Isaac Salazar-Ciudad

Summary

Country: Spain

Publications

  1. ncbi request reprint Looking at the origin of phenotypic variation from pattern formation gene networks
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, FIN 00014, University of Helsinki, Helsinki, Finland
    J Biosci 34:573-87. 2009
  2. doi request reprint Evolution in biological and nonbiological systems under different mechanisms of generation and inheritance
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, University of Helsinki, 00014, Helsinki, Finland
    Theory Biosci 127:343-58. 2008
  3. doi request reprint A two level mutation-selection model of cultural evolution and diversity
    Isaac Salazar-Ciudad
    Genomics, Bioinformatics and Evolution Group, Genetics and Microbiology Department, Facultat de Biociències Edifici C, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    J Theor Biol 267:171-85. 2010
  4. doi request reprint A computational model of teeth and the developmental origins of morphological variation
    Isaac Salazar-Ciudad
    Departament de Genetica i Microbiologia, Facultat de Biociencies, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Nature 464:583-6. 2010
  5. doi request reprint Adaptive dynamics under development-based genotype-phenotype maps
    Isaac Salazar-Ciudad
    Evolutionary phenomics group Developmental Biology Program, Institute of Biotechnology, University of Helsinki, PO Box 56, FIN 00014 Helsinki, Finland
    Nature 497:361-4. 2013
  6. doi request reprint Morphological evolution and embryonic developmental diversity in metazoa
    Isaac Salazar-Ciudad
    Grup de Genòmica, Bioinformàtica i Evolució, Departament de Genetica i Microbiologia, Universitat Autonoma de Barcelona, Cerdanyola del Valles, Spain
    Development 137:531-9. 2010
  7. ncbi request reprint The economy of tinkering mammalian teeth
    Jukka Jernvall
    Developmental Biology Program, Institute of Biotechnology, Viikki Biocenter, P O Box 56, University of Helsinki, FIN 00014, Helsinki, Finland
    Novartis Found Symp 284:207-16; discussion 216-24. 2007
  8. ncbi request reprint Graduality and innovation in the evolution of complex phenotypes: insights from development
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, FIN 00014, University of Helsinki, Helsinki, Finland
    J Exp Zool B Mol Dev Evol 304:619-31. 2005
  9. ncbi request reprint Mechanisms of pattern formation in development and evolution
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, PO Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
    Development 130:2027-37. 2003
  10. ncbi request reprint How different types of pattern formation mechanisms affect the evolution of form and development
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, P O Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
    Evol Dev 6:6-16. 2004

