Jorge Amigo

Summary

Affiliation: Santiago de Compostela
Country: Spain

Publications

  1. pmc The impact of modern migrations on present-day multi-ethnic Argentina as recorded on the mitochondrial DNA genome
    María Laura Catelli
    Equipo Argentino de Antropología Forense, Independencia 644 5C, Edif EME1, Cordoba, Argentina
    BMC Genet 12:77. 2011
  2. pmc SPSmart: adapting population based SNP genotype databases for fast and comprehensive web access
    Jorge Amigo
    Spanish National Genotyping Center CeGen, Genomic Medicine Group, CIBERER, University of Santiago de Compostela, Galicia, Spain
    BMC Bioinformatics 9:428. 2008
  3. pmc Viability of in-house datamarting approaches for population genetics analysis of SNP genotypes
    Jorge Amigo
    Spanish National Genotyping Center CeGen, Genomic Medicine Group, CIBERER, University of Santiago de Compostela, Galicia, Spain
    BMC Bioinformatics 10:S5. 2009
  4. pmc ENGINES: exploring single nucleotide variation in entire human genomes
    Jorge Amigo
    Grupo de Medicina Xenómica, CIBERER, Universidade de Santiago de Compostela, Santiago de Compostela, Galicia, Spain
    BMC Bioinformatics 12:105. 2011
  5. doi Resequencing and association analysis of coding regions at twenty candidate genes suggest a role for rare risk variation at AKAP9 and protective variation at NRXN1 in schizophrenia susceptibility
    Jose Javier Suárez-Rama
    Instituto de Investigación Sanitaria IDIS de Santiago de Compostela, Complexo Hospitalario Universitario de Santiago CHUS, Servizo Galego de Saude SERGAS, Santiago de Compostela, Spain Grupo de Medicina Xenómica, Universidade de Santiago de Compostela, Santiago de Compostela, Spain
    J Psychiatr Res 66:38-44. 2015
  6. doi The SNPforID browser: an online tool for query and display of frequency data from the SNPforID project
    Jorge Amigo
    Spanish National Genotyping Center CeGen and Genomic Medicine Group, CIBERER, University of Santiago de Compostela, Santiago de Compostela, Spain
    Int J Legal Med 122:435-40. 2008
  7. pmc Mitogenomes from The 1000 Genome Project reveal new Near Eastern features in present-day Tuscans
    Alberto Gómez-Carballa
    Unidade de Xenetica, Departamento de Anatomía Patolóxica e Ciencias Forenses, and Instituto de Ciencias Forenses, Facultade de Medicina, Universidade de Santiago de Compostela, 15872, Galicia, Spain Grupo de investigación en Genética, Vacunas, Infecciones y Pediatría GENVIP, Hospital Clínico Universitario and Universidade de Santiago de Compostela USC, Galicia, Spain
    PLoS ONE 10:e0119242. 2015
  8. pmc A reduced number of mtSNPs saturates mitochondrial DNA haplotype diversity of worldwide population groups
    Antonio Salas
    Unidade de Xenetica, Departamento de Anatomía Patolóxica e Ciencias Forenses, Universidade de Santiago de Compostela, Galicia, Spain
    PLoS ONE 5:e10218. 2010
  9. doi Next generation sequencing challenges in the analysis of cardiac sudden death due to arrhythmogenic disorders
    Maria Brion
    Grupo de Xenética de enfermidades cardiovasculares e oftalmolóxicas, IDIS, RIC Santiago de Compostela, Spain Fundación Pública Galega de Medicina Xenómica, SERGAS, Santiago de Compostela, Spain
    Electrophoresis 35:3111-6. 2014
  10. pmc A genome-wide study of modern-day Tuscans: revisiting Herodotus's theory on the origin of the Etruscans
    Jacobo Pardo-Seco
    Unidade de Xenetica, Departamento de Anatomía Patolóxica e Ciencias Forenses, and Instituto de Ciencias Forenses, Grupo de Medicina Xenómica GMX, Facultade de Medicina, Universidade de Santiago de Compostela, Galicia, Spain Grupo de investigación en Genética, Vacunas, Infecciones y Pediatría GENVIP, Hospital Clínico Universitario and Universidade de Santiago de Compostela USC, Galicia, Spain
    PLoS ONE 9:e105920. 2014

