Manuel Sosa

Summary

Country: Spain

Publications

  1. doi Trends in the incidence of hip fracture in Gran Canaria, Canary Islands, Spain: 2007-2011 versus 1989-1993
    M Sosa
    Investigation Group on Osteoporosis and Bone Mineral Diseases, University of Las Palmas de Gran Canaria, Espronceda 2, 35005, Las Palmas de Gran Canaria, Canary Islands, Spain
    Osteoporos Int 26:1361-6. 2015
  2. doi Beta-blocker use is associated with fragility fractures in postmenopausal women with coronary heart disease
    Manuel Sosa
    University of Las Palmas de Gran Canaria, Investigation Group on Osteoporosis, Hospital University Insular, Spanish Society of Bone Investigation and Mineral Metabolism SEIOMM, Working Group on Ultrasound and Bone Mineral Metabolism GIUMO, Espronceda 2, 35005 Las Palmas de Gran Canaria, Canary Island, Spain
    Aging Clin Exp Res 23:112-7. 2011
  3. ncbi [Evidenced based medicine and drugs approved for the treatment of osteoporosis. Role of calcium and vitamin D]
    M Sosa Henriquez
    Universidad de Las Palmas de Gran Canaria, Grupo de Investigación sobre Osteoporosis y Metabolismo Mineral, Hospital Universitario Insular, Unidad metabólica ósea, Las Palmas, Gran Canaria, Espana
    Rev Clin Esp 209:25-36. 2009
  4. ncbi Bone mineral density and risk of fractures in aging, obese post-menopausal women with type 2 diabetes. The GIUMO Study
    Manuel Sosa
    University of Las Palmas de Gran Canaria, Investigation Group on Osteoporosis, Hospital University Insular, Bone Metabolic Unit, Las Palmas de Gran Canaria, Canary Islands, Spain
    Aging Clin Exp Res 21:27-32. 2009
  5. doi Poverty is a risk factor for osteoporotic fractures
    M C Navarro
    Health Education and Promotion Working Group, Canary Islands, Spain
    Osteoporos Int 20:393-8. 2009
  6. doi Postmenopausal Canarian women receiving oral glucocorticoids have an increased prevalence of vertebral fractures and low values of bone mineral density measured by quantitative computer tomography and dual X-ray absorptiometry, without significant changes
    M Sosa
    University Hospital Insular, Department of Internal Medicine, Bone Metabolic Unit, University of Las Palmas de Gran Canaria, Investigation Group on Osteoporosis, Canary Islands, Spain
    Eur J Intern Med 19:51-6. 2008
  7. ncbi [Parathyroid hormone in the treatment of osteoporosis]
    M Sosa Henriquez
    Universidad de Las Palmas de Gran Canaria, Grupo de Investigación en Osteoporosis
    An Med Interna 24:87-97. 2007
  8. doi Discriminative ability of heel quantitative ultrasound in postmenopausal women with prevalent vertebral fractures: application of optimal threshold cutoff values using classification and regression tree models
    María del Carmen Navarro
    Group of Investigation on Education and Promotion of Health, University of Las Palmas de Gran Canaria, Las Palmas, Canary Islands, Spain
    Calcif Tissue Int 91:114-20. 2012
  9. ncbi Collagen type 1 (COL1A1) Sp1 binding site polymorphism is associated with osteoporotic fractures but not with bone density in post-menopausal women from the Canary Islands: a preliminary study
    Mary C Navarro
    University of Las Palmas de Gran Canaria, Osteoporosis Research Group, Bone Metabolic Unit, Hospital University Insular, Gran Canaria, Canary Islands, Spain
    Aging Clin Exp Res 19:4-9. 2007
  10. doi Anthropometric and gynaecological history according to the socioeconomic status of postmenopausal women: poverty and the menopause
    Manuel Carmen Navarro
    Health Education and Promotion Working Group, Insular University Hospital, Las Palmas de Gran Canaria, Canary Islands, Spain
    Menopause Int 16:12-7. 2010

