Research Topics
Species | Emilio RosSummaryCountry: Spain Publications
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Publications
Influence of HDL cholesterol on preclinical carotid atherosclerosis in familial hypercholesterolemiaMireia Junyent
Servei d'Endocrinologia i Nutrici, , , Barcelona, Spain
Arterioscler Thromb Vasc Biol 26:1107-13. 2006..Because the HDL cholesterol level and the total cholesterol/HDL ratio are strong predictors of preclinical carotid atherosclerosis, HDL cholesterol-raising strategies should have an important therapeutic role in FH...
Atorvastatin versus Bezafibrate in Mixed Hyperlipidaemia : Randomised Clinical Trial of Efficacy and Safety (the ATOMIX Study)Emilio Ros
Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic i Provincial, Barcelona, Spain
Clin Drug Investig 23:153-65. 2003....- Fatty acid composition of nuts--implications for cardiovascular healthEmilio Ros
Unitat de Lípids, Sevei d Endocrinologia i Nutrició, Institut d Investigacions Biomèdiques August Pi Sunyer, Hospital Clinic, Barcelona, Spain
Br J Nutr 96:S29-35. 2006.... 
Health benefits of nut consumptionEmilio Ros
Lipid Clinic, Endocrinology and Nutrition Service, Institutd Investigacions Biomèdiques August Pii Sunyer, Hospital Clinic, Barcelona and Ciber Fisiopatología de la Obesidady Nutrición CIBERobn, Instituto de Salud Carlos III ISCIII, Spain
Nutrients 2:652-82. 2010..In conclusion, nuts are nutrient rich foods with wide-ranging cardiovascular and metabolic benefits, which can be readily incorporated into healthy diets...- Nuts and novel biomarkers of cardiovascular diseaseEmilio Ros
Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomèdiques August Pi Sunyer, Hospital Clinic, Barcelona and Ciber Fisiopatología de la Obesidad y Nutrición, Barcelona, Spain
Am J Clin Nutr 89:1649S-56S. 2009..Although more studies are warranted, the emerging picture is that nut consumption beneficially influences cardiovascular risk beyond cholesterol lowering... - A walnut diet improves endothelial function in hypercholesterolemic subjects: a randomized crossover trialEmilio Ros
Lipid Clinic at the Endocrinology and Nutrition Service, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
Circulation 109:1609-14. 2004..Endothelial dysfunction is associated with CAD and its risk factors and is reversed by antioxidants and marine n-3 fatty acids. Walnuts are a rich source of both antioxidants and alpha-linolenic acid, a plant n-3 fatty acid... - Nuts and berries for heart healthEmilio Ros
Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, 08036, Barcelona, Spain
Curr Atheroscler Rep 12:397-406. 2010..Berries are another plant food rich in bioactive phytochemicals, particularly flavonoids, for which there is increasing evidence of benefits on cardiometabolic risk that are linked to their potent antioxidant power... - Fatty acids in serum phospholipids and carotid intima-media thickness in Spanish subjects with primary dyslipidemiaAleix Sala-Vila
Unitat de Lípids, Sunyer Hospital Clínic, Barcelona, Spain
Am J Clin Nutr 92:186-93. 2010..High consumption of unsaturated fatty acid-rich foods, such as olive oil, nuts, and seafood, might underlie this paradox... - Acute effects of high-fat meals enriched with walnuts or olive oil on postprandial endothelial functionBerenice Cortés
Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain
J Am Coll Cardiol 48:1666-71. 2006.... - Inhibition of circulating immune cell activation: a molecular antiinflammatory effect of the Mediterranean dietMari Pau Mena
Department of Internal Medicine, Institut d Investigacions Biomediques August Pi i Sunyer, Instituto de Salud Carlos III, Spain
Am J Clin Nutr 89:248-56. 2009..Adherence to the Mediterranean diet (Med-Diet) is associated with a reduced risk of cardiovascular disease (CVD). However, the molecular mechanisms involved are not fully understood... - Serum sterol responses to increasing plant sterol intake from natural foods in the Mediterranean dietVeronica Escurriol
Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomèdiques Ausgust Pi Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
Eur J Nutr 48:373-82. 2009..Phytosterols in natural foods are thought to inhibit cholesterol absorption. The Mediterranean diet is rich in phytosterol-containing plant foods... - Impact of low-density lipoprotein receptor mutational class on carotid atherosclerosis in patients with familial hypercholesterolemiaMireia Junyent
Unitat de Lípids, Servei d Endocrinologia, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Villarroel 160, 08036 Barcelona, Spain
Atherosclerosis 208:437-41. 2010..The effect of different LDLR mutations on coronary heart disease (CHD) risk is insufficiently defined. We assessed carotid intima-media thickness (IMT), a surrogate marker of CHD, in relation to LDLR mutational class in FH... - Carotid atherosclerosis and vascular age in the assessment of coronary heart disease risk beyond the Framingham Risk ScoreMireia Junyent
Unitat de Lípids, Servei d Endocrinologia i Nutrició, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
Atherosclerosis 196:803-9. 2008..To assess how ultrasound measurements of carotid intima-media thickness (CIMT) and plaque burden compare with the Framingham Risk Score (FRS) in a clinical setting... - Effect of Mediterranean diet on the expression of pro-atherogenic genes in a population at high cardiovascular riskVicenta Llorente-Cortes
Cardiovascular Research Center, CSIC ICCC, Hospital Sant Pau, Barcelona, Spain
Atherosclerosis 208:442-50. 2010..Dietary intervention can thus actively modulate the expression of pro-atherothrombotic genes even in a high-risk population... - Carotid atherosclerosis in familial combined hyperlipidemia associated with the APOB/APOA-I ratioMireia Junyent
Unitat de Lípids, Servei d Endocrinologia i Nutrició, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
Atherosclerosis 197:740-6. 2008..We assessed carotid intima-media thickness (IMT) and plaque in relation to classical risk factors and apolipoprotein A-I (apoA-I) and B (apoB) levels in patients with FCHL... - Carotid and femoral plaque burden is inversely associated with the α-linolenic acid proportion of serum phospholipids in Spanish subjects with primary dyslipidemiaAleix Sala-Vila
Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
Atherosclerosis 214:209-14. 2011.... - Polyphenol-rich foods in the Mediterranean diet are associated with better cognitive function in elderly subjects at high cardiovascular riskCinta Valls-Pedret
Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
J Alzheimers Dis 29:773-82. 2012..The results reinforce the notion that Mediterranean diet components might counteract age-related cognitive decline... - Effects of plant sterol esters in skimmed milk and vegetable-fat-enriched milk on serum lipids and non-cholesterol sterols in hypercholesterolaemic subjects: a randomised, placebo-controlled, crossover studyPatricia Casas-Agustench
Lipid Clinic, Service of Endocrinology and Nutrition, Institut d Investigations Biomediques August Pi Sunyer, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
Br J Nutr 107:1766-75. 2012..Basal and post-treatment changes in markers of cholesterol metabolism indicating low cholesterol synthesis and high cholesterol absorption predicted improved LDL-C responses to PS... - Femoral atherosclerosis in heterozygous familial hypercholesterolemia: influence of the genetic defectMireia Junyent
Unitat de Lípids, Servei d Endocrinologia i Nutrició, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
Arterioscler Thromb Vasc Biol 28:580-6. 2008.... - Effect of a traditional Mediterranean diet on lipoprotein oxidation: a randomized controlled trialMontserrat Fito
Lipids and Cardiovascular Epidemiology Unit, Institut Municipal d Investigacio Medica, IMIM Hospital del Mar, Barcelona, Spain
Arch Intern Med 167:1195-203. 2007..Despite the richness in antioxidants of the Mediterranean diet, to our knowledge, no randomized controlled trials have assessed its effect on in vivo lipoprotein oxidation... - Effects of red wine polyphenols and alcohol on glucose metabolism and the lipid profile: a randomized clinical trialGemma Chiva-Blanch
Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
Clin Nutr 32:200-6. 2013..The aim of the present study was to compare the effects of moderate consumption of red wine, dealcoholized red wine, and gin on glucose metabolism and the lipid profile... - Determinants of the omega-3 index in a Mediterranean population at increased risk for CHDAleix Sala-Vila
Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomèdiques August Pi Sunyer, Unitat de Lípids, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
Br J Nutr 106:425-31. 2011..Nevertheless, the high omega-3 index could at least partially explain the paradox of low rates of fatal CHD in Spain despite a high background prevalence of cardiovascular risk factors... - Plant sterol intake and education level in the Spanish EPIC cohortVeronica Escurriol
Lipid Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, CIBEROBN, Instituto de Salud Carlos III, Barcelona, Spain
Nutrition 25:769-73. 2009.... - Phytosterol plasma concentrations and coronary heart disease in the prospective Spanish EPIC cohortVeronica Escurriol
Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
J Lipid Res 51:618-24. 2010..The data suggest that plasma sitosterol levels are associated with a lower CHD risk while being markers of a lower cardiometabolic risk in the EPIC-Spain cohort, a population with a high phytosterol intake... - Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trialRamon Estruch
Institut d Investigacions Biomèdiques August Pi Sunyer, Municipal Institut for Medical Research, University of Barcelona, and Catalan Institute of Health, Barcelona, Spain
Ann Intern Med 145:1-11. 2006..The Mediterranean diet has been shown to have beneficial effects on cardiovascular risk factors... - Down-regulation of adhesion molecules and other inflammatory biomarkers after moderate wine consumption in healthy women: a randomized trialEmilio Sacanella
Department of Internal Medicine, Hospital Clinic, Hospital Clinic, University of Barcelona, Barcelona, Spain
Am J Clin Nutr 86:1463-9. 2007..The mechanism for this beneficial effect might be reduced inflammatory responses, as suggested by prospective studies and small clinical trials in men. No studies have evaluated the antiinflammatory effects of wine in women... - Fibrates modify the expression of key factors involved in bile-acid synthesis and biliary-lipid secretion in gallstone patientsNuria Roglans
Pharmacology Unit, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
Eur J Clin Pharmacol 59:855-61. 2004.... - Dealcoholized red wine decreases systolic and diastolic blood pressure and increases plasma nitric oxide: short communicationGemma Chiva-Blanch
Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
Circ Res 111:1065-8. 2012..Experimental studies have shown a potential blood pressure (BP) lowering effect of red wine polyphenols, whereas the effects of ethanol and polyphenols on BP in humans are not yet clear... - Cross-sectional assessment of nut consumption and obesity, metabolic syndrome and other cardiometabolic risk factors: the PREDIMED studyNúria Ibarrola-Jurado
Human Nutrition Unit, Hospital Universitari de Sant Joan de Reus, Institut d Investigació Sanitària Pere Virgili IISPV, Universitat Rovira i Virgili, Reus, Spain
PLoS ONE 8:e57367. 2013..Limited data are available on the epidemiological associations between nut intake and cardiometabolic risk factors... - The use of Achilles tendon sonography to distinguish familial hypercholesterolemia from other genetic dyslipidemiasMireia Junyent
, Servei d'Endocrinologia i Nutrici, , , Barcelona, Spain
Arterioscler Thromb Vasc Biol 25:2203-8. 2005..CONCLUSIONS: Sonographic AT characteristics are normal in non-FH dyslipidemias. Identification of suspected FH by ultrasound using sex- and age-specific AT thickness thresholds is recommended... - Nonalcoholic fatty liver disease is associated with carotid atherosclerosis: a case-control studyAngel Brea
