Oscar Miro

Summary

Country: Spain

Publications

  1. ncbi request reprint [Impact in the quality of health care and cost-effectiveness analysis of the reform of an emergency medicine service]
    - Miró O
    Unidad de Urgencias de Medicina Servicio de Urgencias Hospital Clínic Barcelona
    Med Clin (Barc) 117:7-11. 2001
  2. ncbi request reprint Muscle diseases in elders: a 10-year retrospective study
    Montserrat Laguno
    Muscle Research Unit, Department of Internal Medicine, August Pi i Sunyer Biomedical Research Institute IDIBAPS, Hospital Clinic, University of Barcelona, Catalonia, Spain
    J Gerontol A Biol Sci Med Sci 57:M378-84. 2002
  3. ncbi request reprint [Emergency department overcrowding: quantification of associated factors]
    Miquel Sanchez
    Unitat d Urgències de Medicina Servei d Urgències Hospital Clínic Barcelona España
    Med Clin (Barc) 121:161-72. 2003
  4. pmc Quality and effectiveness of an emergency department during weekends
    O Miro
    Emergency Department, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Emerg Med J 21:573-4. 2004
  5. ncbi request reprint [Treatment of symptomatic hyperlactatemia and lactic acidosis in HIV+ patients under nucleoside reverse transcriptase inhibitors]
    Enric Pedrol
    Departamento de Bioquimica, Fundació Hospital Asil de Granollers, Observatori Sanitari Dr Carles Vallbona OSVA, Granollers, Barcelona, Spain
    Med Clin (Barc) 125:201-4. 2005
  6. doi request reprint Multicentric investigation of survival after Spanish emergency department discharge for acute heart failure
    Oscar Miro
    Emergency Department, Area de Urgencias, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Eur J Emerg Med 19:153-60. 2012
  7. doi request reprint Research in emergency medicine in Europe
    O Scar Miró
    Department of Emergency, Hospital Clinic, Emergency Medicine Processes and Diseases, IDIBAPS, Barcelona, Catalonia, Spain
    Eur J Emerg Med 19:63-8. 2012
  8. pmc Undisclosed cocaine use and chest pain in emergency departments of Spain
    Guillermo Burillo-Putze
    Emergency Department, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Tenerife, Spain
    Scand J Trauma Resusc Emerg Med 17:11. 2009
  9. pmc State of emergency medicine in Spain
    Oscar Miro
    Emergency Department, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia Spain
    Int J Emerg Med 3:219-26. 2010
  10. ncbi request reprint [Direct discharge from triage in emergency departments: assessment, risks and patient satisfaction]
    Oscar Miro
    Unidad de Urgencias de Medicina, Hospital Clinic, Barcelona, Spain
    Med Clin (Barc) 126:88-93. 2006

Detail Information

Publications91

  1. ncbi request reprint [Impact in the quality of health care and cost-effectiveness analysis of the reform of an emergency medicine service]
    - Miró O
    Unidad de Urgencias de Medicina Servicio de Urgencias Hospital Clínic Barcelona
    Med Clin (Barc) 117:7-11. 2001
    ..To determine the effects that the reform of an emergency department (ED) have on efficacy, health care quality and efficiency...
  2. ncbi request reprint Muscle diseases in elders: a 10-year retrospective study
    Montserrat Laguno
    Muscle Research Unit, Department of Internal Medicine, August Pi i Sunyer Biomedical Research Institute IDIBAPS, Hospital Clinic, University of Barcelona, Catalonia, Spain
    J Gerontol A Biol Sci Med Sci 57:M378-84. 2002
    ..Muscle complaints are frequent among older adults, but histological data in this setting are scarce. Our objective was to detect the major categories of muscle diseases in the elderly population based on histological study...
  3. ncbi request reprint [Emergency department overcrowding: quantification of associated factors]
    Miquel Sanchez
    Unitat d Urgències de Medicina Servei d Urgències Hospital Clínic Barcelona España
    Med Clin (Barc) 121:161-72. 2003
    ..Emergency department (ED) overcrowding has been increasing over the last years. The aims are to define ED overcrowding, and to determine and quantify which factors explain it...
  4. pmc Quality and effectiveness of an emergency department during weekends
    O Miro
    Emergency Department, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Emerg Med J 21:573-4. 2004
    ..To evaluate whether the quality and effectiveness of an emergency department (ED) are modified during weekends...
  5. ncbi request reprint [Treatment of symptomatic hyperlactatemia and lactic acidosis in HIV+ patients under nucleoside reverse transcriptase inhibitors]
    Enric Pedrol
    Departamento de Bioquimica, Fundació Hospital Asil de Granollers, Observatori Sanitari Dr Carles Vallbona OSVA, Granollers, Barcelona, Spain
    Med Clin (Barc) 125:201-4. 2005
    ..We intended to find out the effectiveness of lactic acidosis therapy for mitochondrial toxicity...
  6. doi request reprint Multicentric investigation of survival after Spanish emergency department discharge for acute heart failure
    Oscar Miro
    Emergency Department, Area de Urgencias, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Eur J Emerg Med 19:153-60. 2012
    ..We have ascertained this hypothesis in patients with acute heart failure (AHF) directly discharged from EDs, analyzing their short-term outcome...
  7. doi request reprint Research in emergency medicine in Europe
    O Scar Miró
    Department of Emergency, Hospital Clinic, Emergency Medicine Processes and Diseases, IDIBAPS, Barcelona, Catalonia, Spain
    Eur J Emerg Med 19:63-8. 2012
    ..This study reviews these aspects and offers a personal perspective on where European EM research should be going...
