R Morchon

Summary

Affiliation: Universidad de Salamanca
Country: Spain

Publications

  1. ncbi request reprint Proteomic analysis of the somatic and surface compartments from Dirofilaria immitis adult worms
    R Morchon
    Laboratory of Parasitology, Faculty of Pharmacy, University of Salamanca, Avda, Licenciado Méndez Nieto, S N, 37007 Salamanca, Spain Electronic address
    Vet Parasitol 203:144-52. 2014
  2. pmc Heartworm Disease (Dirofilaria immitis) and Their Vectors in Europe - New Distribution Trends
    Rodrigo Morchon
    Group of Dirofilariosis, Faculty of Pharmacy, Institute of Biomedical Research of Salamanca, University of Salamanca Salamanca, Spain
    Front Physiol 3:196. 2012
  3. doi request reprint Zoonotic Dirofilaria immitis infections in a province of Northern Spain
    R Morchon
    Laboratory of Parasitology, Faculty of Pharmacy, University of Salamanca, Salamanca, Spain
    Epidemiol Infect 138:380-3. 2010
  4. ncbi request reprint Feline dirofilariosis: antibody response to antigenic fractions containing specific 20 to 30 kDa polypeptides from the adult Dirofilaria immitis somatic antigen
    G Prieto
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda, Campo Charro s n, 37007 Salamanca, Spain
    Vet Parasitol 103:341-53. 2002
  5. ncbi request reprint Specific IgG antibody response against antigens of Dirofilaria immitis and its Wolbachia endosymbiont bacterium in cats with natural and experimental infections
    R Morchon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Salamanca, Spain
    Vet Parasitol 125:313-21. 2004
  6. ncbi request reprint iNOs expression is stimulated by the major surface protein (rWSP) from Wolbachia bacterial endosymbiont of Dirofilaria immitis following subcutaneous injection in mice
    R Morchon
    Laboratorio de Parasitologia, Universidad de Salamanca, Salamanca, Spain
    Parasitol Int 56:71-5. 2007
  7. doi request reprint Vascular endothelial cell activation by adult Dirofilaria immitis antigens
    R Morchon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda del Campo Charro s n, 37007 Salamanca, Spain
    Parasitol Int 57:441-6. 2008
  8. pmc Immunoglobulin G antibodies against the endosymbionts of filarial nematodes (Wolbachia) in patients with pulmonary dirofilariasis
    F Simon
    Laboratorio di Parassitologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain
    Clin Diagn Lab Immunol 10:180-1. 2003
  9. ncbi request reprint Immunopathology of Dirofilaria immitis infection
    F Simon
    Laboratorio de Parasitologia, Universidad de Salamanca, Salamanca, Spain
    Vet Res Commun 31:161-71. 2007
  10. doi request reprint Dirofilaria immitis and Wolbachia-derived antigens: its effect on endothelial mammal cells
    F Simon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda del Campo Charro s n, 37007 Salamanca, Spain
    Vet Parasitol 158:223-31. 2008

