Antonio Torrelo

..This unusual association may be considered a further example of didymosis, for which we propose the term, didymosis aplasticopsilolipara...

..No side effects of Advantan were reported. In an infant with newly diagnosed eczema, Advantan was safe and effective in alleviating lesions and scratching severity and restoring sleep...

..No side effects of Advantan were reported; the patient's parents expressed a high level of satisfaction with treatment. Advantan was safe and effective in controlling a severe pruritic flare of chronic AD in a small child...

..These results highlight that although reported compliance was high, there were still non-compliance attitudes and concerns about treatments that should be answered. Finally, a significant impact on patients' life was confirmed...

..Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by tumors and hamartomas in several organs including the skin...

..More recently, the term phacomatosis cesiomarmorata (cesius = blue) has been proposed. We believe phacomatosis cesiomarmorata is another example of twin spotting or didymosis...

..Pyoderma gangrenosum in infants has a good response to therapy, and healing is usually achieved...

..Histology studies show an increase of collagen fibers in the dermis and a variable decrease in elastic fibers. We discuss the case of a child with a solitary giant cerebriform collagenoma on the lumbar region of her back...

..This article reviews in detail the specific types of panniculitis of the newborn and discusses the pediatric aspects of the panniculitis that is often seen in adults...

..Trauma has been implicated as an important trigger of morphea, both in children and in adults. Furthermore, vaccines might induce an immune response, which could lead to morphea in predisposed individuals...

..This entails some added concerns. In this article, we review the most relevant findings that have arisen in the last five years in regards to the treatment of AD with tacrolimus in children...

..Both patients had congenital immunodeficiency. This skin condition of the newborn, with distinct clinical and histopathologic features, is a manifestation of immunodeficiency that has not been previously described...

..We propose the acronym CANDLE (chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature) syndrome for this newly described disorder, which is probably genetic in origin...

..Our work gives more consistency to the idea that nevi reflect mosaicism, because they display repetitive shapes and patterns...

..Several types of epidermal keratinocytic nevus are recognized...

..To our knowledge, widespread comedonal and cystic acne have not been previously reported in Patau syndrome...

..PALP might be considered a localized or regional form of LP or a distinct lymphoproliferative disorder; in any case, at least a cautious long-term follow up is recommended, with attention to the possible development of true lymphoma...

..No systemic lesions of juvenile xanthogranuloma were identified. Lichenoid juvenile xanthogranuloma is a very infrequent variant of juvenile xanthogranuloma...

..It is an acquired dermatosis that occurs most frequently in Central and South America. EDP usually appears in adults, but some isolated cases and small series have been reported in prepubertal children...

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..We report a case of systemic juvenile xanthogranuloma in a female newborn with mainly skin, bone marrow, and liver involvement, leading to death at the age of 2 months...

..We report on two unrelated patients who presented with typical clinical and histologic features of HMD along with other unreported clinical findings...

..PPK shows an elevated incidence of development of malignant lesions both on the sebaceous or epidermal nevus component as well as on the nevus spilus one...

..Prospective studies are needed to establish the exact role of propranolol in the treatment of infantile hemangiomas...

..Histopathologic study of lesions of cutaneous mucormycosis usually shows suppurative granulomas involving the deep dermis and subcutaneous fat. Large, broad and non-septate fungal hyphae are easily identified within the necrotic areas...

..We report a 5-year-old girl with malignant atrophic papulosis who presented with widespread skin lesions from early infancy and severe visual and neurological impairment...

..We hypothesize that this uncommon co-occurrence may represent a further example of twin spotting and may be categorized as a new, distinct type of phacomatosis...

..Mediastinal involvement is rare in hemangioma and paravertebral and intraspinal extension of hemangioma have seldom reported and may have been overlooked in the past...

..We describe emperipolesis in the cutaneous lesions of a patient with H syndrome, further supporting the relationship between Rosai-Dorfman disease and H syndrome...

..Cutaneous anaplastic large cell lymphoma, though rare in children, may occur, and should be considered when a rapidly growing ulcerating skin lesion appears...

..An association with some autoimmune manifestations is highlighted...

..Eosinophilic pustular folliculitis (EPF) of infancy is characterized by the presence of pustular lesions containing eosinophils. It is the least well-characterized of the EPF diseases...

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..The vascular endothelial growth factor receptor might be involved, as well as incomplete apoptosis during treatment...

..We present a case of multiple cellular neurothekeomas arising on a café-au-lait macule in a child, a situation that has not been reported to our knowledge...

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..In addition, it appears that a number of melanomas develop on the site of partially or completely excised lesions, or even away from the CMN itself, making the appropriateness of prophylactic surgery increasingly doubtful...

..The etiology is uncertain, and several teratogenic agents such as methimazole have been involved. We report two cases of ACC and other anomalies in newborns exposed to methimazole during pregnancy...

..Punch biopsy and clinical follow up could be an alternative approach to the surgical excision in some cases of dermatomyofibroma, particularly in instances in which surgery might inflict cosmetic defects...

..She had no extracutaneous anomalies. We hypothesize that this unusual coexistence of skin lesions may represent a further example of "twin spotting"...

..A child developed multiple Beau's lines and periungueal pyogenic granulomas after admission to the intensive care unit. Immobilization, hypoxia, and drugs might have acted as potential causative factors...

..We emphasize the persistence of skin lesions in the absence of bone marrow infiltration by leukemia throughout the course of the disease...

..To our knowledge, this is the first case reported in the literature...

..To our knowledge, only one previous biopsy-proven case of erythema multiforme during the neonatal period has been reported...

..We report on an infant that presented with congenital plate-like osteoma cutis, showing the earliest clinical aspect of the lesion and its initial morphologic changes...

..Schamberg's purpura (progressive pigmentary dermatosis or pigmented purpuric dermatosis) is uncommonly described in preadolescent children...

..The case of a 7-year-old girl with a prominent invasive lymphatic malformation on the lumbosacral area and massive osteolysis of the pelvic girdle is reported...

..Epidermal keratinization disorders comprise a heterogeneous group of skin diseases that share the common feature of abnormal epidermal maturation, often leading to a disturbed stratum corneum...

..We present the case of a 12-year-old girl with the triad of ichthyosis linearis circumflexa, trichorrhexis invaginata and atopic dermatitis, characteristic of Netherton syndrome...

..We present the case of an Ecuadorian boy whose visit was motivated by lesions in the oral mucosa consistent with a diagnosis of FEH, which were confirmed in the histological study, and in which HPV type 13 DNA was identified...

..We ignore the frequency of systemic involvement in childhood mastocytosis, its outcome, and which are the main clinical and laboratory parameters associated with persistence into adult mastocytosis and its severity...

..This case emphasizes the spectrum of different phenotypical manifestations of mutations in the p63 gene and underlines the possible role of this gene as a tumor suppressor...

..Capillary malformations are a novel finding for children with Dyke-Davidoff-Masson syndrome...

..In this paper we report the experience with 6 children having symptomatic airway hemangiomas treated with propranolol. All children improved their respiratory symptoms dramatically and did not need additional interventions...

..We review the published cases and propose the term 'sclerotic hypopigmented GCMN as a common descriptor of this type of congenital melanocytic naevus...

..We found only one previous similar case in a textbook, and we support the classification of this condition as phacomatosis pigmentovascularis type V...

..We review previous reports of this entity with clinical pictures and note that in most instances, the defects are of the nonmembranous variant...