Research Topics
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Publications
Circuit life span in critically ill children on continuous renal replacement treatment: a prospective observational evaluation studyJimena del Castillo
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Madrid, Spain
Crit Care 12:R93. 2008..Few studies have monitored circuit function prospectively. The purpose of this study was to determine the variables associated with circuit life in critically ill children with CRRT...
Pediatric defibrillation after cardiac arrest: initial response and outcomeAntonio Rodríguez-Núñez
Pediatric Emergency and Critical Care Division, Department ofPediatrics, Hospital Clinico Universitario de Santiago de Compostela, Spain
Crit Care 10:R113. 2006..Shockable rhythms are rare in pediatric cardiac arrest and the results of defibrillation are uncertain. The objective of this study was to analyze the results of cardiopulmonary resuscitation that included defibrillation in children...
Complications of continuous renal replacement therapy in critically ill children: a prospective observational evaluation studyMaria J Santiago
Pediatric Intensive Care Service, Hospital General Universitario Gregorio Maranon, Dr Castelo Madrid, 28009, Spain
Crit Care 13:R184. 2009..However, no studies have analyzed these complications prospectively. The purpose of this study was to analyze the complications of CRRT in children and to study the associated risk factors...
Rescue treatment with terlipressin in children with refractory septic shock: a clinical studyAntonio Rodríguez-Núñez
Pediatric Emergency and Critical Care Division, Department of Pediatrics, Hospital Clinico Universitario de Santiago de Compostela, Servicio Galego de Saude and University of Santiago de Compostela, Spain
Crit Care 10:R20. 2006..The purpose of the present study is to report the effects of terlipressin (TP) as a rescue treatment in children with catecholamine refractory hypotensive septic shock...
[Energy expenditure in critically ill children: correlation with clinical characteristics, caloric intake, and predictive equations]J Lopez-Herce Cid
Seccion de Cuidados Intensivos Pediatricos, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Espana
An Pediatr (Barc) 66:229-39. 2007..To study energy expenditure (EE) in critically ill infants and children and its correlation with clinical characteristics, treatment, nutrition, caloric intake, and predicted energy expenditure calculated through theoretical formulas...
Clinical course of children requiring prolonged continuous renal replacement therapyJesús López-Herce
Pediatric Intensive Care Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Pediatr Nephrol 25:523-8. 2010..Patients with prolonged CRRT required more frequent hemodiafiltration and higher doses of heparin. Mortality was slightly higher in children with longer CRRT, though this difference did not reach statistical significance...
Postpyloric enteral nutrition in the critically ill child with shock: a prospective observational studyJesús López-Herce
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Nutr J 7:6. 2008..The purpose of the study was to analyze the characteristics of enteral nutrition and its tolerance in the critically ill child with shock and to compare this with non-shocked patients...
[The effect of helium on ventilator parameters: in vitro study with a Servoi ventilator]J Lopez-Herce Cid
Sección de Cuidados Intensivos Pediátricos Hospital General Universitario Gregorio Marañón Madrid España
An Pediatr (Barc) 68:336-41. 2008..To analyze the changes in respiratory parameters in a Servoi ventilator with heliox...
Cardiac output and blood volume parameters using femoral arterial thermodilutionJesús López-Herce
Pediatric Intensive Care Unit, Gregorio Maranon General University Hospital, Madrid, Spain
Pediatr Int 51:59-65. 2009..The normal values in children have not been defined. The purpose of the present paper was therefore to evaluate cardiac output and parameters of blood volume using femoral arterial thermodilution in critically ill children...
Characteristics and outcome of cardiorespiratory arrest in childrenJesús López-Herce
Arzobispo Morcillo 28029 Madrid, Spain
Resuscitation 63:311-20. 2004..To analyse the present day characteristics and outcome of cardio-respiratory arrest in children in Spain...
