J Castillo

Summary

Affiliation: Santiago de Compostela
Country: Spain

Publications

  1. ncbi [Guidelines for action and diagnosis in atherothrombosis in Spain: ADA Study (Action and Diagnosis in Atherothrombosis)]
    J Castillo
    Servicio de Neurología Hospital Clínico Universitario Santiago de Compostela La Coruna Spain
    Rev Clin Esp 202:202-8. 2002
  2. ncbi Predictors of deteriorating cerebral infarct: role of inflammatory mechanisms. Would its early treatment be useful?
    J Castillo
    Department of Neurology, Hospital Clinico Universitario, University of Santiago de Compostela, Spain
    Cerebrovasc Dis 11:40-8. 2001
  3. ncbi [Physiopathology of cerebral ischemia]
    J Castillo
    Servicio de Neurologia, Hospital Xeral de Galicia, Universidad de Santiago de Compostela, Espana
    Rev Neurol 30:459-64. 2000
  4. ncbi Molecular signatures of brain injury after intracerebral hemorrhage
    J Castillo
    Department of Neurology, Hospital Clinico Universitario, Santiago de Compostela, Spain
    Neurology 58:624-9. 2002
  5. ncbi Neuroprotective effects of aspirin in patients with acute cerebral infarction
    Jose Castillo
    Department of Neurology, Hospital Clinico Universitario de Santiago de Compostela, c Travesía da Choupana, s n 15706, Santiago de Compostela, Spain
    Neurosci Lett 339:248-50. 2003
  6. ncbi [Consensus review. Pharmacological neuroprotection in cerebral ischemia: is it still a therapeutic option?]
    J Castillo
    Hospital Clinico Universitario, Santiago de Compostela
    Neurologia 18:368-84. 2003
  7. ncbi The release of tumor necrosis factor-alpha is associated with ischemic tolerance in human stroke
    Jose Castillo
    Department of Neurology, Hospital Clinico Universitario, University of Santiago de Compostela, Travesa da Choupana s n, 15706 Santiago de Compostela, Spain
    Ann Neurol 54:811-9. 2003
  8. ncbi Biochemical changes and inflammatory response as markers for brain ischaemia: molecular markers of diagnostic utility and prognosis in human clinical practice
    Jose Castillo
    Department of Neurology, Hospital Clinico Universitario, Universidad de Santiago de Compostela, Santiago de Compostela, Spain
    Cerebrovasc Dis 17:7-18. 2004
  9. ncbi Blood pressure decrease during the acute phase of ischemic stroke is associated with brain injury and poor stroke outcome
    Jose Castillo
    Department of Neurology, Hospital Clinico Universitario, University of Santiago de Compostela, Spain
    Stroke 35:520-6. 2004
  10. ncbi [Metalloproteinases and neurovascular injury]
    J Castillo
    Servicio de Neurologia, Hospital Clinico Universitario, Universidad de Santiago de Compostela
    Neurologia 19:312-20. 2004

Collaborators

Detail Information

Publications63

  1. ncbi [Guidelines for action and diagnosis in atherothrombosis in Spain: ADA Study (Action and Diagnosis in Atherothrombosis)]
    J Castillo
    Servicio de Neurología Hospital Clínico Universitario Santiago de Compostela La Coruna Spain
    Rev Clin Esp 202:202-8. 2002
    ..The ADA Study was designed to know the usual action guidelines in Spain for the diagnosis and treatment in a cohort of patients who had a recent atherothrombotic event...
  2. ncbi Predictors of deteriorating cerebral infarct: role of inflammatory mechanisms. Would its early treatment be useful?
    J Castillo
    Department of Neurology, Hospital Clinico Universitario, University of Santiago de Compostela, Spain
    Cerebrovasc Dis 11:40-8. 2001
    ..It is therefore conceivable that therapeutic interventions aimed at decreasing proinflammatory cytokines and cell adhesion molecules might result in better outcome in this population...
  3. ncbi [Physiopathology of cerebral ischemia]
    J Castillo
    Servicio de Neurologia, Hospital Xeral de Galicia, Universidad de Santiago de Compostela, Espana
    Rev Neurol 30:459-64. 2000
    ..Knowledge of physiopathological mechanisms permits understanding of neuro-imaging changes during the various phases of cerebral ischaemia and the mechanisms of action on which many aspects of treatment are based...