Detail Information

Publications15

  1. ncbi request reprint Looking at the origin of phenotypic variation from pattern formation gene networks
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, FIN 00014, University of Helsinki, Helsinki, Finland
    J Biosci 34:573-87. 2009
    ..Re-use leads to extensive modularity in gene networks while developmental drift blurs this modularity. Evolutionary opportunism makes developmental gene networks very dependent on epigenetic factors...
  2. doi request reprint Evolution in biological and nonbiological systems under different mechanisms of generation and inheritance
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, University of Helsinki, 00014, Helsinki, Finland
    Theory Biosci 127:343-58. 2008
    ....
  3. doi request reprint A two level mutation-selection model of cultural evolution and diversity
    Isaac Salazar-Ciudad
    Genomics, Bioinformatics and Evolution Group, Genetics and Microbiology Department, Facultat de Biociències Edifici C, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    J Theor Biol 267:171-85. 2010
    ..This study suggests that a larger interchange of cultural traits between populations could lead to cultural evolution not improving the adaptation of individuals to their environment and to a decrease of cultural diversity...
  4. doi request reprint A computational model of teeth and the developmental origins of morphological variation
    Isaac Salazar-Ciudad
    Departament de Genetica i Microbiologia, Facultat de Biociencies, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Nature 464:583-6. 2010
    ..Our study provides a step towards integrating the genotype, development and the phenotype...
  5. doi request reprint Adaptive dynamics under development-based genotype-phenotype maps
    Isaac Salazar-Ciudad
    Evolutionary phenomics group Developmental Biology Program, Institute of Biotechnology, University of Helsinki, PO Box 56, FIN 00014 Helsinki, Finland
    Nature 497:361-4. 2013
    ..The results contribute developmental understanding to the long-standing question of which aspects of phenotype can be effectively optimized by natural selection...
  6. doi request reprint Morphological evolution and embryonic developmental diversity in metazoa
    Isaac Salazar-Ciudad
    Grup de Genòmica, Bioinformàtica i Evolució, Departament de Genetica i Microbiologia, Universitat Autonoma de Barcelona, Cerdanyola del Valles, Spain
    Development 137:531-9. 2010
    ....
  7. ncbi request reprint The economy of tinkering mammalian teeth
    Jukka Jernvall
    Developmental Biology Program, Institute of Biotechnology, Viikki Biocenter, P O Box 56, University of Helsinki, FIN 00014, Helsinki, Finland
    Novartis Found Symp 284:207-16; discussion 216-24. 2007
    ..These kinds of developmentally influenced tendencies may be hypothesized to be typical to many organs and systems showing repeated evolutionary patterns...
  8. ncbi request reprint Graduality and innovation in the evolution of complex phenotypes: insights from development
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, FIN 00014, University of Helsinki, Helsinki, Finland
    J Exp Zool B Mol Dev Evol 304:619-31. 2005
    ..This work also explores further consequences of these results in our understanding of phenotypic evolution...
  9. ncbi request reprint Mechanisms of pattern formation in development and evolution
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, PO Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
    Development 130:2027-37. 2003
    ....
  10. ncbi request reprint How different types of pattern formation mechanisms affect the evolution of form and development
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, P O Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
    Evol Dev 6:6-16. 2004
    ..In addition, type of mechanism affects the tempo and mode of morphological evolution. These results suggest that the basic principles by which development is organized can influence the likelihood of morphological evolution...
  11. ncbi request reprint Developmental constraints vs. variational properties: How pattern formation can help to understand evolution and development
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, FIN 00014, University of Helsinki, Helsinki, Finland
    J Exp Zool B Mol Dev Evol 306:107-25. 2006
    ..That is what kind of pattern formation mechanisms, in which relative temporal order, and which kind of phenotypic changes, are expected to be found in development...
  12. doi request reprint Tooth patterning and evolution
    Isaac Salazar-Ciudad
    Evolutionary Phenomics Group, Developmental Biology Program, Institute of Biotechnology, University of Helsinki, Helsinki, Finland
    Curr Opin Genet Dev 22:585-92. 2012
    ..Those are discussed here since they provide clues about how reaction-diffusion systems may work in actual developmental systems. Mathematical models implementing what we know about tooth development are discussed...
  13. ncbi request reprint On the origins of morphological disparity and its diverse developmental bases
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, PO Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
    Bioessays 28:1112-22. 2006
    ..Some specific examples of these kinds of morphologic changes are explained...
  14. pmc Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling
    Elina Järvinen
    Developmental Biology Program, Institute of Biotechnology, Viikki Biocenter, P O Box 56, University of Helsinki, FIN 00014 Helsinki, Finland
    Proc Natl Acad Sci U S A 103:18627-32. 2006
    ..These results may implicate Wnt signaling in tooth renewal, a capacity that was all but lost when mammals evolved progressively more complicated tooth shapes...
  15. ncbi request reprint Tooth morphogenesis in vivo, in vitro, and in silico
    Isaac Salazar-Ciudad
    Developmental Biology Program, Institute of Biotechnology, P O Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
    Curr Top Dev Biol 81:341-71. 2008
    ..Overall, this review should be interesting to either readers interested in the mechanistic bases of tooth morphogenesis, without necessarily being interested in modeling per se, and readers interested in development modeling in general...