Antonio Rodriguez

Summary

Country: Spain

Publications

  1. ncbi A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants
    Antonio Rodriguez
    Department of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain
    Mol Cell 33:616-26. 2009
  2. ncbi The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators
    Sara Martínez-Martínez
    Department of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, 28029 Madrid, Spain
    Proc Natl Acad Sci U S A 106:6117-22. 2009
  3. ncbi IL10 released by a new inflammation-regulated lentiviral system efficiently attenuates zymosan-induced arthritis
    Guillermo Garaulet
    Department of Molecular Biology, Universidad Autonoma de Madrid, Madrid, Spain
    Mol Ther 21:119-30. 2013
  4. ncbi ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1
    Ana Urzainqui
    Servicio de Inmunologia, Hospital de la Princesa, Universidad Autonoma de Madrid, Madrid, Spain
    Immunity 17:401-12. 2002
  5. ncbi NFATc3 regulates the transcription of genes involved in T-cell activation and angiogenesis
    Katia Urso
    Department of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain
    Blood 118:795-803. 2011

Collaborators

  • Susana De La Luna
  • Francisco Sanchez-Madrid
  • M S Cyert
  • Sara Martínez-Martínez
  • Guillermo Garaulet
  • Arántzazu Alfranca
  • Amelia Escolano
  • Katia Urso
  • Juan Miguel Redondo
  • Ana Urzainqui
  • Sonsoles Hortelano
  • Juan M Redondo
  • María Torrente
  • Raquel López-Fontal
  • Inmaculada Ortega
  • Alicia Raya
  • Felipe Were
  • Eulàlia Salichs
  • María Dolores López-Maderuelo
  • Lali Genescà
  • Maria Yanez-Mo
  • Alfonso Luque
  • Jesus Vazquez
  • Jose L Alonso-Lebrero
  • Angel L Corbi
  • Fernando Viedma
  • Marcel Deckert
  • Juan M Serrador

Detail Information

Publications5

  1. ncbi A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants
    Antonio Rodriguez
    Department of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain
    Mol Cell 33:616-26. 2009
    ..These studies suggest that LxVP-type sites are a common feature of calcineurin substrates, and that immunosuppressant-immunophilin complexes inhibit calcineurin by interfering with this mode of substrate recognition...
  2. ncbi The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators
    Sara Martínez-Martínez
    Department of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, 28029 Madrid, Spain
    Proc Natl Acad Sci U S A 106:6117-22. 2009
    ..Thus, competition by substrates and modulators for a common docking site appears to be an essential mechanism in the regulation of Ca(2+)-calcineurin signaling...
  3. ncbi IL10 released by a new inflammation-regulated lentiviral system efficiently attenuates zymosan-induced arthritis
    Guillermo Garaulet
    Department of Molecular Biology, Universidad Autonoma de Madrid, Madrid, Spain
    Mol Ther 21:119-30. 2013
    ..This inflammation-regulated expression system has potential application in the design of new strategies for the local treatment of chronic inflammatory diseases such as cardiovascular and autoimmune diseases...
  4. ncbi ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1
    Ana Urzainqui
    Servicio de Inmunologia, Hospital de la Princesa, Universidad Autonoma de Madrid, Madrid, Spain
    Immunity 17:401-12. 2002
    ..These data unveil a new functional role for the ERMs (ezrin/radixin/moesin) as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases and show that PSGL-1 is a signaling molecule in leukocytes...
  5. ncbi NFATc3 regulates the transcription of genes involved in T-cell activation and angiogenesis
    Katia Urso
    Department of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain
    Blood 118:795-803. 2011
    ..These effects, observed on short-term suppression by mRNA knock-down, are likely to have been masked by compensatory effects in gene-knockout studies...