  8. pmc Undisclosed cocaine use and chest pain in emergency departments of Spain
    Guillermo Burillo-Putze
    Emergency Department, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Tenerife, Spain
    Scand J Trauma Resusc Emerg Med 17:11. 2009
    ..Illicit cocaine consumption in Spain is one of the highest in Europe. Our objective was to study the incidence of undisclosed cocaine consumption in patients attending in two Spanish Emergency Departments for chest pain...
  9. pmc State of emergency medicine in Spain
    Oscar Miro
    Emergency Department, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia Spain
    Int J Emerg Med 3:219-26. 2010
    ..Spanish emergency physicians look forward to the final approval, which will complete the modernization of emergency health care provision in Spain...
  10. ncbi request reprint [Direct discharge from triage in emergency departments: assessment, risks and patient satisfaction]
    Oscar Miro
    Unidad de Urgencias de Medicina, Hospital Clinic, Barcelona, Spain
    Med Clin (Barc) 126:88-93. 2006
    ..The potential for 2 different referral models introduced in 2 urban hospitals was assessed, as well as the suitability of this measure...
  11. ncbi request reprint In vivo effects of highly active antiretroviral therapies containing the protease inhibitor nelfinavir on mitochondrially driven apoptosis
    Oscar Miro
    Mitochondrial Research Laboratory, Hospital Clinic, IDIBAPS, Barcelona, Catalonia, Spain
    Antivir Ther 10:945-51. 2005
    ....
  12. ncbi request reprint Mitochondrial studies in HAART-related lipodystrophy: from experimental hypothesis to clinical findings
    Oscar Miro
    Mitochondrial Research Laboratory, Department of Internal Medicine, Hospital Clinic, IDIBAPS, Barcelona, Catalonia, Spain
    Antivir Ther 10:M73-81. 2005
    ..Functional studies accompanying genetic investigations are needed for the correct pathogenic interpretation of the mtDNA abnormalities...
  13. ncbi request reprint Short communication: HIV infection, antiretrovirals, and apoptosis: studies on skeletal muscle
    Oscar Miro
    Mitochondrial Research Laboratory, Muscle Research Unit, Department of Internal Medicine, Hospital Clinic, IDIBAPS, Barcelona, Catalonia, Spain
    AIDS Res Hum Retroviruses 21:702-5. 2005
    ..We conclude that skeletal muscle of HIV-infected patients exhibits increased apoptosis compared with that of uninfected patients, but the role of HAART in inducing apoptosis remains to be established...
  14. ncbi request reprint [Basic cardiopulmonary resuscitation program for high school students (PROCES). Results from the pilot program]
    Oscar Miro
    Unidad de Urgencias Medicina, Hospital Clinic de Barcelona, Barcelona, Spain
    Med Clin (Barc) 124:4-9. 2005
    ..Our aim was to analyze the results obtained from the pilot program...
  15. ncbi request reprint Mitochondrial effects of HIV infection on the peripheral blood mononuclear cells of HIV-infected patients who were never treated with antiretrovirals
    Oscar Miro
    Mitochondrial Research Laboratory, Muscle Research Unit, Department of Internal Medicine, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Clin Infect Dis 39:710-6. 2004
    ..001), along with increased lipid peroxidation of PBMC membranes (P=.007). Therefore, HIV infection is associated not only with mtDNA depletion, but also with extensive MRC disturbances and increased oxidative damage...
  16. ncbi request reprint [Lack of inhospital beds: impact on emergency department performance]
    Oscar Miro
    Sección de Urgencias Medicina, Area de Urgencias, Hospital Clinic, Barcelona, Espana
    Med Clin (Barc) 126:736-9. 2006
    ..To determine the effect that the lack of inhospital beds exerts on emergency department performance...
  17. ncbi request reprint Teaching basic life support to 12-16 year olds in Barcelona schools: views of head teachers
    Oscar Miro
    Emergency Department, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Resuscitation 70:107-16. 2006
    ..To determine the opinion of head teachers on the educational and logistical characteristics required for a basic cardiopulmonary resuscitation (b-CPR) programme for secondary school teenagers to succeed...
  18. ncbi request reprint [Estimation of emergency department activity and its relationship with inhospital bed disposition]
    Oscar Miro
    Secció d Urgències de Medicina, Area d Urgències, Hospital Clinic, Barcelona, Espana
    Med Clin (Barc) 127:86-9. 2006
    ..To find out if the daily emergency department (ED) census and daily ED admittances can accurately be foreseen based on the number of visits arrived on ED within the first shift hours...
  19. ncbi request reprint Short communication metabolic and mitochondrial effects of switching antiretroviral-experienced patients to enfuvirtide, tenofovir and saquinavir/ritonavir
    Oscar Miro
    Mitochondrial Research Laboratory, Department of Internal Medicine, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain
    Antivir Ther 11:625-30. 2006
    ..Investigate the metabolic and mitochondrial effects of switching a highly active antiretroviral therapy (HAART) regimen with a high mitochondrial toxicity profile to a HAART with a theoretically low mitochondrial toxicity...
  20. doi request reprint Female representation on emergency medicine editorial teams
    Oscar Miro
    Emergency Department, Hospital Clinic, Villarroel 170, Barcelona 08036, Catalonia, Spain
    Eur J Emerg Med 17:84-8. 2010
    ..To analyse the presence of women on the editorial teams of emergency medicine journals and the potential relationship between the pre-eminence of the journal and their presence...
