Research Topics
| Ana RuigómezSummaryCountry: Spain Publications
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Publications
Gastroesophageal reflux disease in primary care: using changes in proton pump inhibitor therapy as an indicator of partial responseAna Ruigómez
Spanish Centre for Pharmacoepidemiologic Research CEIFE, Madrid, Spain
Scand J Gastroenterol 47:751-61. 2012..We aimed to characterize partial response to PPIs among adult patients in UK primary care...
Risk of cerebrovascular accident after a first diagnosis of atrial fibrillationAna Ruigómez
Spanish Centre for Pharmacoepidemiological Research CEIFE, Madrid, Spain
Clin Cardiol 30:624-8. 2007..Atrial fibrillation is the most common cardiac arrhythmia and a major risk factor for cerebrovascular accident, including ischemic stroke and transient ischemic attack...
Endoscopic findings in a cohort of newly diagnosed gastroesophageal reflux disease patients registered in a UK primary care databaseA Ruigomez
Centro Español de Investigación Farmacoepidemiológica CEIFE, Madrid, Spain
Dis Esophagus 21:251-6. 2008..Male gender, increasing age and a history of bleeding were risk factors for esophageal complications...
Risk of cardiovascular and cerebrovascular events after atrial fibrillation diagnosisAna Ruigómez
Spanish Centre for Pharmacoepidemiological Research CEIFE, Madrid, Spain
Int J Cardiol 136:186-92. 2009..This study aimed to evaluate the risk of ischemic cerebrovascular events (ICVE), coronary events (CE) or heart failure (HF) following a diagnosis of AF...
Irritable bowel syndrome and gastroesophageal reflux disease in primary care: is there a link?Ana Ruigómez
Spanish Centre for Pharmacoepidemiological Research CEIFE, Almirante 28, 2 masculine, 28004 Madrid, Spain
Dig Dis Sci 54:1079-86. 2009..The RR of developing GERD was 2.8 (95% CI: 1.7-4.9) in the IBS cohort compared with the comparison cohort. A first diagnosis of either IBS or GERD significantly increases the risk of a subsequent diagnosis of the other condition...
Chest pain without established ischaemic heart disease in primary care patients: associated comorbidities and mortalityAna Ruigómez
Spanish Centre for Pharmacoepidemiologic Research CEIFE, Madrid, Spain
Br J Gen Pract 59:e78-86. 2009..The remainder have what is generally referred to as non-cardiac chest pain, which has been associated with gastrointestinal, neuromusculoskeletal, pulmonary, and psychiatric causes...
Gastroesophageal reflux disease in children and adolescents in primary careAna Ruigómez
Spanish Centre for Pharmacoepidemiological Research CEIFE, Madrid, Spain
Scand J Gastroenterol 45:139-46. 2010..To determine the prevalence and incidence of a diagnosis of gastroesophageal reflux disease (GERD) in children and adolescents in UK primary care, and to assess comorbidities that are associated with a diagnosis of GERD...
Validation of ischemic cerebrovascular diagnoses in the health improvement network (THIN)Ana Ruigómez
Centro Español de Investigación Farmacoepidemiológica CEIFE, Madrid, Spain
Pharmacoepidemiol Drug Saf 19:579-85. 2010..To evaluate the validity of recorded diagnoses of ischemic cerebrovascular events requiring hospitalization within The Health Improvement Network (THIN) UK primary care database...
Follow-up of a cohort of children and adolescents with gastro-esophageal reflux disease who were free of reflux esophagitis at initial diagnosisAna Ruigómez
Spanish Centre for Pharmacoepidemiologic Research CEIFE, Madrid, Spain
Scand J Gastroenterol 45:814-21. 2010..Here we aimed to describe the natural history of GERD in a pediatric population with no reflux esophagitis at initial diagnosis, assessing diagnoses of new esophageal complications and extra-esophageal conditions...
Treatment patterns in paediatric patients with a new diagnosis of gastroesophageal reflux diseaseAna Ruigómez
Spanish Centre for Pharmacoepidemiologic Research, CEIFE, Madrid, Spain
Eur J Gastroenterol Hepatol 23:232-7. 2011..Few data exist on the treatment of gastroesophageal reflux disease (GERD) in paediatrics. The objective of this study was to examine treatment patterns of GERD in paediatrics in the primary care...
