Research Topics
Species | R Rodriguez-RoisinSummaryCountry: Spain Publications
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Publications
The airway pathophysiology of COPD: implications for treatmentRoberto Rodriguez-Roisin
Servei de Pneumologia, Institut d lnvestigacions Biomèdiques August Pi i Sunyer IDIBAPS, Hospital Clinic, Universitat de Barcelona, Villaroel, 170, 08036 Barcelona, Spain
COPD 2:253-62. 2005....
The GOLD initiative 2011: a change of paradigm?Roberto Rodriguez-Roisin
Servei de Pneumologia, Institut del Tòrax, Hospital Clinic, Universitat de Barcelona, IDIBAPS and CIBERES, Barcelona, Spain
Arch Bronconeumol 48:286-9. 2012..This revision debates not only the most significant aspects, which remain relatively intact, but also, and in particular, those that have been substantially modified compared with the GOLD revision from 2006...
Effects of cigarette smoke on endothelial function of pulmonary arteries in the guinea pigElisabet Ferrer
Department of Pulmonary Medicine, Hospital Clinic IDIBAPS, Barcelona, Spain
Respir Res 10:76. 2009..The objectives of this study were to evaluate the effects of long-term exposure to cigarette smoke on endothelial function and smooth muscle-cell proliferation in pulmonary arteries of guinea pigs...
Highlights of the ERS Task Force on pulmonary-hepatic vascular disorders (PHD)R Rodríquez-Roisin
Universitat de Barcelona Servei de Pneumologia, IDIBAPS, Hospital Clinic, Spain
J Hepatol 42:924-7. 2005
Mechanisms of hypoxemiaRobert Rodriguez-Roisin
Servei de Pneumologia, Hospital Clinic, Institut d Investigaciones Biomédiques Ausgust Pi i Sunyer, Universitat de Barcelona, Villarroel 170, 08036, Barcelona, Spain
Intensive Care Med 31:1017-9. 2005
COPD exacerbations.5: managementR Rodriguez-Roisin
Servei de Pneumologia, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
Thorax 61:535-44. 2006..A review of the most relevant evidence based therapeutic options currently available for the management of exacerbations of COPD...
Hepatopulmonary syndrome--a liver-induced lung vascular disorderRoberto Rodriguez-Roisin
Servei de Pneumologia Institut del Tòrax, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, CIBER Enfermedades Respiratorias, and the University of Barcelona, Barcelona, Spain
N Engl J Med 358:2378-87. 2008
Chronic obstructive pulmonary disease with lung cancer and/or cardiovascular diseaseRoberto Rodriguez-Roisin
Servei de Pneumologia, Hospital Clinic, Villarroel, 170, 08036 Barcelona, Spain
Proc Am Thorac Soc 5:842-7. 2008....
Ventilation-perfusion imbalance and chronic obstructive pulmonary disease staging severityRoberto Rodriguez-Roisin
Servei de Pneumologia, Hospital Clinic, Villarroel, 170 08036 Barcelona, Spain
J Appl Physiol 106:1902-8. 2009....
Pulmonary-Hepatic vascular Disorders (PHD)R Rodriguez-Roisin
Servei de Pneumologia, Hospital Clinic, Institut d Investigacions Biomèdiques August Pi Sunyer, Universitat de Barcelona, 08036 Barcelona, Spain
Eur Respir J 24:861-80. 2004
Effect of nitric oxide inhalation on respiratory system resistance in chronic obstructive pulmonary diseaseN Roger
Department de Medicina, Facultat de Medicina, Universitat de Barcelona, Spain
Eur Respir J 9:190-5. 1996..86 +/- 0.31%). From these results, we conclude that inhaled nitric oxide, at a concentration of 40 ppm, exerts no effect on respiratory system resistance in patients with chronic obstructive pulmonary disease or in healthy subjects...
Pulmonary gas exchange responses to histamine and methacholine challenges in mild asthmaA L Echazarreta
Dept de Medicina, , , Universitat de Barcelona, Spain
Eur Respir J 17:609-14. 2001....
Reduced expression of endothelial nitric oxide synthase in pulmonary arteries of smokersJ A Barbera
Department of Pulmonary Medicine, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
Am J Respir Crit Care Med 164:709-13. 2001..The diminished synthesis of nitric oxide may contribute to the alterations in the structure and endothelial function of pulmonary vessels in cigarette-smoke-induced respiratory disease...
Adenosine 5'-monophosphate in asthma: gas exchange and sputum cellular responsesH A Manrique
Servei de Pneumologia Institut del Tòrax, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, CIBER Enfermedades Respiratorias, Universitat de Barcelona, Barcelona, Spain
Eur Respir J 31:1205-12. 2008..The fully inhibited adenosine 5'-monophosphate-induced neutrophilia with residual hypoxaemia observed after salbutamol treatment is probably related to beta(2)-agonists acting on both bronchial and pulmonary circulation...
Mechanisms of worsening gas exchange during acute exacerbations of chronic obstructive pulmonary diseaseJ A Barbera
Departament de Medicina, Hospital Clinic, Universitat de Barcelona, Spain
Eur Respir J 10:1285-91. 1997....
