Francisco Mora

Summary

Affiliation: Universidad Complutense
Country: Spain

Publications

  1. doi Stress, neurotransmitters, corticosterone and body-brain integration
    Francisco Mora
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Madrid, Spain
    Brain Res 1476:71-85. 2012
  2. ncbi Glutamate-dopamine-GABA interactions in the aging basal ganglia
    Francisco Mora
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, s n 28040 Madrid, Spain
    Brain Res Rev 58:340-53. 2008
  3. ncbi Aging, plasticity and environmental enrichment: structural changes and neurotransmitter dynamics in several areas of the brain
    Francisco Mora
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, 28040 Madrid, Spain
    Brain Res Rev 55:78-88. 2007
  4. doi Blockade of NMDA receptors in the prefrontal cortex increases dopamine and acetylcholine release in the nucleus accumbens and motor activity
    Alberto Del Arco
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Madrid, Spain
    Psychopharmacology (Berl) 201:325-38. 2008
  5. doi Environmental enrichment reduces the response to stress of the cholinergic system in the prefrontal cortex during aging
    Gregorio Segovia
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria s n, 28040 Madrid, Spain
    Neurochem Int 52:1198-203. 2008
  6. doi Prefrontal stimulation of GABAA receptors counteracts the corticolimbic hyperactivity produced by NMDA antagonists in the prefrontal cortex of the rat
    Alberto Del Arco
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Avda Complutense s n, 28040, Madrid, Spain
    Psychopharmacology (Berl) 214:525-36. 2011
  7. ncbi Effects of an enriched environment on the release of dopamine in the prefrontal cortex produced by stress and on working memory during aging in the awake rat
    Gregorio Segovia
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, 28040 Madrid, Spain
    Behav Brain Res 187:304-11. 2008
  8. ncbi Stress, prefrontal cortex and environmental enrichment: studies on dopamine and acetylcholine release and working memory performance in rats
    Alberto Del Arco
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, 28040 Madrid, Spain
    Behav Brain Res 176:267-73. 2007
  9. doi Prefrontal cortex, caloric restriction and stress during aging: studies on dopamine and acetylcholine release, BDNF and working memory
    Alberto Del Arco
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, 28040 Madrid, Spain
    Behav Brain Res 216:136-45. 2011
  10. doi Prefrontal cortex-nucleus accumbens interaction: in vivo modulation by dopamine and glutamate in the prefrontal cortex
    Alberto Del Arco
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Madrid, Spain
    Pharmacol Biochem Behav 90:226-35. 2008

