Juan M Bellon

Summary

Affiliation: Universidad de Alcal
Country: Spain

Publications

  1. ncbi request reprint [Polypropylene and polydioxanone show similar biomechanical efficacy in midline closure]
    Juan M Bellon
    Departamento de Cirugia, Facultad de Medicina, Universidad de Alcala, Alcala de Henares, Madrid, Spain
    Cir Esp 78:377-81. 2005
  2. doi request reprint Postimplant intraperitoneal behavior of collagen-based meshes followed by laparoscopy
    Juan M Bellon
    Department of Surgery, Faculty of Medicine, University of Alcala, Networking Research Centre on Bioengineering, Biomaterials and Nanomedicine CIBER BBN, Alcala de Henares, Ctra Madrid Barcelona, Km 33, 600, 28871, Madrid, Spain
    Surg Endosc 26:27-35. 2012
  3. ncbi request reprint [Abdominal wall closure in laparotomy]
    Juan M Bellón-Caneiro
    Departamento de Cirugia, Facultad de Medicina, Universidad de Alcala, Madrid, Espana
    Cir Esp 77:114-23. 2005
  4. ncbi request reprint [Composite prostheses for the repair of abdominal wall defects: comparative study of physical and/or chemical barriers]
    Juan M Bellon
    Departamento de Cirugia, Facultad de Medicina, Universidad de Alcala, Madrid, Espana
    Cir Esp 77:351-6. 2005
  5. ncbi request reprint Influence of the structure of new generation prostheses on shrinkage after implant in the abdominal wall
    J M Bellon
    Department of Surgery, Faculty of Medicine, University of Alcala, Ctra N II, Km 33 600, 28871 Alcala de Henares, Madrid, Spain
    J Biomed Mater Res B Appl Biomater 78:340-6. 2006
  6. ncbi request reprint Efficiency of 4% icodextrin in preventing adhesions to spiral tacks used to fix intraperitoneal prostheses
    J M Bellon
    Department of Surgery, Faculty of Medicine, Alcala University, Alcala De Henares Madrid, Spain
    Eur Surg Res 38:458-63. 2006
  7. ncbi request reprint [Real-time monitoring of the peritoneal behavior of composite prostheses by sequential laparoscopy: applicability in ventral hernia repair]
    Juan M Bellon
    Departamento de Cirugia, Facultad de Medicina, Universidad de Alcala, Alcala de Henares, Madrid, Espana
    Cir Esp 82:290-6. 2007
  8. ncbi request reprint Peritoneal effects of prosthetic meshes used to repair abdominal wall defects: monitoring adhesions by sequential laparoscopy
    Juan M Bellon
    Department of Surgery, Alcala University, Madrid, Spain
    J Laparoendosc Adv Surg Tech A 17:160-6. 2007
  9. ncbi request reprint Partially absorbable meshes for hernia repair offer advantages over nonabsorbable meshes
    Juan M Bellon
    Department of Surgery, Alcala University, Ctra Madrid Barcelona, Km 33 600, 28871 Alcala de Henares, Madrid, Spain
    Am J Surg 194:68-74. 2007
  10. ncbi request reprint [Biological factors involved in the genesis of incisional hernia]
    Juan M Bellon
    Departamento de Cirugia, Facultad de Medicina, Universidad de Alcala, Madrid, Espana
    Cir Esp 83:3-7. 2008

Collaborators

  • Julia Bujan
  • G Pascual
  • M Rodriguez
  • A C Martin
  • Alberto Gallardo
  • CATHERINE M KIELTY
  • Verónica Gómez-Gil
  • Natalio Garcia-Honduvilla
  • Francisco García-Esteo
  • Hipólito J Durán
  • Juan Manuel Bellón-Caneiro
  • Juan M Bellón-Caneiro
  • Bárbara Pérez-Köhler
  • Alberto Cifuentes
  • Cristina Escudero
  • Belén Domínguez
  • Francisco Minguela
  • Julio San-Román
  • Natalia Serrano-Amarilla
  • Julia Buján-Varela
  • Esmeralda Carnicer-Escusol
  • Marta Rodríguez-Mancheño

Detail Information

Publications45

  1. ncbi request reprint [Polypropylene and polydioxanone show similar biomechanical efficacy in midline closure]
    Juan M Bellon
    Departamento de Cirugia, Facultad de Medicina, Universidad de Alcala, Alcala de Henares, Madrid, Spain
    Cir Esp 78:377-81. 2005
    ..This study was designed to evaluate the biomechanical resistance of midline closure using the same surgical technique but two different types of suture material, a long-lasting absorbable material and a non-absorbable material...
