Fernando Simon

Summary

Affiliation: Universidad de Salamanca
Country: Spain

Publications

  1. pmc Canine and human dirofilariosis in the rostov region (southern Russia)
    Vladimir Kartashev
    Rostov State Medical University, Per Nakhichevansky 29, 344022 Rostov na Donu, Russia
    Vet Med Int 2011:685713. 2011
  2. pmc Human and animal dirofilariasis: the emergence of a zoonotic mosaic
    Fernando Simon
    Laboratory of Parasitology, Faculty of Pharmacy and IBSAL, University of Salamanca, Spain
    Clin Microbiol Rev 25:507-44. 2012
  3. ncbi request reprint What is happening outside North America regarding human dirofilariasis?
    F Simon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda Campo Charro s n, 37007 Salamanca, Spain
    Vet Parasitol 133:181-9. 2005
  4. doi request reprint What is new about animal and human dirofilariosis?
    Fernando Simon
    Laboratory of Parasitology, Faculty of Pharmacy, University of Salamanca Avda Campo Charro, s n 37007 Salamanca, Spain
    Trends Parasitol 25:404-9. 2009
  5. doi request reprint Dirofilaria immitis and Wolbachia-derived antigens: its effect on endothelial mammal cells
    F Simon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda del Campo Charro s n, 37007 Salamanca, Spain
    Vet Parasitol 158:223-31. 2008
  6. ncbi request reprint Immunopathology of Dirofilaria immitis infection
    F Simon
    Laboratorio de Parasitologia, Universidad de Salamanca, Salamanca, Spain
    Vet Res Commun 31:161-71. 2007
  7. doi request reprint Geo-environmental model for the prediction of potential transmission risk of Dirofilaria in an area with dry climate and extensive irrigated crops. The case of Spain
    Luis Simon
    Laboratory of Parasitology, Faculty of Pharmacy and IBSAL, University of Salamanca, Salamanca, Spain
    Vet Parasitol 200:257-64. 2014
  8. doi request reprint Identification of immunoreactive proteins of Dirofilaria immitis and D. repens recognized by sera from patients with pulmonary and subcutaneous dirofilariosis
    Javier González-Miguel
    Laboratory of Parasitology, Faculty of Pharmacy, University of Salamanca, Avda Campo Charro s n, Salamanca, Spain
    Parasitol Int 59:248-56. 2010
  9. doi request reprint Identification of Dirofilaria immitis immunoreactive proteins recognized by sera from infected cats using two-dimensional electrophoresis and mass spectrometry
    Javier González-Miguel
    Laboratory of Parasitology, Faculty of Pharmacy, University of Salamanca, Av Campo Charro s n, 37007 Salamanca, Spain
    Mol Biochem Parasitol 174:78-82. 2010
  10. doi request reprint Proteomic analysis of the urine of Dirofilaria immitis infected dogs
    Marta Hormaeche
    Animal and human dirofilariosis group, Laboratory of Parasitology, Institute of Biomedical Research of Salamanca IBSAL, Faculty of Pharmacy, University of Salamanca, 37007 Salamanca, Spain
    Vet Parasitol 203:241-6. 2014

Collaborators

  • Javier González-Miguel
  • Mar Siles-Lucas
  • R Morchon
  • Ana Oleaga
  • G Grandi
  • Vladimir Kartashev
  • Luis Simon
  • Alice Rossi
  • Alexandr Afonin
  • Marta Hormaeche
  • Elena Carretón
  • Jose Alberto Montoya-Alonso
  • Tamara Pavlikovskaya
  • Andrey Vedenkov
  • Olga Sagach
  • Alla Korzan
  • Tatiana Tverdokhlebova
  • Svetlana Nikolaenko
  • Nina Chizh
  • Alvaro Peix
  • Lucía Isabel López-Díez
  • Stefania Gussoni
  • Rosa Sepúlveda
  • Alexey Ermakov
  • Irina Batashova
  • Raisa Pavlova
  • Alexander Klyuchnikov
  • Irina Kolodiy
  • Yulia Levchenko
  • Boris Ilyasov
  • Nicola Pantchev
  • Sergey Kartashov
  • Yulia Kuleshova
  • Elena Ryabikina
  • Marina Babicheva
  • Anna Mironova

