Jordi Surralles

Summary

Country: Spain

Publications

  1. pmc Dysfunctional telomeres in primary cells from Fanconi anemia FANCD2 patients
    Ivana Joksic
    Vinca Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia
    Genome Integr 3:6. 2012
  2. pmc Clusters of transcription-coupled repair in the human genome
    Jordi Surralles
    Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Proc Natl Acad Sci U S A 99:10571-4. 2002
  3. pmc Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner
    Alex Lyakhovich
    Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, Edifici C, Bellaterra, Barcelona 08193, Spain
    Genome Integr 2:4. 2011
  4. pmc Molecular cross-talk among chromosome fragility syndromes
    Jordi Surralles
    Group of Mutagenesis, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Genes Dev 18:1359-70. 2004
  5. ncbi Breaks at telomeres and TRF2-independent end fusions in Fanconi anemia
    Elsa Callen
    Group of Mutagenesis, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Hum Mol Genet 11:439-44. 2002
  6. pmc Mutations in ERCC4, Encoding the DNA-Repair Endonuclease XPF, Cause Fanconi Anemia
    Massimo Bogliolo
    Genome Instability and DNA Repair Group, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, Bellaterra, 08193 Barcelona, Spain Centre for Biomedical Network Research on Rare Diseases, Instituto de Salud Carlos III, Bellaterra, 08193 Barcelona, Spain
    Am J Hum Genet 92:800-6. 2013
  7. ncbi A common founder mutation in FANCA underlies the world's highest prevalence of Fanconi anemia in Gypsy families from Spain
    Elsa Callen
    Universitat Autònoma de Barcelona and the Hospital Meterno Infantil Vall d Hebron, Barcelona, Spain
    Blood 105:1946-9. 2005
  8. doi On the role of FAN1 in Fanconi anemia
    Juan P Trujillo
    Genome Instability and DNA Repair Group, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    Blood 120:86-9. 2012
  9. ncbi Telomere dysfunction in genome instability syndromes
    Elsa Callen
    Group of Mutagenesis, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain
    Mutat Res 567:85-104. 2004
  10. ncbi Relationship between chromosome fragility, aneuploidy and severity of the haematological disease in Fanconi anaemia
    Elsa Callen
    Group of Mutagenesis, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Mutat Res 504:75-83. 2002