  2. doi request reprint Postimplant intraperitoneal behavior of collagen-based meshes followed by laparoscopy
    Juan M Bellon
    Department of Surgery, Faculty of Medicine, University of Alcala, Networking Research Centre on Bioengineering, Biomaterials and Nanomedicine CIBER BBN, Alcala de Henares, Ctra Madrid Barcelona, Km 33, 600, 28871, Madrid, Spain
    Surg Endosc 26:27-35. 2012
    ..This study was designed to assess the intraperitoneal behavior of three of these biomeshes, mainly in terms of their susceptibility to adhesion formation...
  3. ncbi request reprint [Abdominal wall closure in laparotomy]
    Juan M Bellón-Caneiro
    Departamento de Cirugia, Facultad de Medicina, Universidad de Alcala, Madrid, Espana
    Cir Esp 77:114-23. 2005
    ..One such method could perhaps be the use of a biomaterial to support and strengthen conventional sutures...
  4. ncbi request reprint [Composite prostheses for the repair of abdominal wall defects: comparative study of physical and/or chemical barriers]
    Juan M Bellon
    Departamento de Cirugia, Facultad de Medicina, Universidad de Alcala, Madrid, Espana
    Cir Esp 77:351-6. 2005
    ..This study was designed to evaluate how the composition of this second component affects the biological behavior of the biomaterial and the formation of adhesions...
  5. ncbi request reprint Influence of the structure of new generation prostheses on shrinkage after implant in the abdominal wall
    J M Bellon
    Department of Surgery, Faculty of Medicine, University of Alcala, Ctra N II, Km 33 600, 28871 Alcala de Henares, Madrid, Spain
    J Biomed Mater Res B Appl Biomater 78:340-6. 2006
    ..Reduced DM shrinkage was linked to decreased myofibroblast numbers 2 weeks postimplant...
  6. ncbi request reprint Efficiency of 4% icodextrin in preventing adhesions to spiral tacks used to fix intraperitoneal prostheses
    J M Bellon
    Department of Surgery, Faculty of Medicine, Alcala University, Alcala De Henares Madrid, Spain
    Eur Surg Res 38:458-63. 2006
    ..This study was designed to evaluate the extent of adhesion formation to prostheses fixed with spiral tacks and to establish whether the use of Ringer's lactate or icodextrin could prevent these adhesions...
  7. ncbi request reprint [Real-time monitoring of the peritoneal behavior of composite prostheses by sequential laparoscopy: applicability in ventral hernia repair]
    Juan M Bellon
    Departamento de Cirugia, Facultad de Medicina, Universidad de Alcala, Alcala de Henares, Madrid, Espana
    Cir Esp 82:290-6. 2007
    ..This study was designed to assess the behavior at the peritoneal interface of several composite prostheses using sequential laparoscopy to monitor the real-time adhesion formation process...
  8. ncbi request reprint Peritoneal effects of prosthetic meshes used to repair abdominal wall defects: monitoring adhesions by sequential laparoscopy
    Juan M Bellon
    Department of Surgery, Alcala University, Madrid, Spain
    J Laparoendosc Adv Surg Tech A 17:160-6. 2007
    ..This interface is often a site of complications such as intestinal obstruction or fistulas due to adhesions. The aim of this study was to follow the process of adhesion formation in several prosthetic materials by sequential laparoscopy...
  9. ncbi request reprint Partially absorbable meshes for hernia repair offer advantages over nonabsorbable meshes
    Juan M Bellon
    Department of Surgery, Alcala University, Ctra Madrid Barcelona, Km 33 600, 28871 Alcala de Henares, Madrid, Spain
    Am J Surg 194:68-74. 2007
    ..The aim of this study was to establish whether new prosthetic materials with absorbable components, designed to reduce the amount of foreign material in abdominal wall repair, offer advantages over the conventional polypropylene meshes...
