Mario David Cordero

Summary

Affiliation: Universidad Pablo de Olavide
Country: Spain

Publications

  1. doi [Low levels of serotonin in serum correlates with severity of fibromyalgia]
    Mario David Cordero
    Centro Andaluz de Biologia del Desarrollo CABD, Universidad Pablo de Olavide CSIC y Centro de Investigación Biomédica en Red de Enfermedades Raras CIBERER, ISCIII, Sevilla, Espana
    Med Clin (Barc) 135:644-6. 2010
  2. pmc Autophagy in periodontitis patients and gingival fibroblasts: unraveling the link between chronic diseases and inflammation
    Pedro Bullon
    Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche Sezione Biochimica, Universita Politecnica delle Marche, Via Ranieri, 65, Ancona, 60100, Italia
    BMC Med 10:122. 2012
  3. doi Oral coenzyme Q10 supplementation improves clinical symptoms and recovers pathologic alterations in blood mononuclear cells in a fibromyalgia patient
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo, Universidad Pablo de Olavide CSIC Junta de Andalucía and Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII, Seville, Spain
    Nutrition 28:1200-3. 2012
  4. pmc Oxidative stress correlates with headache symptoms in fibromyalgia: coenzyme Q₁₀ effect on clinical improvement
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo, Universidad Pablo de Olavide CSIC Junta de Andalucía and Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII, Sevilla, Spain
    PLoS ONE 7:e35677. 2012
  5. doi Coenzyme Q10 in salivary cells correlate with blood cells in Fibromyalgia: improvement in clinical and biochemical parameter after oral treatment
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo, Universidad Pablo de Olavide CSIC Junta de Andalucía, ISCIII, Sevilla, Spain
    Clin Biochem 45:509-11. 2012
  6. pmc Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathogenesis of the disease
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo CABD, Universidad Pablo de Olavide CSIC, Ctra, de Utrera, km, 1, ISCIII, Sevilla 41013, Spain
    Arthritis Res Ther 12:R17. 2010
  7. pmc Clinical symptoms in fibromyalgia are better associated to lipid peroxidation levels in blood mononuclear cells rather than in plasma
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo, Universidad Pablo de Olavide CSIC and Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII, Sevilla, Spain
    PLoS ONE 6:e26915. 2011
  8. doi Mitochondrial dysfunction in skin biopsies and blood mononuclear cells from two cases of fibromyalgia patients
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo, CABD, Universidad Pablo de Olavide CSIC and Centro de Investigación Biomédica en Red de Enfermedades Raras, CIBERER, ISCIII, Sevilla, Spain
    Clin Biochem 43:1174-6. 2010
  9. doi Coenzyme Q(10): a novel therapeutic approach for Fibromyalgia? case series with 5 patients
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo CABD, Universidad Pablo de Olavide CSIC, Sevilla, Spain
    Mitochondrion 11:623-5. 2011
  10. doi Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs
    Mario David Cordero
    Departamento Citología e Histología Normal y Patológica, Facultad de Medicina, Universidad de Sevilla, Sevilla, Spain
    Anticancer Drugs 21:932-44. 2010

