Patricia Munoz

Summary

Country: Spain

Publications

  1. doi request reprint Parasitic infections in solid organ transplant recipients
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón Doctor Esquerdo 46, Madrid 28007, Spain
    Infect Dis Clin North Am 24:461-95. 2010
  2. pmc Prospective Study of BK Virus Infection in Patients with Inflammatory Bowel Disease
    Virginia Flores
    Department of Digestive Diseases, General University Hospital Gregorio Marañon, Dr Esquerdo 46, 28007 Madrid, Spain CIBER Hepatic and Digestive Diseases CIBEREHD, 07110 Bunyola, Balearic Islands, Spain
    ScientificWorldJournal 2014:970528. 2014
  3. doi request reprint Invasive aspergillosis among heart transplant recipients: A 24-year perspective
    Patricia Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid Department of Medicine, Facultad de Medicina, Universidad Complutense, Madrid CIBER de Enfermedades Respiratorias CIBERES CD06 06 0058, Palma de Mallorca Red Española para la Investigación en Patología Infecciosa RD06 0008 1025, Madrid Electronic address
    J Heart Lung Transplant 33:278-88. 2014
  4. doi request reprint Central venous catheter colonization with Staphylococcus aureus is not always an indication for antimicrobial therapy
    P Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 18:877-82. 2012
  5. doi request reprint Epidemiology and risk factors of infections after solid organ transplantation
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Madrid, Spain
    Enferm Infecc Microbiol Clin 30:10-8. 2012
  6. ncbi request reprint [Prophylaxis of cytomegalovirus infection in heart transplantation]
    Patricia Munoz
    Servicio de Microbiología Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Madrid, CibeRes, GESITRA, REIPI, Espana
    Enferm Infecc Microbiol Clin 29:52-5. 2011
  7. doi request reprint Poor compliance with antifungal drug use guidelines by transplant physicians: a framework for educational guidelines and an international consensus on patient safety
    Patricia Munoz
    Microbiología Clínica Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Transplant 26:87-96. 2012
  8. doi request reprint Parasitic infections in solid-organ transplant recipients
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Madrid, Spain
    Curr Opin Organ Transplant 16:565-75. 2011
  9. doi request reprint Listeriosis: An emerging public health problem especially among the elderly
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 46, 28007 Madrid, Spain
    J Infect 64:19-33. 2012
  10. doi request reprint Gram-negative bloodstream infections
    Patricia Munoz
    Microbiology and Infectious Disease Department, Hospital General Universitario Gregorio Maranon, CIBER de Enfermedades Respiratorias, Universidad Complutense, Madrid, Spain
    Int J Antimicrob Agents 32:S10-4. 2008

Detail Information

Publications128 found, 100 shown here

  1. doi request reprint Parasitic infections in solid organ transplant recipients
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón Doctor Esquerdo 46, Madrid 28007, Spain
    Infect Dis Clin North Am 24:461-95. 2010
    ..Clinicians should include these infections in their differential diagnosis and promote adherence to preventive measures in SOT recipients...
  2. pmc Prospective Study of BK Virus Infection in Patients with Inflammatory Bowel Disease
    Virginia Flores
    Department of Digestive Diseases, General University Hospital Gregorio Marañon, Dr Esquerdo 46, 28007 Madrid, Spain CIBER Hepatic and Digestive Diseases CIBEREHD, 07110 Bunyola, Balearic Islands, Spain
    ScientificWorldJournal 2014:970528. 2014
    ..5% versus 38.5%; P = 0.096) and in those not receiving ciprofloxacin (59.5% versus 40.5%; P = 0.17). A clear impact of the immunosuppressive regimen on BKV infection could not be demonstrated. ..
  3. doi request reprint Invasive aspergillosis among heart transplant recipients: A 24-year perspective
    Patricia Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid Department of Medicine, Facultad de Medicina, Universidad Complutense, Madrid CIBER de Enfermedades Respiratorias CIBERES CD06 06 0058, Palma de Mallorca Red Española para la Investigación en Patología Infecciosa RD06 0008 1025, Madrid Electronic address
    J Heart Lung Transplant 33:278-88. 2014
    ..Despite the severity of the disease in this population, few recent series with secular trends have addressed the problem...
  4. doi request reprint Central venous catheter colonization with Staphylococcus aureus is not always an indication for antimicrobial therapy
    P Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 18:877-82. 2012
    ..aureus should be closely monitored for signs and symptoms of ongoing infection, but if these are not present then antimicrobial therapy does not seem justified...
  5. doi request reprint Epidemiology and risk factors of infections after solid organ transplantation
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Madrid, Spain
    Enferm Infecc Microbiol Clin 30:10-8. 2012
    ..Physicians attending SOT recipients should be aware of these risk factors, which include specific host characteristics, type of transplantation, microorganism and immunosuppressive policy...
  6. ncbi request reprint [Prophylaxis of cytomegalovirus infection in heart transplantation]
    Patricia Munoz
    Servicio de Microbiología Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Madrid, CibeRes, GESITRA, REIPI, Espana
    Enferm Infecc Microbiol Clin 29:52-5. 2011
    ..The use of preventive measures significantly reduces the incidence of symtomatic infection or CMV disease, which has been reported to be less than 3% in some recent series...
