Carlos Mackintosh

Summary

Affiliation: Universidad de Salamanca
Country: Spain

Publications

  1. doi request reprint 1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma
    C Mackintosh
    Molecular Pathology Program, Centro de Investigación del Cáncer IBMCC USAL CSIC, Campus Miguel de Unamuno s n, Salamanca, Spain
    Oncogene 31:1287-98. 2012
  2. ncbi request reprint Mining sarcomas by proteomics approaches: Ewing sarcoma on the spotlight
    Carlos Mackintosh
    Molecular Pathology Program, Centro de Investigación del Cáncer IBMCC, Universidad de Salamanca CSIC, Salamanca, 37007, Spain
    Recent Pat Biotechnol 7:98-111. 2013
  3. doi request reprint A pivotal role for heat shock protein 90 in Ewing sarcoma resistance to anti-insulin-like growth factor 1 receptor treatment: in vitro and in vivo study
    Ana Sofia Martins
    Laboratory 20 Molecular Pathology, Centro de Investigación del Cáncer Instituto de Biología Molecular y Celular del Cáncer, Universidad de Salamanca Consejo Superior de Investigaciones Cientificas, Salamanca, Spain
    Cancer Res 68:6260-70. 2008
  4. doi request reprint The clinical relevance of molecular genetics in soft tissue sarcomas
    José Luis Ordóñez
    Centro de Investigación del Cáncer IBMCC, Universidad de Salamanca CSIC, Spain
    Adv Anat Pathol 17:162-81. 2010
  5. ncbi request reprint The molecular pathogenesis of Ewing's sarcoma
    Carlos Mackintosh
    Laboratory of Molecular Pathology of Sarcomas, Centro de Investigación del Cáncer Instituto de Biología Molecular y Celular del Cáncer, Universidad de Salamanca CSIC, Salamanca, Spain
    Cancer Biol Ther 9:655-67. 2010
  6. ncbi request reprint Insulin-like growth factor I receptor pathway inhibition by ADW742, alone or in combination with imatinib, doxorubicin, or vincristine, is a novel therapeutic approach in Ewing tumor
    Ana S Martins
    Laboratory 20 Molecular Pathology, Centro de Investigación del Cáncer Instituto de Biología Molecular y Celular del Cáncer, Universidad de Salamanca Consejo Superior de Investigaciones Cientificas, Salamanca, Spain
    Clin Cancer Res 12:3532-40. 2006
  7. doi request reprint Array-based comparative genomic hybridization of mapped BAC DNA clones to screen for chromosome 14 copy number abnormalities in meningiomas
    Ana Belén Espinosa
    Unidad de Investigacion, Hospital Universitario de Salamanca, Salamanca, Spain
    Eur J Hum Genet 16:1450-8. 2008

Collaborators

  • Alberto Orfao
  • E de Alava
  • K Scotlandi
  • P Picci
  • R Sciot
  • Angel Maillo
  • Juan Madoz-Gurpide
  • José Luis Ordóñez
  • Daniel Osuna
  • Teresa Hernandez
  • Ana Sofia Martins
  • Ana Belén Espinosa
  • Ana S Martins
  • Maria Victoria Barbado
  • Ana Pastora Otero-Motta
  • Ana Teresa Amaral
  • Daniel J García-Domínguez
  • María Victoria Sevillano
  • Victoria Sevillano
  • Ana Pastora Otero
  • David Herrero
  • Pablo Sousa
  • Gemma Caballero
  • Christopher Poremba
  • Maria Dolores Tabernero
  • Laura Gutierrez
  • Javier Ortiz
  • Alfredo Garcia-Sanchez
  • Marta Merino
  • Maria Campos
  • David Herrero Martín

Detail Information

Publications7

  1. doi request reprint 1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma
    C Mackintosh
    Molecular Pathology Program, Centro de Investigación del Cáncer IBMCC USAL CSIC, Campus Miguel de Unamuno s n, Salamanca, Spain
    Oncogene 31:1287-98. 2012
    ....
  2. ncbi request reprint Mining sarcomas by proteomics approaches: Ewing sarcoma on the spotlight
    Carlos Mackintosh
    Molecular Pathology Program, Centro de Investigación del Cáncer IBMCC, Universidad de Salamanca CSIC, Salamanca, 37007, Spain
    Recent Pat Biotechnol 7:98-111. 2013
    ....
  3. doi request reprint A pivotal role for heat shock protein 90 in Ewing sarcoma resistance to anti-insulin-like growth factor 1 receptor treatment: in vitro and in vivo study
    Ana Sofia Martins
    Laboratory 20 Molecular Pathology, Centro de Investigación del Cáncer Instituto de Biología Molecular y Celular del Cáncer, Universidad de Salamanca Consejo Superior de Investigaciones Cientificas, Salamanca, Spain
    Cancer Res 68:6260-70. 2008
    ..Accordingly, HSP90 expression could be a predictive factor of response to IGF1R-targeting therapies...
  4. doi request reprint The clinical relevance of molecular genetics in soft tissue sarcomas
    José Luis Ordóñez
    Centro de Investigación del Cáncer IBMCC, Universidad de Salamanca CSIC, Spain
    Adv Anat Pathol 17:162-81. 2010
    ..This review describes the clinical application of some of the molecular alterations found in sarcomas, some advances in the field of sarcomagenesis, and the development of animal models...
  5. ncbi request reprint The molecular pathogenesis of Ewing's sarcoma
    Carlos Mackintosh
    Laboratory of Molecular Pathology of Sarcomas, Centro de Investigación del Cáncer Instituto de Biología Molecular y Celular del Cáncer, Universidad de Salamanca CSIC, Salamanca, Spain
    Cancer Biol Ther 9:655-67. 2010
    ..Identification of EWS-ETS target genes and their role in tumor signaling networks together with the unravelling of the cell of origin will facilitate the translation into new treatment modalities for these neoplasms...
  6. ncbi request reprint Insulin-like growth factor I receptor pathway inhibition by ADW742, alone or in combination with imatinib, doxorubicin, or vincristine, is a novel therapeutic approach in Ewing tumor
    Ana S Martins
    Laboratory 20 Molecular Pathology, Centro de Investigación del Cáncer Instituto de Biología Molecular y Celular del Cáncer, Universidad de Salamanca Consejo Superior de Investigaciones Cientificas, Salamanca, Spain
    Clin Cancer Res 12:3532-40. 2006
    ..We recently showed the cytostatic role of imatinib, an inhibitor of the SCF-KIT loop, on Ewing tumor cells, and in this study, we intend to analyze the inhibition of the insulin-like growth factor I receptor (IGF1R) loop...
  7. doi request reprint Array-based comparative genomic hybridization of mapped BAC DNA clones to screen for chromosome 14 copy number abnormalities in meningiomas
    Ana Belén Espinosa
    Unidad de Investigacion, Hospital Universitario de Salamanca, Salamanca, Spain
    Eur J Hum Genet 16:1450-8. 2008
    ....