Collaborators

Detail Information

Publications16

  1. doi [Low levels of serotonin in serum correlates with severity of fibromyalgia]
    Mario David Cordero
    Centro Andaluz de Biologia del Desarrollo CABD, Universidad Pablo de Olavide CSIC y Centro de Investigación Biomédica en Red de Enfermedades Raras CIBERER, ISCIII, Sevilla, Espana
    Med Clin (Barc) 135:644-6. 2010
    ..The aim of the present study was to assess the correlation levels between low levels of serotonin and severity of symptoms in FM...
  2. pmc Autophagy in periodontitis patients and gingival fibroblasts: unraveling the link between chronic diseases and inflammation
    Pedro Bullon
    Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche Sezione Biochimica, Universita Politecnica delle Marche, Via Ranieri, 65, Ancona, 60100, Italia
    BMC Med 10:122. 2012
    ..Thus it is important to study the role of autophagy in the pathophysiology of periodontitis...
  3. doi Oral coenzyme Q10 supplementation improves clinical symptoms and recovers pathologic alterations in blood mononuclear cells in a fibromyalgia patient
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo, Universidad Pablo de Olavide CSIC Junta de Andalucía and Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII, Seville, Spain
    Nutrition 28:1200-3. 2012
    ..Our results suggest that CoQ10 could be an alternative therapeutic approach for FM...
  4. pmc Oxidative stress correlates with headache symptoms in fibromyalgia: coenzyme Q₁₀ effect on clinical improvement
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo, Universidad Pablo de Olavide CSIC Junta de Andalucía and Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII, Sevilla, Spain
    PLoS ONE 7:e35677. 2012
    ..The effects of oral coenzyme Q(10) (CoQ(10)) supplementation on biochemical markers and clinical improvement were also evaluated...
  5. doi Coenzyme Q10 in salivary cells correlate with blood cells in Fibromyalgia: improvement in clinical and biochemical parameter after oral treatment
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo, Universidad Pablo de Olavide CSIC Junta de Andalucía, ISCIII, Sevilla, Spain
    Clin Biochem 45:509-11. 2012
    ..We have determined Coenzyme Q(10) (CoQ(10)) levels in salivary cells (SCs) and mononuclear blood cells (BMCs) from Fibromyalgia (FM), and we study the influence of oral CoQ(10) supplementation on cells levels and clinical symptoms...
  6. pmc Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathogenesis of the disease
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo CABD, Universidad Pablo de Olavide CSIC, Ctra, de Utrera, km, 1, ISCIII, Sevilla 41013, Spain
    Arthritis Res Ther 12:R17. 2010
    ..Furthermore, the role of mitochondria in the redox imbalance reported in fibromyalgia also is controversial. We undertook this study to investigate the role of mitochondrial dysfunction, oxidative stress, and mitophagy in fibromyalgia...
  7. pmc Clinical symptoms in fibromyalgia are better associated to lipid peroxidation levels in blood mononuclear cells rather than in plasma
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo, Universidad Pablo de Olavide CSIC and Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII, Sevilla, Spain
    PLoS ONE 6:e26915. 2011
    ..We examined lipid peroxidation (LPO) in blood mononuclear cells (BMCs) and plasma, as a marker of oxidative damage, and its association to clinical symptoms in Fibromyalgia (FM) patients...
  8. doi Mitochondrial dysfunction in skin biopsies and blood mononuclear cells from two cases of fibromyalgia patients
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo, CABD, Universidad Pablo de Olavide CSIC and Centro de Investigación Biomédica en Red de Enfermedades Raras, CIBERER, ISCIII, Sevilla, Spain
    Clin Biochem 43:1174-6. 2010
    ..The aim of this study was to analyze CoQ(10) levels, mitochondrial dysfunction, and oxidative stress in plasma, blood mononuclear cells, and skin biopsies from FM patients...
  9. doi Coenzyme Q(10): a novel therapeutic approach for Fibromyalgia? case series with 5 patients
    Mario D Cordero
    Centro Andaluz de Biologia del Desarrollo CABD, Universidad Pablo de Olavide CSIC, Sevilla, Spain
    Mitochondrion 11:623-5. 2011
    ..Determination of deficiency and consequent supplementation in FM may result in clinical improvement. Further analysis involving more scientifically rigorous methodology will be required to confirm this observation...
  10. doi Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs
    Mario David Cordero
    Departamento Citología e Histología Normal y Patológica, Facultad de Medicina, Universidad de Sevilla, Sevilla, Spain
    Anticancer Drugs 21:932-44. 2010
    ..In conclusion, based on the capacity of generating ROS and inhibiting antioxidants in tumor cells, amitriptyline emerges as a promising new drug to be tested for anticancer therapy...
  11. doi Mitochondrial dysfunction promoted by Porphyromonas gingivalis lipopolysaccharide as a possible link between cardiovascular disease and periodontitis
    Pedro Bullon
    Department of Periodontology, Dental School, University of Sevilla, Sevilla, Spain
    Free Radic Biol Med 50:1336-43. 2011
    ..In conclusion, mitochondrial dysfunction could represent a possible link to understanding the interrelationships between two prominent inflammatory diseases: periodontitis and CVD...
  12. doi [Mitochondrial dysfunction in fibromyalgia and its implication in the pathogenesis of disease]
    Mario David Cordero
    Centro Andaluz de Biologia del Desarrollo, Universidad Pablo de Olavide CSIC y Centro de Investigación Biomédica en Red de Enfermedades Raras, Instituto Carlos III, Sevilla, Espana
    Med Clin (Barc) 136:252-6. 2011
    ....
  13. ncbi The apoptotic microtubule network preserves plasma membrane integrity during the execution phase of apoptosis
    José A Sánchez-Alcázar
    Centro Andaluz de Biologia del Desarrollo, Universidad Pablo de Olavide CSIC, Carretera de Utrera Km 1, Sevilla, 41013, Spain
    Apoptosis 12:1195-208. 2007
    ..We propose that apoptotic microtubule network is required to maintain plasma membrane integrity during the execution phase of apoptosis...
  14. ncbi Coenzyme Q deficiency triggers mitochondria degradation by mitophagy
    Angeles Rodriguez-Hernandez
    Centro Andaluz de Biologia del Desarrollo CABD, and Centro de Investigación Biomédica en Red Enfermedades Raras, Instituto de Salud Carlos III, Universidad Pablo de Olavide Consejo Superior de Investigaciones Científicas, Sevilla, Spain
    Autophagy 5:19-32. 2009
    ....
  15. ncbi Coenzyme Q10 and alpha-tocopherol protect against amitriptyline toxicity
    Mario D Cordero
    Centro Andaluz de Biología de Desarrollo CABD, Universidad Pablo de Olavide CSIC, and Centro de Investigación Biomédica en Red de Enfermedades Raras CIBERER, ISCIII, Sevilla, Spain
    Toxicol Appl Pharmacol 235:329-37. 2009
    ..Amitriptyline significantly increased embryonic cell death and apoptosis rate, and both antioxidants provided a significant protection against amitriptyline embryotoxicity...
  16. ncbi Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis
    José M López-Martín
    Centro Andaluz de Biologia del Desarrollo, Universidad Pablo de Olavide CSIC, 41013 Sevilla, Spain
    Hum Mol Genet 16:1091-7. 2007
    ..Moreover, we demonstrate that CoQ(10) deficiency in addition to the bioenergetics defect also impairs de novo pyrimidine synthesis, which may contribute to the pathogenesis of the disease...