- Retinoic acid receptor alpha1 variants, RARalpha1DeltaB and RARalpha1DeltaBC, define a new class of nuclear receptor isoformsA Parrado
Laboratoire de Biologie Cellulaire Hematopoietique, INSERM U00 03, Université D Diderot Paris VII, Institut d Hematologie, Hopital Saint Louis, Paris, France
Nucleic Acids Res 29:4901-8. 2001..RARalpha1DeltaBC is an infrequent example of a functional nuclear receptor which deletes the DNA-binding domain...
- Deregulated expression of promyelocytic leukemia zinc finger protein in B-cell chronic lymphocytic leukemias does not affect cyclin A expressionA Parrado
Laboratoire de Biologie Cellulaire Hematopoietique, Universite Paris 7, France
Hematol J 1:15-27. 2000..Structurally related to BCL-6, which is involved in human lymphoma, PLZF may have a role in proliferation, differentiation and survival of hematopoietic cells, that could be mediated by transcriptional repression of the cyclin A gene...
- Functional G-CSF pathways in t(8;21) leukemic cells allow for differentiation induction and degradation of AML1-ETON Da Silva
Laboratoire de Biologie Cellulaire Hématopoïétique LBCH, INSERM E 00 03, et EA 316 Université Paris 7, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75754 Paris Cedex 10, France
Hematol J 1:316-28. 2000..The fusion protein blocks transcription and differentiation mediated by G-CSF. Interestingly, AML1-ETO leukemic cell lines are sensitive to numerous cytokines in vitro and can be induced to differentiate in the presence of G-CSF and PMA...