M Proft

Summary

Country: Spain

Publications

  1. pmc Chipper: discovering transcription-factor targets from chromatin immunoprecipitation microarrays using variance stabilization
    Francis D Gibbons
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Longwood Avenue, Boston, MA 02115, USA
    Genome Biol 6:R96. 2005
  2. pmc Repressors and upstream repressing sequences of the stress-regulated ENA1 gene in Saccharomyces cerevisiae: bZIP protein Sko1p confers HOG-dependent osmotic regulation
    M Proft
    Instituto de Biologia Molecular y Celular de Plantas, Universidad Politecnica de Valencia CSIC, 46022 Valencia, Spain
    Mol Cell Biol 19:537-46. 1999
  3. pmc Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress
    M Proft
    Instituto de Biologia Molecular y Celular de Plantas, Universidad Politecnica de Valencia CSIC, 46022 Valencia, Spain
    EMBO J 20:1123-33. 2001
  4. ncbi request reprint Multiple levels of control regulate the yeast cAMP-response element-binding protein repressor Sko1p in response to stress
    A Pascual-Ahuir
    Instituto de Biologia Molecular y Celular de Plantas, Universidad Politecnica de Valencia, Consejo Superior de Investigaciones Cientificas, 46022 Valencia, Spain
    J Biol Chem 276:37373-8. 2001
  5. pmc The Sko1p repressor and Gcn4p activator antagonistically modulate stress-regulated transcription in Saccharomyces cerevisiae
    A Pascual-Ahuir
    Instituto de Biologia Molecular y Celular de Plantas, Universidad Politecnica de Valencia CSIC, 46022 Valencia, Spain
    Mol Cell Biol 21:16-25. 2001
  6. pmc The Ssn6-Tup1 repressor complex of Saccharomyces cerevisiae is involved in the osmotic induction of HOG-dependent and -independent genes
    J A Marquez
    Instituto de Biologia Molecular y Celular de Plantas, Universidad Politecnica de Valencia CSIC, Camino de Vera s n, 46022 Valencia, Spain
    EMBO J 17:2543-53. 1998
  7. pmc Glucose derepression of gluconeogenic enzymes in Saccharomyces cerevisiae correlates with phosphorylation of the gene activator Cat8p
    F Randez-Gil
    Institut fur Mikrobiologie, Johann Wolfgang Goethe Universitat Frankfurt, Biozentrum, Niederursel, Frankfurt am Main, Germany
    Mol Cell Biol 17:2502-10. 1997
  8. ncbi request reprint Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis
    T Jonassen
    Department of Chemistry and Biochemistry and the Molecular Biology Institute, University of California, Los Angeles, Los Angeles, California 90095, USA
    J Biol Chem 273:3351-7. 1998
  9. pmc CAT5, a new gene necessary for derepression of gluconeogenic enzymes in Saccharomyces cerevisiae
    M Proft
    Institut für Mikrobiologie der Johann Wolfgang Goethe Universität Frankfurt, Frankfurt am Main, Germany
    EMBO J 14:6116-26. 1995
  10. ncbi request reprint The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage
    M Rep
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kasteelpark Arenberg 31, B 3001 Leuven Heverlee, Belgium
    Mol Microbiol 40:1067-83. 2001

Collaborators

  • Ramon Serrano
  • Martijn Rep
  • Stefan Hohmann
  • A Pascual-Ahuir
  • Francis D Gibbons
  • F Randez-Gil
  • K D Entian
  • T Jonassen
  • J A Marquez
  • Frederick P Roth
  • Kevin Struhl
  • F Posas
  • D Hedges
  • C F Clarke
  • B N Marbois
  • J R Schultz
  • N Bojunga

