Research Topics
| F MorenoSummaryCountry: Spain Publications
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Publications
Glucose sensing through the Hxk2-dependent signalling pathwayF Moreno
Departamento de Bioquimica y Biologia Molecular, Universidad de Oviedo, 33006 Oviedo, Spain
Biochem Soc Trans 33:265-8. 2005..Our findings show that the main role of Hxk2 in the glucose signalling pathway is the interaction with Mig1 to generate a repressor complex located in the nucleus of S. cerevisiae...
Imaging and mapping protein-binding sites on DNA regulatory regions with atomic force microscopyF Moreno Herrero
, , 33006 Oviedo, Spain
Biochem Biophys Res Commun 280:151-7. 2001..Our results allow us to define Mig1p as a new factor probably contributing to the carbon source-dependent transcription regulation of HXK2 gene...
Mediator factor Med8p interacts with the hexokinase 2: implication in the glucose signalling pathway of Saccharomyces cerevisiaeT de la Cera
Departamento de Bioquimica y Biologia Molecular, Inst Univ de Biotoecn de Asturias, Universidad de Oviedo, 33006 Oviedo, Spain
J Mol Biol 319:703-14. 2002..We conclude that Hxk2p operates through the MED8 site, by interacting with Med8p, in the glucose signal transduction pathway of Saccharomyces cerevisiae...
Tpk3 and Snf1 protein kinases regulate Rgt1 association with Saccharomyces cerevisiae HXK2 promoterA Palomino
Departamento de Bioquimica y Biologia Molecular, Universidad de Oviedo, 33006 Oviedo, Spain
Nucleic Acids Res 34:1427-38. 2006..These results suggest that a novel silent-chromatin loop is responsible for Rgt1-dependent transcriptional regulation of the HXK2 gene...
Analysis by atomic force microscopy of Med8 binding to cis-acting regulatory elements of the SUC2 and HXK2 genes of saccharomyces cerevisiaeF Moreno Herrero
Departamento de Bioquimica y Biologia Molecular, Instituto Universitario de Biotecnologia de Asturias, Universidad de Oviedo, 33006, Oviedo, Spain
FEBS Lett 459:427-32. 1999..No preference for binding either of the two UASs of SUC2 promoter as well as for the two DRSs of HXK2 gene has been found. We also discuss whether this protein works as dimer or as a monomer...
The hexokinase 2 protein regulates the expression of the GLK1, HXK1 and HXK2 genes of Saccharomyces cerevisiaeA Rodriguez
Departamento de Bioquimica y Biologia Molecular, Instituto Universitario de Biotecnologia de Asturias, Universidad de Oviedo, 33006 Oviedo, Spain
Biochem J 355:625-31. 2001....
Med8, a subunit of the mediator CTD complex of RNA polymerase II, directly binds to regulatory elements of SUC2 and HXK2 genesR S Chaves
Instituto Universitario de Biotecnologia de Asturias, Universidad de Oviedo, Oviedo, 33006, Spain
Biochem Biophys Res Commun 254:345-50. 1999..Thus, the role of Med8 could be to act as coupling factor by linking activating and repressing transcription complexes to the RNA polymerase II holoenzyme transcriptional machinery...
Mechanism of inactivation of UDP-glucose 4-epimerase from Saccharomyces cerevisiae by D-xylose and L-arabinoseR S Carmenes
Departamento Interfacultativo de Bioquimica, Universidad de Oviedo, Spain
Yeast 2:101-8. 1986..In vivo studies showed that epimerase is inactivated to a smaller extent when 1% D-galactose is present in the culture medium than when 1% ethanol is the main carbon source...
The ICL1 gene from Saccharomyces cerevisiaeE Fernandez
Departamento de Biologia Funcional, Facultad de Medicina, Universidad de Oviedo, Spain
Eur J Biochem 204:983-90. 1992..Two putative cAMP-dependent protein-kinase phosphorylation sites may explain the susceptibility of the enzyme to carbon catabolite inactivation...
Hexokinase PII has a double cytosolic-nuclear localisation in Saccharomyces cerevisiaeF Randez Gil
Departamento de Biotecnologia de Alimentos, Instituto de Agroquimica y Tecnologia de Alimentos, CSIC, Burjassot Valencia, Spain
FEBS Lett 425:475-8. 1998....
sbmC, a stationary-phase induced SOS Escherichia coli gene, whose product protects cells from the DNA replication inhibitor microcin B17M R Baquero
Unidad de Genetica Molecular, Hospital Ramon y Cajal, Madrid, Spain
Mol Microbiol 18:301-11. 1995..The gene product, SbmC, also blocks MccB17 export from producing cells. Altogether, our results suggest that SbmC recognizes and sequesters MccB17 in a reversible way...