Collaborators

Detail Information

Publications21

  1. doi Trends in the incidence of hip fracture in Gran Canaria, Canary Islands, Spain: 2007-2011 versus 1989-1993
    M Sosa
    Investigation Group on Osteoporosis and Bone Mineral Diseases, University of Las Palmas de Gran Canaria, Espronceda 2, 35005, Las Palmas de Gran Canaria, Canary Islands, Spain
    Osteoporos Int 26:1361-6. 2015
    ..The incidence in 2007-2011 was 24 % higher than in 1989, but did not differ between 2007-2011 and 1993. These findings suggest a trend to stabilize the incidence of hip fracture...
  2. doi Beta-blocker use is associated with fragility fractures in postmenopausal women with coronary heart disease
    Manuel Sosa
    University of Las Palmas de Gran Canaria, Investigation Group on Osteoporosis, Hospital University Insular, Spanish Society of Bone Investigation and Mineral Metabolism SEIOMM, Working Group on Ultrasound and Bone Mineral Metabolism GIUMO, Espronceda 2, 35005 Las Palmas de Gran Canaria, Canary Island, Spain
    Aging Clin Exp Res 23:112-7. 2011
    ..2) To study the possible influence of a number of drugs, statins, thiazides and beta-blockers, on BMD and fractures...
  3. ncbi [Evidenced based medicine and drugs approved for the treatment of osteoporosis. Role of calcium and vitamin D]
    M Sosa Henriquez
    Universidad de Las Palmas de Gran Canaria, Grupo de Investigación sobre Osteoporosis y Metabolismo Mineral, Hospital Universitario Insular, Unidad metabólica ósea, Las Palmas, Gran Canaria, Espana
    Rev Clin Esp 209:25-36. 2009
    ..So, the correct prescription of a treatment for osteoporosis should include general measurements, the chosen drug and a supplement of calcium and Vitamin D...
  4. ncbi Bone mineral density and risk of fractures in aging, obese post-menopausal women with type 2 diabetes. The GIUMO Study
    Manuel Sosa
    University of Las Palmas de Gran Canaria, Investigation Group on Osteoporosis, Hospital University Insular, Bone Metabolic Unit, Las Palmas de Gran Canaria, Canary Islands, Spain
    Aging Clin Exp Res 21:27-32. 2009
    ..Type 2 diabetes mellitus (DM) has a high prevalence in aging obese postmenopausal women. It is not clear whether or not diabetes produces an increase in bone mineral density or an increase in fracture rates...
  5. doi Poverty is a risk factor for osteoporotic fractures
    M C Navarro
    Health Education and Promotion Working Group, Canary Islands, Spain
    Osteoporos Int 20:393-8. 2009
    ..We found that postmenopausal women with low socioeconomic status had lower values of BMD at the lumbar spine, a higher prevalence of densitometric osteoporosis, and a higher prevalence of total and vertebral fractures...
  6. doi Postmenopausal Canarian women receiving oral glucocorticoids have an increased prevalence of vertebral fractures and low values of bone mineral density measured by quantitative computer tomography and dual X-ray absorptiometry, without significant changes
    M Sosa
    University Hospital Insular, Department of Internal Medicine, Bone Metabolic Unit, University of Las Palmas de Gran Canaria, Investigation Group on Osteoporosis, Canary Islands, Spain
    Eur J Intern Med 19:51-6. 2008
    ..Moreover, in this setting, the importance of secondary hyperparathyroidism is still controversial...
  7. ncbi [Parathyroid hormone in the treatment of osteoporosis]
    M Sosa Henriquez
    Universidad de Las Palmas de Gran Canaria, Grupo de Investigación en Osteoporosis
    An Med Interna 24:87-97. 2007
    ..5) an a high risk for fracture. Other potential uses are glucocorticoid-induced and other secondary osteoporosis. The use of PTH is not recommended for more than 18 months for teriparatida and 24 months for PTH 1-84...
  8. doi Discriminative ability of heel quantitative ultrasound in postmenopausal women with prevalent vertebral fractures: application of optimal threshold cutoff values using classification and regression tree models
    María del Carmen Navarro
    Group of Investigation on Education and Promotion of Health, University of Las Palmas de Gran Canaria, Las Palmas, Canary Islands, Spain
    Calcif Tissue Int 91:114-20. 2012
    ..The application of decision trees (CART analyses) was helpful to define the optimal threshold QUS values...
  9. ncbi Collagen type 1 (COL1A1) Sp1 binding site polymorphism is associated with osteoporotic fractures but not with bone density in post-menopausal women from the Canary Islands: a preliminary study
    Mary C Navarro
    University of Las Palmas de Gran Canaria, Osteoporosis Research Group, Bone Metabolic Unit, Hospital University Insular, Gran Canaria, Canary Islands, Spain
    Aging Clin Exp Res 19:4-9. 2007
    ..The aim of this preliminary work was to ascertain whether this association is present in women from the Canary Islands...
  10. doi Anthropometric and gynaecological history according to the socioeconomic status of postmenopausal women: poverty and the menopause
    Manuel Carmen Navarro
    Health Education and Promotion Working Group, Insular University Hospital, Las Palmas de Gran Canaria, Canary Islands, Spain