  10. ncbi request reprint [Biological factors involved in the genesis of incisional hernia]
    Juan M Bellon
    Departamento de Cirugia, Facultad de Medicina, Universidad de Alcala, Madrid, Espana
    Cir Esp 83:3-7. 2008
    ..These features suggest the need for a biomaterial to strengthen laparotomy closures, especially midline closures, in high-risk patients and/or in those where wound healing is compromised...
  11. ncbi request reprint [Biological prostheses: indications and usefulness in the repair of abdominal wall defect]
    Juan M Bellon
    Departamento de Cirugia, Facultad de Medicina Universidad de Alcalá, Alcala De Henares Madrid, Espana
    Cir Esp 83:283-9. 2008
    ..These implants are composed of collagen of animal (usually porcine) or human origin. They should be acellular and fully biocompatible so that they induce a minimal foreign body reaction and immune response...
  12. doi request reprint Comparing the behavior of different polypropylene meshes (heavy and lightweight) in an experimental model of ventral hernia repair
    J M Bellon
    Department of Surgery, Faculty of Medicine, Networking Research Center on Bioengineering, Biomaterials and Nanomedicine CIBER BBN, Alcala University, Alcala de Henares, Madrid, Spain
    J Biomed Mater Res B Appl Biomater 89:448-55. 2009
    ..Compared with HW, LW prostheses have the benefit that less foreign material was implanted, preserving the elasticity of the recipient host tissue...
  13. doi request reprint Postimplant behavior of lightweight polypropylene meshes in an experimental model of abdominal hernia
    Juan M Bellon
    Department of Surgery, Faculty of Medicine, Networking Research Center on Bioengineering, Biomaterials and Nanomedicine CIBER BBN, Alcala University, Alcala de Henares, Madrid, Spain
    J Invest Surg 21:280-7. 2008
    ..This study was designed to assess the biological and biomechanical behavior of these prostheses to establish whether they offer any advantages over nonabsorbable lightweight polypropylene prostheses...
  14. doi request reprint [Role of the new lightweight prostheses in improving hernia repair]
    Juan M Bellon
    Facultad de Medicina, Departamento de Cirugía CIBER en Bioingeniería, Biomateriales y Nanomedicina, Universidad de Alcala, Alcala de Henares, Madrid, Espana
    Cir Esp 85:268-73. 2009
    ..However, further studies are still needed to achieve the ideal balance between material density and pore size. These two factors will determine the behaviour of these new prosthetic designs...
  15. ncbi request reprint [Proposal for a new classification of prostheses used in the repair of abdominal wall hernial defects]
    Juan Manuel Bellón
    Departamento de Cirugia, Facultad de Medicina, Universidad de Alcala, Alcala de Henares, Madrid, Spain
    Cir Esp 78:148-51. 2005
    ..The new classification scheme we propose takes into account the type of prosthesis, its components, and its ideal site of placement in the abdominal wall...
  16. ncbi request reprint [Use of a composite prosthesis (PL-PU99) versus a biological prosthesis (Surgisis) in an experimental model of temporary abdominal closure]
    Juan Manuel Bellón-Caneiro
    Departamento de Cirugia, Universidad de Alcala, Alcala de Henares, Madrid, Spain
    Cir Esp 78:103-8. 2005
    ..This allows normal intra-abdominal pressure to be maintained and the fascial edges to be preserved for subsequent definitive closure...
  17. pmc Fibroblasts from the transversalis fascia of young patients with direct inguinal hernias show constitutive MMP-2 overexpression
    J M Bellon
    Department of Morphological Sciences and Surgery, Faculty of Medicine, University of Alcala, Madrid, Spain
    Ann Surg 233:287-91. 2001
    ..To determine the expression pattern of certain metalloproteinases (MMPs) known to be involved in the degradation of the extracellular matrix in cultured fibroblasts from the transversalis fascia (TF) of patients with inguinal hernia...
  18. ncbi request reprint In vitro interaction of bacteria with polypropylene/ePTFE prostheses
    J M Bellon
    Department of Morphological Sciences and Surgery, Faculty of Medicine, University of Alcala de Henares, Madrid, Spain
    Biomaterials 22:2021-4. 2001
    ..The latter areas are of difficult access to defence agents...