  7. doi request reprint Poor compliance with antifungal drug use guidelines by transplant physicians: a framework for educational guidelines and an international consensus on patient safety
    Patricia Munoz
    Microbiología Clínica Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Transplant 26:87-96. 2012
    ..An international consensus that responds to differences in patients and centers and emphasizes patient safety is clearly needed...
  8. doi request reprint Parasitic infections in solid-organ transplant recipients
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Madrid, Spain
    Curr Opin Organ Transplant 16:565-75. 2011
    ..To provide an updated perspective of the most common parasitic infections occurring in solid-organ transplant (SOT) recipients...
  9. doi request reprint Listeriosis: An emerging public health problem especially among the elderly
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 46, 28007 Madrid, Spain
    J Infect 64:19-33. 2012
    ..To analyze the incidence trend of listeriosis, its present epidemiology and the potential benefit of aminoglycosides during the last two decades...
  10. doi request reprint Gram-negative bloodstream infections
    Patricia Munoz
    Microbiology and Infectious Disease Department, Hospital General Universitario Gregorio Maranon, CIBER de Enfermedades Respiratorias, Universidad Complutense, Madrid, Spain
    Int J Antimicrob Agents 32:S10-4. 2008
    ..The present paper describes the Gram-negative organisms recovered from the blood cultures and discusses their clinical significance...
  11. ncbi request reprint The isolation of Aspergillus fumigatus from respiratory tract specimens in heart transplant recipients is highly predictive of invasive aspergillosis
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Transplantation 75:326-9. 2003
    ..However, the significance of the isolation of from respiratory specimens in heart transplant recipients is not established...
  12. doi request reprint Treatment of invasive fungal infections in immunocompromised and transplant patients: AmBiLoad trial and other new data
    Patricia Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Spain
    Int J Antimicrob Agents 32:S125-31. 2008
    ..The use of inhaled L-AmB has shown promising results for use as antifungal prophylaxis in high-risk patients...
  13. ncbi request reprint Nasal carriage of S. aureus increases the risk of surgical site infection after major heart surgery
    P Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    J Hosp Infect 68:25-31. 2008
    ..8-19.2; P=0.04) and diabetes mellitus (RR: 5.9; 95% CI: 1.8-19.2; P=0.003). Nasal carriage of S. aureus significantly increases the rate of nosocomial SSI after MHS and decolonisation strategies should be implemented in this population...
  14. ncbi request reprint Clostridium difficile-associated diarrhea in heart transplant recipients: is hypogammaglobulinemia the answer?
    Patricia Munoz
    Division of Clinical Microbiology and Infectious Diseases, Clinical Immunology Unit, Department of Cardiology, Hospital General Universitario Gregorio Maranon, University of Madrid, Madrid, Spain
    J Heart Lung Transplant 26:907-14. 2007
    ..We analyzed the incidence, clinical presentation, outcome and risk factors, including HGG, of CDAD after HT...
  15. pmc Heart valves should not be routinely cultured
    Patricia Munoz
    Department of Clinical Microbiology Infectious Diseases, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 46, 28007 Madrid, Spain
    J Clin Microbiol 46:2897-901. 2008
    ..3%. Because of its poor sensitivity and PPV, valve cultures should not be performed for patients without a clinical suspicion of IE. For patients with confirmed IE, heart valve cultures should be interpreted with caution...
  16. ncbi request reprint Cryptococcal meningitis in a patient treated with infliximab
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, University of Madrid, 28007 Madrid, Spain
    Diagn Microbiol Infect Dis 57:443-6. 2007
    ..All of them involved fungal pneumonia. Outcome was favorable in all cases...
  17. ncbi request reprint Treatment of solid organ transplant patients with invasive fungal infections: should a combination of antifungal drugs be used?
    Patricia Munoz
    Department of Clinical Microbiology, Hospital General Universitario Gregorio Maranon, University of Madrid, Spain
    Curr Opin Infect Dis 19:365-70. 2006
    ..Combined antifungal drug therapy is widely used in severe invasive mycoses in solid organ transplant (SOT) recipients. We have reviewed the available data in the literature...
  18. ncbi request reprint Mycobacterium tuberculosis infection in recipients of solid organ transplants
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Infect Dis 40:581-7. 2005
    ....
  19. ncbi request reprint Prevalence of BK virus replication among recipients of solid organ transplants
    Patricia Munoz
    Department of Clinical Microbiology Infectious Diseases, Hospital General Universitario Gregorio Maranon, University of Madrid, Madrid, Spain
    Clin Infect Dis 41:1720-5. 2005
    ..Our objective was to determine the prevalence of BKV infection for all types of SOT recipients at our medical center...
  20. ncbi request reprint Nosocomial invasive aspergillosis in a heart transplant patient acquired during a break in the HEPA air filtration system
    P Munoz
    Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 46, 28007 Madrid, Spain
    Transpl Infect Dis 6:50-4. 2004
    ..A high overload of Aspergillus spores in the intensive care unit room led this patient to acquire IA. Identical environmental and patient isolates allowed our hypothesis to be confirmed and a very precise incubation time to be estimated...
  21. ncbi request reprint Saccharomyces cerevisiae fungemia: an emerging infectious disease
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Clin Infect Dis 40:1625-34. 2005
    ..Saccharomyces cerevisiae is well known in the baking and brewing industry and is also used as a probiotic in humans. However, it is a very uncommon cause of infection in humans...