Lipid Clinic, Internal Medicine Service, Hospital San Millán San Pedro, Logrono, Spain
Arterioscler Thromb Vasc Biol 25:1045-50. 2005..Nonalcoholic fatty liver disease (NAFLD) frequently coexists with obesity, diabetes, and dyslipidemia. We examined whether NAFLD was associated with atherosclerosis, as measured by ultrasound in the carotid arteries... - [Carotid ultrasound in the assessment of preclinical atherosclerosis. Distribution of intima-media thickness values and plaque frequency in a Spanish community cohort]Mireia Junyent
, , , , Barcelona,
Med Clin (Barc) 125:770-4. 2005..Carotid IMT values in a Spanish community cohort were lower than those reported for countries with higher cardiovascular risk, such as Northern European countries and the US... - Biomarker assessment of the immunomodulator effect of atorvastatin in stable renal transplant recipients and hypercholesterolemic patientsDavid Guillen
Pharmacology Laboratory Biomedical Diagnosis Center, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
Mol Diagn Ther 14:357-66. 2010..However, the role of statins in the immunosuppressive response that is achieved in individual patients remains to be assessed... - [Hypertriglyceridemic acute pancreatitis. Is its clinical course different from lithiasic acute pancreatitis?]Salvador Navarro
Servicio de Gastroenterologia, Institut de Malalties Digestives, Hospital Clinic de Barcelona, Barcelona, Spain
Med Clin (Barc) 123:567-70. 2004..The objective was to analyze the clinical performance of hypertriglyceridemic acute pancreatitis and the diagnosis value of the serum measurement of pancreatic enzymes... - Dietary cis-monounsaturated fatty acids and metabolic control in type 2 diabetesEmilio Ros
Lipid Clinic, Nutrition and Dietetics Service, Institut d Investigacions Biomédiques August Pi Sunyer IDIBAPS, Hospital Clinico, University of Barcelona, Barcelona, Spain
Am J Clin Nutr 78:617S-625S. 2003..Thus, there is good scientific support for MUFA diets as an alternative to low-fat diets for medical nutrition therapy in diabetes... - Preclinical vascular disease in systemic lupus erythematosus and primary antiphospholipid syndromeSonia Jimenez
Servicio de Enfermedades Autoinmunes, ICMiD, Hospital Clinic, C Villaroel 170, 08036 Barcelona, Spain
Rheumatology (Oxford) 44:756-61. 2005..To determine the prevalence of preclinical vascular disease and associated risk factors in patients with systemic lupus erythematosus (SLE) or primary antiphospholipid syndrome (APS)... - Other relevant components of nuts: phytosterols, folate and mineralsRamon Segura
Department of Physiological Sciences II, Faculty of Medicine, IDIBELL, University of Barcelona, Barcelona, Spain
Br J Nutr 96:S36-44. 2006.... - Utility of ambulatory 24-hour esophageal pH and motility monitoring in noncardiac chest pain: report of 90 patients and review of the literatureGloria Lacima
Digestive Motility Unit, Institut de Malalties Digestives, Hospital Clinic, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain
Dig Dis Sci 48:952-61. 2003..Causes of chest pain other than high esophageal pressures and acid reflux must still be sought in most patients with chest pain of unknown origin after a negative cardiac work-up... - Reductions in plasma cholesterol levels after fenofibrate treatment are negatively correlated with resistin expression in human adipose tissueMireia Jové
Pharmacology Unit, Faculty of Pharmacy and the Surgical Department and Lipid Clinic, Nutrition and Dietetics Service, Hospital Clinic i Provincial, University of Barcelona, Barcelona, Spain
Metabolism 52:351-5. 2003..53, P =.039, n = 8), but not with triglyceride levels (r2 =.02, P =.73, n = 8). These results suggest that cholesterol regulates resistin expression in human white adipose tissue... - Effect of atorvastatin and bezafibrate on plasma levels of C-reactive protein in combined (mixed) hyperlipidemiaJuan A Gómez-Gerique
Biochemistry Service, Fundacion Jimenez Diaz, Avda Reyes Catolicos, 2, 28040, Madrid, Spain
