Juana Diez

Summary

Affiliation: Universitat Pompeu Fabra
Country: Spain

Publications

  1. pmc Metabolite profiling studies in Saccharomyces cerevisiae: an assisting tool to prioritize host targets for antiviral drug screening
    Konstantin Schneider
    Biochemical Engineering Institute, Saarland University, 66123 Saarbrucken, Germany
    Microb Cell Fact 8:12. 2009
  2. pmc Saccharomyces cerevisiae: a versatile eukaryotic system in virology
    Rui P Galao
    Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain
    Microb Cell Fact 6:32. 2007
  3. ncbi request reprint Saccharomyces cerevisiae: a useful model host to study fundamental biology of viral replication
    Isabel Alves-Rodrigues
    Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain
    Virus Res 120:49-56. 2006
  4. pmc Host deadenylation-dependent mRNA decapping factors are required for a key step in brome mosaic virus RNA replication
    Antonio Mas
    Departamento de Ciencias Experimentales y de la Salud, Universitat Pompeu Fabra, Dr Aiguader 80, 08003 Barcelona, Spain
    J Virol 80:246-51. 2006
  5. pmc LSm1-7 complexes bind to specific sites in viral RNA genomes and regulate their translation and replication
    Rui Pedro Galao
    Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain
    RNA 16:817-27. 2010
  6. pmc The cellular decapping activators LSm1, Pat1, and Dhh1 control the ratio of subgenomic to genomic Flock House virus RNAs
    Mireia Gimenez-Barcons
    Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    J Virol 87:6192-200. 2013
  7. pmc Identification of myxobacteria-derived HIV inhibitors by a high-throughput two-step infectivity assay
    Javier P Martínez
    Infection Biology Group, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    Microb Cell Fact 12:85. 2013
  8. pmc Hepatitis C virus infection alters P-body composition but is independent of P-body granules
    Gemma Pérez-Vilaró
    Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    J Virol 86:8740-9. 2012
  9. ncbi request reprint Information catastrophe in RNA viruses through replication thresholds
    Ricard V Sole
    ICREA Complex Systems Lab, Universitat Pompeu Fabra GRIB, Dr Aiguader 80, 08003 Barcelona, Spain
    J Theor Biol 240:353-9. 2006
  10. ncbi request reprint Hepatitis C virus population analysis of a single-source nosocomial outbreak reveals an inverse correlation between viral load and quasispecies complexity
    Antonio Mas
    Departamento de Ciencias Experimentales y de la Salud, Universitat Pompeu Fabra, Dr Aiguader 80, 08003 Barcelona, Spain
    J Gen Virol 85:3619-26. 2004

Collaborators

  • Florenz Sasse
  • Jordi Mestres
  • Josep Sardanyés
  • Ricard V Sole
  • PAUL G AHLQUIST
  • Miguel Bruguera
  • Ashwin Chari
  • Isabel Alves-Rodrigues
  • Mireia Gimenez-Barcons
  • Antonio Mas
  • Andreas Meyerhans
  • Nicoletta Scheller
  • Rui Pedro Galao
  • Javier P Martínez
  • Gemma Pérez-Vilaró
  • Damiá Garriga
  • Utz Fischer
  • Konstantin Schneider
  • Amine Noueiry
  • Rui P Galao
  • Ronald Frank
  • Eric Fleta-Soriano
  • Heinrich Steinmetz
  • Bettina Hinkelmann
  • Jennifer Jungfleisch
  • Rolf Jansen
  • Priscilla M Van Wynsberghe
  • Verónica Saludes
  • Christian Kambach
  • Daniela Lobão
  • Elmar Heinzle
  • Jens Olaf Krömer
  • Christoph Wittmann
  • Leonardo Bruno Mina
  • Tanja Breinig
  • David Andreu
  • Juan Carlos Saiz
  • Baldomero Oliva
  • Ivana Furcic
  • Encarna Ulloa
  • Silvia Fabregas