  19. ncbi request reprint Use of composite prostheses in the repair of defects in the abdominal wall: prosthetic behaviour at the peritoneum
    J M Bellon
    Department of Morphological Sciences and Surgery, Faculty of Medicine, University of Alcala, Madrid, Spain
    Eur J Surg 167:666-71. 2001
    ..To compare the behaviour of two composite biomaterials in rabbit peritoneum...
  20. ncbi request reprint Healing process induced by three composite prostheses in the repair of abdominal wall defects
    Juan M Bellon
    Department of Morphological Sciences and Surgery Surgical Research Laboratory, Faculty of Medicine, University of Alcala, Madrid, Spain
    J Biomed Mater Res 63:182-90. 2002
    ....
  21. ncbi request reprint Evaluation of a new composite prosthesis (PL-PU99) for the repair of abdominal wall defects in terms of behavior at the peritoneal interface
    Juan M Bellon
    Department of Morphological Sciences and Surgery, Faculty of Medicine, University of Alcala, Ctra Madrid Barcelona, Km 33 6, 28871 Alcala de Henares, Madrid, Spain
    World J Surg 26:661-6. 2002
    ....
  22. ncbi request reprint The structure of a biomaterial rather than its chemical composition modulates the repair process at the peritoneal level
    Juan M Bellon
    Department of Morphological Sciences and Surgery Surgical Research Laboratory, Faculty of Medicine, University of Alcala, Crta Madrid Barcelona, Km 33 6, 28871 Alcala de Henares, Madrid, Spain
    Am J Surg 184:154-9. 2002
    ..This study was designed to establish whether the spatial structure of a prosthesis conditions its behavior at the peritoneal level...
  23. ncbi request reprint Composite prostheses used to repair abdominal wall defects: physical or chemical adhesion barriers?
    J M Bellon
    Department of Surgery, Faculty of Medicine, Alcala University, Ctra N II, Km 33 600, 28871 Alcala de Henares, Madrid, Spain
    J Biomed Mater Res B Appl Biomater 74:718-24. 2005
    ..However, the prostheses with chemical barriers differed in their effectiveness at preventing adhesions. Overall, the best results were obtained with the PP + PU composite...
  24. ncbi request reprint Improved biomechanical resistance using an expanded polytetrafluoroethylene composite-structure prosthesis
    Juan M Bellon
    Department of Surgery, Faculty of Medicine, Alcala University, Ctra N II, Km 33 600, 28871 Alcala de Henares, Madrid, Spain
    World J Surg 28:461-5. 2004
    ..71 vs. 14.11 +/- 3.71 N). Our findings suggest that the use of a reticular and a laminar ePTFE layer in the same prosthesis leads to better repair and biomechanical behavior compared to the use of a single-structure laminar implant...
  25. ncbi request reprint Temporary closure of the abdomen using a new composite prosthesis (PL-PU99)
    Juan M Bellon
    Departamento de Cirugia, Facultad de Medicina, Universidad de Alcala, Campus Universitario, Ctra Madrid Barcelona Km 33 600, E 28871 Alcala de Henares, Madrid, Spain
    Am J Surg 188:314-20. 2004
    ..Temporary abdominal wound closure is sometimes desirable when tension-free approximation of the wound edges is impractical or when reexploration is planned...
  26. ncbi request reprint Tissue integration and biomechanical behaviour of contaminated experimental polypropylene and expanded polytetrafluoroethylene implants
    J M Bellon
    Department of Surgery, Faculty of Medicine, University of Alcala, Carretera, Madrid Barcelona Km 33 6, E 28871 Alcala de Henares, Madrid, Spain
    Br J Surg 91:489-94. 2004
    ..The aim of this study was to compare the behaviour of two biomaterials contaminated with Staphylococcus aureus or Staphylococcus epidermidis, used to repair abdominal wall defects...
  27. ncbi request reprint Composite prostheses for the repair of abdominal wall defects: effect of the structure of the adhesion barrier component
    J M Bellon
    Department of Surgery, Faculty of Medicine, Alcala University, Ctra N II, Km 33 600, 28871, Alcala de Henares, Madrid, Spain
    Hernia 9:338-43. 2005
    ..05). The tested biomaterials induced an optimal recipient tissue infiltration. Least adhesion formation was observed on the PP + h implants. This suggests that the second component, although reabsorbable, should be smooth in structure...