  4. ncbi Molecular signatures of brain injury after intracerebral hemorrhage
    J Castillo
    Department of Neurology, Hospital Clinico Universitario, Santiago de Compostela, Spain
    Neurology 58:624-9. 2002
    ..The mechanisms of cellular death in the tissue surrounding an intracerebral hemorrhage (ICH) are not defined...
  5. ncbi Neuroprotective effects of aspirin in patients with acute cerebral infarction
    Jose Castillo
    Department of Neurology, Hospital Clinico Universitario de Santiago de Compostela, c Travesía da Choupana, s n 15706, Santiago de Compostela, Spain
    Neurosci Lett 339:248-50. 2003
    ..These findings suggest that low doses of aspirin may be useful in the management of patients with cerebral ischemia, not only for its antithrombotic properties, but also by direct neuroprotective effects...
  6. ncbi [Consensus review. Pharmacological neuroprotection in cerebral ischemia: is it still a therapeutic option?]
    J Castillo
    Hospital Clinico Universitario, Santiago de Compostela
    Neurologia 18:368-84. 2003
    ....
  7. ncbi The release of tumor necrosis factor-alpha is associated with ischemic tolerance in human stroke
    Jose Castillo
    Department of Neurology, Hospital Clinico Universitario, University of Santiago de Compostela, Travesa da Choupana s n, 15706 Santiago de Compostela, Spain
    Ann Neurol 54:811-9. 2003
    ..Ischemic tolerance in acute stroke is associated with increased plasma levels of TNF-alpha in the presence of reduced concentrations of IL-6...
  8. ncbi Biochemical changes and inflammatory response as markers for brain ischaemia: molecular markers of diagnostic utility and prognosis in human clinical practice
    Jose Castillo
    Department of Neurology, Hospital Clinico Universitario, Universidad de Santiago de Compostela, Santiago de Compostela, Spain
    Cerebrovasc Dis 17:7-18. 2004
    ..Levels of matrix metalloproteinases-9 (MMP-9) have a significant relationship with the efficacy of thrombolytic treatment and with the incidence and seriousness of haemorrhagic complications...
  9. ncbi Blood pressure decrease during the acute phase of ischemic stroke is associated with brain injury and poor stroke outcome
    Jose Castillo
    Department of Neurology, Hospital Clinico Universitario, University of Santiago de Compostela, Spain
    Stroke 35:520-6. 2004
    ..We explored the association of systolic (SBP) and diastolic (DBP) BP during acute stroke with early neurological deterioration, infarct volume, neurological outcome, and mortality at 3 months...
  10. ncbi [Metalloproteinases and neurovascular injury]
    J Castillo
    Servicio de Neurologia, Hospital Clinico Universitario, Universidad de Santiago de Compostela
    Neurologia 19:312-20. 2004
    ..Combination therapies explicitly involving MMP inhibition could be of value in future treatment strategies...
  11. ncbi Early neurologic deterioration in intracerebral hemorrhage: predictors and associated factors
    R Leira
    Department of Neurology, Hospital Clinico Universitario, Santiago de Compostela
    Neurology 63:461-7. 2004
    ..To identify potential predictors of and factors associated with early neurologic deterioration (END) in primary intracerebral hemorrhage (ICH)...
  12. ncbi [Biochemistry of cerebral ischemia]
    J Castillo
    Servicio de Neurologia, Hospital Xeral de Galicia, Universidad de Santiago de Compostela
    Neurologia 14:17-23. 1999
    ..Knowledge of these mechanisms and the possibility of modifying the chain of events leading to cell death constitute the basis of neuroprotection...
  13. ncbi [Mechanisms of progression of cerebral infarction]
    J Castillo
    Servicio de Neurologia, Complexo Hospitalario Universitario Hospital Xeral de Galicia, Santiago de Compostela
    Neurologia 14:2-12. 1999
    ....
  14. ncbi Timing for fever-related brain damage in acute ischemic stroke
    J Castillo
    Department of Neurology, Complexo Hospitalario Universitario de Santiago Hospital Xeral de Galicia, Barcelona, Spain
    Stroke 29:2455-60. 1998
    ..BACKGROUND and..