Detail Information

Publications15

  1. pmc Metabolite profiling studies in Saccharomyces cerevisiae: an assisting tool to prioritize host targets for antiviral drug screening
    Konstantin Schneider
    Biochemical Engineering Institute, Saarland University, 66123 Saarbrucken, Germany
    Microb Cell Fact 8:12. 2009
    ..abstract:..
  2. pmc Saccharomyces cerevisiae: a versatile eukaryotic system in virology
    Rui P Galao
    Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain
    Microb Cell Fact 6:32. 2007
    ....
  3. ncbi request reprint Saccharomyces cerevisiae: a useful model host to study fundamental biology of viral replication
    Isabel Alves-Rodrigues
    Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain
    Virus Res 120:49-56. 2006
    ..Here, we review the different viruses able to direct replication and gene expression in yeast and discuss their main contributions in the understanding of virus biology...
  4. pmc Host deadenylation-dependent mRNA decapping factors are required for a key step in brome mosaic virus RNA replication
    Antonio Mas
    Departamento de Ciencias Experimentales y de la Salud, Universitat Pompeu Fabra, Dr Aiguader 80, 08003 Barcelona, Spain
    J Virol 80:246-51. 2006
    ..Collectively, our results suggest that the Lsm1p-7p/Pat1p/Dhh1p complex that transfers cellular mRNAs from translation to degradation might act as a key regulator in the switch from BMV RNA translation to replication...
  5. pmc LSm1-7 complexes bind to specific sites in viral RNA genomes and regulate their translation and replication
    Rui Pedro Galao
    Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain
    RNA 16:817-27. 2010
    ..Our results provide the first evidence that LSm1-7 complexes interact directly with viral RNA genomes and open new perspectives in the understanding of LSm1-7 functions...
  6. pmc The cellular decapping activators LSm1, Pat1, and Dhh1 control the ratio of subgenomic to genomic Flock House virus RNAs
    Mireia Gimenez-Barcons
    Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    J Virol 87:6192-200. 2013
    ....
  7. pmc Identification of myxobacteria-derived HIV inhibitors by a high-throughput two-step infectivity assay
    Javier P Martínez
    Infection Biology Group, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    Microb Cell Fact 12:85. 2013
    ..Here we established a high-throughput screen based on the highly permissive TZM-bl cell line to identify novel HIV inhibitors. The assay allows discriminating compounds acting on early and/or late steps of the HIV replication cycle...
  8. pmc Hepatitis C virus infection alters P-body composition but is independent of P-body granules
    Gemma Pérez-Vilaró
    Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    J Virol 86:8740-9. 2012
    ..Thus, the HCV-induced changes on P-bodies are mechanistically linked to the function of specific P-body components in HCV RNA translation and replication; however, the formation of P-body granules is not required for HCV infection...
  9. ncbi request reprint Information catastrophe in RNA viruses through replication thresholds
    Ricard V Sole
    ICREA Complex Systems Lab, Universitat Pompeu Fabra GRIB, Dr Aiguader 80, 08003 Barcelona, Spain
    J Theor Biol 240:353-9. 2006
    ..Virol. 85, 3619-3626] can be interpreted through this theoretical view, providing evidence for such a replication threshold. Here a simple model is used in order to provide evidence for such a phenomenon, consistent with available data...
  10. ncbi request reprint Hepatitis C virus population analysis of a single-source nosocomial outbreak reveals an inverse correlation between viral load and quasispecies complexity
    Antonio Mas
    Departamento de Ciencias Experimentales y de la Salud, Universitat Pompeu Fabra, Dr Aiguader 80, 08003 Barcelona, Spain
    J Gen Virol 85:3619-26. 2004
    ..Thus, the relationship between an intrapatient HCV quasispecies and the clinical outcome of an HCV infection is more complex than previously anticipated...
  11. pmc Yeast processing bodies and stress granules: self-assembly ribonucleoprotein particles
    Mireia Gimenez-Barcons
    Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain
    Microb Cell Fact 10:73. 2011
    ..Although the function of PBs and SGs remains elusive, major advances have been done in unraveling their composition and assembly by using the yeast Saccharomyces cerevisae...
  12. ncbi request reprint Modeling the helicase domain of Brome mosaic virus 1a replicase
    Damiá Garriga
    Molecular Immunopathology Unit, Departament de Ciencies Experimentals i de la Salut, Universitat Pompeu Fabra, 08003, Barcelona, Spain
    J Mol Model 10:382-92. 2004
    ..The helicase mechanism was corroborated by the model and this supports the hypothesis that BMV 1a should have helicase activity...
  13. pmc Myxobacteria: natural pharmaceutical factories
    Juana Diez
    Molecular Virology Group, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    Microb Cell Fact 11:52. 2012
    ..Preying mainly on other bacteria and fungi, why would these ancient hunters manufacture compounds beneficial for us? The answer may be the targeting of shared processes and structural features conserved throughout evolution...
  14. pmc Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates
    Nicoletta Scheller
    Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain
    Proc Natl Acad Sci U S A 106:13517-22. 2009
    ....
  15. pmc Xenopus Xp54 and human RCK/p54 helicases functionally replace yeast Dhh1p in brome mosaic virus RNA replication
    Isabel Alves-Rodrigues
    Departamento Ciencias Experimentales y de la Salud, Universitat Pompeu Fabra, Dr Aiguader 80, 08003 Barcelona, Spain
    J Virol 81:4378-80. 2007
    ..This functional conservation, together with the common replication strategies of positive-stranded RNA viruses, suggests that RCK/p54 may also play a role in the replication of positive-stranded RNA viruses that infect humans...