Research Topics
| Nicole Maca-MeyerSummaryAffiliation: Universidad de La Laguna Country: Spain Publications
|
Detail Information
Publications
Reduced genetic structure of the Iberian peninsula revealed by Y-chromosome analysis: implications for population demographyCarlos Flores
Departamento de Genetica, Universidad de La Laguna, Tenerife E 38271, Spain
Eur J Hum Genet 12:855-63. 2004..These results indicate that neither old or recent Levantine expansions nor North African contacts have influenced the current Iberian Y-chromosome diversity so that geographical patterns can be identified...- Mitochondrial DNA diversity in 17th-18th century remains from Tenerife (Canary Islands)Nicole Maca-Meyer
, Universidad de La Laguna, 38271 La Laguna, Tenerife, Spain
Am J Phys Anthropol 127:418-26. 2005..59%), has also decreased due to European input. Finally, the presence of Amerindian lineages (1.5%) reveals that the Canary Islands have also received genetic flow from America... 
Major genomic mitochondrial lineages delineate early human expansionsN Maca-Meyer
Department of Genetics, Faculty of Biology, University of La Laguna, Tenerife, 38271, Spain
BMC Genet 2:13. 2001..As a new contribution to this study we have phylogenetically analysed complete mitochondrial DNA(mtDNA) sequences from 42 human lineages, representing major clades with known geographic assignation...- Mitochondrial DNA transit between West Asia and North Africa inferred from U6 phylogeographyNicole Maca-Meyer
Departamento de Genetica, Facultad de Biologia, Universidad de La Laguna, Tenerife, Spain
BMC Genet 4:15. 2003..We report here a more detailed analysis of this lineage, unraveling successive expansions that affected not only Africa but neighboring regions such as the Near East, the Iberian Peninsula and the Canary Islands... 
Mitochondrial DNA variation in Jordanians and their genetic relationship to other Middle East populationsAna M Gonzalez
Departamento de Genetica, Facultad de Biologia, Universidad de La Laguna, Tenerife, Spain
Ann Hum Biol 35:212-31. 2008..Although some mitochondrial DNA (mtDNA) studies have been carried out in this region, they have not included the Jordan area. This paper deals with the mtDNA composition of two Jordan populations...- Mitochondrial DNA affinities at the Atlantic fringe of EuropeAna M Gonzalez
Departamento de Genetica, Universidad de La Laguna, 38271 La Laguna, Tenerife, Spain
Am J Phys Anthropol 120:391-404. 2003..001) in this area compared to North Africa (0.006 +/- 0.001), we reject the proposal that only historic events such as the Moslem occupation are the main cause of this gene flow, and instead propose a pre-Neolithic origin for it... - Isolates in a corridor of migrations: a high-resolution analysis of Y-chromosome variation in JordanCarlos Flores
, , Universidad de La Laguna, 38271 Tenerife, Spain
J Hum Genet 50:435-41. 2005..These results demonstrate that, at a fine scale, the smooth, continental clines detected for several Y-chromosome markers are often disrupted by genetically divergent populations... - Bench-to-bedside review: understanding genetic predisposition to sepsisJesus Villar
Division Critical Care Research, Research Institute, Hospital Universitario NS de Candelaria, Tenerife, Canary Islands, Spain
Crit Care 8:180-9. 2004..We envision a time in the near future when genotyping will be include in the standard evaluation of critically ill patients and will help to prioritize a therapeutic option... - Ancient mtDNA analysis and the origin of the GuanchesNicole Maca-Meyer
, Universidad de La Laguna, Tenerife, Spain
Eur J Hum Genet 12:155-62. 2004..Although the Berbers are the most probable ancestors of the Guanches, it is deduced that important human movements have reshaped Northwest Africa after the migratory wave to the Canary Islands... - Description of a simple multiplex PCR-SSCP method for AB0 genotyping and its application to the peopling of the Canary IslandsRosa Fregel
, , Universidad de La Laguna, Tenerife, Spain
Immunogenetics 57:572-8. 2005..Similar to previous autosomal studies, admixture estimations point to a major Iberian contribution (82 +/- 0.5%) to the Canary Islands, although, in some islands as La Gomera, the NW African component raised to 62 +/- 4.3%... - Alu polymorphisms in Jerba Island population (Tunisia): comparative study in Arab and Berber groupsHajer Ennafaa
Laboratory of Genetics, Immunology and Human Pathologies, Faculty of Sciences of Tunis, Tunis, Tunisia
Ann Hum Biol 33:634-40. 2006..This study also revealed that Arabs from Jerba present close genetic distances to other North African populations, whilst Berbers of Jerba occupy an intermediate position among Mediterranean populations... - A CXCL2 polymorphism is associated with better outcomes in patients with severe sepsisJesus Villar
Multidisciplinary Organ Dysfunction Evaluation Research Network, Hospital Universitario Dr Negrin, Las Palmas de Gran Canaria, Canary Islands, Spain
Crit Care Med 35:2292-7. 2007..We hypothesized that a tandem repeat polymorphism (AC)n in the CXCL2 gene, previously associated with susceptibility to severe sepsis, contributes to morbidity and mortality in severe sepsis... - Angiotensin-converting enzyme insertion/deletion polymorphism is not associated with susceptibility and outcome in sepsis and acute respiratory distress syndromeJesus Villar
Multidisciplinary Organ Dysfunction Evaluation Research Network MODERN, Research Unit, Hospital Universitario Dr Negrin, Barranco de la Ballena, Las Palmas de Gran Canaria, Canary Islands, Spain
Intensive Care Med 34:488-95. 2008..We hypothesized that the I/D polymorphism also confers susceptibility to sepsis and is a predisposing factor for morbidity and mortality of patients with severe sepsis...