Detail Information

Publications22

  1. pmc Canine and human dirofilariosis in the rostov region (southern Russia)
    Vladimir Kartashev
    Rostov State Medical University, Per Nakhichevansky 29, 344022 Rostov na Donu, Russia
    Vet Med Int 2011:685713. 2011
    ..These data show high infection rates of Dirofilaria spp. in both human and dog populations of Rostov, probably because of the existence of favorable conditions for the transmission in this region...
  2. pmc Human and animal dirofilariasis: the emergence of a zoonotic mosaic
    Fernando Simon
    Laboratory of Parasitology, Faculty of Pharmacy and IBSAL, University of Salamanca, Spain
    Clin Microbiol Rev 25:507-44. 2012
    ....
  3. ncbi request reprint What is happening outside North America regarding human dirofilariasis?
    F Simon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda Campo Charro s n, 37007 Salamanca, Spain
    Vet Parasitol 133:181-9. 2005
    ..The causes for the rise in the incidence of human dirofilariasis as well as the possible application of Wolbachia antigens in the serodiagnosis of human infections are discussed...
  4. doi request reprint What is new about animal and human dirofilariosis?
    Fernando Simon
    Laboratory of Parasitology, Faculty of Pharmacy, University of Salamanca Avda Campo Charro, s n 37007 Salamanca, Spain
    Trends Parasitol 25:404-9. 2009
    ....
  5. doi request reprint Dirofilaria immitis and Wolbachia-derived antigens: its effect on endothelial mammal cells
    F Simon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda del Campo Charro s n, 37007 Salamanca, Spain
    Vet Parasitol 158:223-31. 2008
    ..Neither of the two antigens altered the basic physiological mechanisms of endothelial cells, such as cell proliferation, cell cycle, or apoptosis. The biological and pathological significance of these finding are discussed...
  6. ncbi request reprint Immunopathology of Dirofilaria immitis infection
    F Simon
    Laboratorio de Parasitologia, Universidad de Salamanca, Salamanca, Spain
    Vet Res Commun 31:161-71. 2007
    ..This review aims at illustrating current research on the role of both D. immitis and Wolbachia, in the immunology and immunopathology of dirofilariosis...
  7. doi request reprint Geo-environmental model for the prediction of potential transmission risk of Dirofilaria in an area with dry climate and extensive irrigated crops. The case of Spain
    Luis Simon
    Laboratory of Parasitology, Faculty of Pharmacy and IBSAL, University of Salamanca, Salamanca, Spain
    Vet Parasitol 200:257-64. 2014
    ..Moreover, the use of humidity-related factors could be of interest in future predictions to be performed in countries with similar environmental characteristics. ..
  8. doi request reprint Identification of immunoreactive proteins of Dirofilaria immitis and D. repens recognized by sera from patients with pulmonary and subcutaneous dirofilariosis
    Javier González-Miguel
    Laboratory of Parasitology, Faculty of Pharmacy, University of Salamanca, Avda Campo Charro s n, Salamanca, Spain
    Parasitol Int 59:248-56. 2010
    ..repens. This could contribute to explain the differences described in the capacity of D. immitis and D. repens development and in the frequency of occurrence of pulmonary and subcutaneous dirofilariosis in the human host...
  9. doi request reprint Identification of Dirofilaria immitis immunoreactive proteins recognized by sera from infected cats using two-dimensional electrophoresis and mass spectrometry
    Javier González-Miguel
    Laboratory of Parasitology, Faculty of Pharmacy, University of Salamanca, Av Campo Charro s n, 37007 Salamanca, Spain
    Mol Biochem Parasitol 174:78-82. 2010
    ..The real effect on the vital capacity of D. immitis worms and on the development of pathological events of feline dirofilariosis will be investigated in the future...
  10. doi request reprint Proteomic analysis of the urine of Dirofilaria immitis infected dogs
    Marta Hormaeche
    Animal and human dirofilariosis group, Laboratory of Parasitology, Institute of Biomedical Research of Salamanca IBSAL, Faculty of Pharmacy, University of Salamanca, 37007 Salamanca, Spain
    Vet Parasitol 203:241-6. 2014
    ..The loss of these proteins and other in the urine of D. immitis infected dogs could affect the general condition of parasitized dogs through the interference in the cholesterol metabolism and O₂ transport, among other mechanisms...
  11. doi request reprint Surface associated antigens of Dirofilaria immitis adult worms activate the host fibrinolytic system
    Javier González-Miguel
    Laboratory of Parasitology, Faculty of Pharmacy and Institute of Biomedical Research of Salamanca IBSAL, University of Salamanca, 37007 Salamanca, Spain
    Vet Parasitol 196:235-40. 2013
    ..immitis (DiES) and the host fibrinolytic system and many of the molecules identified here are shared by both antigens, we hypothesize that DiSAA cooperate in host fibrinolytic system activation promoting the fibrin clot lysis. ..
  12. doi request reprint Excretory/secretory antigens from Dirofilaria immitis adult worms interact with the host fibrinolytic system involving the vascular endothelium
