Research Topics
Genomes and Genes | Santiago Montes-MorenoSummaryCountry: Spain Publications
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Publications
SPIB, a novel immunohistochemical marker for human blastic plasmacytoid dendritic cell neoplasms: characterization of its expression in major hematolymphoid neoplasmsSantiago Montes-Moreno
Pathology Department, Hospital Universitario Marques de Valdecilla, Instituto de Formación e Investigación Marqués de Valdecilla, Santander, Spain
Blood 121:643-7. 2013..We conclude that SPIB expression can be used as a tool for diagnosing BPDC neoplasms, but it needs to be tested in conjunction with the growing arsenal of markers for human plasmacytoid dendritic cells...
EBV-positive diffuse large B-cell lymphoma of the elderly is an aggressive post-germinal center B-cell neoplasm characterized by prominent nuclear factor-kB activationSantiago Montes-Moreno
Pathology Department, Hospital Universitario Marques de Valdecilla, IFIMAV, Santander, Spain
Mod Pathol 25:968-82. 2012..Thus, alternative therapies, based on the tumor biology, need to be tested in patients with EBV-positive diffuse large B-cell lymphoma of the elderly...
Large B-cell lymphomas with plasmablastic differentiation: a biological and therapeutic challengeSantiago Montes-Moreno
Oncology Department, Hospital Ramon y Cajal, Madrid, Spain
Leuk Lymphoma 53:185-94. 2012....
Gcet1 (centerin), a highly restricted marker for a subset of germinal center-derived lymphomasSantiago Montes-Moreno
Lymphoma Group, Spanish National Cancer Centre CNIO, Madrid, Spain
Blood 111:351-8. 2008..The results of RNA and protein expression should prompt further investigation into the role of Gcet1 in regulating B-cell survival...
Aggressive large B-cell lymphoma with plasma cell differentiation: immunohistochemical characterization of plasmablastic lymphoma and diffuse large B-cell lymphoma with partial plasmablastic phenotypeSantiago Montes-Moreno
Lymphoma Group, Molecular Pathology Programme Spanish National Cancer Research Centre, CNIO, Madrid, Spain
Haematologica 95:1342-9. 2010..Plasmablastic lymphoma has recently come to be considered a distinct entity among mature B cell neoplasms, although the limits with diffuse large B-cell lymphoma (DLBCL) need to be more accurately defined...
Splenic diffuse red pulp small B-cell lymphoma: revision of a series of cases reveals characteristic clinico-pathological featuresGeorge Kanellis
Spanish National Cancer Research Centre CNIO, Madrid, Spain
Haematologica 95:1122-9. 2010..Additional work is required to review this entity and establish its diagnostic features...
miRNA expression in diffuse large B-cell lymphoma treated with chemoimmunotherapySantiago Montes-Moreno
Lymphoma Group, Spanish National Cancer Research Centre CNIO, Madrid, Spain
Blood 118:1034-40. 2011..This information improves upon IPI-based predictions and identifies a subgroup of candidate patients for alternative therapeutic regimens...
PRDM1/BLIMP-1 expression in multiple B and T-cell lymphomaJose Francisco Garcia
Monoclonal Antibodies Unit, Biotechnology Program, Spanish National Cancer Centre CNIO, Madrid, Spain
Haematologica 91:467-74. 2006..The positive regulatory domain I (PRDM1) protein or BLIMP-1, belonging to the PRDM gene family of transcriptional repressors, is a key regulator of terminal differentiation in B-lymphocytes and is critical for plasma cell differentiation...
Peripheral T-cell lymphoma with follicular T-cell markersSocorro Maria Rodriguez-Pinilla
Lymphoma Group, Molecular Pathology Programme, Spanish National Cancer Research Centre CNIO, Madrid, Spain
Am J Surg Pathol 32:1787-99. 2008..The aim of this study was to establish whether other PTCL subgroups also express TFH cell markers...
PD-1, a follicular T-cell marker useful for recognizing nodular lymphocyte-predominant Hodgkin lymphomaSyong H Nam-Cha
Lymphoma Group, Molecular Pathology Programme, Spanish National Cancer Centre CNIO, Madrid, Spain
Am J Surg Pathol 32:1252-7. 2008..The standard T/HRBCL cases lack follicular T-cell rosettes, whereas most of the borderline cases between the 2 entities have follicular T-cell rosettes, thus suggesting a closer relation with NLPHL...
The role of miRNAs in the pathogenesis and diagnosis of B-cell lymphomasLorena Di Lisio
Hospital Universitario Marqués de Valdecilla HUMV Instituto de Formación e Investigación Marqués de Valdecilla IFIMAV, Santander, Spain
Blood 120:1782-90. 2012..They identify miRNAs that could be used for diagnosis, prognosis, or prediction of response to specific therapies...
