J Picazo

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..This recommendation is based on 3 pillars: argument of necessity, ethics and exemplary...

..Finally, the document should provide a detailed, stepwise management algorithm, addressing the initial empirical antimicrobial therapy and the antimicrobial therapy on days 3-5 and days 5-7 of therapy...

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..The objective of the study was to know the current situation of the antimicrobial sensitivity patterns of the main multi-resistant bacteria and to analyze any possible changes with respect to the VIRA study carried out in 2001...

..Although the recent WHO position paper on childhood immunizations speaks to the growing resistance of pneumococci, antibiotic resistance in Spain is noted to be decreasing and must be evaluated in conjunction with global studies...

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..After PCV7 implementation, non-PCV7 serotypes caused 95.5% of IPDs. The new 13-valent conjugate vaccine would provide 79.1% coverage of serotypes responsible for IPDs in this series...

..These data suggest that daptomycin could be useful for the treatment of bloodstream infections caused by staphylococci...

..6% of all streptococci tested at <or=0.5 microg/mL. Based on these results, ceftobiprole appears to be a promising agent for the treatment of infections caused by multidrug-resistant Gram-positive pathogens...

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..The carbapenems ertapenem, imipenem and meropenem and the aminoglycoside amikacin were highly active in vitro against Enterobacteriaceae isolated from intra-abdominal sites, including ESBL-producing organisms...

..The efficacy and safety profile of the candins make them the best option for treating invasive candidiasis in the critically ill patient...

..The high in vitro activity of tigecycline against tetracycline- and ciprofloxacin-resistant strains suggests a potential therapeutic role in the treatment of infections that involve Campylobacter spp...

..Increasing resistance to clindamycin and moxifloxacin was observed. Susceptibility to imipenem, piperacillin-tazobactam, and metronidazole remained unchanged...

..The results of this study confirm the excellent activity of tigecycline against multiresistant Gram-positive and Gram-negative pathogens...

..We investigated the mechanism of resistance--point mutations in domain V of 23S ribosomal RNA (rRNA) or presence of the cfr gene--involved in the outbreak...

..To study the regulatory region of a constitutively expressed erm(A) gene in Streptococcus agalactiae clinical isolates...

..faecium isolate. A total of 131 Q/D-nonsusceptible enterococci only contained the erm(B) gene. The erm(B) promoter sequence reveals no differences between the strains analyzed, regardless of the Q/D MIC value...

..The aim of the study was to ascertain the clinical and epidemiologic characteristics of patients with nosocomial or community-acquired Staphylococcus aureus bacteremic pneumonia...

..We found three isolates resistant to quinupristin/dalfopristin, all of them were erythromycin and tetracycline-resistant. For all isolates tested, linezolid MICs were <or=2 mg/l...

..The tet(M) and tet(O) genes were responsible for tetracycline resistance. Random amplification of polymorphic DNA indicated different clonal origins of the isolates...

..Heterogeneity in the susceptibility patterns and macrolide resistance phenotypes and genotypes in the different groups of VGS was detected. We found seven telithromycin-resistant S. bovis isolates all harboring the erm(B) gene...

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..fragilis group organisms to trovafloxacin and moxifloxacin and emphasizes the need to perform periodic antimicrobial susceptibility tests to guide the selection of appropriate antimicrobial therapy...

..The data from this study suggest that this new carbapenem may be useful for treating mixed infections involving Enterobacteriaceae isolates resistant to third-generation cephalosporins...

..When these vaccines become available in Europe, a reduction in hospitalizations, medical consultations, and days of work lost can be expected...

..These findings strongly suggest multiple inter-species transmission events between different non-human mammalian species and humans...

..We present two cases of Pasteurella multocida infection after a cat bite.Thus, in this article we review the most relevant clinical features related with this aetiological agent and some aspects about antimicrobial susceptibility...

..G9 rotavirus genotype was isolated in the 1980s and re-emerged without a clear explanation in the mid-1990s as one of the most frequently occurring genotypes with distinct genetic and molecular characteristics...

..Sixty-seven blood donors were used as controls. The results show that the quantitative real-time PCR assay could be of great interest for predicting CMV disease, and to monitor the onset of pre-emptive therapy...

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..DISCUSSION: Infection in general and respiratory infection in particular is frequently attended in primary care. Antibiotics are widely used in our setting and self-medication is common...

..The study was performed between December 2000 and March 2001, using two one-week time periods...