  21. doi request reprint Predicting the risk of reattendance for acute heart failure patients discharged from Spanish Emergency Department observation units
    Oscar Miro
    Emergency Department, Hospital Clinic, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Eur J Emerg Med 17:197-202. 2010
    ..We examined direct discharge rates from the ED OU, risk factors for returning to the ED, and returning and mortality rates...
  22. ncbi request reprint [Research in urgent and emergency medicine]
    Oscar Miro
    Area de Urgencias, Hospital Cínic, Barcelona 08036, Spain
    An Sist Sanit Navar 33:215-27. 2010
    ....
  23. ncbi request reprint [Where are we going? Emergency care 2030]
    Oscar Miro
    Area de Urgencias, Hospital Clinic, Barcelona 08036, Spain
    An Sist Sanit Navar 33:229-35. 2010
    ..8.The consolidation of an efficient and analytical accident and emergency medical practice. 9.The everyday character of information transfer as a sign of the new millennium. 10.The profession of emergency as a cause for pride...
  24. ncbi request reprint Skeletal muscle mitochondrial function is preserved in young patients with chronic renal failure
    Oscar Miro
    Department of Internal Medicine, Muscle Research Unit, Hospital Clinic, August Pi i Sunyer Biomedical Research Institute, University of Barcelona, Catalonia, Spain
    Am J Kidney Dis 39:1025-31. 2002
    ..We therefore conclude that mitochondrial function is preserved in young patients with CRF...
  25. ncbi request reprint [Quality assessment in Emergency Department: behavior respect to attendance demand]
    O Miro
    Servicio de Urgencias Hospital Clínic Barcelona
    Med Clin (Barc) 116:92-7. 2001
    ..We sought to evaluate whether the quality markers used to assess the outcomes of emergency care are modified by emergency department (ED) overcrowding...
  26. ncbi request reprint [Relative effects of external and internal factors on emergency department efficiency]
    O Miro
    Servicio de Urgencias Hospital Clínic Barcelona
    Med Clin (Barc) 115:294-6. 2000
    ..To know the relative effect of external and internal factors on emergency department (ED) efficiency...
  27. ncbi request reprint Heart mitochondrial respiratory chain complexes are functionally unaffected in heavy ethanol drinkers without cardiomyopathy
    O Miro
    Department of Internal Medicine, Hospital Clinic, August Pi i Sunyer Biomedical Research Institute, Medical School, University of Barcelona, Catalonia, Spain
    Alcohol Clin Exp Res 24:859-64. 2000
    ..We assessed individual enzyme activity of mitochondrial respiratory chain (MRC) complexes and membrane oxidative damage of heart mitochondria in active ethanol drinkers before the development of dilated cardiomyopathy...
  28. ncbi request reprint Trends in illicit drug emergencies: the emerging role of gamma-hydroxybutyrate
    Oscar Miro
    Emergency Department, Hospital Clinic, Barcelona, Spain
    J Toxicol Clin Toxicol 40:129-35. 2002
    ..Not surprisingly, an increasing number of acute overdose cases requiring emergency medical care have been reported and described, especially in the United States...
  29. pmc Analysis of patient flow in the emergency department and the effect of an extensive reorganisation
    O Miro
    Emergency Department, Hospital Clinic Barcelona, Villaroel 170, 08036 Barcelona, Catalonia, Spain
    Emerg Med J 20:143-8; discussion 148. 2003
    ..To evaluate the different internal factors influencing patient flow, effectiveness, and overcrowding in the emergency department (ED), as well as the effects of ED reorganisation on these indicators...
  30. ncbi request reprint Mitochondrial DNA depletion and respiratory chain enzyme deficiencies are present in peripheral blood mononuclear cells of HIV-infected patients with HAART-related lipodystrophy
    Oscar Miro
    Mitochondrial Research Lab, Muscle Research Unit, Dept of Internal Medicine, IDIBAPS, School of Medicine, Univ of Barcelona, Spain
    Antivir Ther 8:333-8. 2003
    ..Presented in 'Late Breakers and Hot Topics' session at 6th International Congress on Drug Therapy in HIV Infection, Glasgow, UK, 17-21 November 2002...
  31. ncbi request reprint Short communication: reversible mitochondrial respiratory chain impairment during symptomatic hyperlactatemia associated with antiretroviral therapy
    Oscar Miro
    Mitochondrial Research Laboratory, Department of Internal Medicine, Hospital Clinic, August Pi i Sunyer Biomedical Research Institute IDIBAPS, School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain
    AIDS Res Hum Retroviruses 19:1027-32. 2003
    ..Mitochondrial abnormalities had almost disappeared later when the patient became asymptomatic. Our findings support the hypothesis that MRC dysfunction stands at the basis of HAART-related hyperlactatemia...
  32. ncbi request reprint Upregulatory mechanisms compensate for mitochondrial DNA depletion in asymptomatic individuals receiving stavudine plus didanosine
    Oscar Miro
    Mitochondrial Research Laboratory, Muscle Research Unit, Department of Internal Medicine, Hospital Clinic, Institut d Investigations Bioiuèdiques August Pi I Sunyer, Barcelona, Spain
    J Acquir Immune Defic Syndr 37:1550-5. 2004
    ..These data suggest that upregulatory transcriptional or posttranscriptional mechanisms compensate for mtDNA depletion caused by d4T + ddI before profound mtDNA depletion occurs...