Epstein-Barr virus-positive systemic NK/T-cell lymphomas in children: report of six casesSocorro M Rodriguez-Pinilla
Lymphoma Group, Molecular Pathology Programme, Spanish National Cancer Research Centre CNIO, Madrid, Spain
Histopathology 59:1183-93. 2011..The aim of this study was to characterize six cases of paediatric EBV-positive peripheral T-cell lymphoma with distinct features...
Immunohistochemical analysis of HLDA9 Workshop antibodies against cell-surface molecules in reactive and neoplastic lymphoid tissuesRocio Ramos-Medina
Monoclonal Antibodies Unit, Biotechnology Programme, Spanish National Cancer Research Centre, Madrid, Spain
Immunol Lett 134:150-6. 2011....
EBV-associated cutaneous NK/T-cell lymphoma: review of a series of 14 cases from peru in children and young adultsSocorro Maria Rodriguez-Pinilla
Lymphoma Group, Molecular Pathology Programme, Spanish National Cancer Research Centre, CNIO, Madrid, Spain
Am J Surg Pathol 34:1773-82. 2010....
TCR-γ expression in primary cutaneous T-cell lymphomasSocorro Maria Rodriguez-Pinilla
CNIO Lymphoma Group, Fundacion Jimenez Diaz, Madrid, Spain
Am J Surg Pathol 37:375-84. 2013..Moreover, its expression does not seem to be associated with bad prognosis by itself, as it can be found in cases with good and bad outcomes...
Primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma expresses follicular T-cell markersSocorro Maria Rodriguez Pinilla
Lymphoma Group, Molecular Pathology Programme, Monoclonal Antibody Unit, Biotechnology Programme, Spanish National Cancer Research Centre, Hospital Universitario 12 de Octubre, Madrid, Spain
Am J Surg Pathol 33:81-90. 2009..Moreover, these findings suggest that B-cell stimulation by FTH could also take place in some cutaneous T-cell lymphomas...
TCL1A expression delineates biological and clinical variability in B-cell lymphomaMohit Aggarwal
Molecular Pathology Programme, Spanish National Cancer Research Centre CNIO, Madrid, Spain
Mod Pathol 22:206-15. 2009....
Expression pattern of XBP1(S) in human B-cell lymphomasLorena Maestre
Monoclonal Antibodies Unit, Biotechnology Program, Spanish National Cancer Centre CNIO, Madrid, Spain
Haematologica 94:419-22. 2009..Furthermore, our results establish a direct and practical means of assessing ER stress in human tumors...
Combinatorial effects of microRNAs to suppress the Myc oncogenic pathwayMaría J Bueno
Cell Division and Cancer Group, Centro Nacional de Investigaciones Oncologicas, Madrid, Spain
Blood 117:6255-66. 2011..Some of these Myc-targeting miRNAs are repressed by Myc, suggesting that these tumors are a consequence of the unbalanced activity of Myc versus miRNAs...
Splenic follicular lymphoma: clinicopathologic characteristics of a series of 32 casesManuela Mollejo
Pathology Department, Hospital Virgen de la Salud, Toledo, Spain
Am J Surg Pathol 33:730-8. 2009..Recognition of the distinct nature of these tumors should facilitate appropriate studies for determining the best therapy for such cases...
MicroRNAs as prognostic markers in indolent primary cutaneous B-cell lymphomaVeronica Monsálvez
Department of Dermatology, Hospital Universitario 12 de Octubre, Madrid, Spain
Mod Pathol 26:171-81. 2013..05). In summary, miRNA expression analysis can be used as a tool for diagnosis and outcome prognosis in indolent primary cutaneous B-cell lymphoma...
Cyclooxygenase-2 expression in bladder cancer and patient prognosis: results from a large clinical cohort and meta-analysisMaciej J Czachorowski
Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Centre CNIO, Madrid, Spain
PLoS ONE 7:e45025. 2012..The meta-analysis confirmed these results. We did not find evidence that COX2 expression is an independent prognostic marker of recurrence, progression or survival in patients with UCB...
Cherubism associated with neurofibromatosis type 1, and multiple osteolytic lesions of both femurs: a previously undescribed association of findingsFrancisco J Martinez-Tello
Departamento de Anatomia Patologica, Hospital Universitario 12 de Octubre, Carretera de Andalucía Km 5400, 28041, Madrid, Spain
Skeletal Radiol 34:793-8. 2005..We have been unable to find a similar case in the world literature. We discuss our findings in relationship with a number of syndromes that present clinical, radiological or pathological similarities...