[Risk factors for prolonged mechanical ventilation after cardiac surgery in children]Jesús López-Herce Cid
Sección de Cuidados Intensivos Pediátricos Hospital General Universitario Gregorio Marañón Madrid España
Med Intensiva 32:369-77. 2008..To study the postoperative factors associated with prolonged mechanical ventilation after cardiac surgery in children...
A child presenting with acute renal failure secondary to a high dose of indomethacin: a case reportFelipe Gonzalez
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Maranon, Universidad Complutense de Madrid, Madrid, Spain
J Med Case Reports 3:47. 2009..The aim of this article is to describe acute renal failure secondary to a high dose of indomethacin in a child and to review an error in a supervised drug prescription and administration system...
Gastrointestinal complications in critically ill patients: what differs between adults and children?Jesús López-Herce
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Curr Opin Clin Nutr Metab Care 12:180-5. 2009..The objective of this review has been to analyse and compare the causes, incidence, severity and treatment of gastrointestinal complications in critically ill children and adults...
Hypoventilation due to reinhalation in infants with a transport ventilatorJesús López-Herce
Seccion de Cuidados Intensivos Pediatricos, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Pediatr Emerg Care 25:588-9. 2009..Capnography and transcutaneous PCO2 are useful for the early detection of hypercapnia and the dead space during the transfer of pediatric patients...
Risk factors for gastrointestinal complications in critically ill children with transpyloric enteral nutritionJ Lopez-Herce
Pediatric Intensive Care Unit, Preventive and Quality Control Service DV, Gregorio Maranon General University Hospital, Madrid, Spain
Eur J Clin Nutr 62:395-400. 2008..To study the risk factors for gastrointestinal complications related to enteral nutrition in critically ill children...
Terlipressin versus adrenaline in an infant animal model of asphyxial cardiac arrestJesús López-Herce
Pediatric Intensive Care Service, Hospital General Universitario Gregorio Maranon, Dr Castelo 47, 28009, Madrid, Spain
Intensive Care Med 36:1248-55. 2010..The objective of this study was to compare the efficacy of terlipressin versus adrenaline in an experimental infant animal model of asphyxial cardiac arrest (ACA)...
Elevated carboxyhemoglobin associated with sodium nitroprusside treatmentJesús López-Herce
Pediatric Critical Care Unit, Gregorio Marañón University Hospital, Dr Castelo 47, 28009 Madrid, Spain
Intensive Care Med 31:1235-8. 2005..To report four cases of carboxyhemoglobinemia associated with high doses of sodium nitroprusside after cardiac transplant in children...
Outcome of out-of-hospital cardiorespiratory arrest in childrenJesús López-Herce
Gregorio Maranon Hospital, Madrid, Spain
Pediatr Emerg Care 21:807-15. 2005..To analyze the characteristics and outcome of out-of-hospital cardiorespiratory arrest in children in Spain...
Continuous venovenous renal replacement therapy with a pulsatile tubular blood pump: analysis of efficacy parametersJesús López-Herce
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Artif Organs 30:64-9. 2006..The ultrafiltrate flow increases in relation to the blood flow, the frequency of the pump, and the diastolic time...
Haemodynamic response to acute hypovolaemia, rapid blood volume expansion and adrenaline administration in an infant animal modelJesús López-Herce
Paediatric Intensive Care Unit, Seccion de Cuidados Intensivos Pediatricos, Hospital General Universitario Gregorio Maranon, Dr Castelo, 49, 28007 Madrid, Spain
Resuscitation 68:259-65. 2006..ITBI and GEDVI are more sensitive to changes in blood volume than CVP and PCP. Rapid blood volume expansion and adrenaline administration do not affect extravascular lung water...