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Proteomic analysis of the somatic and surface compartments from Dirofilaria immitis adult worms
    R Morchon
    Laboratory of Parasitology, Faculty of Pharmacy, University of Salamanca, Avda, Licenciado Méndez Nieto, S N, 37007 Salamanca, Spain Electronic address
    Vet Parasitol 203:144-52. 2014
    ..immitis adult worm, adding new information on protein expression and localization that would facilitate a deeper understanding of the host-parasite relationships in dirofilariosis. ..
  2. pmc Heartworm Disease (Dirofilaria immitis) and Their Vectors in Europe - New Distribution Trends
    Rodrigo Morchon
    Group of Dirofilariosis, Faculty of Pharmacy, Institute of Biomedical Research of Salamanca, University of Salamanca Salamanca, Spain
    Front Physiol 3:196. 2012
    ..Veterinary controls to prevent the spreading of this disease, programs of control of vectors, and adequate protocols of prevention of dirofilariasis in the susceptible species should be carried out...
  3. doi request reprint Zoonotic Dirofilaria immitis infections in a province of Northern Spain
    R Morchon
    Laboratory of Parasitology, Faculty of Pharmacy, University of Salamanca, Salamanca, Spain
    Epidemiol Infect 138:380-3. 2010
    ..The geographic distribution of both canine and human D. immitis infections in La Rioja is restricted to humid and irrigated areas near the Ebro Valley River, being absent in the rest of the province where hills and mountains predominate...
  4. ncbi request reprint Feline dirofilariosis: antibody response to antigenic fractions containing specific 20 to 30 kDa polypeptides from the adult Dirofilaria immitis somatic antigen
    G Prieto
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda, Campo Charro s n, 37007 Salamanca, Spain
    Vet Parasitol 103:341-53. 2002
    ..Both ELISAs were useful in the detection of the decrease of antibodies after the worms were removed by surgery or pharmacological treatment...
  5. ncbi request reprint Specific IgG antibody response against antigens of Dirofilaria immitis and its Wolbachia endosymbiont bacterium in cats with natural and experimental infections
    R Morchon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Salamanca, Spain
    Vet Parasitol 125:313-21. 2004
    ....
  6. ncbi request reprint iNOs expression is stimulated by the major surface protein (rWSP) from Wolbachia bacterial endosymbiont of Dirofilaria immitis following subcutaneous injection in mice
    R Morchon
    Laboratorio de Parasitologia, Universidad de Salamanca, Salamanca, Spain
    Parasitol Int 56:71-5. 2007
    ..This effect is not observed when mice are inoculated with a recombinant heat shock protein from Wolbachia (GroEL)...
  7. doi request reprint Vascular endothelial cell activation by adult Dirofilaria immitis antigens
    R Morchon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda del Campo Charro s n, 37007 Salamanca, Spain
    Parasitol Int 57:441-6. 2008
    ..These results suggest that the somatic extract of D. immitis adult worms stimulate inflammatory mechanisms in endothelial cells, without altering their basic physiologic processes...
  8. pmc Immunoglobulin G antibodies against the endosymbionts of filarial nematodes (Wolbachia) in patients with pulmonary dirofilariasis
    F Simon
    Laboratorio di Parassitologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain
    Clin Diagn Lab Immunol 10:180-1. 2003
    ..immitis was endemic as well as areas in which it was not endemic. Titration of anti-Wolbachia surface protein IgG could become useful for diagnostic applications...
  9. ncbi request reprint Immunopathology of Dirofilaria immitis infection
    F Simon
    Laboratorio de Parasitologia, Universidad de Salamanca, Salamanca, Spain
    Vet Res Commun 31:161-71. 2007
    ..This review aims at illustrating current research on the role of both D. immitis and Wolbachia, in the immunology and immunopathology of dirofilariosis...
  10. doi request reprint Dirofilaria immitis and Wolbachia-derived antigens: its effect on endothelial mammal cells
    F Simon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda del Campo Charro s n, 37007 Salamanca, Spain
    Vet Parasitol 158:223-31. 2008
    ..Neither of the two antigens altered the basic physiological mechanisms of endothelial cells, such as cell proliferation, cell cycle, or apoptosis. The biological and pathological significance of these finding are discussed...
  11. ncbi request reprint Adult Dirofilaria immitis excretory/secretory antigens upregulate the production of prostaglandin E2 and downregulate monocyte transmigration in an "in vitro" model of vascular endothelial cell cultures
    R Morchon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda del Campo Charro s n, 37007 Salamanca, Spain
    Vet Parasitol 170:331-5. 2010
    ....
  12. ncbi request reprint Changes in the levels of eicosanoids in cats naturally and experimentally infected with Dirofilaria immitis
    R Morchon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda Campo Charro s n, 37007 Salamanca, Spain
    Vet Parasitol 147:271-5. 2007
    ....
  13. pmc High levels of serum thromboxane B2 are generated during human pulmonary dirofilariosis
    R Morchon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda Campo Charro s n, 37007, Salamanca, Spain
    Clin Vaccine Immunol 13:1175-6. 2006
    ..The possible role of Wolbachia bacteria in the appearance of this eicosanoid is discussed...
  14. ncbi request reprint What is happening outside North America regarding human dirofilariasis?
    F Simon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda Campo Charro s n, 37007 Salamanca, Spain
    Vet Parasitol 133:181-9. 2005
    ..The causes for the rise in the incidence of human dirofilariasis as well as the possible application of Wolbachia antigens in the serodiagnosis of human infections are discussed...
  15. ncbi request reprint Dogs with patent Dirofilaria immitis infection have higher expression of circulating IL-4, IL-10 and iNOS mRNA than those with occult infection
    R Morchon
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Salamanca, Spain
    Vet Immunol Immunopathol 115:184-8. 2007
    ..These results would suggest that circulating mf may stimulate, like in other filarial infections, an immune bias towards unresponsiveness in D. immitis-infected dogs, consenting long-term adult worm survival...
  16. ncbi request reprint A coprological and serological survey for the prevalence of Ascaridia spp. in laying hens
    J R Martín-Pacho
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Salamanca, Avda Campo Charro s n, 37007 Salamanca, Spain
    J Vet Med B Infect Dis Vet Public Health 52:238-42. 2005
    ..Serological tests are able to detect the infection before the eggs of the parasite appear in the faeces of infected hens, providing a useful tool to detect infections with Ascaridia spp. in avian farms...