Research Topics
| Juana Rodríguez FloresSummaryAffiliation: Universidad de Castilla-La Mancha Country: Spain Publications
| Collaborators
|
Detail Information
Publications
Rapid determination of letrozole, citalopram and their metabolites by high performance liquid chromatography-fluorescence detection in urine: Method validation and application to real samplesJ Rodriguez
Department of Analytical Chemistry and Food Technology, University of Castilla La Mancha, 13071 Ciudad Real, Spain Electronic address
J Chromatogr B Analyt Technol Biomed Life Sci 913:12-8. 2013..71%. The accuracy was studied by spiking three urines from healthy female volunteers, and the recoveries were from 85 to 103%. The method was applied to urine samples from women under treatment for breast cancer and depression diseases...
Determination of morphine, codeine, and paclitaxel in human serum and plasma by micellar electrokinetic chromatographyJuana Rodríguez
Department of Analytical Chemistry and Food Technology, University of Castilla La Mancha, Ciudad Real, Spain
J Sep Sci 35:2297-306. 2012..This method was applied to the analysis of serum and plasma samples from different cancer patients undergoing treatment with paclitaxel or/and codeine...
Direct and fast determination of paclitaxel, morphine and codeine in urine by micellar electrokinetic chromatographyJ Rodriguez
Department of Analytical Chemistry and Food Technology, University of Castilla La Mancha, 13071 Ciudad Real, Spain
J Chromatogr A 1231:66-72. 2012..This method was applied to the analysis of six urines samples from different cancer patients undergoing treatment with paclitaxel or/and codeine. In all the urine paclitaxel determination were done...
Rapid quantitative analysis of letrozole, fluoxetine and their metabolites in biological and environmental samples by MEKCJuana Rodríguez-Flores
Department of Analytical Chemistry and Foods Technology, University of Castilla La Mancha, Ciudad Real, Spain
Electrophoresis 30:624-32. 2009..Prior to the determination, the samples were purified and pre-concentrated by means of an extraction-preconcentration step with a C18 cartridge and by eluting the compounds with methanol...
Micellar electrokinetic chromatographic method for the determination of letrozole, citalopram and their metabolites in human urineJ Rodriguez Flores
Department of Analytical Chemistry and Foods Technology, University of Castilla La Mancha, 13071 Ciudad Real, Spain
J Chromatogr A 1185:281-90. 2008..The developed method was applied to the determination of these analytes in three urine samples from patients undergoing treatment with letrozole or citalopram...
Micellar electrokinetic chromatographic screening of letrozole and its metabolite in human urine: validation and robustness/ruggedness evaluationJuana Rodríguez-Flores
Department of Analytical Chemistry and Foods Technology, University of Castilla La Mancha, Ciudad Real, Spain
Electrophoresis 29:811-8. 2008..Real determinations of these analytes in clinical urines of a patient under LE treatment were performed, too...
Capillary electrophoretic determination of triamterene, methotrexate, and creatinine in human urineJuana Rodríguez Flores
Department of Analytical Chemistry and Foods Technology, University of Castilla La Mancha, 13071 Ciudad Real, Spain
J Sep Sci 28:658-64. 2005..The developed method is easy, rapid, and sensitive and has been applied to determine triamterene,methotrexate, and creatinine in urine samples with satisfactory results...
Nonaqueous capillary electrophoresis method for the analysis of gleevec and its main metabolite in human urineJ Rodriguez-Flores
Department of Analytical Chemistry and Foods Technology, University de Castilla La Mancha, Avenida Camilo Jose Cela 10, Ciudad Real 13071, Spain
J Chromatogr A 1068:175-82. 2005..Before NACE determination, a solid-phase extraction (SPE) procedure with a C18 cartridge was necessary. Real determination of these analytes in two patient urines were done...
Capillary electrophoretic determination of methotrexate, leucovorin and folic acid in human urineJ Rodriguez Flores
Department of Analytical Chemistry and Foods Technology, University of Castilla La Mancha, 13071 Ciudad Real, Spain
J Chromatogr B Analyt Technol Biomed Life Sci 819:141-7. 2005..5-6.0 mgL(-1) for folinic acid and folic acid was observed. Detection limits for the three compound in urine were 0.35 mgL(-1). CZE was shown to be a good method with regard to simplicity, satisfactory precision, and sensitivity...
Development of a Micellar electrokinetic capillary chromatography method for the determination of three drugs employed in the erectile dysfunction therapyJ Rodriguez Flores
Department of Analytical Chemistry and Foods Technology, UCLM 13071, Ciudad Real, Spain
J Chromatogr B Analyt Technol Biomed Life Sci 811:231-6. 2004..The described method is rapid, sensitive and rugged and it was tested in the pharmaceutical formulations analysis obtaining recoveries between 98 and 107% respect to the nominal content...
Development of a capillary zone electrophoretic method to determine six antidepressants in their pharmaceutical preparations. Experimental design for evaluating the ruggedness of methodJuana Rodríguez Flores
Department of Analytical Chemistry and Foods Technology, UCLM 13071, Ciudad Real, Spain
J Sep Sci 27:33-40. 2004..The described method is rapid, sensitive, and rugged and it was tested for the pharmaceutical formulation analysis, giving recoveries between 95.6 and 99.1% with respect to the nominal content...
Development and validation method for determination of Paroxetine and its metabolites by nonaqueous capillary electrophoresis in human urine. Experimental design for evaluating the ruggedness of the methodJuana Rodríguez Flores
Department of Analytical Chemistry and Foods Technology, Ciudad Real, Spain
Electrophoresis 25:454-62. 2004..Prior to NACE determination, the samples were purified and enriched by means of an extraction-preconcentration step with a preconditioned C18 cartridge and eluting the compounds with methanol...
Direct and fast capillary zone electrophoretic method for the determination of Gleevec and its main metabolite in human urineJ Rodriguez Flores
Facultad de Quimicas, Universidad de Castilla La Mancha, 13071 Ciudad Real, Spain
J Chromatogr B Analyt Technol Biomed Life Sci 794:381-8. 2003..Detection limits of 0.1 mg l(-1) for Gleevec and its metabolite (S/N=3) were obtained. The developed method is easy, rapid and sensitive and has been applied to determine Gleevec and its main metabolite in clinical urine samples...