  33. ncbi request reprint [Ex vivo analysis of mitochondrial function in patients attended in an emergency department due to carbon monoxide poisoning]
    Oscar Miro
    Unidad de Urgencias Medicina Laboratorio de Funcionalismo Mitocondrial Grupo de Investigación Muscular Servicio de Medicina Interna Hospital Clínic de Barcelona Barcelona España
    Med Clin (Barc) 122:401-6. 2004
    ..The objective of this study was to evaluate from different points of view whether or not mitochondrial function is abnormal in patients admitted because of an acute CO poisoning...
  34. ncbi request reprint Longitudinal study on mitochondrial effects of didanosine-tenofovir combination
    Sonia Lopez
    Mitochondrial Research Laboratory, Muscle Research Unit, Internal Medicine Department, Hospital Clinic of Barcelona, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain
    AIDS Res Hum Retroviruses 22:33-9. 2006
    ..The particular relevance of either ddI, TDF, or any interaction between them in such a mitochondrial dysfunction remains to be established...
  35. ncbi request reprint Mitochondrial effects of antiretroviral therapies in asymptomatic patients
    Sonia Lopez
    Muscle Research Unit, Department of Internal Medicine, Hospital Clinic, August Pi i Sunyer Biomedical Research Institute IDIBAPS, School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain
    Antivir Ther 9:47-55. 2004
    ..A decrease in the mitochondrial (mt) DNA to nuclear DNA ratio has gained acceptance as a marker of mitochondrial toxicity in treated HIV-infected patients, but the functional meaning of this alteration is unclear...
  36. doi request reprint Improvement of mitochondrial toxicity in patients receiving a nucleoside reverse-transcriptase inhibitor-sparing strategy: results from the Multicenter Study with Nevirapine and Kaletra (MULTINEKA)
    Eugenia Negredo
    Lluita contra la SIDA Foundation, Barcelona, Spain
    Clin Infect Dis 49:892-900. 2009
    ..This study aimed to evaluate in vivo the effects of NRTI withdrawal on mitochondrial parameters and body fat distribution...
  37. doi request reprint Mitochondrial evolution in HIV-infected children receiving first- or second-generation nucleoside analogues
    Constanza Moren
    Mitochondrial Research Laboratory, Internal Medicine Department, Hospital Clinic of Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    J Acquir Immune Defic Syndr 60:111-6. 2012
    ..We aimed to study the evolution of mitochondrial parameters over time in children receiving different types antiretroviral regimens...
  38. doi request reprint Genetic and functional mitochondrial assessment of HIV-infected patients developing HAART-related hyperlactatemia
    Gloria Garrabou
    Mitochondrial Research Laboratory, Internal Medicine Department, Hospital Clinic of Barcelona, IDIBAPS, University of Barcelona and CIBER de Enfermedades Raras, CIBERER, Barcelona, Spain
    J Acquir Immune Defic Syndr 52:443-51. 2009
    ....
  39. doi request reprint Study of oxidative, enzymatic mitochondrial respiratory chain function and apoptosis in perinatally HIV-infected pediatric patients
    Constanza Moren
    Mitochondrial Functionalism Laboratory, University of Barcelona, IDIBAPS, Hospital Clinic of Barcelona, Barcelona, Spain
    Drug Chem Toxicol 36:496-500. 2013
    ..Mitochondrial impairment associated with HIV and HAART was generalized, rather than localized, in this series of perinatally HIV-infected patients...
  40. ncbi request reprint Mitochondrial effects of a 24-week course of pegylated-interferon plus ribavirin in asymptomatic HCV/HIV co-infected patients on long-term treatment with didanosine, stavudine or both
    Angel Luis Ballesteros
    HIV Clinical Unit, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Barcelona, Spain
    Antivir Ther 9:969-77. 2004
    ....
  41. doi request reprint Mitochondrial impact of human immunodeficiency virus and antiretrovirals on infected pediatric patients with or without lipodystrophy
    Constanza Moren
    Mitochondrial Functionalism Laboratory, University of Barcelona, IDIBAPS, Hospital Clinic of Barcelona, Barcelona, Spain
    Pediatr Infect Dis J 30:992-5. 2011
    ..Genetic, translational, and functional mitochondrial values were measured. As compared with controls, mitochondrial DNA depletion and a reduction in functionality were found in BFA groups...
  42. ncbi request reprint Mitochondrial assessment in asymptomatic HIV-infected paediatric patients on HAART
    Constanza Moren
    Mitochondrial Functionalism Laboratory, Universitat de Barcelona, IDIBAPS, Hospital Clinic, Barcelona, Spain
    Antivir Ther 16:719-24. 2011
    ..We aimed to determine whether mtDNA and mitochondrial function abnormalities are present in peripheral blood mononuclear cells from asymptomatic HIV-infected children...
  43. ncbi request reprint Partial immunological and mitochondrial recovery after reducing didanosine doses in patients on didanosine and tenofovir-based regimens
    Eugenia Negredo
    Germans Trias i Pujol University Hospital, Lluita contra la SIDA and IrsiCaixa Foundations, University of Barcelona, 08916 Badalona, Barcelona, Spain
    Antivir Ther 13:231-40. 2008
    ..We assessed whether a simple reduction of the ddl dose in patients receiving ddl (400 mg/day) and TDF could revert this side effect...
