Angel Manteca

Summary

Affiliation: Universidad de Oviedo
Country: Spain

Publications

  1. doi request reprint Quantitative proteome analysis of Streptomyces coelicolor Nonsporulating liquid cultures demonstrates a complex differentiation process comparable to that occurring in sporulating solid cultures
    Angel Manteca
    Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, Odense M, DK 5230, Odense, Denmark
    J Proteome Res 9:4801-11. 2010
  2. doi request reprint Transcriptomic analysis of liquid non-sporulating Streptomyces coelicolor cultures demonstrates the existence of a complex differentiation comparable to that occurring in solid sporulating cultures
    Paula Yagüe
    Area de Microbiologia, Departamento de Biología Funcional and IUOPA, Facultad de Medicina, Universidad de Oviedo, Oviedo, Spain
    PLoS ONE 9:e86296. 2014
  3. pmc Transcriptomic analysis of Streptomyces coelicolor differentiation in solid sporulating cultures: first compartmentalized and second multinucleated mycelia have different and distinctive transcriptomes
    Paula Yagüe
    Area de Microbiologia, Departamento de Biología Funcional and Instituto Universitario de Biotecnología de Asturias, Universidad de Oviedo, Oviedo, Spain
    PLoS ONE 8:e60665. 2013
  4. doi request reprint Phosphoproteome analysis of Streptomyces development reveals extensive protein phosphorylation accompanying bacterial differentiation
    Angel Manteca
    Area de Microbiologia, Departamento de Biologia Funcional and IUBA, Facultad de Medicina, Universidad de Oviedo, 33006 Oviedo, Spain
    J Proteome Res 10:5481-92. 2011
  5. pmc Quantitative proteomics analysis of Streptomyces coelicolor development demonstrates that onset of secondary metabolism coincides with hypha differentiation
    Angel Manteca
    double daggerProtein Research Group, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, DK 5230 Odense M, Denmark
    Mol Cell Proteomics 9:1423-36. 2010
  6. doi request reprint A rare case of silicone mammary implant infection by Streptomyces spp. in a patient with breast reconstruction after mastectomy: taxonomic characterization using molecular techniques
    Angel Manteca
    Departamento de Biologia Funcional, Instituto Universitario de Biotecnologia de Asturias, Universidad de Oviedo, Oviedo, Asturias, Spain
    Diagn Microbiol Infect Dis 63:390-3. 2009
  7. pmc Streptomyces development in colonies and soils
    Angel Manteca
    Area de Microbiologia, Departamento de Biologia Funcional e IUBA, Facultad de Medicina, Universidad de Oviedo, 33006 Oviedo, Spain
    Appl Environ Microbiol 75:2920-4. 2009
  8. pmc Mycelium differentiation and antibiotic production in submerged cultures of Streptomyces coelicolor
    Angel Manteca
    Area de Microbiologia, Departamento de Biologia Funcional and IUBA, Facultad de Medicina, Universidad de Oviedo, 33006 Oviedo, Spain
    Appl Environ Microbiol 74:3877-86. 2008
  9. ncbi request reprint A rare case of lung coinfection by Streptomyces cinereoruber and Haemophilus influenzae in a patient with severe chronic obstructive pulmonary disease: characterization at species level using molecular techniques
    Angel Manteca
    Area de Microbiologia, Departamento de Biologia Funcional, Instituto Universitario de Biotecnologia de Asturias IUBA, Universidad de Oviedo, 33006 Oviedo, Asturias, Spain
    Diagn Microbiol Infect Dis 60:307-11. 2008
  10. pmc Mycelium development in Streptomyces antibioticus ATCC11891 occurs in an orderly pattern which determines multiphase growth curves
    Angel Manteca
    Universidad de Oviedo, Facultad de Medicina, Area de Microbiologia, Departamento de Biologia Funcional, 33006, Julian Claveria s n, Oviedo, Spain
    BMC Microbiol 5:51. 2005

