Bruno Gonzalez-Zorn

Summary

Affiliation: Universidad Complutense
Country: Spain

Publications

  1. pmc 16S rRNA methyltransferase RmtC in Salmonella enterica serovar Virchow
    Katie L Hopkins
    Health Protection Agency Centre for Infections, London, UK
    Emerg Infect Dis 16:712-5. 2010
  2. ncbi request reprint Ecology of antimicrobial resistance: humans, animals, food and environment
    Bruno Gonzalez-Zorn
    Department of Animal Health, Veterinary Faculty, Complutense University, Madrid, Spain
    Int Microbiol 15:101-9. 2012
  3. pmc Prevalence of SOS-mediated control of integron integrase expression as an adaptive trait of chromosomal and mobile integrons
    Guillaume Cambray
    Institut Pasteur, Unité Plasticité du Génome Bactérien, CNRS URA 2171, 75015 Paris, France
    Mob DNA 2:6. 2011
  4. ncbi request reprint Genetic basis for dissemination of armA
    Bruno Gonzalez-Zorn
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain
    J Antimicrob Chemother 56:583-5. 2005
  5. pmc armA and aminoglycoside resistance in Escherichia coli
    Bruno Gonzalez-Zorn
    Universidad Complutense de Madrid, Madrid, Spain
    Emerg Infect Dis 11:954-6. 2005
  6. pmc Klebsiella pneumoniae sequence type 11 from companion animals bearing ArmA methyltransferase, DHA-1 β-lactamase, and QnrB4
    Laura Hidalgo
    Department of Animal Health and VISAVET, Universidad Complutense de Madrid, Madrid, Spain
    Antimicrob Agents Chemother 57:4532-4. 2013
  7. pmc Fitness cost and interference of Arm/Rmt aminoglycoside resistance with the RsmF housekeeping methyltransferases
    Belen Gutierrez
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain
    Antimicrob Agents Chemother 56:2335-41. 2012
  8. pmc Fluoroquinolone efflux in Streptococcus suis is mediated by SatAB and not by SmrA
    Jose Antonio Escudero
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain
    Antimicrob Agents Chemother 55:5850-60. 2011
  9. pmc Haemophilus influenzae clinical isolates with plasmid pB1000 bearing blaROB-1: fitness cost and interspecies dissemination
    Alvaro San Millan
    Departamento de Sanidad Animal, Universidad Complutense de Madrid, 28040 Madrid, Spain
    Antimicrob Agents Chemother 54:1506-11. 2010
  10. pmc SatR is a repressor of fluoroquinolone efflux pump SatAB
    Jose Antonio Escudero
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain
    Antimicrob Agents Chemother 57:3430-3. 2013

Collaborators

  • Rafael Frandoloso
  • Marina Cerquetti
  • Miguel A Moreno
  • Patrice Courvalin
  • Jose Campos
  • Stephen Douthwaite
  • Katie L Hopkins
  • Manal Abuoun
  • Marc Galimand
  • Kashi N Prasad
  • Alvaro San Millan
  • Jose Antonio Escudero
  • Laura Hidalgo
  • Belen Gutierrez
  • Lucas Dominguez
  • Laura Carrilero
  • Cristina M Ovejero
  • Monica Suarez
  • Courage Kosi Setsoafia Saba
  • Alfonso Santos-Lopez
  • Daniel Thomas-Lopez
  • Sophie A Granier
  • Guillaume Cambray
  • Jose A Vazquez-Boland
  • Sonia Martinez
  • Adela G de la Campa
  • Ana Catalan
  • Gustavo Domínguez-Bernal
  • Mariela Scortti
  • Emilia López-Solanilla
  • Isabel Chico-Calero
  • Andreas Hoefer
  • Bawa Demuyakor
  • Maria Concepción Porrero
  • Silvia Herrera-León
  • Cristina Martinez Ovejero
  • Suruchi Shukla
  • Courage K S Saba
  • Carmen Martin-Espada
  • Neil Woodford
  • Gloria Santurde
  • Stephanie Matrat
  • Natalia Montero
  • Jose A Escudero
  • Susana Campoy
  • Marie Cecile Ploy
  • Anne Brisabois
  • Ivan Erill
  • Didier Mazel
  • Neus Sanchez-Alberola
  • Emilie Guerin
  • Roberto M La Ragione
  • Jordi Barbe
  • Sandra Da Re
  • Maria Giufre
  • María José Ferrándiz
  • Silvia García-Cobos
  • César B Gutiérrez-Martín
  • Elías F Rodríguez-Ferri
  • Nerea Garcia
  • Montserrat Llagostera
  • Silvia Nieto
  • Magdalena Gibert
  • Gema Lopez
  • Estefania Rivero
  • Fidel Farelo
  • Petra Herrmann
  • Hector J Monzo
  • Stefanie Müller-Altrock
  • Jürgen Kreft
  • Lizeth Lacharme
  • Pablo Rodriguez-Palenzuela
  • Susana Novella
  • Werner Goebel
  • Jörg Slaghuis