Correlation between cardiac output measured by the femoral arterial thermodilution technique pulmonary arterial and that measured by contour pulse analysis in a paediatric animal modelJesús López-Herce
Paediatric Intensive Care Unit, Gregorio Maranon Hospital, Dr Castelo 47, 28009 Madrid, Spain
J Clin Monit Comput 20:19-23. 2006..To evaluate the correlation between two methods for the determination of cardiac output: the femoral arterial thermodilution technique (FATD) and the arterial pulse contour analysis (PCCO) using the PiCCO catheter...
Effects of initiation of continuous renal replacement therapy on hemodynamics in a pediatric animal modelJesús López-Herce
Pediatric Intensive Care Unit, Gregorio Marañón University Hospital, Madrid, Spain
Ren Fail 28:171-6. 2006..We conclude that CRRT in a pediatric animal model induces initial hypovolemia, and a systemic cardiovascular response with vasoconstriction and increase in ventricular contractility...
Estimation of the parameters of cardiac function and of blood volume by arterial thermodilution in an infant animal modelJesús López-Herce
Paediatric Intensive Care Unit, Gregorio Maranon Hospital, Madrid, Spain
Paediatr Anaesth 16:635-40. 2006..The objective of this study has been to analyze the values of cardiac function and blood volume in an infant animal model using the arterial thermodilution technique...
Transpyloric enteral nutrition in the critically ill child with renal failureJesús López-Herce
Gregorio Maranon General University Hospital, Paediatric Intensive Care Unit, Dr Castelo 47, 28009 Madrid, Spain
Intensive Care Med 32:1599-605. 2006..To study the efficacy and tolerance of transpyloric enteral nutrition (TEN) in the critically ill child with acute renal failure (ARF)...
[Characteristics and evolution of cardiopulmonary arrest in children in Spain: comparison between autonomous communities]J Lopez-Herce Cid
Hospital Gregorio Marañón Madrid España
Med Intensiva 30:204-11. 2006..We do not know if these differences could have influenced the characteristics and evolution of cardiopulmonary arrest in children...
[Cardiorespiratory arrest in children with trauma]J Lopez-Herce Cid
Seccion de Cuidados Intensivos Pediatricos, Hospital General Universitario Gregorio Maranon, Madrid, Espana
An Pediatr (Barc) 65:439-47. 2006..To analyze the characteristics and outcome of cardiorespiratory arrest secondary to trauma in children...
Hemodynamic, respiratory, and perfusion parameters during asphyxia, resuscitation, and post-resuscitation in a pediatric model of cardiac arrestJesús López-Herce
Pediatric Intensive Care Service, Hospital General Universitario Gregorio Maranon, Dr Castelo 47, 28009 Madrid, Spain
Intensive Care Med 37:147-55. 2011..To analyze the evolution of hemodynamic, respiratory, and tissue perfusion parameters in an infant animal model of asphyxial cardiac arrest (CA)...
Assessment of the level of sedation in children after cardiac surgeryAdelaida Lamas
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Ann Thorac Surg 88:144-50. 2009..There is no reference method for the evaluation of the level of sedation in children after cardiac surgery. The utility of the bispectral index and middle latency auditory evoked potentials has not been evaluated...
Assessing sedation in critically ill children by bispectral index, auditory-evoked potentials and clinical scalesAdelaida Lamas
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Intensive Care Med 34:2092-9. 2008....
Clinical course and mortality risk factors in critically ill children requiring continuous renal replacement therapyMaria J Santiago
Pediatric Intensive Care Service, Hospital General Universitario Gregorio Maranon, Dr Castelo 47, Madrid, Spain
Intensive Care Med 36:843-9. 2010..To study the clinical course in children requiring continuous renal replacement therapy (CRRT) and to analyse factors associated with mortality...
Correlations between hemodynamic, oxygenation and tissue perfusion parameters during asphyxial cardiac arrest and resuscitation in a pediatric animal modelJesús López-Herce
Pediatric Intensive Care Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Resuscitation 82:755-9. 2011..To analyze the correlations between hemodynamic, oxygenation and tissue perfusion values in an infant animal model of asphyctic cardiac arrest (ACA)...