Endoscopic findings in a cohort of newly diagnosed gastroesophageal reflux disease patients registered in a UK primary care databaseA Ruigomez
Centro Español de Investigación Farmacoepidemiológica CEIFE, Madrid, Spain
Dis Esophagus 20:504-9. 2007..Male gender, increasing age and a history of bleeding were risk factors for esophageal complications...
Comparison of gastro-oesophageal reflux disease and heartburn diagnoses in UK primary careAna Ruigómez
Centro Español de Investigación Farmacoepidemiológica CEIFE, Madrid, Spain
Curr Med Res Opin 22:1661-8. 2006..It is unclear how gastro-oesophageal reflux disease (GORD) is diagnosed in primary care. The aim of this study is to compare patients given a diagnosis of GORD with those diagnosed with heartburn...
Risk of mortality in a cohort of patients newly diagnosed with chronic atrial fibrillationAna Ruigómez
Centro Español de Investigación Farmacoepidemiológica, Spain
BMC Cardiovasc Disord 2:5. 2002..To evaluate the role of co-morbidity and other factors on the risk of dying among AF patients...
Chest pain in general practice: incidence, comorbidity and mortalityAna Ruigómez
Centro Español de Investigación Farmacoepidemiológica CEIFE, Madrid, Spain
Fam Pract 23:167-74. 2006..Chest pain is a common symptom that presents the primary care physician with a complex diagnostic and therapeutic challenge...
Predictors and prognosis of paroxysmal atrial fibrillation in general practice in the UKAna Ruigómez
Centro Español de Investigación Farmacoepidemiológica CEIFE, Madrid, Spain
BMC Cardiovasc Disord 5:20. 2005....
Gastroesophageal reflux disease and asthma: a longitudinal study in UK general practiceAna Ruigómez
Centro Español de Investigación Farmacoepidemiológica CEIFE, C Almirante 28, 2o, 28004 Madrid, Spain
Chest 128:85-93. 2005..The aim of our study was to investigate the temporal relationship between first diagnoses of GERD and asthma in general practice...
One-year follow-up of newly diagnosed irritable bowel syndrome patientsA Ruigomez
Centro Español de Investigación Farmacoepidemiológica CEIFE, Madrid, Spain
Aliment Pharmacol Ther 13:1097-102. 1999..Irritable bowel syndrome is the most common functional gastrointestinal disorder seen by general physicians...
Natural history of gastro-oesophageal reflux disease diagnosed in general practiceA Ruigomez
Centro Español de Investigación Farmacoepidemiológica CEIFE, Madrid, Spain
Aliment Pharmacol Ther 20:751-60. 2004..Cross-sectional studies indicate that gastro-oesophageal reflux disease symptoms have a prevalence of 10-20% in Western countries and are associated with obesity, smoking, oesophagitis, chest pain and respiratory disease...
Risk of irritable bowel syndrome after an episode of bacterial gastroenteritis in general practice: influence of comorbiditiesAna Ruigómez
Centro Español de Investigación Farmacoepidemiológica, Madrid, Spain
Clin Gastroenterol Hepatol 5:465-9. 2007....
Incidence of chronic atrial fibrillation in general practice and its treatment patternAna Ruigómez
Centro Español de Investigación Farmacoepidemiológica CEIFE, C Almirante 28, 2 degrees, 28004, Madrid, Spain
J Clin Epidemiol 55:358-63. 2002..Less than half of patients with chronic AF and no contraindications for anticoagulation received warfarin within the first trimester after the diagnosis...
Is hormone replacement therapy associated with an increased risk of irritable bowel syndrome?Ana Ruigómez
Centro Español de Investigación Farmacoepidemiológica CEIFE, Madrid, Spain
Maturitas 44:133-40. 2003..Hormonal status could be involved in the occurrence of irritable bowel syndrome (IBS). The authors examined the risk of developing IBS in women using hormone replacement therapy (HRT)...
Relationship between gastroesophageal reflux disease and COPD in UK primary careLuis A Garcia Rodriguez
Spanish Centre for Pharmacoepidemiological Research, CEIFE, Madrid, Spain
Chest 134:1223-30. 2008..The aim of this study was to investigate the relationship between diagnoses of COPD and gastroesophageal reflux disease (GERD) in primary care...