  44. ncbi request reprint [Failure of a special winter programme aimed to alleviate negative effects of winter overload on an emergency department]
    Emilio Salgado
    Sección de Urgencias de Medicina, Area de Urgencias, Hospital Clinic, Barcelona, Espana
    Med Clin (Barc) 130:286-91. 2008
    ....
  45. ncbi request reprint The impact of reducing stavudine dose versus switching to tenofovir on plasma lipids, body composition and mitochondrial function in HIV-infected patients
    Ana Milinkovic
    Infectious Diseases Unit, Hospital Clinic Barcelona, Barcelona, Spain
    Antivir Ther 12:407-15. 2007
    ..We assessed the safety and efficacy of reducing the dose of stavudine compared with switching to tenofovir or maintaining the standard dose of d4T...
  46. doi request reprint [Influence of patient's sex in the form of presentation and the management of acute heart failure in Spanish emergency rooms]
    Alba Riesgo
    Area de Urgencias, Hospital Clinic, Grupo de Investigación Urgencias procesos y patologías, IDIBAPS, Barcelona, Espana
    Med Clin (Barc) 134:671-7. 2010
    ..To evaluate the differences by sex in clinic presentation, diagnostic approach and initial treatment in patients with acute heart failure who are attended in emergency rooms...
  47. ncbi request reprint Triage flowchart to rule out acute coronary syndrome
    Miquel Sanchez
    Medicine Section, Emergency Department, Hospital Clinic, University of Barcelona, Catalonia, 08036 Barcelona, Spain
    Am J Emerg Med 25:865-72. 2007
    ..The aim of the study was to establish a triage flowchart to rule out acute coronary syndrome (ACS) among patients with chest pain (CP) arriving on an Emergency Department (ED)...
  48. doi request reprint Predictors and outcomes of frequent chest pain unit users
    Miquel Sanchez
    Secció d Urgències Medicina, Area d Urgències, Hospital Clinic, Universitat de Barcelona, Barcelona, 08036 Catalonia, Spain
    Am J Emerg Med 27:660-7. 2009
    ..To determine predictors of frequent chest pain unit (CPU) users and to identify characteristics and outcomes of their CPU visits...
  49. ncbi request reprint Mild improvement in mitochondrial function after a 3-year antiretroviral treatment interruption despite persistent impairment of mitochondrial DNA content
    Eugenia Negredo
    Lluita contra la SIDA Foundation, Germans Trias i Pujol Hospital, Universitat Autonoma de Barcelona, Barcelona, Spain
    Curr HIV Res 8:379-85. 2010
    ..The ability of a prolonged antiretroviral treatment interruption to reverse mitochondrial toxicity was evaluated in a sub-study of TIBET, a prospective trial examining antiretroviral treatment interruption guided by CD4+ cell count...
  50. doi request reprint Validation of a triage flowchart to rule out acute coronary syndrome
    Beatriz Lopez
    Emergency Department, Hospital Clinic de Barcelona, Barcelona, Spain
    Emerg Med J 28:841-6. 2011
    ..To validate a triage flowchart to rule out acute coronary syndrome (ACS) in chest pain patients attending the emergency department (ED)...
  51. doi request reprint The effects of sepsis on mitochondria
    Gloria Garrabou
    Mitochondrial Research Laboratory, IDIBAPS, University of Barcelona, Internal Medicine Department, Hospital Clínic of Barcelona HCB, Barcelona and Centro de Investigación Biomédica en Red de Enfermedades Raras CIBERER, Valencia
    J Infect Dis 205:392-400. 2012
    ..However, mitochondrial role in sepsis severity remains unknown. We aimed to characterize mitochondrial function in sepsis, establish its origin and cellular consequences, and determine its correlation with clinical symptoms and outcome...
  52. ncbi request reprint [Emergency department activity during the 2003 summer heat wave]
    Olga Trejo
    Servicio de Urgencias de Medicina, Hospital Clinic de Barcelona, Instituto de Investigación Biomédica August Pi i Sunyer IDIBAPS, Barcelona, Spain
    Med Clin (Barc) 125:205-9. 2005
    ..Several thousands deaths were attributed to a heatwave during the summer of 2003 in Europe. The aim of this study was to analyze its consequences in an emergency department...
  53. ncbi request reprint Effect of smoking cessation on mitochondrial respiratory chain function
    Francesc Cardellach
    Mitochondrial Research Laboratory, Muscle Research Unit, Department of Internal Medicine, August Pi i Sunyer Biomedical Research Institute IDIBAPS, Hospital Clinic, School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain
    J Toxicol Clin Toxicol 41:223-8. 2003
    ..These mitochondrial abnormalities have been proposed to contribute to pathogenesis of diseases associated with tobacco consumption. We assessed MRC function in peripheral lymphocytes from heavy smokers after cessation in smoking habit...
  54. ncbi request reprint [Effect of the incorporation of a general practitioner on emergency department effectiveness]
    Sonia Jimenez
    Secció d Urgències Medicina, Area d Urgències, Hospital Clinic, IDIBAPS, Villaroel 170, 08036 Barcelona, Spain
    Med Clin (Barc) 125:132-7. 2005
    ..To know the effect that the presence of a general practitioner (GP) has on emergency department's effectiveness, efficiency and health care...
  55. ncbi request reprint Enzymatic diagnosis of oxidative phosphorylation defects on muscle biopsy: better on tissue homogenate or on a mitochondria-enriched suspension?
