M Cristina de Almagro

Summary

Affiliation: Universitat de Barcelona
Country: Spain

Publications

  1. ncbi UDP-glucuronosyltransferase 1A6 overexpression in breast cancer cells resistant to methotrexate
    M Cristina de Almagro
    Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Av Diagonal 643, E 08028 Barcelona, Spain
    Biochem Pharmacol 81:60-70. 2011
  2. ncbi Overexpression of S100A4 in human cancer cell lines resistant to methotrexate
    Núria Mencia
    Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Barcelona, Spain
    BMC Cancer 10:250. 2010
  3. ncbi Coding polypurine hairpins cause target-induced cell death in breast cancer cells
    M Cristina de Almagro
    Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, E 08028 Barcelona, Spain
    Hum Gene Ther 22:451-63. 2011
  4. ncbi Networking of differentially expressed genes in human cancer cells resistant to methotrexate
    Elisabet Selga
    Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Diagonal Avenue, E 08028 Barcelona, Spain
    Genome Med 1:83. 2009
  5. ncbi Polypurine hairpins directed against the template strand of DNA knock down the expression of mammalian genes
    M Cristina de Almagro
    Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Av Diagonal 643, E 08028 Barcelona, Spain
    J Biol Chem 284:11579-89. 2009

Collaborators

Detail Information

Publications5

  1. ncbi UDP-glucuronosyltransferase 1A6 overexpression in breast cancer cells resistant to methotrexate
    M Cristina de Almagro
    Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Av Diagonal 643, E 08028 Barcelona, Spain
    Biochem Pharmacol 81:60-70. 2011
    ..The pharmacological effect of this induction should be taken into account when combining methotrexate with other drugs that are glucuronidated...
  2. ncbi Overexpression of S100A4 in human cancer cell lines resistant to methotrexate
    Núria Mencia
    Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Barcelona, Spain
    BMC Cancer 10:250. 2010
    ..Combination treatments of MTX with other drugs that could modulate the expression of genes involved in MTX resistance would be an adequate strategy to prevent the development of this resistance...
  3. ncbi Coding polypurine hairpins cause target-induced cell death in breast cancer cells
    M Cristina de Almagro
    Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, E 08028 Barcelona, Spain
    Hum Gene Ther 22:451-63. 2011
    ..Coding-PPRHs can be considered as new molecules to decrease gene expression at the mRNA level and an alternative to other antisense molecules...
  4. ncbi Networking of differentially expressed genes in human cancer cells resistant to methotrexate
    Elisabet Selga
    Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Diagonal Avenue, E 08028 Barcelona, Spain
    Genome Med 1:83. 2009
    ..CONCLUSIONS : Biological association networks identified DKK1, UGT1As and EEF1A1 as important gene nodes in MTX-resistance. Treatments using siRNA technology against these three genes showed chemosensitization toward MTX...
  5. ncbi Polypurine hairpins directed against the template strand of DNA knock down the expression of mammalian genes
    M Cristina de Almagro
    Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Av Diagonal 643, E 08028 Barcelona, Spain
    J Biol Chem 284:11579-89. 2009
    ..Thus, PPRHs can be considered as a new type of molecules to modulate gene expression...