    Javier González-Miguel
    Laboratory of Parasitology, University of Salamanca, Avda Campo Charro s n, 37007, Salamanca, Spain
    Mol Biochem Parasitol 181:134-40. 2012
    ..The data suggest that DiES antigens interact with the environment of the parasite regulating the activation of the fibrinolytic system of the host with involvement of the vascular endothelium in the process...
  13. doi request reprint Immunoproteomic approach for identification of Ascaris suum proteins recognized by pigs with porcine ascariasis
    Javier González-Miguel
    Laboratory of Parasitology, Faculty of Pharmacy, Institute of Biomedical Research of Salamanca IBSAL and University of Salamanca, 37007 Salamanca, Spain Electronic address
    Vet Parasitol 203:343-8. 2014
    ..These results may aid the search for effective chemo-therapeutic targets in porcine ascariasis. Further studies are needed, however, to illustrate the effect of the host immune response on the survival mechanisms of A. suum. ..
  14. doi request reprint Human subcutaneous/ocular dirofilariasis in the Russian Federation and Belarus, 1997-2013
    Vladimir Kartashev
    Rostov State Medical University, Rostov na Donu, Russia Rostov Research Institute of Microbiology and Parasitology, Rostov na Donu, Russia
    Int J Infect Dis 33:209-11. 2015
    ..This study was performed to determine the yearly frequency, trends in spread, and clinical-epidemiological characteristics of human subcutaneous/ocular dirofilariasis (HSOD) in the Russian Federation and Belarus...
  15. pmc Regional warming and emerging vector-borne zoonotic dirofilariosis in the Russian Federation, Ukraine, and other post-Soviet states from 1981 to 2011 and projection by 2030
    Vladimir Kartashev
    Department of Infectious Diseases, Rostov State Medical University, Nakhichevanskiy Pereulok 29, Rostov na Donu 344022, Russia
    Biomed Res Int 2014:858936. 2014
    ..The results should alert about the epidemiological behavior of dirofilariosis and other mosquito-borne diseases in these and other countries with similar climatic characteristics...
  16. doi request reprint Surface-displayed glyceraldehyde 3-phosphate dehydrogenase and galectin from Dirofilaria immitis enhance the activation of the fibrinolytic system of the host
    Javier González-Miguel
    Faculty of Pharmacy, Laboratory of Parasitology, Institute of Biomedical Research of Salamanca IBSAL, University of Salamanca, 37007 Salamanca, Spain Electronic address
    Acta Trop 145:8-16. 2015
    ....
  17. pmc Can the activation of plasminogen/plasmin system of the host by metabolic products of Dirofilaria immitis participate in heartworm disease endarteritis?
    Javier González-Miguel
    Laboratory of Parasitology, Faculty of Pharmacy, Institute of Biomedical Research of Salamanca IBSAL and University of Salamanca, 37007, Salamanca, Spain
    Parasit Vectors 8:194. 2015
    ..The aim of this study is to relate the appearance of this pathological condition with the activation of the PLG/plasmin system of the host by DiES...
  18. pmc Fibrinolysis and Proliferative Endarteritis: Two Related Processes in Chronic Infections? The Model of the Blood-Borne Pathogen Dirofilaria immitis
    Javier González-Miguel
    Laboratory of Parasitology, Faculty of Pharmacy, Institute of Biomedical Research of Salamanca IBSAL and University of Salamanca, Salamanca, Spain
    PLoS ONE 10:e0124445. 2015
    ..Due to the high degree of evolutionary conservation of these antigens, similar processes may occur in other blood-borne pathogens. ..
  19. doi request reprint Proteomic analysis of Ascaridia galli. Identification of immunoreactive proteins in naturally and experimentally infected hens
    Javier González-Miguel
    Laboratory of Parasitology, Faculty of Pharmacy and Institute of Biomedical Research of Salamanca IBSAL, University of Salamanca, 37007 Salamanca, Spain
    Vet Parasitol 196:388-96. 2013
    ..This work represents the first proteomic study of A. galli and could contribute to explain some aspects of parasite/host relationships of avian ascaridiasis...
  20. ncbi request reprint Haplotype H1 of Culex pipiens implicated as natural vector of Dirofilaria immitis in an endemic area of Western Spain
    Rodrigo Morchon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Salamanca, Spain
    Vector Borne Zoonotic Dis 7:653-8. 2007
    ..The anthropophilic behaviour of this species, and its capture with human bait as attractant, led the authors to speculate that Cx. pipiens could be implicated in the transmission of human dirofilariosis in this endemic area...
  21. doi request reprint Genetic diversity of Dirofilaria spp. isolated from subcutaneous and ocular lesions of human patients in Ukraine
    Alice Rossi
    Instituto de Recursos Naturales y Agrobiologia de Salamanca, Agencia Estatal Consejo Superior de Investigaciones Científicas, Salamanca, Spain
    Acta Trop 142:1-4. 2015
    ..Our results show that ocular dirofilariosis cannot be excluded in areas of low endemicity for D. repens were D. immitis is also present. ..