  22. ncbi request reprint Clinical-epidemiological characteristics and outcome of patients with catheter-related bloodstream infections in Europe (ESGNI-006 Study)
    P Munoz
    Clinical Microbiology and Infectious Diseases, Hospital General Gregorio Maranon, 28007 Madrid, Spain
    Clin Microbiol Infect 10:843-5. 2004
    ..In 36% of cases, catheters were implanted by physicians other than anaesthetists or surgeons, and 50% were inserted by junior staff...
  23. ncbi request reprint Risk factors of invasive aspergillosis after heart transplantation: protective role of oral itraconazole prophylaxis
    Patricia Munoz
    Department of Clinical Microbiology Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Am J Transplant 4:636-43. 2004
    ..5; 95% CI 0.3-0.8, p=0.01). We believe that antifungal prophylaxis in heart transplant patients should be offered at least to patients with one or more of these predisposing conditions...
  24. ncbi request reprint Frequency and clinical significance of bloodstream infections caused by C albicans strains with reduced susceptibility to fluconazole
    Patricia Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Diagn Microbiol Infect Dis 44:163-7. 2002
    ..In our experience, fluconazole remains a safe option for the treatment of most C. albicans fungemias, although surveillance seems advisable...
  25. ncbi request reprint Pneumocystis carinii infection in heart transplant recipients. Efficacy of a weekend prophylaxis schedule
    P Munoz
    Clinical Microbiology Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Medicine (Baltimore) 76:415-22. 1997
    ..Tolerance has been excellent. Heart transplant recipients are at a substantial risk of PCP pneumonia, which presents with an abrupt onset and a high mortality. Weekend TMP/SMX chemoprophylaxis was very effective at our institution...
  26. ncbi request reprint Criteria used when initiating antifungal therapy against Candida spp. in the intensive care unit
    P Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Gregorio Maranon, Ibiza 46, 28007, Madrid, Spain
    Int J Antimicrob Agents 15:83-90. 2000
    ..They should also be considered in patients with a colonisation index >0.5 or a corrected colonization index >0.4 or when the isolate is identified as Candida tropicalis...
  27. ncbi request reprint Lung nodular lesions in heart transplant recipients
    P Munoz
    Clinical Microbiology Infectious Diseases Division, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Heart Lung Transplant 19:660-7. 2000
    ..Ten percent of HT patients developed lung nodules that were mainly caused by Aspergillus, Nocardia, and CMV. The time of appearance and some clinical manifestations may suggest the etiology and may help in the empirical treatment...
  28. ncbi request reprint Successful outcome of Scedosporium apiospermum disseminated infection treated with voriconazole in a patient receiving corticosteroid therapy
    P Munoz
    Department of Clinical Microbiology Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Infect Dis 31:1499-501. 2000
    ..This fungi is resistant to fluconazole and amphotericin B. The infection was refractory to itraconazole, but responded successfully to voriconazole. A review of the literature is provided...
  29. ncbi request reprint Management of urinary tract infections and lymphocele in renal transplant recipients
    P Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Infect Dis 33:S53-7. 2001
    ..The incidence of lymphocele after renal transplantation varies, and its treatment is still controversial. Management options are discussed...
  30. ncbi request reprint Environmental surveillance and other control measures in the prevention of nosocomial fungal infections
    P Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 7:38-45. 2001
    ..We review the currently available Center for Disease Control recommendations and report our own experiences in the field. The indications and problems of fungal environmental and patient surveillance are also discussed...
  31. ncbi request reprint Bloodstream infections after invasive nonsurgical cardiologic procedures
    P Munoz
    Servicio de Microbiologia, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 47, Madrid 28006, Spain
    Arch Intern Med 161:2110-5. 2001
    ..To define the incidence, risk factors, and characteristics of bloodstream infections (BSIs) after invasive nonsurgical cardiologic procedures (ICPs)...
  32. doi request reprint New antifungal agents for the treatment of candidaemia
    Patricia Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Madrid, Spain
    Int J Antimicrob Agents 36:S63-9. 2010
    ..Early microbiological information and medical education may contribute to better use of these important drugs. We review the characteristics of the new antifungals used for the treatment of candidaemia...
  33. ncbi request reprint Linezolid therapy for infective endocarditis
    P Munoz
    Department of Clinical Microbiology Infectious Diseases, Hospital General Universitario Gregorio Maranon, University of Madrid, Madrid, Spain
    Clin Microbiol Infect 13:211-5. 2007
    ..The mean follow-up period was 8.5 months. Further data from randomised controlled clinical trials are needed to determine the efficacy and safety of linezolid for treating endocarditis...
  34. doi request reprint Infectious and non-infectious neurologic complications in heart transplant recipients
    Patricia Munoz
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Medicine (Baltimore) 89:166-75. 2010
    ..5% of HT recipients. Non-infectious causes clearly predominated, but infections still accounted for 32% of the episodes. New monoclonal induction therapies have contributed to diminished CNS opportunistic infections in our program...
  35. doi request reprint BK virus in liver transplant recipients: a prospective study
    B Loeches
    Clinical Microbiology and Infections Diseases Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Transplant Proc 41:1033-7. 2009
    ..The role of BK virus in nonrenal solid organ transplant recipients has not been clearly established; only anecdotal case reports have been published...