Collaborators

Detail Information

Publications24

  1. doi request reprint Quantitative proteome analysis of Streptomyces coelicolor Nonsporulating liquid cultures demonstrates a complex differentiation process comparable to that occurring in sporulating solid cultures
    Angel Manteca
    Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, Odense M, DK 5230, Odense, Denmark
    J Proteome Res 9:4801-11. 2010
    ..The most remarkable protein abundance differences between MII from solid and liquid cultures were associated with the final stages of hyphae compartmentalization and spore formation...
  2. doi request reprint Transcriptomic analysis of liquid non-sporulating Streptomyces coelicolor cultures demonstrates the existence of a complex differentiation comparable to that occurring in solid sporulating cultures
    Paula Yagüe
    Area de Microbiologia, Departamento de Biología Funcional and IUOPA, Facultad de Medicina, Universidad de Oviedo, Oviedo, Spain
    PLoS ONE 9:e86296. 2014
    ....
  3. pmc Transcriptomic analysis of Streptomyces coelicolor differentiation in solid sporulating cultures: first compartmentalized and second multinucleated mycelia have different and distinctive transcriptomes
    Paula Yagüe
    Area de Microbiologia, Departamento de Biología Funcional and Instituto Universitario de Biotecnología de Asturias, Universidad de Oviedo, Oviedo, Spain
    PLoS ONE 8:e60665. 2013
    ....
  4. doi request reprint Phosphoproteome analysis of Streptomyces development reveals extensive protein phosphorylation accompanying bacterial differentiation
    Angel Manteca
    Area de Microbiologia, Departamento de Biologia Funcional and IUBA, Facultad de Medicina, Universidad de Oviedo, 33006 Oviedo, Spain
    J Proteome Res 10:5481-92. 2011
    ..We thus established for the first time the widespread occurrence and dynamic features of Ser/Thr/Tyr protein phosphorylation in a bacteria species and also revealed a previously unrecognized phosphorylation motif "x(pT)xEx"...
  5. pmc Quantitative proteomics analysis of Streptomyces coelicolor development demonstrates that onset of secondary metabolism coincides with hypha differentiation
    Angel Manteca
    double daggerProtein Research Group, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, DK 5230 Odense M, Denmark
    Mol Cell Proteomics 9:1423-36. 2010
    ..Comparative bioinformatics analyses revealed the switch from primary to secondary metabolism between the initial compartmentalized mycelium and the multinucleated hyphae...
  6. doi request reprint A rare case of silicone mammary implant infection by Streptomyces spp. in a patient with breast reconstruction after mastectomy: taxonomic characterization using molecular techniques
    Angel Manteca
    Departamento de Biologia Funcional, Instituto Universitario de Biotecnologia de Asturias, Universidad de Oviedo, Oviedo, Asturias, Spain
    Diagn Microbiol Infect Dis 63:390-3. 2009
    ..isolated from a patient who had had breast reconstruction after a mastectomy was identified at the species level by comparative sequence analysis of 16S ribosomal DNA (rDNA) and the hypervariable alpha-region of the 16S rDNA...
  7. pmc Streptomyces development in colonies and soils
    Angel Manteca
    Area de Microbiologia, Departamento de Biologia Funcional e IUBA, Facultad de Medicina, Universidad de Oviedo, 33006 Oviedo, Spain
    Appl Environ Microbiol 75:2920-4. 2009
    ..The mycelial growth rate was much lower than that in standard laboratory cultures, and the life span of the previously named first compartmentalized mycelium was remarkably increased...
  8. pmc Mycelium differentiation and antibiotic production in submerged cultures of Streptomyces coelicolor
    Angel Manteca
    Area de Microbiologia, Departamento de Biologia Funcional and IUBA, Facultad de Medicina, Universidad de Oviedo, 33006 Oviedo, Spain
    Appl Environ Microbiol 74:3877-86. 2008
    ..This work is the first to report on the relationship between differentiation processes and secondary metabolite production in submerged Streptomyces cultures...
  9. ncbi request reprint A rare case of lung coinfection by Streptomyces cinereoruber and Haemophilus influenzae in a patient with severe chronic obstructive pulmonary disease: characterization at species level using molecular techniques
    Angel Manteca
    Area de Microbiologia, Departamento de Biologia Funcional, Instituto Universitario de Biotecnologia de Asturias IUBA, Universidad de Oviedo, 33006 Oviedo, Asturias, Spain
    Diagn Microbiol Infect Dis 60:307-11. 2008
    ..Restriction fragment length polymorphism, morphologic, and biochemical characteristics have confirmed their identity...
  10. pmc Mycelium development in Streptomyces antibioticus ATCC11891 occurs in an orderly pattern which determines multiphase growth curves
    Angel Manteca
    Universidad de Oviedo, Facultad de Medicina, Area de Microbiologia, Departamento de Biologia Funcional, 33006, Julian Claveria s n, Oviedo, Spain
    BMC Microbiol 5:51. 2005
    ..Hence, this vertical description assumes that the development in the pre-sporulating phases is more or less homogeneous in all zones of the plate surface...
  11. ncbi request reprint A proteomic analysis of Streptomyces coelicolor programmed cell death
    Angel Manteca
    Area de Microbiologia, Departamento de Biologia Funcional and IUBA, Facultad de Medicina, Universidad de Oviedo, Oviedo, Spain
    Proteomics 6:6008-22. 2006
    ..The increased amounts of several antioxidant proteins suggest oxidative stress as either the cause or consequence of the cell death...
