Varvara Trachana

Summary

Country: Spain

Publications

  1. ncbi Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability
    Varvara Trachana
    Department of Immunology and Oncology, Centro Nacional de Biotecnología Consejo Superior de Investigaciones Científicas, Darwin 3, Campus de Cantoblanco, E 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 104:2691-6. 2007
  2. ncbi Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle
    Astrid Alonso Guerrero
    Department of Immunology and Oncology, Centro Nacional de Biotecnología Consejo Superior de Investigaciones Científicas, Universidad Autonoma de Madrid, Cantoblanco Campus, 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 107:4159-64. 2010
  3. ncbi Synaptonemal complex assembly and H3K4Me3 demethylation determine DIDO3 localization in meiosis
    Ignacio Prieto
    Department of Immunology and Oncology, Centro Nacional de Biotecnologia CSIC, Darwin 3, 28049 Madrid, Spain
    Chromosoma 118:617-32. 2009

Collaborators

  • Anna Kouznetsova
  • Astrid Alonso Guerrero
  • Cristina Pacios-Bras
  • Agnes Fütterer
  • Mercedes Cano Gamero
  • Carlos Martinez-A
  • Karel H M van Wely
  • Ignacio Prieto
  • Juan Cruz Cigudosa
  • Nuria Panadero Díaz-Concha
  • Malcolm Buckle
  • Esther Leonardo
  • Leonor Kremer
  • Jose Luis Barbero
  • Fernando Roncal
  • Antonio Serrano
  • Juan Pablo Albar
  • Mónica Garcia-Gallo
  • Herve Leh

Detail Information

Publications3

  1. ncbi Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability
    Varvara Trachana
    Department of Immunology and Oncology, Centro Nacional de Biotecnología Consejo Superior de Investigaciones Científicas, Darwin 3, Campus de Cantoblanco, E 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 104:2691-6. 2007
    ..Dido gene malfunction thus is reported to be part of an impaired signaling cascade that results in a defective mitotic checkpoint, leading to chromosome instability...
  2. ncbi Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle
    Astrid Alonso Guerrero
    Department of Immunology and Oncology, Centro Nacional de Biotecnología Consejo Superior de Investigaciones Científicas, Universidad Autonoma de Madrid, Cantoblanco Campus, 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 107:4159-64. 2010
    ..Comparable defects were found in APC mutant cell lines, an independent system for spindle defects. On the basis of these results, we propose a model for break formation in which spindle defects lead to centromere shearing...
  3. ncbi Synaptonemal complex assembly and H3K4Me3 demethylation determine DIDO3 localization in meiosis
    Ignacio Prieto
    Department of Immunology and Oncology, Centro Nacional de Biotecnologia CSIC, Darwin 3, 28049 Madrid, Spain
    Chromosoma 118:617-32. 2009
    ..Our results indicate that histone H3 lysine 4 demethylation modulates DIDO3 localization in meiosis and suggest epigenetic regulation of the synaptonemal complex...