Relationship between energy expenditure, nutritional status and clinical severity before starting enteral nutrition in critically ill childrenMarta Botrán
Paediatric Intensive Care Department, Hospital General Universitario Gregorio Maranon, Dr Castelo 47, Madrid, Spain
Br J Nutr 105:731-7. 2011..Finally, it was concluded that neither nutritional status nor clinical severity is related to EE. Therefore, EE must be measured individually in each critically ill child using indirect calorimetry...
Bispectral index and middle latency auditory evoked potentials in children younger than two-years-oldAdelaida Lamas
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Anesth Analg 106:426-32, table of contents. 2008....
Chest compressions versus ventilation plus chest compressions in a pediatric asphyxial cardiac arrest animal modelJose María Iglesias
Pediatric Intensive Care Service, Hospital General Universitario Gregorio Maranon, Dr Castelo 47, 28009, Madrid, Spain
Intensive Care Med 36:712-6. 2010..To compare the ventilation achieved with chest compressions (CC) or ventilation plus compressions (VC) in a pediatric animal model of cardiac arrest...
The use of continuous renal replacement therapy in series with extracorporeal membrane oxygenationMaria J Santiago
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Kidney Int 76:1289-92. 2009..For these reasons, this may be a good method for performing CRRT in patients on ECMO...
Measurement of cardiac output in children by bioreactanceYolanda Ballestero
Pediatric Intensive Care Department, Hospital General Universitario Gregorio Maranon, 28009, Madrid, Spain
Pediatr Cardiol 32:469-72. 2011..These data suggest that this method is not useful for evaluating CI in small children...
Hypophosphatemia and phosphate supplementation during continuous renal replacement therapy in childrenMaria José Santiago
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Kidney Int 75:312-6. 2009..Further, we show that the addition of phosphate to replacement and dialysate solutions is safe and that it reduces the incidence of hypophosphatemia and the need for intravenous phosphate treatment...
Enteral nutrition in the critically ill child: comparison of standard and protein-enriched dietsMarta Botrán
Pediatric Intensive Care Department, General Hospital of Gregorio Marañón University, Madrid, Spain
J Pediatr 159:27-32.e1. 2011..To compare a standard diet and a protein-enriched diet in critically ill children...
Stability of continuous renal replacement therapy solutions after phosphate addition: an experimental studyMaria José Santiago
Pediatric Intensive Care Department, Hospital General Universitario Gregorio Maranon, Pediatric Laboratory Department, Madrid, Spain
Ther Apher Dial 15:75-80. 2011..There were no visible signs of precipitation up to 48 h. The addition of phosphate to the CRRT fluids at concentrations of up to 7.7 mg/dL does not cause problems with precipitation or instability of the mixture...
Comparison of continuous pH-meter and intermittent pH paper monitoring of gastric pH in critically ill childrenMaria Jose Solana
Pediatric Intensive Care Department, Hospital General Universitario Gregorio Maranon, Dr Castelo 47, Madrid, Spain
Eur J Gastroenterol Hepatol 24:33-6. 2012..The objective of this study was to compare these two methods of pH measurement...
Clinical severity scores do not predict tolerance to enteral nutrition in critically ill childrenCesar Sanchez
Department of Paediatric Gastroenterology, Hepatology and Nutrition, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Br J Nutr 102:191-4. 2009..However, their ability to predict digestive tract complications is low...
Accuracy of three transcutaneous carbon dioxide monitors in critically ill childrenJavier Urbano
Research Assistant Contract, Spanish Health Research Fund Fondo de Investigaciones Sanitarias, Instituto de Salud Carlos III, Madrid, Spain
Pediatr Pulmonol 45:481-6. 2010..To study the accuracy of three devices for measuring transcutaneous CO(2) tension in critically ill children...
