Research Topics
Genomes and GenesSpecies | Isaac Salazar-CiudadSummaryCountry: Spain Publications
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Detail Information
Publications
Looking at the origin of phenotypic variation from pattern formation gene networksIsaac Salazar-Ciudad
Developmental Biology Program, Institute of Biotechnology, FIN 00014, University of Helsinki, Helsinki, Finland
J Biosci 34:573-87. 2009..Re-use leads to extensive modularity in gene networks while developmental drift blurs this modularity. Evolutionary opportunism makes developmental gene networks very dependent on epigenetic factors...
Evolution in biological and nonbiological systems under different mechanisms of generation and inheritanceIsaac Salazar-Ciudad
Developmental Biology Program, Institute of Biotechnology, University of Helsinki, 00014, Helsinki, Finland
Theory Biosci 127:343-58. 2008....
A computational model of teeth and the developmental origins of morphological variationIsaac Salazar-Ciudad
Departament de Genetica i Microbiologia, Facultat de Biociencies, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
Nature 464:583-6. 2010..Our study provides a step towards integrating the genotype, development and the phenotype...
A two level mutation-selection model of cultural evolution and diversityIsaac Salazar-Ciudad
Genomics, Bioinformatics and Evolution Group, Genetics and Microbiology Department, Facultat de Biociències Edifici C, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
J Theor Biol 267:171-85. 2010..This study suggests that a larger interchange of cultural traits between populations could lead to cultural evolution not improving the adaptation of individuals to their environment and to a decrease of cultural diversity...
Morphological evolution and embryonic developmental diversity in metazoaIsaac Salazar-Ciudad
Grup de Genòmica, Bioinformàtica i Evolució, Departament de Genetica i Microbiologia, Universitat Autonoma de Barcelona, Cerdanyola del Valles, Spain
Development 137:531-9. 2010....
Graduality and innovation in the evolution of complex phenotypes: insights from developmentIsaac Salazar-Ciudad
Developmental Biology Program, Institute of Biotechnology, FIN 00014, University of Helsinki, Helsinki, Finland
J Exp Zool B Mol Dev Evol 304:619-31. 2005..This work also explores further consequences of these results in our understanding of phenotypic evolution...
Mechanisms of pattern formation in development and evolutionIsaac Salazar-Ciudad
Developmental Biology Program, Institute of Biotechnology, PO Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
Development 130:2027-37. 2003....
How different types of pattern formation mechanisms affect the evolution of form and developmentIsaac Salazar-Ciudad
Developmental Biology Program, Institute of Biotechnology, P O Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
Evol Dev 6:6-16. 2004..In addition, type of mechanism affects the tempo and mode of morphological evolution. These results suggest that the basic principles by which development is organized can influence the likelihood of morphological evolution...
Developmental constraints vs. variational properties: How pattern formation can help to understand evolution and developmentIsaac Salazar-Ciudad
Developmental Biology Program, Institute of Biotechnology, FIN 00014, University of Helsinki, Helsinki, Finland
J Exp Zool B Mol Dev Evol 306:107-25. 2006..That is what kind of pattern formation mechanisms, in which relative temporal order, and which kind of phenotypic changes, are expected to be found in development...
The economy of tinkering mammalian teethJukka Jernvall
Developmental Biology Program, Institute of Biotechnology, Viikki Biocenter, P O Box 56, University of Helsinki, FIN 00014, Helsinki, Finland
Novartis Found Symp 284:207-16; discussion 216-24. 2007..These kinds of developmentally influenced tendencies may be hypothesized to be typical to many organs and systems showing repeated evolutionary patterns...
Tooth morphogenesis in vivo, in vitro, and in silicoIsaac Salazar-Ciudad
Developmental Biology Program, Institute of Biotechnology, P O Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
Curr Top Dev Biol 81:341-71. 2008..Overall, this review should be interesting to either readers interested in the mechanistic bases of tooth morphogenesis, without necessarily being interested in modeling per se, and readers interested in development modeling in general...
On the origins of morphological disparity and its diverse developmental basesIsaac Salazar-Ciudad
Developmental Biology Program, Institute of Biotechnology, PO Box 56, FIN 00014, University of Helsinki, Helsinki, Finland
Bioessays 28:1112-22. 2006..Some specific examples of these kinds of morphologic changes are explained...
Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signalingElina Järvinen
Developmental Biology Program, Institute of Biotechnology, Viikki Biocenter, P O Box 56, University of Helsinki, FIN 00014 Helsinki, Finland
Proc Natl Acad Sci U S A 103:18627-32. 2006..These results may implicate Wnt signaling in tooth renewal, a capacity that was all but lost when mammals evolved progressively more complicated tooth shapes...