  15. doi Inflammation markers and prediction of post-stroke vascular disease recurrence: the MITICO study
    J Castillo
    Dept of Neurology, Clinical Neuroscience Research Laboratory, Hospital Clinico Universitario, 15706 Santiago de Compostela, A Coruna, Spain
    J Neurol 256:217-24. 2009
    ..Vascular disease recurrence following stroke is the main cause of morbidity and mortality. The MITICO study was designed to assess the prognostic value of markers of inflammation in relation to the risk of recurrence of vascular disease...
  16. ncbi Hyperthermia is a surrogate marker of inflammation-mediated cause of brain damage in acute ischaemic stroke
    R Leira
    Department of Neurology, Stroke Unit and Neurovascular Research Laboratory, Hospital Clinico Universitario, Santiago de Compostela, Spain
    J Intern Med 260:343-9. 2006
    ..The objective of this study was to determine, during the acute phase of cerebral ischaemia, the potential relationship between proinflammatory cytokines and hyperthermia as a cause of larger cerebral infarcts...
  17. doi High plasma glutamate concentrations are associated with infarct growth in acute ischemic stroke
    M Castellanos
    Department of Neurosciences, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Ctra de Canyet s n, E 08916 Badalona, Barcelona, Spain
    Neurology 71:1862-8. 2008
    ..Here we investigate whether molecular markers associated with END are related to the volume and outcome of the diffusion weighted image (DWI) lesion in acute ischemic stroke...
  18. ncbi New-onset hypertension and inflammatory response/poor outcome in acute ischemic stroke
    M Rodríguez-Yáñez
    Department of Neurology, Stroke Unit, Hospital Clinico Universitario, University of Santiago de Compostela, Santiago de Compostela, Spain
    Neurology 67:1973-8. 2006
    ..To study the association of previously unknown high blood pressure (HBP) during the acute phase of stroke (new-onset hypertension) with the inflammatory response and clinical outcome...
  19. ncbi Statin treatment withdrawal in ischemic stroke: a controlled randomized study
    M Blanco
    Department of Neurology, Hospital Clinico Universitario, Universidad de Santiago de Compostela, Santiago de Compostela, Spain
    Neurology 69:904-10. 2007
    ..In this controlled randomized study, we investigated the influence of statin pretreatment and its withdrawal on the outcome of acute ischemic stroke patients...
  20. ncbi [Molecular markers are associated with early computed tomography ischemic changes]
    M Rodríguez-Yáñez
    Servicio Neurologia, Laboratorio de Investigación de Neurociencias Clínicas, Hospital Clinico Universitario, Universidad de Santiago de Compostela, Santiago de Compostela, Spain
    Neurologia 23:220-5. 2008
    ..Our objective is to identify molecular markers of neuroexcitotoxicity, neuroinflammation and BBB disruption in the acute phase of stroke that might be associated with early ischemic CT signs...
  21. ncbi Micro- and macroalbuminuria predict hemorrhagic transformation in acute ischemic stroke
    M Rodríguez-Yáñez
    Department of Neurology, Hospital Clinico Universitario, University of Santiago de Compostela, Spain
    Neurology 67:1172-7. 2006
    ..Hemorrhagic transformation (HT) after cerebral ischemia seems to be related to the endothelial disruption secondary to the ischemic process. Albuminuria has recently been found to be a marker of chronic endothelial damage...
  22. doi Association of growth factors with arterial recanalization and clinical outcome in patients with ischemic stroke treated with tPA
    T Sobrino
    Clinical Neuroscience Research Laboratory, Department of Neurology, Hospital Clinico Universitario, University of Santiago de Compostela, Santiago de Compostela, Spain
    J Thromb Haemost 8:1567-74. 2010
    ....
  23. doi Brachial arterial flow mediated dilation in acute ischemic stroke
    D Santos-Garcia
    Department of Neurology, Hospital Clinico Universitario, University of Santiago de Compostela, Santiago de Compostela, Spain
    Eur J Neurol 16:684-90. 2009
    ..FMD is diminished in patients with endothelial dysfunction (ED). Our aim was to investigate the relationship between FMD and outcome for patients with acute ischemic stroke...