Collaborators

Detail Information

Publications22

  1. pmc Dysfunctional telomeres in primary cells from Fanconi anemia FANCD2 patients
    Ivana Joksic
    Vinca Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia
    Genome Integr 3:6. 2012
    ..abstract:..
  2. pmc Clusters of transcription-coupled repair in the human genome
    Jordi Surralles
    Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Proc Natl Acad Sci U S A 99:10571-4. 2002
    ....
  3. pmc Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner
    Alex Lyakhovich
    Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, Edifici C, Bellaterra, Barcelona 08193, Spain
    Genome Integr 2:4. 2011
    ..abstract:..
  4. pmc Molecular cross-talk among chromosome fragility syndromes
    Jordi Surralles
    Group of Mutagenesis, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Genes Dev 18:1359-70. 2004
  5. ncbi Breaks at telomeres and TRF2-independent end fusions in Fanconi anemia
    Elsa Callen
    Group of Mutagenesis, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Hum Mol Genet 11:439-44. 2002
    ....
  6. pmc Mutations in ERCC4, Encoding the DNA-Repair Endonuclease XPF, Cause Fanconi Anemia
    Massimo Bogliolo
    Genome Instability and DNA Repair Group, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, Bellaterra, 08193 Barcelona, Spain Centre for Biomedical Network Research on Rare Diseases, Instituto de Salud Carlos III, Bellaterra, 08193 Barcelona, Spain
    Am J Hum Genet 92:800-6. 2013
    ....
  7. ncbi A common founder mutation in FANCA underlies the world's highest prevalence of Fanconi anemia in Gypsy families from Spain
    Elsa Callen
    Universitat Autònoma de Barcelona and the Hospital Meterno Infantil Vall d Hebron, Barcelona, Spain
    Blood 105:1946-9. 2005
    ..The high carrier frequency makes the Spanish Gypsies a population model to study FA heterozygote mutations in cancer...
  8. doi On the role of FAN1 in Fanconi anemia
    Juan P Trujillo
    Genome Instability and DNA Repair Group, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    Blood 120:86-9. 2012
    ..Clinically, there were no symptoms pointing the way to FA. Our results suggest that FAN1 has a minor role in interstrand crosslink repair compared with true FA genes and exclude FAN1 as a novel FA gene...
  9. ncbi Telomere dysfunction in genome instability syndromes
    Elsa Callen
    Group of Mutagenesis, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain
    Mutat Res 567:85-104. 2004
    ..Therefore, it is essential to understand the interplay between telomere biology and genome stability. This review is focused in the dual role of chromosome fragility proteins in telomere maintenance...
  10. ncbi Relationship between chromosome fragility, aneuploidy and severity of the haematological disease in Fanconi anaemia
    Elsa Callen
    Group of Mutagenesis, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Mutat Res 504:75-83. 2002
    ..None of the variables included in the present investigation (chromosome fragility, chromosome numerical abnormalities and haematological status) were correlated to telomere length...
  11. doi Coordinated action of the Fanconi anemia and ataxia telangiectasia pathways in response to oxidative damage
    Pau Castillo
    Genome Instability and DNA Repair Group, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, Spain
    DNA Repair (Amst) 10:518-25. 2011
    ..We conclude that the handling of DNA damage after H(2)O(2)-induced oxidative stress requires the coordinated action of FANCD2 and ATM...
  12. pmc Origin, functional role, and clinical impact of Fanconi anemia FANCA mutations
    Maria Castella
    Genome Instability and DNA Repair Group, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, Campus de Bellaterra s n, Barcelona, Spain
    Blood 117:3759-69. 2011
    ..This may explain the observed lack of correlation between type of FANCA mutation and cellular phenotype or clinical severity in terms of age of onset of hematologic disease or number of malformations...
  13. doi Chromosome fragility in patients with Fanconi anaemia: diagnostic implications and clinical impact
    Maria Castella
    Genome Instability and DNA Repair Group, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, and Pediatric Haemato Oncology Service, Hospital Materno Infantil Vall d Hebron, Barcelona, Spain
    J Med Genet 48:242-50. 2011
    ..Chromosome fragility induced by DNA interstrand crosslink (ICL)-inducing agents such as diepoxybutane (DEB) or mitomycin C (MMC) is the 'gold standard' test for the diagnosis of FA...
  14. ncbi FANCD2 depletion sensitizes cancer cells repopulation ability in vitro
    Alex Lyakhovich
    Group of Mutagenesis, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Cancer Lett 256:186-95. 2007
    ..In summary, the results we presented show proof of principle that opens new possibilities for further preclinical trials...
  15. pmc Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability
    Massimo Bogliolo
    Group of Mutagenesis, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    EMBO J 26:1340-51. 2007
    ..Consequently, histone H2AX is functionally connected to the FA/BRCA pathway to resolve stalled replication forks and prevent chromosome instability...
  16. ncbi A DIGE-based approach to study interacting proteins
    Alex Lyakhovich
    Group of Mutagenesis, Department of Genetics and Microbiology, Universitat, Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    J Biochem Biophys Methods 70:693-5. 2007
    ..Thus, we believe this study shows a good potential for investigating various interacting partners and benefits towards creation of interactome...
  17. pmc Mutagenic stress modulates the dynamics of CTG repeat instability associated with myotonic dystrophy type 1
    Elisabeth Piñeiro
    Grup de Mutagenesi, Unitat de Genètica, Departament de Genetica i de Microbiologia, Edifici Cn, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Nucleic Acids Res 31:6733-40. 2003
    ....
  18. doi Constitutive activation of caspase-3 and Poly ADP ribose polymerase cleavage in fanconi anemia cells
    Alex Lyakhovich
    Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Mol Cancer Res 8:46-56. 2010
    ..Thus, the current study is the first evidence demonstrating the damage-independent activation of caspase-3 and PARP in FA cells, which seems to occur through mitogen-activated protein kinase activation and TNF-alpha oversecretion...
  19. ncbi New roads to FA/BRCA pathway: H2AX
    Alex Lyakhovich
    Group of Mutagenesis, Department of Genetics and Microbiology, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    Cell Cycle 6:1019-23. 2007
    ..Here, we discuss a model for the FA pathway and how it could partially explain the common phenotypes of H2AX, BRCA2 and FA deficiencies...
  20. doi Quick two-dimensional differential in gel electrophoresis-based method to determine length and secondary structures of telomeric DNA
    Alex Lyakhovich
    Department of Genetics and Microbiology, Universitad Autonoma de Barcelona, Edifici C UAB Campus, Bellaterra 08193, Spain
    Anal Biochem 384:356-8. 2009
    ..It can be applied to any area requiring quick and evident measurement of structural DNA changes...
  21. ncbi Role of the Met(287)Thr polymorphism in the AS3MT gene on the metabolic arsenic profile
    Alba Hernandez
    Grup de Mutagenesi, Departament de Genetica i de Microbiologia, Universitat Autonoma de Barcelona, Bellaterra, Spain
    Mutat Res 637:80-92. 2008
    ....
  22. ncbi Glutathione S-transferase polymorphisms in thyroid cancer patients
    Alba Hernandez
    Grup de Mutagenesi, Departament de Genetica i de Microbiologia, Universitat Autonoma de Barcelona, Bellaterra, Spain
    Cancer Lett 190:37-44. 2003
    ..In conclusion, the results obtained in this study clearly suggest that those susceptibility factors related to the different GST polymorphic enzymes are not a predisposing factor in thyroid cancer disease...