Sara Gonzalez

Summary

Affiliation: Universidad Complutense
Country: Spain

Publications

  1. ncbi request reprint Cannabinoid tolerance and dependence: a review of studies in laboratory animals
    Sara Gonzalez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Pharmacol Biochem Behav 81:300-18. 2005
  2. ncbi request reprint Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine
    Sara Gonzalez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, Ciudad Universitaria s n, 28040 Madrid, Spain
    Brain Res 954:73-81. 2002
  3. ncbi request reprint Region-dependent changes in endocannabinoid transmission in the brain of morphine-dependent rats
    Sara Gonzalez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Addict Biol 8:159-66. 2003
  4. ncbi request reprint Effects of rimonabant, a selective cannabinoid CB1 receptor antagonist, in a rat model of Parkinson's disease
    Sara Gonzalez
    Department of Biochemistry and Molecular Biology, Faculty of Medicine, Complutense University, 28040 Madrid, Spain
    Brain Res 1073:209-19. 2006
  5. ncbi request reprint Behavioral and molecular changes elicited by acute administration of SR141716 to Delta9-tetrahydrocannabinol-tolerant rats: an experimental model of cannabinoid abstinence
    Sara Gonzalez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Drug Alcohol Depend 74:159-70. 2004
  6. pmc Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease
    Onintza Sagredo
    Departamento de Bioquímica y Biología Molecular and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas CIBERNED, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Glia 57:1154-67. 2009
  7. ncbi request reprint Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties
    Moisés García-Arencibia
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Brain Res 1134:162-70. 2007
  8. pmc Changes in endocannabinoid contents in reward-related brain regions of alcohol-exposed rats, and their possible relevance to alcohol relapse
    Sara Gonzalez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, Ciudad Universitaria s n, 28040 Madrid, Spain
    Br J Pharmacol 143:455-64. 2004
  9. ncbi request reprint Therapeutic potential of the endocannabinoid system in the brain
    Jose Antonio Ramos
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Mini Rev Med Chem 5:609-17. 2005
  10. ncbi request reprint Cannabinoid CB(1) receptors in the basal ganglia and motor response to activation or blockade of these receptors in parkin-null mice
    Sara Gonzalez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Brain Res 1046:195-206. 2005

Detail Information

Publications11

  1. ncbi request reprint Cannabinoid tolerance and dependence: a review of studies in laboratory animals
    Sara Gonzalez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Pharmacol Biochem Behav 81:300-18. 2005
    ..The present review article will address all these aspects trying to establish the bases for future research...
  2. ncbi request reprint Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine
    Sara Gonzalez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, Ciudad Universitaria s n, 28040 Madrid, Spain
    Brain Res 954:73-81. 2002
    ....
  3. ncbi request reprint Region-dependent changes in endocannabinoid transmission in the brain of morphine-dependent rats
    Sara Gonzalez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Addict Biol 8:159-66. 2003
    ....
  4. ncbi request reprint Effects of rimonabant, a selective cannabinoid CB1 receptor antagonist, in a rat model of Parkinson's disease
    Sara Gonzalez
    Department of Biochemistry and Molecular Biology, Faculty of Medicine, Complutense University, 28040 Madrid, Spain
    Brain Res 1073:209-19. 2006
    ..Therefore, the elucidation of the neurochemical substrate involved in this effect remains a major challenge for the future...
  5. ncbi request reprint Behavioral and molecular changes elicited by acute administration of SR141716 to Delta9-tetrahydrocannabinol-tolerant rats: an experimental model of cannabinoid abstinence
    Sara Gonzalez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Drug Alcohol Depend 74:159-70. 2004
    ..This is indicative of the existence of a withdrawal syndrome in cannabinoid-tolerant rats that is mild compared with abstinence in opioid-dependent rats...
  6. pmc Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease
    Onintza Sagredo
    Departamento de Bioquímica y Biología Molecular and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas CIBERNED, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Glia 57:1154-67. 2009
    ..Altogether, our results support the hypothesis that CB2 receptors could constitute a therapeutic target to slowdown neurodegeneration in HD...
  7. ncbi request reprint Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties
    Moisés García-Arencibia
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Brain Res 1134:162-70. 2007
    ..In addition, the activation of CB2 (but not CB1) receptors, or other additional mechanisms, might also contribute to some extent to the potential of cannabinoids in this disease...
  8. pmc Changes in endocannabinoid contents in reward-related brain regions of alcohol-exposed rats, and their possible relevance to alcohol relapse
    Sara Gonzalez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, Ciudad Universitaria s n, 28040 Madrid, Spain
    Br J Pharmacol 143:455-64. 2004
    ....
  9. ncbi request reprint Therapeutic potential of the endocannabinoid system in the brain
    Jose Antonio Ramos
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Mini Rev Med Chem 5:609-17. 2005
    ....
  10. ncbi request reprint Cannabinoid CB(1) receptors in the basal ganglia and motor response to activation or blockade of these receptors in parkin-null mice
    Sara Gonzalez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Brain Res 1046:195-206. 2005
    ....
  11. ncbi request reprint Chronic exposure to morphine, cocaine or ethanol in rats produced different effects in brain cannabinoid CB(1) receptor binding and mRNA levels
    Sara Gonzalez
    Departamento de Bioquijmica y Biologija Molecular, Facultad de Medicina, Universidad Complutense, 2804, Madrid, Spain
    Drug Alcohol Depend 66:77-84. 2002
    ..Alcohol did not produce any effects on CB(1) receptor binding and mRNA levels, whereas cocaine only affected transcript levels in selected regions and morphine produced divergent and region-dependent effects...