  36. ncbi request reprint Incidence and clinical characteristics of Kaposi sarcoma after solid organ transplantation in Spain: importance of seroconversion against HHV-8
    Patricia Munoz
    Department of Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Medicine (Baltimore) 81:293-304. 2002
  37. ncbi request reprint Candida krusei fungaemia: antifungal susceptibility and clinical presentation of an uncommon entity during 15 years in a single general hospital
    Patricia Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 47, 28006 Madrid, Spain
    J Antimicrob Chemother 55:188-93. 2005
    ..Candida krusei fungaemia is an uncommon entity described in immunocompromised patients previously exposed to azole agents...
  38. doi request reprint [Cardiac invasive aspergillosis in a heart transplant recipient]
    Alia Eworo
    Servicio de Microbiología Clínicay Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Departamento de Medicina, Universidad Complutense, Madrid, Espana
    Rev Iberoam Micol 28:134-8. 2011
    ..Solid organ transplant recipients are a population at risk of invasive aspergillosis. The lung and the central nervous system are usually affected...
  39. ncbi request reprint Increased incidence of pneumococcal bloodstream infections
    Marta Rodriguez-Creixems
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Pediatr Infect Dis J 22:661-3. 2003
    ..Incidence in the group <24 months of age increased from 7.4 to 78.6 episodes per 100,000 per year (P < 0.001). Overall 75% of the serogroups are included in the new heptavalent vaccine...
  40. doi request reprint Recurrent Escherichia coli bloodstream infections: epidemiology and risk factors
    Marta Sanz-García
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Ciber de enfermedades respiratorias CIBERES, Madrid, Spain
    Medicine (Baltimore) 88:77-82. 2009
    ..Recurrence of E. coli BSI is not an uncommon phenomenon and includes relapses (47%) and reinfections (53%). Recurrence should suggest not only the presence of urinary or biliary obstruction, but also the presence of immunosuppression...
  41. doi request reprint Universal prophylaxis with fluconazole for the prevention of early invasive fungal infection in low-risk liver transplant recipients
    Rafael San-Juan
    Unit of Infectious Diseases, University Hospital 12 de Octubre, Madrid, Spain
    Transplantation 92:346-50. 2011
    ..Although antifungal prophylaxis in high-risk liver transplant recipients (LTR) seems to be clearly justified, the efficacy of universal prophylaxis (UP) including low-risk patients is controversial...
  42. doi request reprint Targeted antifungal prophylaxis in heart transplant recipients
    Patricia Munoz
    1 Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain 2 Department of Cardiology, Hospital General Universitario Gregorio Maranon, Madrid, Spain 3 Department of Experimental Medicine, Hospital General Universitario Gregorio Maranon, Madrid, Spain 4 Department of Medicine, Universidad Complutense de Madrid, Madrid, Spain 5 Red Española de Investigación en Patología Infecciosa REIPI, Madrid, Spain 6 CIBER de Enfermedades Respiratorias CIBER RES, Palma de Mallorca, Spain 7 Spanish Study Group of Infections in Transplant Recipients GESITRA, Madrid, Spain 8 Department of Bioengineering and Aerospace Engineering, Universidad Carlos III de Madrid 9 Address correspondence to Patricia Muñoz, M D, Ph D, or Maricela Valerio, M D, Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 46, 28007 Madrid, Spain
    Transplantation 96:664-9. 2013
    ..Our purpose was to assess the efficacy of a personalized prophylactic approach based on the duration of the risk factors...
  43. ncbi request reprint Molecular diagnosis of infective endocarditis by real-time broad-range polymerase chain reaction (PCR) and sequencing directly from heart valve tissue
    Mercedes Marin
    Servicio de Microbiología Clínica y Enfermedades Infecciosas del Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Madrid, Spain
    Medicine (Baltimore) 86:195-202. 2007
    ..Conventional HV cultures are frequently responsible for false-positive and false-negative results, and are not always useful to establish the etiology of IE...
  44. doi request reprint Potential protective role of linezolid against Clostridium difficile infection
    Maricela Valerio
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Dr Esquerdo 46, 28007 Madrid, Spain
    Int J Antimicrob Agents 39:414-9. 2012
    ..908, 95% confidence interval 0.83-0.99; P=0.04). This work is retrospective and addresses a very particular population, but it is the first to suggest the potential impact of linezolid against CDI...
  45. doi request reprint Impact of current transplantation management on the development of cytomegalovirus disease after renal transplantation
    Rafael San Juan
    Unit of Infectious Diseases, University Hospital 12 de Octubre, Madrid, Spain
    Clin Infect Dis 47:875-82. 2008
    ..Current advances in transplantation practices may influence the development of cytomegalovirus (CMV) disease after renal transplantation...
  46. doi request reprint Impact of hepatitis C virus infection on the risk of infectious complications after kidney transplantation: data from the RESITRA/REIPI cohort
    Francisco López-Medrano
    Unit of Infectious Diseases, Hospital Universitario 12 de Octubre, Avda de Cordoba s n, Madrid, Spain
    Transplantation 92:543-9. 2011
    ..There is scarce information regarding the role of hepatitis C virus (HCV) infection in the development of infectious complications after kidney transplantation (KT)...
  47. doi request reprint Empirical treatment of candidemia in intensive care units: fluconazole or broad-spectrum antifungal agents?