Collaborators

Detail Information

Publications22

  1. doi Stress, neurotransmitters, corticosterone and body-brain integration
    Francisco Mora
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Madrid, Spain
    Brain Res 1476:71-85. 2012
    ..This article is part of a Special Issue entitled: Brain Integration...
  2. ncbi Glutamate-dopamine-GABA interactions in the aging basal ganglia
    Francisco Mora
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, s n 28040 Madrid, Spain
    Brain Res Rev 58:340-53. 2008
    ....
  3. ncbi Aging, plasticity and environmental enrichment: structural changes and neurotransmitter dynamics in several areas of the brain
    Francisco Mora
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, 28040 Madrid, Spain
    Brain Res Rev 55:78-88. 2007
    ....
  4. doi Blockade of NMDA receptors in the prefrontal cortex increases dopamine and acetylcholine release in the nucleus accumbens and motor activity
    Alberto Del Arco
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Madrid, Spain
    Psychopharmacology (Berl) 201:325-38. 2008
    ....
  5. doi Environmental enrichment reduces the response to stress of the cholinergic system in the prefrontal cortex during aging
    Gregorio Segovia
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria s n, 28040 Madrid, Spain
    Neurochem Int 52:1198-203. 2008
    ..EE also decreased motor activity in all groups of age. These results suggest that EE reduces the reactivity to stress of the cholinergic system in the prefrontal cortex during aging...
  6. doi Prefrontal stimulation of GABAA receptors counteracts the corticolimbic hyperactivity produced by NMDA antagonists in the prefrontal cortex of the rat
    Alberto Del Arco
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Avda Complutense s n, 28040, Madrid, Spain
    Psychopharmacology (Berl) 214:525-36. 2011
    ..The hypofunction of NMDA receptors in the prefrontal cortex (PFC) has been suggested to produce corticolimbic hyperactivity through the reduction of cortical GABA transmission...
  7. ncbi Effects of an enriched environment on the release of dopamine in the prefrontal cortex produced by stress and on working memory during aging in the awake rat
    Gregorio Segovia
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, 28040 Madrid, Spain
    Behav Brain Res 187:304-11. 2008
    ..These results suggest that both environmental enrichment and aging reduces the activity of the mesocortical dopamine system...
  8. ncbi Stress, prefrontal cortex and environmental enrichment: studies on dopamine and acetylcholine release and working memory performance in rats
    Alberto Del Arco
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, 28040 Madrid, Spain
    Behav Brain Res 176:267-73. 2007
    ..Spontaneous motor activity in the open field was lower in enriched compared to control animals. These results suggest that environmental enrichment changes acetylcholine, but not dopamine, reactivity to stress in the PFC...
  9. doi Prefrontal cortex, caloric restriction and stress during aging: studies on dopamine and acetylcholine release, BDNF and working memory
    Alberto Del Arco
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, 28040 Madrid, Spain
    Behav Brain Res 216:136-45. 2011
    ..These results suggest that CR does not modify the function of the PFC in response to an acute stress nor the changes found as a result of the normal process of aging...
  10. doi Prefrontal cortex-nucleus accumbens interaction: in vivo modulation by dopamine and glutamate in the prefrontal cortex
    Alberto Del Arco
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Madrid, Spain
    Pharmacol Biochem Behav 90:226-35. 2008
    ..Finally, it is speculated that environmental enrichment might produce plastic changes that modify the functional interaction between the PFC and the NAc in both physiological and pathological conditions...
  11. ncbi Environmental enrichment promotes neurogenesis and changes the extracellular concentrations of glutamate and GABA in the hippocampus of aged rats
    Gregorio Segovia
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, Madrid 28040, Spain
    Brain Res Bull 70:8-14. 2006
    ..These results suggest that enriched housing conditions change both neurogenesis in the dentate gyrus and glutamate and GABA levels in the CA3 area of the hippocampus of aged rats...
  12. ncbi Dopamine and GABA increases produced by activation of glutamate receptors in the nucleus accumbens are decreased during aging
    Gregorio Segovia
    Department of Physiology, Faculty of Medicine, Universidad Complutense, 28040 Madrid, Spain
    Neurobiol Aging 26:91-101. 2005
    ..These findings suggest that aging changes the interaction between the neurotransmitters glutamate and dopamine and glutamate and GABA in the nucleus accumbens of the freely moving rat...
  13. doi Aging impairs the control of prefrontal cortex on the release of corticosterone in response to stress and on memory consolidation
    Pedro Garrido
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Madrid, Spain
    Neurobiol Aging 33:827.e1-9. 2012
    ..These results suggest that prefrontal cortex loses its capacity to control hypothalamo-pituitary-adrenal (HPA) axis activity and the consolidation of emotional memory during aging...
  14. doi Aging increases basal but not stress-induced levels of corticosterone in the brain of the awake rat
    Pedro Garrido
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Madrid, Spain
    Neurobiol Aging 33:375-82. 2012
    ..These results suggest that the changes produced by aging in the brain may be related to the enhanced basal levels of free CORT and not to the CORT increases in response to stress...
  15. ncbi Effects of the metabotropic glutamate receptor agonist, ACPD, on the extracellular concentrations of GABA and acetylcholine in the prefrontal cortex of the rat during the normal process of aging
    Gregorio Segovia
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, 28040 Madrid, Spain
    Brain Res Bull 65:11-6. 2005
    ..These results suggest that the interaction GABA-glutamate in the prefrontal cortex, mediated by mGluRs, changes with age...
  16. doi Environmental enrichment, prefrontal cortex, stress, and aging of the brain
    Gregorio Segovia
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, Madrid 28040, Spain
    J Neural Transm 116:1007-16. 2009
    ..Finally we propose that a reduction in the stress-induced release of dopamine observed during aging in control animals might be an index of a better adaptation to stressful stimuli...
  17. doi Environmental enrichment increases the in vivo extracellular concentration of dopamine in the nucleus accumbens: a microdialysis study
    Gregorio Segovia
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, 28040 Madrid, Spain
    J Neural Transm 117:1123-30. 2010
    ..These findings may be relevant for the understanding of the effects of EE on motor behaviour...
  18. doi Neurotransmitters and prefrontal cortex-limbic system interactions: implications for plasticity and psychiatric disorders
    Alberto Del Arco
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Madrid, Spain
    J Neural Transm 116:941-52. 2009
    ..Finally, it is speculated that changes in the function of the PFC, associated with psychiatric disorders or due to environmental-dependent plasticity, can change PFC-limbic system interactions...
  19. ncbi Circadian rhythms of dopamine, glutamate and GABA in the striatum and nucleus accumbens of the awake rat: modulation by light
    Tamara R Castaneda
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Madrid, Spain
    J Pineal Res 36:177-85. 2004
    ..These findings show that in the striatum, dopamine but not glutamate and GABA, seem to be influenced by light. In the nucleus accumbens, however, the three neurotransmitters had a circadian rhythm, which was independent of light...
  20. ncbi NMDA and AMPA/kainate glutamatergic agonists increase the extracellular concentrations of GABA in the prefrontal cortex of the freely moving rat: modulation by endogenous dopamine
    Alberto Del Arco
    Department of Physiology, Faculty of Medicine, University Complutense, Ciudad Universitaria s n, 28040 Madrid, Spain
    Brain Res Bull 57:623-30. 2002
    ....
  21. ncbi Effects of CB1 cannabinoid receptor modulating compounds on the hyperkinesia induced by high-dose levodopa in the reserpine-treated rat model of Parkinson's disease
    Gregorio Segovia
    Division of Neuroscience, School of Biological Sciences, University of Manchester, Manchester, United Kingdom
    Mov Disord 18:138-49. 2003
    ....
  22. ncbi Perfusion of melatonin into the prefrontal cortex disrupts the circadian rhythm of acetylcholine but not of locomotor activity
    Blanca Marquez de Prado
    Department of Physiology, Faculty of Medicine, University Complutense of Madrid, Spain
    J Pineal Res 35:283-7. 2003
    ....