  24. pmc Predictors of good outcome in medium to large spontaneous supratentorial intracerebral haemorrhages
    M Castellanos
    Department of Neurology, Hospital Clinico Universitario Santiago de Compostela, Travesa da Choupana s n, Santiago de Compostela 15706, Spain
    J Neurol Neurosurg Psychiatry 76:691-5. 2005
    ..To determine potential predictors of good outcome in primary medium to large intracerebral haemorrhages (ICH) which could be useful for selecting patients for surgical procedures...
  25. doi High serum levels of leptin are associated with post-stroke depression
    I Jimenez
    Department of Neurology, Neuropsychology Laboratory, Clinical Neuroscience Research Laboratory, Hospital Clinico Universitario, University of Santiago de Compostela, Santiago de Compostela, Spain
    Psychol Med 39:1201-9. 2009
    ..Our aim was to test the possible association between inflammatory and neurotrophic molecular markers and the development of post-stroke depression...
  26. doi Increased levels of circulating endothelial progenitor cells in patients with ischaemic stroke treated with statins during acute phase
    T Sobrino
    Clinical Neurosciences Research Laboratory, Department of Neurology, Hospital Clinico Universitario, IDIS, University of Santiago de Compostela, Santiago de Compostela, Spain
    Eur J Neurol 19:1539-46. 2012
    ..Endothelial progenitor cells (EPCs) have been suggested to be a therapeutic option in ischaemic stroke. Our aim was to study whether statin treatment during acute phase could increase circulating EPCs after acute ischaemic stroke...
  27. ncbi [Cognitive impairment associated to leukoaraiosis: its pathophysiology, clinical manifestations and treatment]
    I Jimenez
    Hospital Clinico Universitario, 15706 Santiago de Compostela, Espana
    Rev Neurol 47:536-44. 2008
    ..Clinical manifestations in relation with cognitive functions range from mild affectation to dementia, affecting the processing speed and executive functions...
  28. ncbi An observational study of the effectiveness and safety of natalizumab in the treatment of multiple sclerosis
    A Horga
    Centre d esclerosi multiple de Catalunya, Barcelona, Espana
    Rev Neurol 52:321-30. 2011
    ..To analyse the safety and effectiveness of natalizumab in the treatment of multiple sclerosis in a real clinical practice setting and according to the approved indications...
  29. doi Endothelial dysfunction, vascular disease and stroke: the ARTICO study
    J Roquer
    Servicio de Neurologia, Hospital Universitari del Mar, Barcelona, Spain
    Cerebrovasc Dis 27:25-37. 2009
    ..Data from the ARTICO study will increase the knowledge of patient outcome after ischemic stroke and may help to improve our ability to detect patients at high risk of stroke recurrence or major cardiovascular events...
  30. ncbi Headache as a surrogate marker of the molecular mechanisms implicated in progressing stroke
    R Leira
    Department of Neurology, Hospital Clinico Universitario and Universidad de Santiago de Compostela, Spain
    Cephalalgia 22:303-8. 2002
    ....
  31. ncbi The clinical-DWI mismatch: a new diagnostic approach to the brain tissue at risk of infarction
    A Davalos
    Department of Neurology, Hospital Universitari Doctor Josep Trueta, Girona, Spain
    Neurology 62:2187-92. 2004
    ..To evaluate the usefulness of a mismatch between the severity of acute clinical manifestations and the diffusion-weighted imaging (DWI) lesion in predicting early stroke outcome and infarct volume...
  32. doi Do multimodal evoked potentials add information to MRI in clinically isolated syndromes?
    R Pelayo
    Multiple Sclerosis Center of Catalonia, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain
    Mult Scler 16:55-61. 2010
    ..However, the utility of MMEPs is limited by the low percentage of CIS patients having the three abnormal at baseline...
  33. ncbi [Morbidity due to intracerebral hemorrhage]
    F J López-González
    Servicio de Neurologia, Complexo Hospitalario Universitario de Santiago Hospital Xeral de Galicia, Santiago de Compostela, Espana
    Rev Neurol 27:755-8. 1998
    ..Intracerebral hemorrhage (HIC) represents 10-30% of all stroke. Epidemiological studies have shown factors associated with its high mortality, but those which might lead to lower morbidity are little known...