Collaborators

  • Antonio Salas
  • Christopher Phillips
  • Javier Costas
  • Angel Carracedo
  • Julio Rodriguez-Lopez
  • Jacobo Pardo-Seco
  • Alberto Gómez-Carballa
  • Maria Brion
  • Beatriz Sobrino
  • Jose Javier Suárez-Rama
  • Federico Martinon-Torres
  • Emilia Balboa-Beltran
  • María Laura Catelli
  • Mario Páramo
  • Eduardo Paz
  • Julio Brenlla
  • Santiago Agra
  • Manuel Arrojo
  • Alejandro Pérez-Muñuzuri
  • Rocio Gil
  • Marina Martinez
  • Montserrat Santori
  • Alejandro Blanco-Verea
  • Francisco Barros
  • Eva Ramos-Luis
  • Carlos García-Magán
  • Maria L Couce
  • María J Fernández-Seara
  • Ramón Lago
  • Wenceslao Gonzãlez-Manteiga
  • Ana Mosquera-Miguel
  • Carlos Vullo
  • Carola Romanini
  • Alicia Borosky
  • Vanesa Alvarez-Iglesias

Detail Information

Publications13

  1. pmc The impact of modern migrations on present-day multi-ethnic Argentina as recorded on the mitochondrial DNA genome
    María Laura Catelli
    Equipo Argentino de Antropología Forense, Independencia 644 5C, Edif EME1, Cordoba, Argentina
    BMC Genet 12:77. 2011
    ..A worldwide database was used for phylogeographic inferences, inter-population comparisons, and admixture analysis. Samples identified as belonging to hg (hg) H2a5 were sequenced for the entire mtDNA genome...
  2. pmc SPSmart: adapting population based SNP genotype databases for fast and comprehensive web access
    Jorge Amigo
    Spanish National Genotyping Center CeGen, Genomic Medicine Group, CIBERER, University of Santiago de Compostela, Galicia, Spain
    BMC Bioinformatics 9:428. 2008
    ....
  3. pmc Viability of in-house datamarting approaches for population genetics analysis of SNP genotypes
    Jorge Amigo
    Spanish National Genotyping Center CeGen, Genomic Medicine Group, CIBERER, University of Santiago de Compostela, Galicia, Spain
    BMC Bioinformatics 10:S5. 2009
    ..While many of these SNP repositories have implemented data retrieval tools for general-purpose mining, these alone cannot cover the broad spectrum of needs of most medical and population genetics studies...
  4. pmc ENGINES: exploring single nucleotide variation in entire human genomes
    Jorge Amigo
    Grupo de Medicina Xenómica, CIBERER, Universidade de Santiago de Compostela, Santiago de Compostela, Galicia, Spain
    BMC Bioinformatics 12:105. 2011
    ....
  5. doi Resequencing and association analysis of coding regions at twenty candidate genes suggest a role for rare risk variation at AKAP9 and protective variation at NRXN1 in schizophrenia susceptibility
    Jose Javier Suárez-Rama
    Instituto de Investigación Sanitaria IDIS de Santiago de Compostela, Complexo Hospitalario Universitario de Santiago CHUS, Servizo Galego de Saude SERGAS, Santiago de Compostela, Spain Grupo de Medicina Xenómica, Universidade de Santiago de Compostela, Santiago de Compostela, Spain
    J Psychiatr Res 66:38-44. 2015
    ..These data suggest a role of rare missense variants at NRXN1 and AKAP9 in schizophrenia susceptibility, probably related to alteration of the excitatory/inhibitory synaptic balance, deserving further investigation...
  6. doi The SNPforID browser: an online tool for query and display of frequency data from the SNPforID project
    Jorge Amigo
    Spanish National Genotyping Center CeGen and Genomic Medicine Group, CIBERER, University of Santiago de Compostela, Santiago de Compostela, Spain
    Int J Legal Med 122:435-40. 2008
    ..The interface has been designed to offer the useful facility of combining populations into appropriate geographic groups for visual comparison of populations individually or amongst user-defined groupings and with equivalent HapMap data...
  7. pmc Mitogenomes from The 1000 Genome Project reveal new Near Eastern features in present-day Tuscans
    Alberto Gómez-Carballa
