Varvara Trachana

Summary

Country: Spain

Publications

  1. pmc Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability
    Varvara Trachana
    Department of Immunology and Oncology, Centro Nacional de Biotecnología Consejo Superior de Investigaciones Científicas, Darwin 3, Campus de Cantoblanco, E 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 104:2691-6. 2007
  2. pmc Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle
    Astrid Alonso Guerrero
    Department of Immunology and Oncology, Centro Nacional de Biotecnología Consejo Superior de Investigaciones Científicas, Universidad Autonoma de Madrid, Cantoblanco Campus, 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 107:4159-64. 2010
  3. doi request reprint Synaptonemal complex assembly and H3K4Me3 demethylation determine DIDO3 localization in meiosis
    Ignacio Prieto
    Department of Immunology and Oncology, Centro Nacional de Biotecnologia CSIC, Darwin 3, 28049 Madrid, Spain
    Chromosoma 118:617-32. 2009

Collaborators

  • Anna Kouznetsova
  • Astrid Alonso Guerrero
  • Carlos Martinez-A
  • Cristina Pacios-Bras
  • Mercedes Cano Gamero
  • Karel H M van Wely
  • Agnes Fütterer
  • Ignacio Prieto
  • Juan Cruz Cigudosa
  • Nuria Panadero Díaz-Concha
  • Leonor Kremer
  • Herve Leh
  • Juan Pablo Albar
  • Esther Leonardo
  • Fernando Roncal
  • Antonio Serrano
  • Malcolm Buckle
  • Mónica Garcia-Gallo
  • Jose Luis Barbero

Detail Information

Publications3

  1. pmc Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability
    Varvara Trachana
    Department of Immunology and Oncology, Centro Nacional de Biotecnología Consejo Superior de Investigaciones Científicas, Darwin 3, Campus de Cantoblanco, E 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 104:2691-6. 2007
    ..Dido gene malfunction thus is reported to be part of an impaired signaling cascade that results in a defective mitotic checkpoint, leading to chromosome instability...
  2. pmc Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle
    Astrid Alonso Guerrero
    Department of Immunology and Oncology, Centro Nacional de Biotecnología Consejo Superior de Investigaciones Científicas, Universidad Autonoma de Madrid, Cantoblanco Campus, 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 107:4159-64. 2010
    ..Comparable defects were found in APC mutant cell lines, an independent system for spindle defects. On the basis of these results, we propose a model for break formation in which spindle defects lead to centromere shearing...
  3. doi request reprint Synaptonemal complex assembly and H3K4Me3 demethylation determine DIDO3 localization in meiosis
    Ignacio Prieto
    Department of Immunology and Oncology, Centro Nacional de Biotecnologia CSIC, Darwin 3, 28049 Madrid, Spain
    Chromosoma 118:617-32. 2009
    ..Our results indicate that histone H3 lysine 4 demethylation modulates DIDO3 localization in meiosis and suggest epigenetic regulation of the synaptonemal complex...