Prevalence, incidence, morbidity and treatment patterns in a cohort of patients diagnosed with anxiety in UK primary careElisa Martín-Merino
Centro Español de Investigación Farmacoepidemiológica, Almirante 28 no 2, Madrid, Spain
Fam Pract 27:9-16. 2010..Anxiety disorders are common and can cause substantial quality of life impairment...
Esophageal stricture: incidence, treatment patterns, and recurrence rateAna Ruigómez
Centro Español de Investigación Farmacoepidemiológica, Madrid, Spain
Am J Gastroenterol 101:2685-92. 2006..We aimed to determine the incidence, natural history, and recurrence rate of esophageal stricture diagnosed in primary care...
Acute gastroenteritis is followed by an increased risk of inflammatory bowel diseaseLuis Alberto García Rodríguez
Centro Español de Investigación Farmacoepidemiológica, Madrid, Spain
Gastroenterology 130:1588-94. 2006..We explored the relationship between infectious gastroenteritis and the occurrence of IBD using data from the General Practice Research Database...
Hospitalised ischaemic cerebrovascular accident and risk factors in a primary care databaseElisa Martín-Merino
Spanish Centre for Pharmacoepidemiologic Research CEIFE, Madrid, Spain
Pharmacoepidemiol Drug Saf 20:1050-6. 2011..Identification of risk factors can reduce its incidence. We aim to estimate the incidence rate (IR) of hospitalised ICVA in the general population by sex and quantify its risk associated with several factors...
Acid-suppressive drugs and community-acquired pneumoniaLuis Alberto Garcia Rodriguez
Spanish Centre for Pharmacoepidemiological Research CEIFE, Madrid, Spain
Epidemiology 20:800-6. 2009..Acid suppression may increase the risk of community-acquired pneumonia. We investigated this association in the United Kingdom primary care system taking account of the potential for confounding by indication...
Use of acid-suppressing drugs and the risk of bacterial gastroenteritisLuis Alberto García Rodríguez
Centro Español de Investigación Farmacoepidemiológica, Madrid, Spain
Clin Gastroenterol Hepatol 5:1418-23. 2007..Gastric acid is a defense mechanism against gastrointestinal infections caused by ingested bacteria. Studies have suggested that the use of acid-suppressing drugs may increase the risk of gastroenteritis (GE)...
Study of a cohort of patients newly diagnosed with depression in general practice: prevalence, incidence, comorbidity, and treatment patternsElisa Martín-Merino
Centro Español de Investigación Farmacoepidemiológica, Madrid, Spain AstraZeneca R and D, Molndal, and Section of Preventive Cardiology, Gothenburg University, Sweden and Department of Public Health and Caring Science, Uppsala University, Sweden
Prim Care Companion J Clin Psychiatry 12:PCC.08m00764. 2010....
Rheumatoid arthritis in UK primary care: incidence and prior morbidityL A García Rodríguez
Spanish Centre for Pharmacoepidemiological Research CEIFE, Madrid, Spain
Scand J Rheumatol 38:173-7. 2009..To estimate the incidence of rheumatoid arthritis (RA) in primary care and to investigate associations with consultation behaviour, risk factors, and comorbidities, using the UK General Practice Research Database (GPRD)...
Presence of diabetes related complication at the time of NIDDM diagnosis: an important prognostic factorA Ruigomez
CEIFE, Spanish Centre for Pharmacoepidemiologic Research, Madrid
Eur J Epidemiol 14:439-45. 1998....
[Incidence rate of community acquired pneumonia in a population cohort registered in BIFAP]Ana Chacón García
Medicina Preventiva y Gestión de Calidad, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Aten Primaria 42:543-9. 2010..To estimate the incidence rate (IR) of community acquired pneumonia (CAP) using the information in the Primary Healthcare database in Spain...
Depression and treatment with antidepressants are associated with the development of gastro-oesophageal reflux diseaseE Martín-Merino
Spanish Centre for Pharmacoepidemiologic Research, Madrid, Spain
Aliment Pharmacol Ther 31:1132-40. 2010..The roles of depression and antidepressants in triggering reflux symptoms remain unclear...
Gender and drug treatment as determinants of mortality in a cohort of heart failure patientsA Ruigomez
Centro Español de Investigación Farmacoepidemiológica, Madrid, Spain
Eur J Epidemiol 17:329-35. 2001..We assessed gender differences in the risk of mortality in heart failure (HF) patients and evaluated the association between HF drug treatment and mortality...