    Jesus Guinea
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Med Mycol 47:515-20. 2009
    ..In conclusion, the use of broad-spectrum antifungal agents is not justified in ICUs with a low proportion of candidemia episodes caused by fluconazole-resistant strains of Candida...
  48. doi request reprint Prostatic aspergillosis in a heart transplant recipient: case report and review
    Maricela Valerio
    Department of Clinical Microbiology Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Heart Lung Transplant 28:638-46. 2009
    ..Urine culture can be negative and treatment should include long-term systemic anti-fungal therapy and, in most cases, prostatectomy...
  49. ncbi request reprint Relapsing Rhodococcus equi infection in a heart transplant recipient successfully treated with long-term linezolid
    Patricia Munoz
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense, 28007 Madrid, Spain
    Diagn Microbiol Infect Dis 60:197-9. 2008
    ..This is the 1st R. equi infection to be cured with linezolid in a heart transplant recipient...
  50. ncbi request reprint Mixed fungemia: incidence, risk factors, and mortality in a general hospital
    Julia Jensen
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Clin Infect Dis 44:e109-14. 2007
    ..We describe episodes of mixed fungemia (MF), detected between 1985 and 2006, in a large teaching hospital...
  51. ncbi request reprint A randomized and prospective study of 3 procedures for the diagnosis of catheter-related bloodstream infection without catheter withdrawal
    Emilio Bouza
    Clinical Microbiology and Infectious Diseases Service, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Infect Dis 44:820-6. 2007
    ..The objective of this study was to compare the yield of 3 microbiological procedures to assess CR-BSI without catheter withdrawal...
  52. doi request reprint Herpes simplex virus: a marker of severity in bacterial ventilator-associated pneumonia
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, 28007 Madrid, Spain
    J Crit Care 26:432.e1-6. 2011
    ..Our study aims were to determine the incidence of herpes simplex virus (HSV) in the lower respiratory tract (LRT) secretions in patients with bacterial VAP and to assess its potential clinical relevance...
  53. doi request reprint Does identification to species level provide sufficient evidence to confirm catheter-related fungemia caused by Candida albicans?
    Pilar Escribano
    Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid
    Med Mycol 51:769-73. 2013
    ..Consequently, identification of the same species from both the catheter tip and blood could be used to confirm catheter-related candidemia...
  54. ncbi request reprint Cross-sectional study of BK virus infection in pediatric kidney transplant recipients
    Marta Fogeda
    Department of Clinical Microbiology Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Pediatr Transplant 11:394-401. 2007
    ..Recipient serostatus was the most important risk factor. The rate of BKV replication and nephropathy among pediatric kidney recipients is similar to that of adults, but the incidence of graft loss is significantly lower...
  55. pmc Endemic genotypes of Candida albicans causing fungemia are frequent in the hospital
    Pilar Escribano
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Madrid, Spain
    J Clin Microbiol 51:2118-23. 2013
    ..Some of these endemic genotypes were found in the same unit of the hospital, mainly neonatology, whereas others infected patients in different wards...
  56. ncbi request reprint An instant procedure to demonstrate catheter-tip colonization may help clinicians
    Emilio Bouza
    Clinical Microbiology and Infectious Diseases Service, Hospital General Universitario Gregorio Maranon, 28007 Madrid, Spain
    Diagn Microbiol Infect Dis 56:255-60. 2006
    ..3%/100%; PPV, 86.7%/100.0%; NPV, 100%/93.9%; and full concordance, 97.0%/94.7%. Catheter-tip staining before culture is an easy-to-perform, cheap, and effective procedure to anticipate catheter colonization and rule out CRBSIs...
  57. ncbi request reprint Cultures of sternal wound and mediastinum taken at the end of heart surgery do not predict postsurgical mediastinitis
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, 28007 Madrid, Spain
    Diagn Microbiol Infect Dis 56:345-9. 2006
    ..2-97.3%), and positive (0%) and negative predictive values (96.8-98.0%). We recommend against surveillance cultures taken intraoperatively in patients undergoing MHS...
  58. doi request reprint Bloodstream infections: evolution and trends in the microbiology workload, incidence, and etiology, 1985-2006
    Marta Rodriguez-Creixems
    Microbiology and Infectious Disease Department, Hospital General Universitario Gregorio Maranon, CIBER de Enfermedades Respiratorias, Universidad Complutense, Madrid, Spain
    Medicine (Baltimore) 87:234-49. 2008
    ..Gram-positive pathogens have overtaken other etiologic agents of BSI. Our observation shows the remarkable escalation of some resistant pathogens, and the rise and relative fall of BSI in patients with HIV...
  59. pmc Is the volume of blood cultured still a significant factor in the diagnosis of bloodstream infections?
    Emilio Bouza
    Division of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    J Clin Microbiol 45:2765-9. 2007
    ..08). We conclude that the higher yield of blood cultures inoculated with lower volumes of blood reflects the conditions of the population cultured. Washington's dictum holds true today in the era of automated blood culture machines...
  60. ncbi request reprint Antimicrobial therapy of Clostridium difficile-associated diarrhea
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Dr Esquerdo 46, 28007 Madrid, Spain
    Med Clin North Am 90:1141-63. 2006
    ..The article concludes with a discussion of recent epidemic outbreaks involving CDAD...