    Menopause Int 16:12-7. 2010
    ..In this work we study the possible association between poverty and the prevalence of obesity and oophorectomy in a population of postmenopausal women...
  11. doi Osteoporosis and metabolic syndrome according to socio-economic status, contribution of PTH, vitamin D and body weight: The Canarian Osteoporosis Poverty Study (COPS)
    María del Carmen Navarro
    Research Group on Education and Promotion of Health, University of Las Palmas de Gran Canaria, Canary Islands, Spain
    Clin Endocrinol (Oxf) 78:681-6. 2013
    ....
  12. doi Risk factors for prediction of inadequate response to antiresorptives
    Adolfo Diez-Perez
    Hospital del Mar IMIM UAB, Department of Internal Medicine, Barcelona, Spain
    J Bone Miner Res 27:817-24. 2012
    ..More potent regimes should be developed and adequate supplementation implemented to solve this problem...
  13. doi [Morbidity in postmenopausal women with poverty]
    Mary Carmen Navarro
    Universidad de Las Palmas de Gran Canaria, Gran Canaria
    Rev Med Chil 138:188-95. 2010
    ..Less favored social classes usually have more unhealthy life-styles and a more difficult access to Health Resources...
  14. ncbi Postmenopausal women with colles' fracture have lower values of bone mineral density than controls as measured by quantitative ultrasound and densitometry
    Manuel Sosa
    University of Las Palmas de Gran Canaria, Hospital University Insular, Bone Metabolic Unit, Las Palmas de Gran Canaria, Canary Islands, Spain
    J Clin Densitom 8:430-5. 2005
    ..However, the ability of these techniques to discriminate is low because the values for the area under ROC curve are 0.60 for L2-L4 and 0.63 for a formula derived of the combination of L2-L4 and height...
  15. doi Discriminative ability of heel quantitative ultrasound in postmenopausal women with prevalent low-trauma fractures: application of optimal threshold cutoff values using CART models
    María del Carmen Navarro
    Group of Investigation on Education and Promotion of Health, Department of Nursery, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Canary Islands, Spain
    J Clin Densitom 14:492-8. 2011
    ..The application of decision trees (CART analyses) was helpful to define the optimal threshold QUS values...
  16. ncbi Bone mass, bone turnover, vitamin D, and estrogen receptor gene polymorphisms in male to female transsexuals: effects of estrogenic treatment on bone metabolism of the male
    Manuel Sosa
    Department of Clinical and Surgical Sciences, Centre of Health Sciences, University of Las Palmas de Gran Canaria, Las Palmas, Spain
    J Clin Densitom 6:297-304. 2003
    ..We found no association between the transsexual phenotype and the distribution of vitamin D receptor (BsmI) and estrogen receptor (ER-Pvu and ER-Xba)...
  17. ncbi [Influence of the different bisphosphonates dose regimens on its tolerability]
    M Sosa Henriquez
    Universidad de Las Palmas de Gran Canaria, Facultad de Ciencias de la Salud, Grupo de Trabajo en Osteoporosis y Metabolismo Mineral, Hospital Universitario Insular, Las Palmas de Gran Canaria
    An Med Interna 23:596-601. 2006
    ..The introduction of new bisphosphonates that can be taken weekly or even better monthly, has improved notably the adherence and compliance to osteoporosis treatment...
  18. ncbi Quantitative ultrasound calcaneus measurements: normative data and precision in the spanish population
    M Sosa
    University of Las Palmas de Gran Canaria Health Sciences Center and Department of Clinical Sciences, Hospital University Insular, Bone Metabolic Unit, Canary Islands, Spain
    Osteoporos Int 13:487-92. 2002
    ..40% for SOS and 2.67% for BUA. Our results are comparable to reference population data previously published in other countries and may serve as reference normative data for both genders in Spain...
  19. ncbi Inhaled steroids do not decrease bone mineral density but increase risk of fractures: data from the GIUMO Study Group
    M Sosa
    University of Las Palmas de Gran Canria, Hospital University Insular, Bone Metabolic Unit, Apartado 550, 35080 Las Palmas de Gran Canaria, Canary Islands, Spain
    J Clin Densitom 9:154-8. 2006
    ..79 (95% CI: 1.19-6.54). Inhaled steroids do not appear to decrease BMD, but are associated with an increased risk of fracture in women...
  20. ncbi Effect of two forms of alendronate administration upon bone mass after two years of treatment
    M Sosa
    Department of Medical and Surgical Sciences, University of Las Palmas de Gran Canaria, Hospital University Insular, Service of Internal Medicine, Bone Metabolic Unit, Las Palmas de Gran Canaria, Canary Islands, Spain
    J Clin Densitom 5:27-34. 2002
    ..The alternative administration of 10 mg alendronate at noon had the same effect on bone mineral metabolism than its traditional administration in the morning, but the rate of withdrawals was significantly lower...
  21. ncbi [Clinical trials: placebo in the treatment of osteoporosis and in the prevention of vertebral fractures]
    M J Gómez de Tejada
    Med Clin (Barc) 118:119. 2002