    Unidade de Xenetica, Departamento de Anatomía Patolóxica e Ciencias Forenses, and Instituto de Ciencias Forenses, Facultade de Medicina, Universidade de Santiago de Compostela, 15872, Galicia, Spain Grupo de investigación en Genética, Vacunas, Infecciones y Pediatría GENVIP, Hospital Clínico Universitario and Universidade de Santiago de Compostela USC, Galicia, Spain
    PLoS ONE 10:e0119242. 2015
    ..For phylogeographic and evolutionary analysis we made use of a large worldwide database of entire mitogenomes (>26,000) and partial control region sequences (>180,000)...
  8. pmc A reduced number of mtSNPs saturates mitochondrial DNA haplotype diversity of worldwide population groups
    Antonio Salas
    Unidade de Xenetica, Departamento de Anatomía Patolóxica e Ciencias Forenses, Universidade de Santiago de Compostela, Galicia, Spain
    PLoS ONE 5:e10218. 2010
    ..Applications of the selected mtSNP panel range from anthropologic and medical studies to forensic genetic casework...
  9. doi Next generation sequencing challenges in the analysis of cardiac sudden death due to arrhythmogenic disorders
    Maria Brion
    Grupo de Xenética de enfermidades cardiovasculares e oftalmolóxicas, IDIS, RIC Santiago de Compostela, Spain Fundación Pública Galega de Medicina Xenómica, SERGAS, Santiago de Compostela, Spain
    Electrophoresis 35:3111-6. 2014
    ..In conclusion, NGS allowed us to accurately detect arrhythmogenic disease causing mutations in a fast and cost-efficient manner that is suitable for daily clinical and forensic practice of genetic testing of this type of disorders. ..
  10. pmc A genome-wide study of modern-day Tuscans: revisiting Herodotus's theory on the origin of the Etruscans
    Jacobo Pardo-Seco
    Unidade de Xenetica, Departamento de Anatomía Patolóxica e Ciencias Forenses, and Instituto de Ciencias Forenses, Grupo de Medicina Xenómica GMX, Facultade de Medicina, Universidade de Santiago de Compostela, Galicia, Spain Grupo de investigación en Genética, Vacunas, Infecciones y Pediatría GENVIP, Hospital Clínico Universitario and Universidade de Santiago de Compostela USC, Galicia, Spain
    PLoS ONE 9:e105920. 2014
    ..The bulk of the information has been reconstructed from ancient texts and archaeological findings and, in the last few years, through the analysis of uniparental genetic markers...
  11. pmc A generalized model to estimate the statistical power in mitochondrial disease studies involving 2×k tables
    Jacobo Pardo-Seco
    Unidade de Xenetica, Departamento de Anatomía Patolóxica e Ciencias Forenses, and Instituto de Ciencias Forenses, Grupo de Medicina Xenómica GMX, Facultade de Medicina, Universidade de Santiago de Compostela, Galicia, Spain
    PLoS ONE 8:e73567. 2013
    ..haplogroups) has been analyzed in regards to a number of multifactorial diseases. The statistical power of a case-control study determines the a priori probability to reject the null hypothesis of homogeneity between cases and controls...
  12. doi An efficient screening method for simultaneous detection of recurrent copy number variants associated with psychiatric disorders
    Julio Rodriguez-Lopez
    Instituto de Investigación Sanitaria IDIS de Santiago de Compostela, Servizo Galego de Saude SERGAS, Santiago de Compostela, Spain Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain
    Clin Chim Acta 445:34-40. 2015
    ..The method may be very useful for management of psychiatric patients as well as screening of different collections of samples to better identify the full spectrum of clinical variability. ..
  13. doi A novel stop mutation in the vascular endothelial growth factor-C gene (VEGFC) results in Milroy-like disease
    Emilia Balboa-Beltran
    Fundacion Publica Galega de Medicina Xenomica, SERGAS, Santiago de Compostela, Spain
    J Med Genet 51:475-8. 2014
    ..The only genetic alteration known to be associated with Milroy-like disease was recently identified in a family with a frameshift mutation in vascular endothelial growth factor C (VEGFC) gene, which encodes a VEGFR3 ligand...