Detail Information

Publications21

  1. pmc 16S rRNA methyltransferase RmtC in Salmonella enterica serovar Virchow
    Katie L Hopkins
    Health Protection Agency Centre for Infections, London, UK
    Emerg Infect Dis 16:712-5. 2010
    ..enterica serovar Virchow isolates from clinical samples and food. All isolates were clonally related and bore the rmtC gene on the bacterial chromosome. Surveillance for and research on these resistance determinants are essential...
  2. ncbi request reprint Ecology of antimicrobial resistance: humans, animals, food and environment
    Bruno Gonzalez-Zorn
    Department of Animal Health, Veterinary Faculty, Complutense University, Madrid, Spain
    Int Microbiol 15:101-9. 2012
    ..Collaborative horizontal research scenarios should be envisaged and involve all actors working with humans, animals, food and the environment...
  3. pmc Prevalence of SOS-mediated control of integron integrase expression as an adaptive trait of chromosomal and mobile integrons
    Guillaume Cambray
    Institut Pasteur, Unité Plasticité du Génome Bactérien, CNRS URA 2171, 75015 Paris, France
    Mob DNA 2:6. 2011
    ..abstract:..
  4. ncbi request reprint Genetic basis for dissemination of armA
    Bruno Gonzalez-Zorn
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain
    J Antimicrob Chemother 56:583-5. 2005
    ..In order to elucidate the genetic basis for the spread of armA, we have determined the complete nucleotide sequence of pMUR050...
  5. pmc armA and aminoglycoside resistance in Escherichia coli
    Bruno Gonzalez-Zorn
    Universidad Complutense de Madrid, Madrid, Spain
    Emerg Infect Dis 11:954-6. 2005
    ..The resistance gene was borne by self-transferable IncN plasmid pMUR050. Molecular analysis of the plasmid and of the armA locus confirmed the spread of this resistance determinant...
  6. pmc Klebsiella pneumoniae sequence type 11 from companion animals bearing ArmA methyltransferase, DHA-1 β-lactamase, and QnrB4
    Laura Hidalgo
    Department of Animal Health and VISAVET, Universidad Complutense de Madrid, Madrid, Spain
    Antimicrob Agents Chemother 57:4532-4. 2013
    ..This first report of the ArmA methyltransferase in pets illustrates their importance as a reservoir for human multidrug-resistant K. pneumoniae. ..
  7. pmc Fitness cost and interference of Arm/Rmt aminoglycoside resistance with the RsmF housekeeping methyltransferases
    Belen Gutierrez
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain
    Antimicrob Agents Chemother 56:2335-41. 2012
    ....
  8. pmc Fluoroquinolone efflux in Streptococcus suis is mediated by SatAB and not by SmrA
    Jose Antonio Escudero
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain
    Antimicrob Agents Chemother 55:5850-60. 2011
    ..Chromosomal integration in Bacillus is a novel method for studying efflux pumps from Gram-positive bacteria, which enabled us to demonstrate the possible role of SatAB, and not SmrA, in fluoroquinolone efflux in S. suis...
  9. pmc Haemophilus influenzae clinical isolates with plasmid pB1000 bearing blaROB-1: fitness cost and interspecies dissemination
    Alvaro San Millan
    Departamento de Sanidad Animal, Universidad Complutense de Madrid, 28040 Madrid, Spain
    Antimicrob Agents Chemother 54:1506-11. 2010
    ..multocida is the only member of this family that can colonize both humans and animals, we propose that P. multocida is the vehicle for the transport of pB1000 between animal- and human-adapted members of the Pasteurellaceae...
  10. pmc SatR is a repressor of fluoroquinolone efflux pump SatAB
    Jose Antonio Escudero
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain
    Antimicrob Agents Chemother 57:3430-3. 2013
    ..satR is cotranscribed with satAB, and its interruption entails the overexpression of the pump, leading to a clinically relevant increase in resistance to fluoroquinolones...
  11. doi request reprint Association of the novel aminoglycoside resistance determinant RmtF with NDM carbapenemase in Enterobacteriaceae isolated in India and the UK
    Laura Hidalgo
    Department of Animal Health and VISAVET, Universidad Complutense de Madrid, Madrid, Spain
    J Antimicrob Chemother 68:1543-50. 2013
    ..We sought genes encoding these enzymes in isolates highly resistant (MIC >200 mg/L) to gentamicin and amikacin from an Indian hospital and we additionally screened for the novel RmtF enzyme in 132 UK isolates containing NDM...
  12. pmc Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1
    Alvaro San Millan
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain
    Antimicrob Agents Chemother 51:2260-4. 2007
    ..Pulsed-field gel electrophoresis was applied for the first time to H. parasuis and showed that beta-lactam resistance is due to clonal spread of a resistant strain, BB1018, bearing pB1000...
  13. doi request reprint Contribution of ROB-1 and PBP3 mutations to the resistance phenotype of a β-lactamase-positive amoxicillin/clavulanic acid-resistant Haemophilus influenzae carrying plasmid pB1000 in Italy
    Alvaro San Millan
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain
    J Antimicrob Chemother 66:96-9. 2011
    ..Here, we explore the presence of ROB-1 in Italy and investigate the relative contribution of penicillin-binding protein 3 (PBP3) mutations and ROB-1 to the β-lactam resistance phenotype in H. influenzae...
  14. ncbi request reprint Susceptibility of Listeria monocytogenes to antimicrobial peptides
    Emilia López-Solanilla
    Departamento de Biotecnologia, ETS de Ingenieros Agrónomos, Universidad Politecnica, 28040, Madrid, Spain
    FEMS Microbiol Lett 226:101-5. 2003
    ..These data indicate that the thermoregulated transcription factor PrfA controls the expression of bacterial products that influence the susceptibility or resistance to some antimicrobial peptides...
  15. ncbi request reprint First identification of Salmonella Urbana and Salmonella Ouakam in humans in Africa
    Courage Kosi Setsoafia Saba
    Facultad de Veterinaria, Universidad Complutense de Madrid, Spain
    J Infect Dev Ctries 7:691-5. 2013
    ..This has made it difficult to estimate the actual burden of salmonellosis, especially in Africa. This study was conducted in a neglected Northern Region of Ghana where there are no previous data on Salmonella serotypes...
  16. pmc First characterization of fluoroquinolone resistance in Streptococcus suis
    Jose Antonio Escudero
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain
    Antimicrob Agents Chemother 51:777-82. 2007
    ..Resistance is the consequence of single point mutations in the QRDRs of ParC and GyrA and is not due to clonal spread of resistant strains or horizontal gene transfer with other bacteria...
  17. pmc Hpt, a bacterial homolog of the microsomal glucose- 6-phosphate translocase, mediates rapid intracellular proliferation in Listeria
    Isabel Chico-Calero
    Grupo de Patogénesis Molecular Bacteriana, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain
    Proc Natl Acad Sci U S A 99:431-6. 2002
    ..It is also a clear example of how adaptation to intracellular parasitism by microbial pathogens involves mimicry of physiological mechanisms of their eukaryotic host cells...
  18. doi request reprint Characterization of a recombinant transferrin-binding protein A (TbpA) fragment from Haemophilus parasuis serovar 5
    Sonia Martinez
    Departamento de Sanidad Animal, Facultad de Veterinaria, Unidad de Microbiologia e Inmunologia, Universidad de Leon, Leon, Spain
    FEMS Microbiol Lett 307:142-50. 2010
    ..parasuis, and a significant bactericidal activity was also detected. Therefore, this rTbpA fragment induces an immunological response and might be useful as an antigen for vaccination against Glässer's disease...
  19. pmc Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids
    Alvaro San Millan
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain
    Antimicrob Agents Chemother 53:3399-404. 2009
    ..multocida but highly unstable in E. coli. In conclusion, bla(ROB-1) is responsible for beta-lactam resistance in P. multocida in Spain. Coexistence and the spread of small plasmids are used by P. multocida to become multiresistant...
  20. ncbi request reprint A spontaneous genomic deletion in Listeria ivanovii identifies LIPI-2, a species-specific pathogenicity island encoding sphingomyelinase and numerous internalins
    Gustavo Domínguez-Bernal
    Grupo de Patogénesis Molecular Bacteriana, Facultad de Veterinaria, Universidad Complutense, Madrid, Spain
    Mol Microbiol 59:415-32. 2006
    ..LIPI-2 is conserved in L. ivanovii ssp. ivanovii and londoniensis, suggesting an early acquisition during the species' evolution. LIPI-2 is likely to play an important role in the pathogenic and host tropism of L. ivanovii...
  21. pmc ArmA methyltransferase in a monophasic Salmonella enterica isolate from food
    Sophie A Granier
    Anses, Laboratoire de Sécurité des Aliments, Maisons Alfort, France
    Antimicrob Agents Chemother 55:5262-6. 2011
    ..Further surveillance in food-borne bacteria will be crucial to determine the role of food in the spread of 16S rRNA methyltransferase genes worldwide...