  34. ncbi [Comparison of hypertensive and non-hypertensive lacunar infarcts]
    P Suarez
    Servicio de Neurologia, Complejo Hospitalaria Universitario Hospital Xeral de Galicia, Santiago de Compostela, Espana
    Rev Neurol 26:807-10; discussion 810-1. 1998
    ..We designed a study to compare the clinical topographic and prognostic characteristics of patients with hypertensive and non-hypertensive lacunar infarcts...
  35. doi Clinical impact of early brain atrophy in clinically isolated syndromes
    F Perez-Miralles
    Multiple Sclerosis Center of Catalonia Cemcat, Hospital Universitari Vall d Hebron, Barcelona, Spain
    Mult Scler 19:1878-86. 2013
    ..The impact of global and tissue-specific brain atrophy on conversion to multiple sclerosis (MS) after a clinically isolated syndrome (CIS) is not fully gauged...
  36. ncbi [3 year survival in patients hospitalized for acute cerebrovascular disorders]
    R Rodriguez
    Servicio de Neurologia, Hospital Xeral de Galicia Clinico Universitario, Santiago de Compostela
    Rev Neurol 24:199-206. 1996
    ..Greater levels of weakness and sphincteral incontinence are the best predictive signs of dependency functional situation at the end of the first month and, along with diabetes, after one and three years...
  37. ncbi [Time for cerebral damage due to hyperglycemia in acute ischemia]
    J Naveiro
    Servicio de Neurologia, Complejo Hospitalario Universitario, Hospital Xeral de Galicia, Santiago de Compostela,
    Rev Neurol 26:790-3. 1998
    ..02; IC 95% = 1.01-1.02). CONCLUSIONS: There is a clear association between hyperglycemia and the worst stage of the infarct, and this is most intense in the first hours after onset of the clinical features...
  38. doi TRPM4 mRNA expression levels in peripheral blood mononuclear cells from multiple sclerosis patients
    S Malhotra
    Department of Neurology Neuroimmunology, Centre d esclerosi multiple de Catalunya, Cemcat, Hospital Universitari Vall d Hebron HUVH, Barcelona, Spain
    J Neuroimmunol 261:146-8. 2013
    ..These findings do not support a role of TRPM4 in the peripheral blood compartment of MS patients...
  39. ncbi [The prognostic value of analytical hemorheological factors in stroke]
    C Suarez
    Servicio de Neurologia, Hospital Xeral de Galicia Complexo Hospitalario Universitario, Santiago de Compostela
    Rev Neurol 24:190-2. 1996
    ....
  40. doi Value of NMO-IgG determination at the time of presentation as CIS
    C Costa
    Unitat de Neuroimmunologia Clinica UNIC, Centre d Esclerosi Mu ltiple de Catalunya, Vall d Hebron Institut de Recerca, Barcelona, Spain
    Neurology 78:1608-11. 2012
    ..Despite the availability of diagnostic criteria, an overlap between neuromyelitis optica (NMO) and multiple sclerosis (MS) exists, particularly in the early stage of the disease...
  41. ncbi [Reorganisation of the cerebral vasculature following ischaemia]
    D Brea
    Laboratorio de Investigación de Neurociencias Clínicas, Servicio de Neurologia, Hospital Clinico de Santiago de Compostela, E 15706 Santiago de Compostela A Coruña, Espana
    Rev Neurol 49:645-54. 2009
    ..Nevertheless, some angiogenic factors such as vascular endothelial growth factor, platelet derived growth factor and angiopoyetin also increase vascular permeability which can produce hemorrhagic transformation...
  42. doi Human recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia
    M Pérez-Mato
    Department of Neurology, Neurovascular ARea, Clinical Neurosciences Research Laboratory, Hospital Clinico Universitario, Health Research Institute of Santiago de Compostela IDIS, University of Santiago de Compostela, Santiago de Compostela, Spain
    Cell Death Dis 5:e992. 2014
    ..In conclusion, our findings indicate that the combination of human rGOT1 with low doses of oxaloacetate seems to be a successful approach for stroke treatment. ..
  43. ncbi [Admission to a hospital with a stroke: the situation at the present time]
    J Castillo
    Complexo Hospitalario Universitario de Santiago, Hospital Xeral de Galicia, Santiago de Compostela, ,
    Rev Neurol 25:1102-4. 1997
    ..CONCLUSION: The objectives of hospitalization in cases of ictus must be defined to optimize care, reduce complications and improve use of health care resources...
