Research Topics
| Inaki Ruiz-TrilloSummaryCountry: Spain Publications
| Collaborators
|
Detail Information
Publications
Evolution of the MAGUK protein gene family in premetazoan lineagesAlex de Mendoza
Departament de Genetica, Universitat de Barcelona, Barcelona, Spain
BMC Evol Biol 10:93. 2010..To further investigate the evolutionary history of MAGUK, we have undertook a broader search for this gene family using available genomic sequences of different opisthokont taxa...
A phylogenomic investigation into the origin of metazoaInaki Ruiz-Trillo
Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Canada
Mol Biol Evol 25:664-72. 2008..Understanding the function of "metazoan-specific" proteins we have identified in these protists will clarify the evolutionary steps that led to the emergence of the Metazoa...
New genomes, new taxa and deep questions in the eukaryotic tree of life: a meeting report on the EMBO comparative genomics conferenceAlex de Mendoza
Institut de Biologia Evolutiva UPF CSIC, Passeig Marítim de la Barceloneta 37 49, 08003 Barcelona, Spain
Evodevo 2:22. 2011..ABSTRACT: A report on the meeting Comparative Genomics of Eukaryotic Microorganisms: understanding the complexity of diversity. Sant Feliu de Guíxols, Spain. October 15-20, 2011...
Unexpected repertoire of metazoan transcription factors in the unicellular holozoan Capsaspora owczarzakiArnau Sebé-Pedrós
Departament de Genètica and Institut de Recerca en Biodiversitat Irbio, Universitat de Barcelona, Barcelona, Spain
Mol Biol Evol 28:1241-54. 2011..Nonetheless, TF families whose beginnings antedate the origin of the animal kingdom, such as homeodomain or basic helix-loop-helix, underwent significant expansion and diversification along metazoan and eumetazoan stems...
Genomic survey of premetazoans shows deep conservation of cytoplasmic tyrosine kinases and multiple radiations of receptor tyrosine kinasesHiroshi Suga
Institut de Biologia Evolutiva UPF CSIC, Passeig Marítim de la Barceloneta 37 49, 08003 Barcelona, Spain
Sci Signal 5:ra35. 2012....
The mysterious evolutionary origin for the GNE gene and the root of bilateriaAlex de Mendoza
Departament de Genetica, Universitat de Barcelona, Barcelona, Spain
Mol Biol Evol 28:2987-91. 2011..However, rather than using GNE as a phylogenetic character, we argue that rare genomic changes such as the one presented here should be used with caution...
Phylogenetic relationships within the Opisthokonta based on phylogenomic analyses of conserved single-copy protein domainsGuifré Torruella
Departament de Genètica and Institut de Recerca en Biodiversitat Irbio, Universitat de Barcelona, Barcelona, Spain
Mol Biol Evol 29:531-44. 2012..These results represent independent tests of previous phylogenetic hypotheses, highlighting the importance of sophisticated approaches for orthology assignment in phylogenomic analyses...
Ancient origin of the integrin-mediated adhesion and signaling machineryArnau Sebé-Pedrós
Departament de Genètica and Institut de Recerca en Biodiversitat, Universitat de Barcelona, 08028 Barcelona, Spain
Proc Natl Acad Sci U S A 107:10142-7. 2010..This underscores the importance of gene cooption in the unicellular-to-multicellular transition that led to the emergence of the Metazoa...
Phylogenomic evidence for a myxococcal contribution to the mitochondrial fatty acid beta-oxidationAgatha Schluter
Neurometabolic Diseases Laboratory, Institut d Investigació Biomèdica de Bellvitge IDIBELL, L Hospitalet de Llobregat, Barcelona, Spain
PLoS ONE 6:e21989. 2011..The growing availability of microbial genomes offers the possibility of analyzing the ancestry of eukaryotic genomes and testing previous hypotheses on their origins...
The evolutionary history of lysine biosynthesis pathways within eukaryotesGuifré Torruella
Departament de Genètica and Institut de Recerca en Biodiversitat Irbio, Universitat de Barcelona, Barcelona, Spain
J Mol Evol 69:240-8. 2009..Overall, these observations represent new evidence that the role of LGT in the evolutionary history of eukaryotes may have been more significant than previously thought...
Insights into the evolutionary origin and genome architecture of the unicellular opisthokonts Capsaspora owczarzaki and Sphaeroforma arcticaInaki Ruiz-Trillo
Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS, Canada B3H 1X5
J Eukaryot Microbiol 53:379-84. 2006..Finally, to begin characterizing the Capsaspora genome, we have performed pulsed-field gel electrophoresis (PFGE) analyses, which indicate that its genome has at least 12 chromosomes with a total genome size in the range of 22-25 Mb...
Sawyeria marylandensis (Heterolobosea) has a hydrogenosome with novel metabolic propertiesMaria José Barberà
Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS, Canada
Eukaryot Cell 9:1913-24. 2010..Overall, these data suggest that Sawyeria marylandensis possesses a hydrogenosome of mitochondrial origin with a novel combination of biochemical and structural properties...