  28. doi request reprint Early tissue incorporation and collagen deposition in lightweight polypropylene meshes: bioassay in an experimental model of ventral hernia
    Gemma Pascual
    Department of Medical Specialities, Faculty of Medicine, University of Alcala, Alcala de Henares, Madrid, Spain
    Surgery 144:427-35. 2008
    ....
  29. doi request reprint The long-term behavior of lightweight and heavyweight meshes used to repair abdominal wall defects is determined by the host tissue repair process provoked by the mesh
    Gemma Pascual
    Department of Surgery and Medical Specialities, University of Alcala, Alcala de Henares, Madrid, Spain
    Surgery 152:886-95. 2012
    ..This study compares the long-term (3 and 6 months) behavior of meshes of different pore size (HW compared with LW) and composition (PP compared with PTFE)...
  30. ncbi request reprint Midline abdominal wall closure: a new prophylactic mesh concept
    Juan M Bellon
    Department of Surgery, Faculty of Medicine, Alcala University, Ctra Madrid Barcelona, Km 33, 600, Alcala de Henares, 29971 Madrid, Spain
    J Am Coll Surg 203:490-7. 2006
    ..This study was designed to reinforce the midline laparotomy closure by including a new prosthetic design between the edges of the surgical wound...
  31. pmc Repair of abdominal wall defects with biodegradable laminar prostheses: polymeric or biological?
    Gemma Pascual
    Department of Medical Specialties, Networking Research Center on Bioengineering, Biomaterials and Nanomedicine CIBER BBN, Faculty of Medicine, Alcala University, Alcala de Henares, Madrid, Spain
    PLoS ONE 7:e52628. 2012
    ..This study was designed to assess the host tissue's incorporation of collagen bioprostheses and a synthetic absorbable prosthesis...
  32. doi request reprint Effects of collagen prosthesis cross-linking on long-term tissue regeneration following the repair of an abdominal wall defect
    Gemma Pascual
    Department of Medical Specialities, University of Alcala, Madrid, Spain
    Wound Repair Regen 20:402-13. 2012
    ....
  33. doi request reprint Chemical adhesion barriers: do they affect the intraperitoneal behavior of a composite mesh?
    Marta Rodriguez
    Department of Surgery, Faculty of Medicine, Networking Research Center on Bioengineering, Biomaterials and Nanomedicine, University of Alcala, Madrid, Spain
    J Invest Surg 24:115-22. 2011
    ..This study was designed to laparoscopically examine the real-time behavior of three composite meshes incorporating a chemical adhesion barrier when placed in contact with the visceral peritoneum...
  34. doi request reprint Peritoneal adhesion formation and reformation tracked by sequential laparoscopy: optimizing the time point for adhesiolysis
    Verónica Gómez-Gil
    Department of Medical Specialities, Faculty of Medicine, Networking Research Center on Bioengineering, Biomaterials and Nanomedicine, University of Alcala, Alcala de Henares, Madrid, Spain
    Surgery 147:378-91. 2010
    ..Using a rabbit adhesiogenesis model, this study assessed the efficacy of adhesiolysis and examined how this relates to the tissue composition of adhesions at the time of lysis...
  35. doi request reprint Characterizing omental adhesions by culturing cells isolated from a novel in vivo adhesion model
    Verónica Gómez-Gil
    Department of Medical Specialities, Faculty of Medicine, University of Alcala, Networking Research Centre on Biomaterials and Nanomedicine CIBER BBN, Madrid, Spain
    Wound Repair Regen 17:51-61. 2009
    ..The other adhesions are fibrous with large amounts of collagen and comprised mainly of myofibroblasts conferring less compliance to this tissue...
  36. ncbi request reprint Muscle-derived stem cells used to treat skin defects prevent wound contraction and expedite reepithelialization
    Julia Bujan
    Department of Medical Specialities, Faculty of Medicine, University of Alcala, Alcala de Henares, Madrid, Spain
    Wound Repair Regen 14:216-23. 2006
    ..Reepithelialization occurred as epidermal tongues of fusiform cells. Our findings indicate that the use of autologous stem cells on skin wounds expedites and improves the organism's natural healing process...