  61. ncbi request reprint A prospective, randomized, and comparative study of 3 different methods for the diagnosis of intravascular catheter colonization
    Emilio Bouza
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Infect Dis 40:1096-100. 2005
    ....
  62. doi request reprint Long-term outcome of infective endocarditis in non-intravenous drug users
    Manuel Martinez-Selles
    Department of Cardiology, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Mayo Clin Proc 83:1213-7. 2008
    ..To describe postdischarge survival rates and late complications in non-intravenous drug users (non-IVDUs) after treatment of infective endocarditis (IE)...
  63. doi request reprint Campylobacter bacteremia: clinical characteristics, incidence, and outcome over 23 years
    Ana Fernández-Cruz
    Department of Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Madrid
    Medicine (Baltimore) 89:319-30. 2010
    ..Campylobacter bacteremia has an extraintestinal origin in as many as 31% of cases, and humoral immunodeficiency must be sought in patients with recurrent episodes. Quinolones should not be considered for empirical therapy...
  64. ncbi request reprint Bloodstream infections among heart transplant recipients
    Claudia Rodriguez
    Department of Clinical Microbiology Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Transplantation 81:384-91. 2006
    ..Heart transplant (HT) recipients are prone to life-threatening infections, including bloodstream infection (BSI), but information on this topic is particularly scarce...
  65. ncbi request reprint Invasive aspergillosis caused by cryptic Aspergillus species: a report of two consecutive episodes in a patient with leukaemia
    Teresa Pelaez
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Med Microbiol 62:474-8. 2013
    ..novofumigatus and Aspergillus viridinutans. Fungal isolates were identified to species level using traditional and sequencing-based molecular methods...
  66. doi request reprint Simultaneous monitoring of cytomegalovirus-specific antibody and T-cell levels in seropositive heart transplant recipients
    Javier Carbone
    Transplant Immunology Group, Clinical Immunology Department, Gregorio Maranon Hospital, Dr Esquerdo 46, 28007, Madrid, Spain
    J Clin Immunol 32:809-19. 2012
    ....
  67. ncbi request reprint Endotipsitis: an emerging prosthetic-related infection in patients with portal hypertension
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Diagn Microbiol Infect Dis 49:77-82. 2004
    ..Prolonged courses of antimicrobial agents can be curative, but liver transplantation is also an option to consider...
  68. ncbi request reprint Use of anaerobically incubated media to increase yield of positive blood cultures in children
    Marta Rodríguez Créixems
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Pediatr Infect Dis J 21:443-6. 2002
    ..Anaerobically incubated blood samples are also necessary in the pediatric population...
  69. doi request reprint Vancomycin MICs do not predict the outcome of methicillin-resistant Staphylococcus aureus bloodstream infections in correctly treated patients
    Loreto Rojas
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 46, 28007, Madrid, Spain
    J Antimicrob Chemother 67:1760-8. 2012
    ..5 mg/L. However, previous reports included patients treated without adjustments based on vancomycin serum levels and with different methods to evaluate MICs, which may render different results...
  70. doi request reprint Post-surgical invasive aspergillosis: an uncommon and under-appreciated entity
    Julia Jensen
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    J Infect 60:162-7. 2010
    ..Post-surgical invasive aspergillosis (PSIA) is an unusual and underestimated complication of surgery. It may occur after colonization of surgical sites by airborne Aspergillus conidia during surgery, or in the immediate postoperative...
  71. ncbi request reprint The challenge of anticipating catheter tip colonization in major heart surgery patients in the intensive care unit: are surface cultures useful?
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Crit Care Med 33:1953-60. 2005
    ..We evaluated whether skin insertion site and catheter hub surveillance cultures ("surface cultures") could predict catheter colonization and help establish the origin of bloodstream infections...
  72. ncbi request reprint Bloodstream infections: a trial of the impact of different methods of reporting positive blood culture results
    Emilio Bouza
    Division of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Clin Infect Dis 39:1161-9. 2004
    ..The impact of how positive blood culture results are reported on the evolution bloodstream infections (BSIs) has not been assessed...
  73. doi request reprint Selective intestinal decontamination with fluoroquinolones for the prevention of early bacterial infections after liver transplantation
    Rafael San-Juan
    Unit of Infectious Diseases and Digestive Surgery and Abdominal Organ Transplantation, 12 de Octubre University Hospital, Madrid, Spain
    Liver Transpl 17:896-904. 2011
    ..In conclusion, FQ-SID does not reduce the incidence of EBIs in LTRs and could be withheld from this group of patients...
  74. doi request reprint Incidence and risk factors for ventilator-associated pneumonia after major heart surgery
    Javier Hortal
    Department of Anesthesia, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Intensive Care Med 35:1518-25. 2009
    ..Major heart surgery (MHS) patients are a particularly high-risk population for nosocomial infections. Our objective was to identify risk factors for ventilator-associated pneumonia (VAP) in patients undergoing MHS...
  75. doi request reprint [Guidelines for the treatment of invasive fungal disease by Aspergillus spp. and other fungi issued by the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC). 2011 Update]
    Jesus Fortun
    Servicio de Enfermedades Infecciosas, Hospital Universitario Ramon y Cajal, Madrid, Spain
    Enferm Infecc Microbiol Clin 29:435-54. 2011
    ..Specific recommendations on the prevention of fungal infections in these patients are included...