Neostigmine in the treatment of refractory constipation in critically ill childrenRafael Gonzalez
Pediatric Intensive Care Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
J Pediatr Gastroenterol Nutr 53:224-6. 2011..There were no adverse effects. We conclude that continuous intravenous neostigmine can be effective in critically ill children with refractory constipation. Further studies are necessary to determine the dose and safety of the treatment...
Pulmonary arterial thermodilution, femoral arterial thermodilution and bioreactance cardiac output monitoring in a pediatric hemorrhagic hypovolemic shock modelYolanda Ballestero
Pediatric Intensive Care Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense Madrid, Spain
Resuscitation 83:125-9. 2012..Bioreactance is a new non-invasive method for cardiac output measurement (NICOM). There are no studies that have analysed the utility of this technique in a pediatric animal model of hemorrhagic shock...
Chest compressions versus ventilation plus chest compressions: a randomized trial in a pediatric asphyxial cardiac arrest animal modelMarta Botrán
Pediatric Intensive Care Department, Hospital General Universitario Gregorio Maranon, C Doctor Castelo 47, 28009, Madrid, Spain
Intensive Care Med 37:1873-80. 2011..To compare survival, oxygenation, ventilation, and hemodynamic variables achieved with chest compressions or ventilation plus chest compressions...
Analysis of bispectral index and middle latency auditory-evoked potentials parameters in critically ill childrenAdelaida Lamas
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
J Clin Neurophysiol 26:150-4. 2009..These variations are a consequence of the electroencephalographic structure at young ages and are secondary to the higher proportion of slow waves in deep states of sedation...
Monitoring sedation in the critically ill childA Lamas
Paediatric Intensive Care Service, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Anaesthesia 65:516-24. 2010..The bispectral index is the most widely used method at the present time. Analysis and comparison of the efficacy of the different methods for evaluating sedation in the critically ill child is required...
Pediatric cardiac arrest refractory to advanced life support: is there a role for terlipressin?Javier Gil-Antón
Pediatric Intensive Care Unit, Hospital de Cruces, Barakaldo, Bizkaia, Spain
Pediatr Crit Care Med 11:139-41. 2010....
Early transpyloric enteral nutrition in critically ill childrenCesar Sanchez
Paediatric Intensive Care Unit, Gregorio Maranon General University Hospital, Madrid, Spain
Nutrition 23:16-22. 2007..We compared the tolerance of early (within the first 24 h after admission to the pediatric intensive care unit) and late transpyloric enteral nutrition in critically ill children...
A paediatric cardiopulmonary resuscitation training project in HondurasJavier Urbano
Hospital General Universitario Gregorio Maranon, Madrid, Spain
Resuscitation 81:472-6. 2010..The objective of this paper is to describe the design and present the results of a European paediatric and neonatal CPR training programme adapted to Honduras...
Hypotonic versus isotonic maintenance fluids in critically ill children: a multicenter prospective randomized studyCorsino Rey
Paediatric Intensive Care Unit, Department of Paediatrics, Hospital Universitario Central de Asturias, University of Oviedo, Oviedo, Asturias, Spain
Acta Paediatr 100:1138-43. 2011..Study the influence of hypotonic (HT) and isotonic (IT) maintenance fluids in the incidence of dysnatraemias in critically ill children...
A survey on training in pediatric cardiopulmonary resuscitation in Latin America, Spain, and PortugalJesús López-Herce
Pediatric Intensive Care Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Pediatr Crit Care Med 12:e200-4. 2011..To determine how training in pediatric cardiopulmonary resuscitation is provided in the Iberoamerican countries...
Varicella encephalopathy in immunocompetent childrenAmparo Carreño
Paediatric Intensive Care Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
J Paediatr Child Health 43:193-5. 2007..Two previously healthy girls presented acute encephalopathy due to varicella, with severe alteration of the conscious level and seizures. Both patients improved progressively after 15 days, with complete clinical recovery...
