Antonio Rodriguez

Summary

Country: Spain

Publications

  1. pmc A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants
    Antonio Rodriguez
    Department of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain
    Mol Cell 33:616-26. 2009
  2. pmc The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators
    Sara Martínez-Martínez
    Department of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, 28029 Madrid, Spain
    Proc Natl Acad Sci U S A 106:6117-22. 2009
  3. pmc IL10 released by a new inflammation-regulated lentiviral system efficiently attenuates zymosan-induced arthritis
    Guillermo Garaulet
    Department of Molecular Biology, Universidad Autonoma de Madrid, Madrid, Spain
    Mol Ther 21:119-30. 2013
  4. ncbi request reprint ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1
    Ana Urzainqui
    Servicio de Inmunologia, Hospital de la Princesa, Universidad Autonoma de Madrid, Madrid, Spain
    Immunity 17:401-12. 2002
  5. doi request reprint NFATc3 regulates the transcription of genes involved in T-cell activation and angiogenesis
    Katia Urso
    Department of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain
    Blood 118:795-803. 2011

Collaborators

  • Susana De La Luna
  • Francisco Sanchez-Madrid
  • M S Cyert
  • Sara Martínez-Martínez
  • Guillermo Garaulet
  • Amelia Escolano
  • Arántzazu Alfranca
  • Katia Urso
  • Juan Miguel Redondo
  • Ana Urzainqui
  • Juan M Redondo
  • Raquel López-Fontal
  • Sonsoles Hortelano
  • María Torrente
  • Inmaculada Ortega
  • Alicia Raya
  • Felipe Were
  • María Dolores López-Maderuelo
  • Eulàlia Salichs
  • Lali Genescà
  • Alfonso Luque
  • Marcel Deckert
  • Fernando Viedma
  • Maria Yanez-Mo
  • Juan M Serrador
  • Angel L Corbi
  • Jesus Vazquez
  • Jose L Alonso-Lebrero

Detail Information

Publications5

  1. pmc A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants
    Antonio Rodriguez
    Department of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain
    Mol Cell 33:616-26. 2009
    ..These studies suggest that LxVP-type sites are a common feature of calcineurin substrates, and that immunosuppressant-immunophilin complexes inhibit calcineurin by interfering with this mode of substrate recognition...
  2. pmc The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators
    Sara Martínez-Martínez
    Department of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, 28029 Madrid, Spain
    Proc Natl Acad Sci U S A 106:6117-22. 2009
    ..Thus, competition by substrates and modulators for a common docking site appears to be an essential mechanism in the regulation of Ca(2+)-calcineurin signaling...
  3. pmc IL10 released by a new inflammation-regulated lentiviral system efficiently attenuates zymosan-induced arthritis
    Guillermo Garaulet
    Department of Molecular Biology, Universidad Autonoma de Madrid, Madrid, Spain
    Mol Ther 21:119-30. 2013
    ..This inflammation-regulated expression system has potential application in the design of new strategies for the local treatment of chronic inflammatory diseases such as cardiovascular and autoimmune diseases...
  4. ncbi request reprint ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1
    Ana Urzainqui
    Servicio de Inmunologia, Hospital de la Princesa, Universidad Autonoma de Madrid, Madrid, Spain
    Immunity 17:401-12. 2002
    ..These data unveil a new functional role for the ERMs (ezrin/radixin/moesin) as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases and show that PSGL-1 is a signaling molecule in leukocytes...
  5. doi request reprint NFATc3 regulates the transcription of genes involved in T-cell activation and angiogenesis
    Katia Urso
    Department of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain
    Blood 118:795-803. 2011
    ..These effects, observed on short-term suppression by mRNA knock-down, are likely to have been masked by compensatory effects in gene-knockout studies...