-dioxins and dibenzofurans: results from a 10-year surveillance program of a hazardous waste incinerator
    Lolita Vilavert
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Reus, Catalonia, Spain
    Arch Environ Contam Toxicol 59:521-31. 2010
    ..The results indicated that current concentrations of these contaminants do not pose any additional carcinogenic or noncarcinogenic risk for those people living near the HWI...
  76. ncbi request reprint Polycyclic aromatic hydrocarbons (PAH) in foods and estimated PAH intake by the population of Catalonia, Spain: Temporal trend
    Isabel Martorell
    Laboratory of Toxicology and Environmental Health, Universitat Rovira i Virgili, IISPV, 43201 Reus, Catalonia, Spain
    Environ Int 36:424-32. 2010
    ..72 microg/day, a lower value than those found in our 2000 (8.42 microg/day), and 2006 surveys (12.04 microg/day). With regard to the results of other recent studies, the current PAH concentrations were comparatively lower...
  77. ncbi request reprint Levels of dioxins and furans in plasma of nonoccupationally exposed subjects living near a hazardous waste incinerator
    M Carmen Agramunt
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    J Expo Anal Environ Epidemiol 15:29-34. 2005
    ..It is concluded that emissions from the stack of the HWI assessed here should not mean any additional significant exposure to PCDD/Fs for the population living near the facility...
  78. doi request reprint Levels of metals and PCDD/Fs in the vicinity of a cement plant: assessment of human health risks
    Joaquim Rovira
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Reus, Catalonia, Spain
    J Environ Sci Health A Tox Hazard Subst Environ Eng 46:1075-84. 2011
    ..Risk values for the population living near the facility were similar to those found for residents living in a number of urban and suburban areas...
  79. doi request reprint Combined effects of perfluorooctane sulfonate (PFOS) and maternal restraint stress on hypothalamus adrenal axis (HPA) function in the offspring of mice
    Diana Ribes
    Department of Psychology and Research Center for Behavioral Assessment CRAMC, Rovira i Virgili University, Sescelades Campus, 43007 Tarragona, Catalonia, Spain
    Toxicol Appl Pharmacol 243:13-8. 2010
    ..Interactive effects between PFOS and maternal stress were sex dependent. The current results suggest that prenatal PFOS exposure induced long-lasting effects in mice...
  80. doi request reprint Monitoring PCDD/Fs, PCBs and metals in the ambient air of an industrial area of Catalonia, Spain
    Montse Mari
    Department of Chemical Engineering, ETSEQ, Rovira i Virgili University, Av Paisos Catalans 26, 43007 Tarragona, Spain
    Chemosphere 73:990-8. 2008
    ....
  81. ncbi request reprint Dietary exposure to metals by individuals living near a hazardous waste incinerator in Catalonia, Spain: temporal trend
    Roser Martí-Cid
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Rovira i Virgili University, Sant Llorenc 21, 43201, Reus, Spain
    Biol Trace Elem Res 131:245-54. 2009
    ..The current intake of the most toxic elements (As, Cd, Hg, and Pb) remains under the respective Provisional Tolerable Weekly Intakes established by the Food and Agriculture Organization/World Health Organization...
  82. ncbi request reprint Estimating the environmental impact of micro-pollutants in the low Ebro River (Spain): an approach based on screening toxicity with Vibrio fischeri
    William Ocampo-Duque
    School of Chemical and Process Engineering, Rovira i Virgili University, Tarragona, Spain
    Chemosphere 72:715-21. 2008
    ..Results indicate that Microtox bioassay is an appropriate tool to perform risk assessment studies at screening level...
  83. ncbi request reprint Human exposure to PBDEs through the diet in Catalonia, Spain: temporal trend. A review of recent literature on dietary PBDE intake
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Toxicology 248:25-32. 2008
    ..3 ng/day or 1.4 ng/kg/body weight/day). Finally, the current PBDE intake is compared with the results of recent studies on the dietary intake of PBDEs performed in various European, North American, and Asian countries...
  84. doi request reprint Monitoring metals in blood and hair of the population living near a hazardous waste incinerator: temporal trend
    Núria Ferré-Huguet
    Rovira i Virgili University, Catalonia, Spain
    Biol Trace Elem Res 128:191-9. 2009
    ..In general terms, metal concentrations in hair and blood from subjects living in Tarragona County are lower than most levels reported for other countries in recent years...
  85. doi request reprint Role of deferoxamine on enzymatic stress markers in an animal model of Alzheimer's disease after chronic aluminum exposure
    José L Esparza
    Laboratory of Toxicology and Environmental Health, IISPV, School of Medicine Universitat Rovira i Virgili, Catalonia, Spain
    Biol Trace Elem Res 141:232-45. 2011
    ..Oral Al exposure of AβPP transgenic mice would have some potential to promote pro-oxidant events, while DFO administration would not help in preventing these deleterious effects...
  86. ncbi request reprint Human health risk assessment of environmental exposure to organochlorine compounds in the Catalan stretch of the Ebro River, Spain
    Núria Ferré-Huguet
    Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Rovira i Virgili University, San Lorenzo 21, Reus, Catalonia, Spain
    Bull Environ Contam Toxicol 83:662-7. 2009
    ..In spite of the presence of a chlor-alkali plant located upstream the Ebro River, which could mean a potential source of pollution, the current levels of OCs should not mean significant additional health risks for the local population...
  87. ncbi request reprint Concentrations of PCDD/Fs, PCBs and PBDEs in breast milk of women from Catalonia, Spain: a follow-up study
    Marta Schuhmacher
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, E 43201 Reus, Catalonia, Spain
    Environ Int 35:607-13. 2009
    ..For PCDD/Fs and PCBs, the current decreases are in accordance with the reduction in the dietary intake of these pollutants found in recent studies carried out in the same area of study...
  88. ncbi request reprint Levels of PCDD/PCDFs and PCBs in edible marine species and human intake: a literature review
    Jose L Domingo
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Environ Int 33:397-405. 2007
    ..It is concluded that some groups of population frequently consuming high quantities of certain species could be significantly increasing health risks due to PCDD/F and PCB exposure...
  89. ncbi request reprint Monitoring metals in the population living in the vicinity of a hazardous waste incinerator: concentrations in autopsy tissues
    Ana Bocio
    Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain
    Biol Trace Elem Res 106:41-50. 2005
    ..16 microg/g, 2.11 microg/g, and 0.34 microg/g, respectively). In comparison to the results of the baseline study, a general reduction of most metal concentrations was observed in the current survey...