    Jordi Casademont
    Muscle Research Unit, Department of Internal Medicine, Hospital Clinic, August Pi i Sunyer Biomedical Research Institute IDIBAPS, School of Medicine, University of Barcelona 08036 Barcelona, Spain
    Med Sci Monit 10:CS49-53. 2004
    ..In this situation, the study of muscle homogenate, paradoxically, may better reflect what happens in vivo...
  56. ncbi request reprint Mitochondrial respiratory chain in brain homogenates: activities in different brain areas in patients with Alzheimer's disease
    Jordi Casademont
    Muscle Research Unit, Internal Medicine Department, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Aging Clin Exp Res 17:1-7. 2005
    ..We simultaneously assessed the lipid peroxidation of the samples as a measure of free radical damage...
  57. doi request reprint Knowledge about disease course and living wills among patients with heart failure
    Albert Antolín
    Area de Urgencias, Hospital Clinic, Grupo de Investigación Urgencias procesos y patologías, Fundació Clínic, Barcelona, Spain
    Rev Esp Cardiol (Engl Ed) 63:1410-8. 2010
    ..To determine the level of knowledge about possible disease outcomes and living wills among patients with heart failure (HF) treated in an emergency department and to evaluate their willingness to draw up a living will...
  58. doi request reprint Short-term Prognostic Factors in Elderly Patients Seen in Emergency Departments for Acute Heart Failure
    Oscar Miro
    Area de Urgencias, Hospital Clinic, Barcelona, Spain
    Rev Esp Cardiol (Engl Ed) 62:757-64. 2009
    ..To investigate factors associated with short-term mortality in elderly patients seen in emergency departments for an episode of acute heart failure...
  59. doi request reprint [Home hospitalization directly from emergency department: an efficient alternative to standard inpatient hospitalization]
    Sonia Jimenez
    Sección de Urgencias Medicina, Area de Urgencias, Hospital Clinic, Barcelona, Espana
    Med Clin (Barc) 137:587-90. 2011
    ..To compare technical quality, patient health outcomes, and satisfaction degree of patients admitted to hospital at home (HAH) from the emergency department (ED) with those with standard hospitalization (SH)...
  60. ncbi request reprint Transient endothelial dysfunction is present shortly after cardioversion in patients with lone atrial fibrillation
    Blanca Coll-Vinent
    Emergency Department, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Thromb Res 117:235-40. 2006
  61. doi request reprint Barthel Index-Enhanced Feedback for Effective Cardiac Treatment (BI-EFFECT) Study: contribution of the Barthel Index to the Heart Failure Risk Scoring System model in elderly adults with acute heart failure in the emergency department
    F Javier Martín-Sánchez
    Emergency Department, Hospital Clinico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain
    J Am Geriatr Soc 60:493-8. 2012
    ....
  62. doi request reprint Evolution of mitochondrial DNA content after planned interruption of HAART in HIV-infected pediatric patients
    Antoni Noguera
    Unitat d Infectologia, Servei de Pediatria, Hospital Sant Joan de Deu, University of Barcelona, Barcelona, Spain
    AIDS Res Hum Retroviruses 26:1015-8. 2010
    ..In this series, PTI led to a partial restoration of mtDNA levels and a significant decrease in lactate values...
  63. pmc Reversible inhibition of mitochondrial protein synthesis during linezolid-related hyperlactatemia
    Gloria Garrabou
    Mitochondrial Research Laboratory, Muscle Research Unit, Internal Medicine Department, Hospital Clinic of Barcelona, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Antimicrob Agents Chemother 51:962-7. 2007
    ..Linezolid inhibits mitochondrial protein synthesis, leading to decreased mitochondrial enzymatic activity, which causes linezolid-related hyperlactatemia, which resolves upon discontinuation of linezolid treatment...
  64. ncbi request reprint Neuroleptic treatment effect on mitochondrial electron transport chain: peripheral blood mononuclear cells analysis in psychotic patients
    Jordi Casademont
    Muscle Research Unit, Internal Medicine Department, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    J Clin Psychopharmacol 27:284-8. 2007
    ..It remains to be established if this finding in a nontarget tissue for antipsychotics may account for the lower incidence of movement disorders observed in patients on atypical agents...
  65. doi request reprint Management of acute atrial fibrillation in the emergency department: a systematic review of recent studies
    Blanca Coll-Vinent
    Emergency Area, Hospital Clinic, 08036 Barcelona, Spain
    Eur J Emerg Med 20:151-9. 2013
    ..Amiodarone had a longer conversion time, with a similar rate of acute adverse events. Cardioversion in the emergency department is feasible and safe. Direct current cardioversion is the most effective therapeutic strategy...
  66. ncbi request reprint Diagnosis of mitochondrial dysfunction in HIV-infected patients under highly active antiretroviral therapy: possibilities beyond the standard procedures
    Jordi Casademont
    Laboratory of Mitochondrial Function, Department of Internal Medicine, Hospital Clinic, IDIBAPS, Medical School, University of Barcelona, Barcelona, Catalonia, Spain
    Antivir Ther 10:M65-71. 2005
  67. doi request reprint Perinatal outcomes, mitochondrial toxicity and apoptosis in HIV-treated pregnant women and in-utero-exposed newborn
    Sandra Hernandez
    Materno Fetal Medicine Department, Clinical Institute of Gynaecology, Obstetrics and Neonatology, Barcelona, Spain
    AIDS 26:419-28. 2012
    ..We determined whether mitochondrial toxicity and apoptosis are present in HIV-pregnant women and their newborns and could be the basis of adverse pregnancy outcome...