  44. doi Metabolic syndrome and resistance to IV thrombolysis in middle cerebral artery ischemic stroke
    J F Arenillas
    Department of Neurosciences, Stroke Unit, Germans Trias i Pujol Universitary Hospital, Universitat Autonoma de Barcelona, Carretera del Canyet, 08916 Badalona, Barcelona, Spain
    Neurology 71:190-5. 2008
    ..We aimed to evaluate the impact of MetS on the response to systemic tPA treatment in patients with acute middle cerebral artery (MCA) ischemic stroke...
  45. ncbi [Comparison of the lesion produced by permanent focal cerebral ischaemia in three animal models using magnetic resonance imaging]
    J Agulla
    Hospital Clinico de Santiago de Compostela, 15706 Santiago de Compostela, Espana
    Rev Neurol 53:265-74. 2011
    ..The perfect animal model that reflects every aspect of stroke pathophysiology does not exist, hence there is a need for a proper selection of the animal model in order to interpret properly the results from experimental research...
  46. ncbi [Imaging techniques for studying functional recovery following a stroke: I. Methodological aspects]
    P Ramos-Cabrer
    Hospital Clinico de Santiago de Compostela, 15706 Santiago de Compostela, Espana
    Rev Neurol 52:355-65. 2011
    ..In the second work we will focus on different practical issues related to the application of the techniques here discussed...
  47. doi Measures in the first year of therapy predict the response to interferon beta in MS
    J Rio
    Unitat de Neuroimmunologia Clinica, Hospital Universitario Vall d Hebron, Barcelona, Spain
    Mult Scler 15:848-53. 2009
    ..Hence, the aim of this study was to investigate magnetic resonance imaging (MRI) and clinical predictors of response during the first 12 months of therapy...
  48. doi Roles of the ubiquitin peptidase USP18 in multiple sclerosis and the response to interferon-β treatment
    S Malhotra
    Servei de Neurologia Neuroimmunologia, Centre d esclerosi múltiple de Catalunya CEM Cat, Hospital Universitari Vall d Hebron HUVH, Barcelona, Spain
    Eur J Neurol 20:1390-7. 2013
    ....
  49. ncbi [Hospital arrival times and delay before acute stroke patients receive neurological care. Analysis of a national multi-centre registry: EPICES registry (II)]
    J Castillo
    Servicio de Neurologia, Hospital Clinico Universitario de Santiago, Universidad de Santiago de Compostela, A Coruna, Espana
    Rev Neurol 54:461-7. 2012
    ..Delays on arrival time and specialized care at hospital are still the first cause that hampers the application of best possible treatments to the stroke patients...
  50. ncbi A chronic treatment with CDP-choline improves functional recovery and increases neuronal plasticity after experimental stroke
    O Hurtado
    Servicio de Neurologia, Hospital Clinico Universitario, Santiago de Compostela, Spain
    Neurobiol Dis 26:105-11. 2007
    ....
  51. ncbi Taurine levels in plasma and cerebrospinal fluid in migraine patients
    F Martinez
    Department of Neurology, Hospital General de Galicia, Clinico Universitario, Santiago de Compostela, Spain
    Headache 33:324-7. 1993
    ..Central taurine liberation during migraine crisis may be due to spontaneous depolarization or a defensive reaction in the context of cerebral homeostatic processes...
  52. doi [Stroke health care plan (ICTUS II. 2010)]
    J Masjuan
    Servicio de Neurologia, Hospital Universitario Ramon y Cajal, Madrid, Espana
    Neurologia 26:383-96. 2011
    ..This Plan needs to be updated in order to introduce new developments in acute stroke...
  53. ncbi [Hospital mortality in ischemia: influence of two vascular risk factors]
    F J López-González
    Servicio de Neurologia, Complexo Hospitalario Universitario de Santiago Hospital Xeral de Galicia, Santiago de Compostela, Espana
    Rev Neurol 27:473-7. 1998
    ..Most studies are in agreement that advanced age, type of ictus, size of lesion and clinical deterioration are factors determining mortality. However, its relationship to vascular risk factors is not completely clear...