Atherosclerosis 162:245-51. 2002..82, P=0.023). These results suggest a potential anti-atherosclerotic additional benefit of atorvastatin in patients at a risk of cardiovascular disease... - A large randomized individual and group intervention conducted by registered dietitians increased adherence to Mediterranean-type diets: the PREDIMED studyItziar Zazpe
Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain
J Am Diet Assoc 108:1134-44; discussion 1145. 2008..To assess the effectiveness of an intervention aimed to increase adherence to a Mediterranean diet... - Fibrate treatment does not modify the expression of acyl coenzyme A oxidase in human liverNuria Roglans
Pharmacology Unit, Faculty of Pharmacy, University of Barcelona, Surgical Department and Lipid Clinic, Nutrition and Dietetics Service, Hospital Clinic i Provincial, Spain
Clin Pharmacol Ther 72:692-701. 2002..There is no conclusive evidence that humans are unresponsive to peroxisome proliferation, and concern exists about the long-term safety of fibrate treatment... - Effects of milk supplementation with conjugated linoleic acid (isomers cis-9, trans-11 and trans-10, cis-12) on body composition and metabolic syndrome componentsNuria Laso
Dep Farmacología y Química Terapéutica, Universidad de Barcelona, IDIBAPS, Casanova 143, E 08036 Barcelona, Spain
Br J Nutr 98:860-7. 2007..The supplementation of milk with 3 g CLA over 12 weeks results in a significant reduction of fat mass in overweight but not in obese subjects. CLA supplementation was not associated with any adverse effects or biological changes... - The apolipoprotein B R3500Q gene mutation in Spanish subjects with a clinical diagnosis of familial hypercholesterolemiaSergio Castillo
Departamento de Bioqui mica y Biologi a Molecular y Celular, Facultad de Ciencias, Universidad de Zaragoza, Plaza San Francisco s n, 51008, Zaragoza, Spain
Atherosclerosis 165:127-35. 2002..In conclusion, the R3500Q mutation of the apolipoprotein B gene, a common cause of FH in central Europe, is infrequent in the general Spanish population, but it is common in Galicia... - Tendon xanthomas in familial hypercholesterolemia are associated with cardiovascular risk independently of the low-density lipoprotein receptor gene mutationFernando Civeira
Laboratorio de Investigacion Molecular, Hospital Universitario Miguel Servet, Instituto Aragones de Ciencias de la Salud, Zaragoza, Spain
Arterioscler Thromb Vasc Biol 25:1960-5. 2005..To investigate the significance of tendon xanthomas (TX) in heterozygous subjects with familial hypercholesterolemia (hFH)... - Nuts: nutrition and health outcomes. PrefaceJoan Sabate
Br J Nutr 96:S1-2. 2006 - Modulation of the atrial specific Kv1.5 channel by the n-3 polyunsaturated fatty acid, alpha-linolenic acidMiriam Guizy
Instituto de Farmacologia y Toxicologia CSIC UCM, 28040 Madrid, Spain
J Mol Cell Cardiol 44:323-35. 2008..Together, these effects suggest that the antiarrhythmic potential of diets enriched with plant-derived n-3 PUFA result, in part, from direct effects on cardiac ion channels... - Treatment of type IIb familial combined hyperlipidemia with the combination pravastatin-piperazine sultosilateLluis Masana
School of Medicine, Rovira i Virgili University, Reus, Spain
Eur J Pharmacol 496:205-12. 2004.... - The role of tree nuts and peanuts in the prevention of coronary heart disease: multiple potential mechanismsPenny M Kris-Etherton
Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA
J Nutr 138:1746S-1751S. 2008..Nuts and peanuts are food sources that are a composite of numerous cardioprotective nutrients and if routinely incorporated in a healthy diet, population risk of CHD would therefore be expected to decrease markedly... - Dietary fibre, nuts and cardiovascular diseasesJordi Salas-Salvado
Unitat de Nutricio Humana, Facultat de Medicina i Ciencies de la Salut de Reus, Universitat Rovira i Virgili, Reus, Spain
Br J Nutr 96:S46-51. 2006..After cereals, nuts are the vegetable foods that are richest in fibre, which may partly explain their benefit on the lipid profile and cardiovascular health...