  68. doi request reprint Multicenter assessment of the revisit risk for a further drug-related problem in the emergency department in cocaine users (MARRIED-cocaine study)
    Miguel Galicia
    Emergency Department, Hospital Clinic, Barcelona, Spain
    Clin Toxicol (Phila) 50:176-82. 2012
    ..After discharge, some of these patients revisit the ED for the same reason within a year. The objective of the present study was to quantify the rate of such revisits and identify the factors associated with them...
  69. doi request reprint [Psychosocial factors determine patients' acceptance of emergency department discharge directly to hospital-at-home care]
    Sonia Jimenez
    Sección de Urgencias Medicina, Area de Urgencias, Hospital Clinic, Barcelona, Espana
    Gac Sanit 24:303-8. 2010
    ..To identify the factors associated with patients' acceptance of emergency department discharge directly to hospital-at-home care...
  70. doi request reprint Mitochondrial damage in adipose tissue of untreated HIV-infected patients
    Gloria Garrabou
    Mitochondrial Research Laboratory, Internal Medicine Department, Muscle Research Unit, IDIBAPS, University of Barcelona, Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Raras, Spain
    AIDS 25:165-70. 2011
    ..However, the viral capacity to induce adipose tissue mitochondrial lesion is still a matter of doubt. We aimed to assess whether untreated HIV infection was associated with adipose tissue mitochondrial abnormalities...
  71. ncbi request reprint Mitochondrial DNA depletion in oocytes of HIV-infected antiretroviral-treated infertile women
    Sonia Lopez
    Mitochondrial Research Laboratory, Internal Medicine Department, IDIBAPS, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain
    Antivir Ther 13:833-8. 2008
    ..We hypothesized that mitochondrial toxicity caused by antiretrovirals could be the underlying mechanism of such disturbance...
  72. ncbi request reprint [Impact of implementing common guidelines at different care levels in a healthcare area on the improvement of atrial fibrillation treatment]
    Blanca Coll-Vinent
    Servicio de Urgencias, Hospital Clinic, Barcelona, Spain
    Rev Esp Cardiol 60:392-403. 2007
    ..The objective of the study was to analyze the impact of the implementation of a practice guideline about AF treatment common to the different levels of health attention on the adequacy of AF treatment and on corrective interventions...
  73. doi request reprint Results achieved by emergency physicians in teaching basic cardiopulmonary resuscitation to secondary school students
    Xavier Jiménez-Fábrega
    SEMSA, Barcelona, Spain
    Eur J Emerg Med 16:139-44. 2009
    ..We investigated the results obtained with a basic cardiopulmonary resuscitation (b-CPR) program (PROCES) specifically designed for secondary school students (14-16 years old) and taught by emergency physicians...
  74. doi request reprint Predicting bacteremic pneumonia in HIV-1-infected patients consulting the ED
    Rafael Perello
    Emergency Department, Hospital Clinic, Barcelona, Institut d Investigacions Biomèdiques Agustí Pi i Sunyer IDIBAPS, University of Barcelona 08036, Spain
    Am J Emerg Med 28:454-9. 2010
    ..Bacteremia has been associated with a higher risk of complications in such patients. We investigated factors associated with bacteremia in HIV-1-infected patients with CAP presenting at the emergency department...
  75. ncbi request reprint Short-term prognostic factors in elderly patients seen in emergency departments for acute heart failure
    Oscar Miro
    Area de Urgencias, Hospital Clinic, Barcelona, Espana
    Rev Esp Cardiol 62:757-64. 2009
    ..To investigate factors associated with short-term mortality in elderly patients seen in emergency departments for an episode of acute heart failure...
  76. ncbi request reprint [Factors associated with revisit and admission in patients complaining of fever that are discharged from the emergency department]
    Mar Ortega
    Sección de Urgencias Medicina, Area de Urgencias, Hospital Clinic, Barcelona, Espana
    Med Clin (Barc) 128:251-3. 2007
    ..To identify factors associated with both emergency department (ED) revisit, and hospital admission of patients complaining of fever that have previously been seen and discharged from the ED...
  77. doi request reprint Sex differences in the treatment of patients with atrial fibrillation: population-based study in a local health district
    Alba Riesgo
    Sección de Urgencias, Area de Urgencias, Hospital Clinic, Barcelona, Espana
    Rev Esp Cardiol 64:233-6. 2011
    ..In conclusion, gender differences observed in the treatment of atrial fibrillation cannot be fully explained by differences in clinical characteristics between men and women in the population...
  78. ncbi request reprint Lopinavir/ritonavir plus nevirapine as a nucleoside-sparing approach in antiretroviral-experienced patients (NEKA study)
    Eugenia Negredo
    Department of Internal Medicine, Lluita contra la SIDA and IrsiCaixa Foundations, Germans Trias i Pujol Hospital, Badalona, Universitat Autonoma de Barcelona, Barcelona, Spain
    J Acquir Immune Defic Syndr 38:47-52. 2005
    ..To compare the efficacy and safety of a nucleoside-sparing approach with a conventional highly active antiretroviral therapy (HAART) regimen in antiretroviral-experienced patients with prolonged viral suppression...
  79. ncbi request reprint Sedation for cardioversion in the emergency department: analysis of effectiveness in four protocols
    Blanca Coll-Vinent
    Emergency Department, Hospital Clinic, Barcelona, Spain
    Ann Emerg Med 42:767-72. 2003
    ..We compare effectiveness, adverse effects, and recovery times of propofol, etomidate, and midazolam (with and without flumazenil) for cardioversion in the emergency department (ED)...
