E Rial

Summary

Country: Spain

Publications

  1. pmc The mitochondrial uncoupling proteins
    Amalia Ledesma
    Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas, Velazquez 144, 28006 Madrid, Spain
    Genome Biol 3:REVIEWS3015. 2002
  2. ncbi request reprint Physiological regulation of the transport activity in the uncoupling proteins UCP1 and UCP2
    E Rial
    Centro de Investigaciones Biologicas, CSIC, Velazquez 144, 28006 Madrid, Spain
    Biochim Biophys Acta 1504:70-81. 2001
  3. ncbi request reprint Alkylsulfonates activate the uncoupling protein UCP1: implications for the transport mechanism
    Eduardo Rial
    Centro de Investigaciones Biologicas, CSIC, Ramiro de Maeztu 9, 28040, Madrid, Spain
    Biochim Biophys Acta 1608:122-30. 2004
  4. pmc Oxidative stress, thermogenesis and evolution of uncoupling proteins
    Eduardo Rial
    Centro de Investigaciones Biologicas, CSIC, Madrid, Spain
    J Biol 8:58. 2009
  5. doi request reprint Lipotoxicity, fatty acid uncoupling and mitochondrial carrier function
    Eduardo Rial
    Department of Cellular and Molecular Medicine, Centro de Investigaciones Biologicas, CSIC, Madrid, Spain
    Biochim Biophys Acta 1797:800-6. 2010
  6. doi request reprint Development of chromanes as novel inhibitors of the uncoupling proteins
    Eduardo Rial
    Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas, Madrid, Spain
    Chem Biol 18:264-74. 2011
  7. ncbi request reprint The structure and function of the brown fat uncoupling protein UCP1: current status
    E Rial
    Centro de Investigaciones Biologicas, C S I C, Madrid, Spain
    Biofactors 8:209-19. 1998
  8. ncbi request reprint Rosiglitazone up-regulates lipoprotein lipase, hormone-sensitive lipase and uncoupling protein-1, and down-regulates insulin-induced fatty acid synthase gene expression in brown adipocytes of Wistar rats
    T Teruel
    Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, Complutense University, 28040, Madrid, Spain
    Diabetologia 48:1180-8. 2005
  9. ncbi request reprint The mitochondrial uncoupling protein UCP1: a gated pore
    I Arechaga
    MRC-Dunn Human Nutrition Unit, Cambridge, United Kingdom
    IUBMB Life 52:165-73. 2001

Collaborators

Detail Information

Publications9

  1. pmc The mitochondrial uncoupling proteins
    Amalia Ledesma
    Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas, Velazquez 144, 28006 Madrid, Spain
    Genome Biol 3:REVIEWS3015. 2002
    ..UCPs are regulated at both the transcriptional level and by activation and inhibition in the mitochondrion...
  2. ncbi request reprint Physiological regulation of the transport activity in the uncoupling proteins UCP1 and UCP2
    E Rial
    Centro de Investigaciones Biologicas, CSIC, Velazquez 144, 28006 Madrid, Spain
    Biochim Biophys Acta 1504:70-81. 2001
    ..The regulation of UCP1 and UCP2 by retinoids and the lack of effects of fatty acids on UCP2 or UCP3 are starting to set differences among the new uncoupling proteins...
  3. ncbi request reprint Alkylsulfonates activate the uncoupling protein UCP1: implications for the transport mechanism
    Eduardo Rial
    Centro de Investigaciones Biologicas, CSIC, Ramiro de Maeztu 9, 28040, Madrid, Spain
    Biochim Biophys Acta 1608:122-30. 2004
    ..We propose that the fatty acid uncoupling mediated by other members of the mitochondrial transporter family probably involves a carrier to pore transition and therefore has little in common with the activation of UCP1...
  4. pmc Oxidative stress, thermogenesis and evolution of uncoupling proteins
    Eduardo Rial
    Centro de Investigaciones Biologicas, CSIC, Madrid, Spain
    J Biol 8:58. 2009
    ....
  5. doi request reprint Lipotoxicity, fatty acid uncoupling and mitochondrial carrier function
    Eduardo Rial
    Department of Cellular and Molecular Medicine, Centro de Investigaciones Biologicas, CSIC, Madrid, Spain
    Biochim Biophys Acta 1797:800-6. 2010
    ....
  6. doi request reprint Development of chromanes as novel inhibitors of the uncoupling proteins
    Eduardo Rial
    Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas, Madrid, Spain
    Chem Biol 18:264-74. 2011
    ..These findings open a promising line in the development of novel anticancer agents...
  7. ncbi request reprint The structure and function of the brown fat uncoupling protein UCP1: current status
    E Rial
    Centro de Investigaciones Biologicas, C S I C, Madrid, Spain
    Biofactors 8:209-19. 1998
    ..Mounting evidence suggest that the matrix loops contribute to the formation of the gating domain and thus they are determinants to the control of transport activity...
  8. ncbi request reprint Rosiglitazone up-regulates lipoprotein lipase, hormone-sensitive lipase and uncoupling protein-1, and down-regulates insulin-induced fatty acid synthase gene expression in brown adipocytes of Wistar rats
    T Teruel
    Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, Complutense University, 28040, Madrid, Spain
    Diabetologia 48:1180-8. 2005
    ....
  9. ncbi request reprint The mitochondrial uncoupling protein UCP1: a gated pore
    I Arechaga
    MRC-Dunn Human Nutrition Unit, Cambridge, United Kingdom
    IUBMB Life 52:165-73. 2001
    ....