  12. pmc A fatal case of Nocardia otitidiscaviarum pulmonary infection and brain abscess: taxonomic characterization by molecular techniques
    Ana Isabel Pelaez
    Universidad de Oviedo, Area de Microbiologia, Departamento de Biologia Funcional, Facultad de Medicina, Oviedo, Spain
    Ann Clin Microbiol Antimicrob 8:11. 2009
    ..Taxonomic identification involved phenotypic testing, restriction fragment length polymorphism (RFLP), and complete 16S rRNA gene sequencing...
  13. ncbi request reprint A death round affecting a young compartmentalized mycelium precedes aerial mycelium dismantling in confluent surface cultures of Streptomyces antibioticus
    Angel Manteca
    Area de Microbiologia, Departamento de Biologia Funcional, Facultad de Medicina, Universidad de Oviedo, Julian Claveria s n, 33006 Oviedo, Spain
    Microbiology 151:3689-97. 2005
    ....
  14. doi request reprint Antitumor activity of new enantiopure pybox-ruthenium complexes
    Estefania Menéndez-Pedregal
    Departamento de Quimica Organica e Inorganica, Instituto de Química Organometálica Enrique Moles Unidad Asociada al C S I C Universidad de Oviedo, 33006 Oviedo, Principado de Asturias, Spain
    Dalton Trans 42:13955-67. 2013
    ....
  15. ncbi request reprint Cytological and biochemical evidence for an early cell dismantling event in surface cultures of Streptomyces antibioticus
    Angel Manteca
    Area de Microbiologia, Departamento de Biologia Funcional, Facultad de Medicina, Universidad de Oviedo, 33006 Oviedo, Spain
    Res Microbiol 157:143-52. 2006
    ..Calcium-dependent proteolytic activation of a precursor of nucleases and the nucleolytic formation of a ladder of chromosomal bands are conspicuous events associated with the initiation of the death process...
  16. pmc Pre-sporulation stages of Streptomyces differentiation: state-of-the-art and future perspectives
    Paula Yagüe
    Area de Microbiologia, Departamento de Biologia Funcional, and IUBA, Facultad de Medicina, Universidad de Oviedo, Oviedo, Spain
    FEMS Microbiol Lett 342:79-88. 2013
    ..In this work, we review the current knowledge on Streptomyces pre-sporulation stages of Streptomyces differentiation...
  17. pmc New method for monitoring programmed cell death and differentiation in submerged Streptomyces cultures
    Paula Yagüe
    Area de Microbiologia, Departamento de Biologia Funcional de IUBA, Facultad de Medicina, Universidad de Oviedo, 33006 Oviedo, Spain
    Appl Environ Microbiol 76:3401-4. 2010
    ..The experimental approach described opens the possibility of designing online protocols for automatic monitoring of industrial fermentations...
  18. ncbi request reprint Actinobacteria cyclophilins: phylogenetic relationships and description of new class- and order-specific paralogues
    Angel Manteca
    Area de Microbiologia, Departamento de Biologia Funcional and IUBA, Universidad de Oviedo, Julian Claveria s n, Oviedo, 33006, Spain
    J Mol Evol 63:719-32. 2006
    ..Southern and Western blot experiments were performed to determine the taxonomic distribution of the different cyclophilins in Actinobacteria...
  19. pmc Streptomyces albus isolated from a human actinomycetoma and characterized by molecular techniques
    María Cruz Martín
    Instituto de Productos Lácteos de Asturias CSIC, Villaviciosa, Oviedo, Spain
    J Clin Microbiol 42:5957-60. 2004
    ....
  20. pmc Mycelium differentiation and development of Streptomyces coelicolor in lab-scale bioreactors: programmed cell death, differentiation, and lysis are closely linked to undecylprodigiosin and actinorhodin production
    Beatriz Rioseras
    Area de Microbiologia, Departamento de Biología Funcional e IUOPA, Facultad de Medicina, Universidad de Oviedo, 33006 Oviedo, Spain
    Bioresour Technol 151:191-8. 2014
    ..Differentiation was demonstrated to be one of the keys to interpreting biophysical fermentation parameters and to rationalizing the optimization of secondary metabolite production in bioreactors. ..
  21. ncbi request reprint Aerial hyphae in surface cultures of Streptomyces lividans and Streptomyces coelicolor originate from viable segments surviving an early programmed cell death event
    Angel Manteca
    Departamento de Biologia Funcional e Instituto de Biotecnologia de Asturias IUBA, Universidad de Oviedo, Oviedo, Spain
    FEMS Microbiol Lett 274:118-25. 2007
    ....
  22. pmc Recombinant cyclophilins lack nuclease activity
    Angel Manteca
    Universidad de Oviedo, Departamento de Biologia Funcional, Area de Microbiologia, Julian Claveria s n, Oviedo 33006, Spain
    J Bacteriol 186:6325-6. 2004
    ....
  23. doi request reprint Antitumor activity of new hydridotris(pyrazolyl)borate ruthenium(II) complexes containing the phosphanes PTA and 1-CH3-PTA
    Almudena García-Fernández
    Departamento de Quimica Organica e Inorganica, Instituto de Química Organometálica Enrique Moles Unidad Asociada al C S I C Universidad de Oviedo, 33006, Oviedo, Spain
    Dalton Trans 39:10186-96. 2010
    ..Some of these new compounds show promising cytotoxic activity with IC(50) values in the low micromolar range, and display differential effects on cancer and normal cell growth...
  24. ncbi request reprint Cloning and characterization of a Streptomyces antibioticus ATCC11891 cyclophilin related to Gram negative bacteria cyclophilins
    Angel Manteca
    Departamento de Biologia, Funcional, Facultad de Medicina, Universidad de Oviedo, Oviedo 33006, Spain
    FEBS Lett 572:19-26. 2004
    ..The presence of SanCyp18 in Streptomyces is likely due to horizontal gene transmission from Gram-negative bacteria to Streptomyces...