  37. ncbi request reprint New approach to improving endothelial preservation in cryopreserved arterial substitutes
    Gemma Pascual
    Department of Medical Specialities, Faculty of Medicine, University of Alcala, E 28871 Alcala de Henares, Madrid, Spain
    Cryobiology 48:62-71. 2004
    ..This method gives rise to best endothelial cell viability and cover values, with obvious benefits for subsequent grafting...
  38. doi request reprint Involvement of transforming growth factor-β3 and betaglycan in the cytoarchitecture of postoperative omental adhesions
    Verónica Gómez-Gil
    Department of Medicine and Medical Specialties, Networking Research Center on Bioengineering, Biomaterials and Nanomedicine CIBER BBN, Faculty of Medicine and Health Sciences, University of Alcala, Alcala de Henares, Madrid, Spain
    J Surg Res 187:699-711. 2014
    ..Here, we address the influence of transforming growth factor (TGF)-β3 and betaglycan in this response, in relation to TGF-β1, in an adhesiogenic rabbit model...
  39. ncbi request reprint Engineering conduits to resemble natural vascular tissue
    Julia Bujan
    Department of Medical Specialities, Faculty of Medicine, University of Alcala, Alcala de Henares, Madrid, Spain
    Biotechnol Appl Biochem 39:17-27. 2004
    ..There is also no doubt that developments in engineered arterial grafts made of natural biomaterials colonized with cells harvested from the recipient patient are drawing us closer and closer to achieving the living graft...
  40. ncbi request reprint Expression of elastic components in healthy and varicose veins
    Julia Bujan
    Department of Morphological Sciences and Surgery, Faculty of Medicine, University of Alcala, Ctra Madrid Barcelona km 33 6, 28871 Madrid, Spain
    World J Surg 27:901-5. 2003
    ..Our findings suggest that the development of the varicose condition involves a restructuring of the elastic component of the vein wall, perhaps as a consequence of changes in the transcription mechanisms of muscle layer cells...
  41. pmc Behaviour of a new composite mesh for the repair of full-thickness abdominal wall defects in a rabbit model
    Gemma Pascual
    Department of Surgery and Medical Specialties Networking Research Center on Bioengineering, Biomaterials and Nanomedicine CIBER BBN Faculty of Medicine, Alcala University, Alcala de Henares, Madrid, Spain
    PLoS ONE 8:e80647. 2013
    ..This study assesses the behaviour of a new composite mesh by comparing it with two latest-generation composites currently used in clinical practice...
  42. doi request reprint Postimplantation host tissue response and biodegradation of biologic versus polymer meshes implanted in an intraperitoneal position
    G Pascual
    Department of Medical Specialties, Networking Research Center on Bioengineering, Biomaterials and Nanomedicine CIBER BBN, Faculty of Medicine, Alcala University, Alcala de Henares, Madrid, Spain
    Surg Endosc 28:559-69. 2014
    ..This study compared the in vitro and in vivo behaviors at the peritoneal interface of a new polymer material (Bio-A) and of two biologic non-cross-linked materials (Tutomesh [Tuto] and Strattice [St]), all biodegradable...
  43. doi request reprint Viability of engineered vessels as arterial substitutes
    Natalio Garcia-Honduvilla
    Department of Surgery, Faculty of Medicine, University of Alcala, Alcala de Henares, and Networking Research Center on Biomaterials and Nanomedicine CIBER BBN, Madrid, Spain
    Ann Vasc Surg 22:255-65. 2008
    ..In conclusion, engineered vessels showed improved initial patency over ePTFE grafts. The EC graft was best at combating restenosis, a good indicator of the long-term efficiency of the graft...
  44. ncbi request reprint [Role of surgery in metastases from breast cancer]
    Hipólito J Durán
    Departamento de Cirugia, Universidad de Alcala, Alcala de Henares, Madrid, Spain
    Cir Esp 82:3-10. 2007
    ....
  45. ncbi request reprint A biodegradable copolymer for the slow release of growth hormone expedites scarring in diabetic rats
    Francisco García-Esteo
    Department of Medical Specialities, Faculty of Medicine, University of Alcala, Madrid, Spain
    J Biomed Mater Res B Appl Biomater 81:291-304. 2007
    ..These effects give rise to a comparable wound healing process to that observed in healthy animals...