  76. doi request reprint Continuous aspiration of subglottic secretions in the prevention of ventilator-associated pneumonia in the postoperative period of major heart surgery
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Chest 134:938-46. 2008
    ..We compared conventional and continuous aspiration of subglottic secretions (CASS) procedures in ventilated patients after major heart surgery (MHS)...
  77. doi request reprint Nocardiosis at the turn of the century
    Maricela Valerio Minero
    Department of Clinical Microbiology and Infectious Diseases Hospital General Universitario Gregorio Marañón, Universidad Complutense, Madrid, Spain
    Medicine (Baltimore) 88:250-61. 2009
    ..Larger studies of nocardiosis are required to better identify risk factors associated with mortality, and alternative and more effective methods of prevention must be developed...
  78. doi request reprint Is Candida colonization of central vascular catheters in non-candidemic, non-neutropenic patients an indication for antifungals?
    Alfonso Pérez-Parra
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Intensive Care Med 35:707-12. 2009
    ..To assess the influence of antifungal therapy on the outcome of non-candidemic adult patients with central vascular catheter (CVC) tips colonized by Candida species...
  79. doi request reprint Empiric therapy for intravenous central line infections and nosocomially-acquired acute bacterial endocarditis
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Crit Care Clin 24:293-312, viii-ix. 2008
    ..Extra coverage for Gram-negative bacilli should be administered in severely ill or immunocompromised patients. Once culture and sensitivity results are known, antibiotic therapy can be more selective...
  80. pmc Ventilator-associated pneumonia in patients undergoing major heart surgery: an incidence study in Europe
    Javier Hortal
    Anaesthesia Department, Hospital General Universitario Gregorio Maranon, 28007 Madrid, Spain
    Crit Care 13:R80. 2009
    ..Our aim was to determine the incidence, aetiology, risk factors and outcome of ventilator-associated pneumonia (VAP) in patients who have undergone MHS in Europe...
  81. ncbi request reprint Value of a single galactomannan determination (Platelia) for the diagnosis of invasive aspergillosis in non-hematological patients with clinical isolation of Aspergillus spp
    Jesus Guinea
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Spain
    Med Mycol 46:575-9. 2008
    ..15%/100%, and 93.55%/92.86% (p=0.001 and p<0.001), respectively. The determination of galactomannan in the sera of non-neutropenic patients could prove to be a useful microbiological finding when diagnosing invasive aspergillosis...
  82. ncbi request reprint Ventilator-associated pneumonia after heart surgery: a prospective analysis and the value of surveillance
    Emilio Bouza
    Department of Clinical Microbiology and Infectious Disease, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Crit Care Med 31:1964-70. 2003
    ..To study the predictive role of systematic surveillance cultures...
  83. pmc Tropheryma whipplei infective endocarditis as the only manifestation of Whipple's disease
    Mercedes Marin
    Servicio de Microbiología Clínica y Enfermedades, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Clin Microbiol 45:2078-81. 2007
    ..The case was diagnosed using broad-range PCR and confirmed by specific PCRs. We review the cases of infective endocarditis presenting as the only manifestation of Whipple's disease reported in the literature...
  84. doi request reprint Severe, non-bacteremic infections in ICU patients
    Jose M Aguado
    Unidad de Enfermedades Infecciosas, Hospital Universitario 12 de Octubre, Universidad Complutense, Madrid, Spain
    Enferm Infecc Microbiol Clin 29:1-9. 2011
    ..One of the members of the group discussed the content of each of the selected papers, with a critical appraisal by other members of the panel...
  85. doi request reprint Epidemiology of candidemia in intensive care units
    Emilio Bouza
    Servicio de Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Red de Investigací on en Patología Infecciosa, Spain
    Int J Antimicrob Agents 32:S87-91. 2008
    ..Candidemia in ICUs is associated with a considerable increase in hospital costs and length of hospital stay...
  86. pmc Impact of zygomycosis on microbiology workload: a survey study in Spain
    Marta Torres-Narbona
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    J Clin Microbiol 45:2051-3. 2007
    ..Less than 8% of the patients who harbored zygomycete isolates had zygomycosis. The incidence of zygomycosis (6 cases) was 0.43 cases/1,000,000 inhabitants and 0.62 cases/100,000 hospital admissions...
  87. ncbi request reprint A needleless closed system device (CLAVE) protects from intravascular catheter tip and hub colonization: a prospective randomized study
    E Bouza
    Department of Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, University of Madrid, Madrid, Spain
    J Hosp Infect 54:279-87. 2003
    ..Multivariate analysis showed that CLAVE use was an independent protective factor for tip colonization. CLAVE offered significant protection from catheter-tip and hub colonization...
  88. ncbi request reprint Demolition of a hospital building by controlled explosion: the impact on filamentous fungal load in internal and external air
    E Bouza
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, University of Madrid, Madrid, Spain
    J Hosp Infect 52:234-42. 2002
    ..Demolition work was associated with a significant increase in the fungal colony counts of hospital external and non-protected internal air. Effective protective measures may be taken to avoid the emergence of clinical infections...
  89. ncbi request reprint Pacemaker infection due to Mycobacterium fortuitum: the role of universal 16S rRNA gene PCR and sequencing
    Maddalena Giannella
    Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, 28007 Madrid, Spain
    Diagn Microbiol Infect Dis 57:337-9. 2007
    ..We present a review of the literature and report a case of pacemaker infection due to Mycobacterium fortuitum rapidly detected by universal 16S rRNA gene polymerase chain reaction and sequencing...
