Eduardo Sobarzo Sanchez
Affiliation: Santiago de Compostela
Hajialyani M, Hosein Farzaei M, Echeverría J, Nabavi S, Uriarte E, Sobarzo Sanchez E. Hesperidin as a Neuroprotective Agent: A Review of Animal and Clinical Evidence. Molecules. 2019;24: pubmed publisher
..Further clinical trials are also required for confirming neuroprotective efficacy of this natural flavonoid and evaluating its safety profile. ..
Dhiman P, Malik N, Sobarzo Sanchez E, Uriarte E, Khatkar A. Quercetin and Related Chromenone Derivatives as Monoamine Oxidase Inhibitors: Targeting Neurological and Mental Disorders. Molecules. 2019;24: pubmed publisher
..The current review made an attempt to summarizing and critically evaluating the new findings on the quercetin and related flavonoid derivatives functions as potent MAO isoform inhibitors. ..
Amin S, Ullah B, Ali M, Rauf A, Khan H, Uriarte E, et al
. Potent in Vitro α-Glucosidase Inhibition of Secondary Metabolites Derived from Dryopteris cycadina. Molecules. 2019;24: pubmed publisher
..In short, the secondary metabolites isolated from D. cycadina demonstrated potent α-glucosidase inhibition that were supported by molecular docking with a high docking score. ..
Nabavi S, Sobarzo Sanchez E, Nabavi S, Daglia M, Moghaddam A, Silva A. Behavioral effects of 2,3-dihydro- and oxoisoaporphine derivatives in post stroke-depressive like behavior in male BALB/c mice. Curr Top Med Chem. 2013;13:2127-33 pubmed
..We concluded that these alkaloids showed antidepressant actions and therefore can be used for treatment of post strokedepressive like behavior in acute ischemic stroke patients. ..
López M, Fontenla J, Uriarte E, Santana L, Sobarzo Sanchez E. Comparison of the antidepressive effects of trans-resveratrol and 5-methoxy-7H-dibenzo[de,h]quinolin-7-one. Curr Top Med Chem. 2014;14:234-8 pubmed
..The pharmaceutical use of OXO 4 in the treatment of depressive disorders is a therapeutic alternative to be studied. ..
Moghaddam A, Sobarzo Sanchez E, Nabavi S, Daglia M, Nabavi S. Evaluation of the antipsychotic effects of 2-(dimethylamino)- and 2-(methylamino)-7H-naphtho[1,2,3-de]quinolin-7-one derivatives in experimental model of psychosis in mice. Curr Top Med Chem. 2014;14:229-33 pubmed
..Overall, these results showed that these alkaloids have anti-schizophrenia efficacy and due to their low side effects, they can be used as a new strategy for the treatment of depressive symptoms of schizophrenia patients. ..
Sobarzo Sanchez E, Nabavi S, Uriarte E, Santana L. Nanoparticles in the treatment of mental disorders: a new tool in the psychiatric medication. Curr Top Med Chem. 2015;15:282-6 pubmed
..Thus, this review shows the formation of nanoparticles for a direct application of the psychiatric medication, may be considered as a new pharmacological tool by its low cytotoxicity and high efficiency. ..
Sobarzo Sanchez E, Soto P, Valdés Rivera C, Sánchez G, Hidalgo M. Applied biological and physicochemical activity of isoquinoline alkaloids: oxoisoaporphine and boldine. Molecules. 2012;17:10958-70 pubmed publisher
..No hemolysis was detected for boldine hydrochloride and its salts without irradiation. In solutions irradiated before incubation (at concentrations over 200 ppm) photoproducts were toxic to the nauplii of Artemia salina. ..
Nabavi S, Habtemariam S, Ahmed T, Sureda A, Daglia M, Sobarzo Sanchez E, et al
. Polyphenolic Composition of Crataegus monogyna Jacq.: From Chemistry to Medical Applications. Nutrients. 2015;7:7708-28 pubmed publisher
..Therefore, the aim of this paper is to provide a critical review of the available scientific literature about pharmacological activities as well as botanical aspects, phytochemistry and clinical impacts of C. monogyna. ..