  54. doi The natural tissue plasminogen activator inhibitor neuroserpin and acute ischaemic stroke outcome
    Raquel Rodríguez-González
    Department of Neurology, Hospital Clinico Universitario, Universidad de Santiago de Compostela, Santiago de Compostela, Spain
    Thromb Haemost 105:421-9. 2011
    ..These findings support the concept that neuroserpin might play an important role during cerebral ischaemia...
  55. ncbi [Is necessary to perform a transthoracic echocardiogram in all the patients with cryptogenic stroke during hospitalization?]
    Susana Arias-Rivas
    Unidad de Ictus, Servicio de Neurologia, Area de Neurociencias
    Rev Neurol 56:510-4. 2013
    ..The absence of official recommendations for the use of echocardiography in patients with ischemic stroke leads to a universal application showing low diagnostic efficiency...
  56. ncbi Plasma monoamines in tension-type headache
    J Castillo
    Department of Neurology, Hospital General de Galicia, , Santiago de Compostela, Spain
    Headache 34:531-5. 1994
    ..These alterations seem to be independent from the underlying depression and related to the pathophysiologic mechanisms of headache...
  57. ncbi [Epidemiology of the subtypes of stroke in hospitalised patients attended by neurologists: results of the EPICES registry (I)]
    S Arias-Rivas
    Servicio de Neurologia, Hospital Clinico Universitario, Travesa da Choupana, s n E 15706 Santiago de Compostela, Espana
    Rev Neurol 54:385-93. 2012
    ..The major stroke subtypes have different patterns of incidence and outcome, for that reason information on the natural history of stroke subtypes is essential...
  58. ncbi [Biomarkers and PET for assessing the activity of Takayasu's arteritis]
    X Rodriguez-Osorio
    Servicio de Neurología y Laboratorio de Investigación en Neurociencias Clínicas, Hospital Clinico Universitario, Universidad de Santiago de Compostela, Santiago de Compostela, Spain
    Neurologia 23:329-32. 2008
    ..Inflammatory stages occur during the course of the disease. Angiography remains the gold standard examination of choice but less invasive techniques are needed to assess the activity of the disease and to monitor response to treatment...
  59. ncbi [Plan for stroke healthcare delivery]
    J Alvarez Sabin
    Servicio de Neurologia, Hospital Universitario Vall d Hebron, Barcelona
    Neurologia 21:717-26. 2006
    ..All stroke patients should receive the same degree of specialized healthcare attention according to the stage of their disease, independently of where they live, their age, gender or ethnicity...
  60. doi Recommendations guide for experimental animal models in stroke research
    L Garcia-Bonilla
    Laboratorio de Investigación Neurovascular, Institut de Recerca Vall d Hebron, Hospital Universitario Vall d Hebron, Universidad Autonoma de Barcelona, Barcelona, Spain
    Neurologia 26:105-10. 2011
    ..Some pitfalls in clinical trials might have their origins in the pre-clinical experimental ischaemic models for the evaluation of potential neuro-protective agents...
  61. ncbi [Adding lamotrigine to the treatment of epilepsy which is difficult to control]
    P Suarez
    Servicio de Neurologia, Hospital General de Galicia, Clinico Universitario, Santiago de Compostela
    Rev Neurol 23:1190-2. 1995
    ..Two patients gave up other drugs and continued monotherapy using Lamotrigine. In nine of the ten Lennox-Gastaut syndrome patients the frequency of attacks went down by more than 50% and in seven such cases by more than 75%...
  62. ncbi [Application of proteomics to neurological diseases]
    D Brea
    Laboratorio de Investigación Neurovascular, Hospital Clinico Universitario, Universidad de Santiago de Compostela, Santiado de Compostela
    Neurologia 22:170-9. 2007
    ..Subsequently, validation of these markers may help to identify new diagnostic and therapeutic targets...
  63. ncbi [Compliance with the measures for preventing vascular risk factors in hospitalised patients with acute stroke. Analysis of a national multi-centre registry: EPICES registry (III)]
    Miguel Blanco
    Servicio de Neurologia, Instituto de Investigaciones Sanitarias de Santiago, IDIS, Hospital Clinico Universitario, Universidad de Santiago de Compostela, Santiago de Compostela, A Coruna, Espana
    Rev Neurol 54:523-9. 2012
    ..Pharmacological and dietary measurements, as well as life style, to control risk factors are efficient procedures to prevent cerebrovascular diseases, though their implementation in the clinics seems not optimal...