Hepatopulmonary syndrome in candidates for liver transplantationG P Martínez
Servei de Anestesiologia i Reanimació, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Universitat de Barcelona, Spain
J Hepatol 34:651-7. 2001..We determined the incidence and the clinical and pulmonary functional characteristics of HPS in candidates for orthotopic liver transplantation (OLT) and tested their predicted accuracy...
Response to hypoxia of pulmonary arteries in chronic obstructive pulmonary disease: an in vitro studyV I Peinado
Dept of Pulmonary Medicine, , Hospital Clinic, Universitat de Barcelona, Spain
Eur Respir J 20:332-8. 2002..The depressed response of pulmonary arteries to hypoxia may contribute to abnormal gas exchange in chronic obstructive pulmonary disease...
Gas exchange and pulmonary hemodynamics during lung resection in patients at increased risk: relationship with preoperative exercise testingJ Ribas
, , Universitat de Barcelona, Barcelona, Spain
Chest 120:852-9. 2001..Preoperative measurement of PaO(2) during exercise and the distribution of perfusion by lung scan might be useful to identify those patients who are at the greatest risk of abnormal gas exchange during lung resections...
Pulmonary gas exchange and sputum cellular responses to inhaled leukotriene D(4) in asthmaA L Echazarreta
, Departament de Medicina, , , Universitat de Barcelona, Villaroel 170, 08036-Barcelona, Spain
Am J Respir Crit Care Med 164:202-6. 2001..These findings support the evidence that CysLTs, in addition to being potent bronchoconstrictors, also provoke profound disturbances of pulmonary gas exchange in asthma...
Mechanisms of pulmonary gas exchange improvement during a protective ventilatory strategy in acute respiratory distress syndromeM Mancini
Servei de Pneumologia (ICPCT, , , , Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Am J Respir Crit Care Med 164:1448-53. 2001..04). We conclude that the decrease in intrapulmonary shunt owing to alveolar recruitment remains the pivotal mechanism to explain improvement of arterial oxygenation during this PVS...
Home hospitalisation of exacerbated chronic obstructive pulmonary disease patientsC Hernandez
Servei de Pneumologia (ICPCT, Hospital Clinic, IDIBAPS, Barcelona, Spain
Eur Respir J 21:58-67. 2003..A comprehensive home care intervention in selected chronic obstructive pulmonary disease exacerbations appears as cost effective. The home hospitalisation intervention generates better outcomes at lower costs than conventional care...
Association study of proposed candidate genes/regions in a population of Spanish asthmaticsJ B Soriano
Departament d Epidemiologia i Salut Pública, Institut Municipal d Investigacio Medica, Barcelona, Spain
Eur J Epidemiol 16:745-50. 2000..No association could be observed in this sample of Spanish asthmatics with the genes/regions studied...
Toward a consensus definition for COPD exacerbationsR Rodriguez-Roisin
Department of Medicine, University of Barcelona, Barcelona, Spain
Chest 117:398S-401S. 2000....
Is it necessary to treat all patients with idiopathic pulmonary fibrosis?A Xaubet
Servei de Pneumologia i Al lèrgia Respiratoria, Institut Clinic de Pneumologia i Cirurgia Toracica, Hospital Clinic, Universitat de Barcelona, Spain
Sarcoidosis Vasc Diffuse Lung Dis 18:289-95. 2001..To investigate the clinical course of untreated patients with idiopathic pulmonary fibrosis (usual interstitial pneumonia) (IPF/UIP)...
Fluticasone propionate attenuates platelet-activating factor-induced gas exchange defects in mild asthmaA A Acuña
Servei de Pneumologia i Allergia Respiratoria, Institut Clinic de Pneumologia i Cirurgia Toracica, Hospital Clinic, Villarroel, Barcelona, Spain
Eur Respir J 19:872-8. 2002....
Mitochondrial dysfunction in COPD patients with low body mass indexR A Rabinovich
Pneumology Service ICT, Hospital Clinic, Barcelona University, Spain
Eur Respir J 29:643-50. 2007..In conclusion, chronic obstructive pulmonary disease patients with low body mass index show electron transport chain dysfunction, which may contribute to low muscle endurance in the current subgroup of patients...
Pulmonary gas exchange response to exercise- and mannitol-induced bronchoconstriction in mild asthmaPhillip A Munoz
Servei de Pneumologia, Institut del Tòrax, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, CIBER Enfermedades Respiratorias, Universitat de Barcelona, Spain
J Appl Physiol 105:1477-85. 2008..Va/Q inequalities during both challenges most likely reflect uneven airway narrowing and blood flow redistribution generating distinctive Va/Q patterns, including the development of areas with low and high Va/Q ratios...
Gas exchange response to short-acting beta2-agonists in chronic obstructive pulmonary disease severe exacerbationsEva Polverino
Servei de Pneumologia Institut del Tòrax, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, CIBER Enfermedades Respiratorias, Universitat de Barcelona, Barcelona, Spain
Am J Respir Crit Care Med 176:350-5. 2007..The assessment of pulmonary gas exchange after salbutamol in COPD severe exacerbations remains unknown...