  90. doi request reprint Prophylaxis with caspofungin for invasive fungal infections in high-risk liver transplant recipients
    Jesus Fortun
    Department of Infectious Diseases, Ramon y Cajal Hospital, Madrid, Spain
    Transplantation 87:424-35. 2009
    ..The aim of this prospective, multicenter, noncomparative, open-label trial was to evaluate the prophylactic use of caspofungin in adult liver transplant recipients at high risk of developing invasive fungal infections (IFI)...
  91. ncbi request reprint Postoperative infections after major heart surgery and prevention of ventilator-associated pneumonia: a one-day European prevalence study (ESGNI-008)
    E Bouza
    Servicio de Microbiología Clínica y Enfermedades Infecciosas VIH, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Hosp Infect 64:224-30. 2006
    ....
  92. ncbi request reprint A European perspective on intravascular catheter-related infections: report on the microbiology workload, aetiology and antimicrobial susceptibility (ESGNI-005 Study)
    E Bouza
    Clinical Microbiology and Infectious Diseases, Hospital General Gregorio Maranon, 28007 Madrid, Spain
    Clin Microbiol Infect 10:838-42. 2004
    ..4% of coagulase-negative staphylococcus isolates. Of 37 Gram-negative isolates, 35% were resistant to cefotaxime, 31% to ceftazidime, and 27% to ciprofloxacin. Imipenem and cefepime had the lowest reported rates of resistance (11%)...
  93. doi request reprint Tuberculosis in solid-organ transplant recipients: consensus statement of the group for the study of infection in transplant recipients (GESITRA) of the Spanish Society of Infectious Diseases and Clinical Microbiology
    Jose Maria Aguado
    Unidad de Enfermedades Infecciosas, Hospital Universitario 12 de Octubre, Madrid, Spain
    Clin Infect Dis 48:1276-84. 2009
    ....
  94. ncbi request reprint A European perspective on nosocomial urinary tract infections II. Report on incidence, clinical characteristics and outcome (ESGNI-004 study). European Study Group on Nosocomial Infection
    E Bouza
    Servicio de Microbiologia, Clínica y Enfermedades Infecciosas VIH, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 7:532-42. 2001
    ..To estimate the incidence of nosocomially acquired urinary tract infections (NAUTI) in Europe and provide information on the clinical characteristics, underlying conditions, etiology, management and outcome of patients...
  95. ncbi request reprint Haemophilus species bacteremia in adults. The importance of the human immunodeficiency virus epidemic
    P Munoz
    Servicio de Microbiología y Enfermedades Infecciosas VIH, Hospital General Universitario, Gregorio Maranon, Madrid, Spain
    Arch Intern Med 157:1869-73. 1997
    ..Until the late 1970s, invasive infections caused by Haemophilus species were thought to occur mainly in children and only infrequently in adults...
  96. ncbi request reprint Catheter-related infections: diagnosis and intravascular treatment
    E Bouza
    Servicio de Microbiología Clínica y E Infecciosas, Hospital General Universitario Gregorio Marafñón, Universidad Complutense, Madrid, Spain
    J Chemother 13:224-33. 2001
    ..New diagnostic and therapeutic techniques may avoid the unnecessary withdrawal of thousands of efficient, difficult to replace and expensive intravascular lines...
  97. ncbi request reprint Catheter-related infections: diagnosis and intravascular treatment
    E Bouza
    Servicio de Microbiología Clínica y E Infecciosas, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    Clin Microbiol Infect 8:265-74. 2002
    ..New diagnostic and therapeutic techniques may avoid the unnecessary withdrawal of thousands of efficient, difficult to replace and expensive intravascular lines...
  98. ncbi request reprint A prospective search for ocular lesions in hospitalized patients with significant bacteremia
    E Bouza
    Serviciode Microbiología Clínica y E Infecciosas, Hospital General Universitario Gregorio Maranon, 28007 Madrid, Spain
    Clin Infect Dis 30:306-12. 2000
    ....
  99. ncbi request reprint Nosocomial bloodstream infections caused by Streptococcus pneumoniae
    E Bouza
    Division of Clinical Microbiology, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Clin Microbiol Infect 11:919-24. 2005
    ..7; 95% CI, 4.9--820.7; p<0.001). Adequate empirical therapy was an independent protective factor (OR, 0.05; 95% CI, 0.04--0.58; p<0.005), but the use of more than one antimicrobial agent was not...
  100. ncbi request reprint Infections following major heart surgery in European intensive care units: there is room for improvement (ESGNI 007 Study)
    E Bouza
    Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Hosp Infect 63:399-405. 2006
    ..MHS ICUs in Europe still have a high rate of postoperative infections. Well-recognized routine practices for the diagnosis and treatment of VAP are not implemented regularly in many European institutions...
  101. pmc Workload due to Aspergillus fumigatus and significance of the organism in the microbiology laboratory of a general hospital
    E Bouza
    Clinical Microbiology and Infectious Diseases Department, Servicio de Microbiologia, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain
    J Clin Microbiol 43:2075-9. 2005
    ..A simple score based on five easily available parameters may be of help to microbiologists and clinicians to predict the risk of IA...