  80. ncbi request reprint [Performance assessment of an emergency department chest pain unit]
    Ernest Bragulat
    Servicio de Urgencias, Area de Urgencias, Hospital Clinic, Barcelona, Spain
    Rev Esp Cardiol 60:276-84. 2007
    ....
  81. ncbi request reprint [Poisoning by liquid ecstasy (GHB) in hospital emergency departments of Barcelona: a 2-years study]
    Miguel Galicia
    Servicio de Urgencias, Hospital Clinic, Barcelona, Espana
    Med Clin (Barc) 130:254-8. 2008
    ..To describe the epidemiological profile and clinical manifestations, we analyzed cases of poisoning by GHB attended by the Emergency Departments (ED) of 2 hospitals of the city of Barcelona...
  82. ncbi request reprint [Adverse effects of antiarrhythmic drugs in patients with atrial fibrillation in primary care]
    Luisa Benito
    Grup transversal de recerca en Atenció Primària, IDIBAPS, Barcelona, Espana
    Med Clin (Barc) 137:241-6. 2011
    ..To determine the adverse effects (AE) of antiarrhythmic drugs used to treat atrial fibrillation (AF) in routine clinical practice...
  83. ncbi request reprint [Knowledge about disease course and living wills among patients with heart failure]
    Albert Antolín
    Area de Urgencias, Hospital Clinic, Grupo de Investigación Urgencias, Procesos y Patologías, Fundació Clínic, Barcelona, Espana
    Rev Esp Cardiol 63:1410-8. 2010
    ..To determine the level of knowledge about possible disease outcomes and living wills among patients with heart failure (HF) treated in an emergency department and to evaluate their willingness to draw up a living will...
  84. doi request reprint Liquid ecstasy intoxication: clinical features of 505 consecutive emergency department patients
    Miguel Galicia
    Emergency Department, Hospital Clinic, Calle Villarroel 170, 08036 Barcelona, Spain
    Emerg Med J 28:462-6. 2011
    ..To describe the epidemiological profile and clinical manifestations of liquid ecstasy (GHB) poisonings...
  85. ncbi request reprint [Treatment of atrial fibrillation at different levels of health care]
    Blanca Coll-Vinent
    Servicio de Urgencias, Hospital Clinic, Barcelona, Espana
    Med Clin (Barc) 128:125-9. 2007
    ..We sought to analyze treatment and compliance of the prevailing guidelines of patients with atrial fibrillation attended at different levels of health care and to quantify interventions to correct treatment inadequacies...
  86. ncbi request reprint Carbon monoxide specifically inhibits cytochrome c oxidase of human mitochondrial respiratory chain
    José Ramón Alonso
    Department of Internal Medicine, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain
    Pharmacol Toxicol 93:142-6. 2003
    ..This inhibition in cytochrome c oxidase may play a role in the development of the symptoms observed in acute CO poisoning, and in some diseases related to smoking...
  87. ncbi request reprint Electron transport chain defects in heart failure
    Jordi Casademont
    Muscle Research Unit, Department of Internal Medicine, Hospital Clinic, August Pi i Sunyer Biomedical Research Institute IDIBAPS, University of Barcelona, Catalonia, Spain
    Heart Fail Rev 7:131-9. 2002
    ..e. diastolic heart failure), as well as mitochondrial defects outside the electron transport chain (i.e., defects in Krebs cycle or beta-oxidation of fatty acids) are only approached circumstantially...
  88. ncbi request reprint [Analysis of patients attended in an emergency department due to ecstasy consumption]
    Eduard Sanjurjo
    Servicio de Urgencias, Hospital Clinic, Barcelona, Spain
    Med Clin (Barc) 123:90-2. 2004
    ..There has been in recent years an increase in the number of medical emergencies due to the consumption of designer drugs. We decided to study the characteristics of medical emergencies generated by the consumption of amphetamine derivates...
  89. doi request reprint [Chronically-ill patients in emergency care: degree of understanding and agreement with the person accompanying them regarding their possible clinical course]
    Albert Antolín
    Secció d Urgències Medicina, Area d Urgències, Hospital Clinic, Barcelona, Espana
    Med Clin (Barc) 132:501-4. 2009
    ..To determine the factors associated to patient's and companion's knowledge and the level of concordance among them...
  90. doi request reprint [Use of activated charcoal in acute poisonings: clinical safety and factors associated with adverse reactions in 575 cases]
    Montserrat Amigó
    Sección de Toxicología Clínica y Sección de Urgencias de Medicina, Servicio de Urgencias, Hospital Clinic, Barcelona, Espana
    Med Clin (Barc) 135:243-9. 2010
    ..To identify the pattern of use of activated charcoal in the treatment of poisonings, and to evaluate the prevalence and severity of adverse reactions and define the risk factors associated with them...
  91. ncbi request reprint [Forearm ischemic exercise test. Standardization and diagnostic value in the identification of McArdle disease]
    Eduard Sanjurjo
    Unidad de Investigación de Muscular, Servicio de Medicina Interna, Institut de Recerca Biomèdica August Pi i Sunyer IDIBAPS, Hospital Clinic, Universidad de Barcelona, Spain
    Med Clin (Barc) 122:761-6. 2004
    ..Yet there is no uniformity with regard to the intensity of the work and the ischemia time. The aim of this study was to standardize the test conditions in normal people and to check its efficacy in our population...