Detail Information

Publications11

  1. pmc Chipper: discovering transcription-factor targets from chromatin immunoprecipitation microarrays using variance stabilization
    Francis D Gibbons
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Longwood Avenue, Boston, MA 02115, USA
    Genome Biol 6:R96. 2005
    ..The corresponding software ('Chipper') is freely available. The method described here should help reveal an organism's transcription-regulatory 'wiring diagram'...
  2. pmc Repressors and upstream repressing sequences of the stress-regulated ENA1 gene in Saccharomyces cerevisiae: bZIP protein Sko1p confers HOG-dependent osmotic regulation
    M Proft
    Instituto de Biologia Molecular y Celular de Plantas, Universidad Politecnica de Valencia CSIC, 46022 Valencia, Spain
    Mol Cell Biol 19:537-46. 1999
    ..The physiological importance of the relief from repression during salt stress was also demonstrated by the increased tolerance of sko1 or ssn6 mutants to Na+ or Li+ stress...
  3. pmc Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress
    M Proft
    Instituto de Biologia Molecular y Celular de Plantas, Universidad Politecnica de Valencia CSIC, 46022 Valencia, Spain
    EMBO J 20:1123-33. 2001
    ..Thus, Sko1 transcriptional repression is controlled directly by the Hog1 MAPK in response to stress, and this effect is further modulated by an independent signaling mechanism through the PKA pathway...
  4. ncbi request reprint Multiple levels of control regulate the yeast cAMP-response element-binding protein repressor Sko1p in response to stress
    A Pascual-Ahuir
    Instituto de Biologia Molecular y Celular de Plantas, Universidad Politecnica de Valencia, Consejo Superior de Investigaciones Cientificas, 46022 Valencia, Spain
    J Biol Chem 276:37373-8. 2001
    ....
  5. pmc The Sko1p repressor and Gcn4p activator antagonistically modulate stress-regulated transcription in Saccharomyces cerevisiae
    A Pascual-Ahuir
    Instituto de Biologia Molecular y Celular de Plantas, Universidad Politecnica de Valencia CSIC, 46022 Valencia, Spain
    Mol Cell Biol 21:16-25. 2001
    ..Together with the induction of HAL1 by amino acid starvation, these results suggest that salt stress and amino acid availability are physiologically interconnected...
  6. pmc The Ssn6-Tup1 repressor complex of Saccharomyces cerevisiae is involved in the osmotic induction of HOG-dependent and -independent genes
    J A Marquez
    Instituto de Biologia Molecular y Celular de Plantas, Universidad Politecnica de Valencia CSIC, Camino de Vera s n, 46022 Valencia, Spain
    EMBO J 17:2543-53. 1998
    ..We propose that the Ssn6-Tup1 repressor complex might be a general component in the regulation of osmostress responses at the transcriptional level of both HOG-dependent and -independent genes...
  7. pmc Glucose derepression of gluconeogenic enzymes in Saccharomyces cerevisiae correlates with phosphorylation of the gene activator Cat8p
    F Randez-Gil
    Institut fur Mikrobiologie, Johann Wolfgang Goethe Universitat Frankfurt, Biozentrum, Niederursel, Frankfurt am Main, Germany
    Mol Cell Biol 17:2502-10. 1997
    ..These results confirm our current model that glucose derepression of gluconeogenic genes needs Cat8p phosphorylation and additionally show that a still unknown transcriptional activator is also involved...
  8. ncbi request reprint Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis
    T Jonassen
    Department of Chemistry and Biochemistry and the Molecular Biology Institute, University of California, Los Angeles, Los Angeles, California 90095, USA
    J Biol Chem 273:3351-7. 1998
    ..elegans clk-1 mutants may relate to changes in the amount of ubiquinone, an essential electron transport component and a lipid soluble antioxidant...
  9. pmc CAT5, a new gene necessary for derepression of gluconeogenic enzymes in Saccharomyces cerevisiae
    M Proft
    Institut für Mikrobiologie der Johann Wolfgang Goethe Universität Frankfurt, Frankfurt am Main, Germany
    EMBO J 14:6116-26. 1995
    ....
  10. ncbi request reprint The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage
    M Rep
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kasteelpark Arenberg 31, B 3001 Leuven Heverlee, Belgium
    Mol Microbiol 40:1067-83. 2001
    ..The five Sko1p target genes described here are suitable models for studying the interplay between osmotic and oxidative responses at the molecular and physiological levels...
  11. pmc CAT8, a new zinc cluster-encoding gene necessary for derepression of gluconeogenic enzymes in the yeast Saccharomyces cerevisiae
    D Hedges
    Institut für Mikrobiologie der Johann Wolfgang Goethe Universität Frankfurt, Germany
    Mol Cell Biol 15:1915-22. 1995
    ..The observation that multicopy expression of CAT8 reverses the inability of cat1 and cat3 mutants to grow on ethanol indicates that Cat8p might be the substrate of the Cat1p/Cat3p protein kinase...