Juan A Mico

Summary

Country: Spain

Publications

  1. ncbi Elucidating the mechanism of action of pregabalin: α(2)δ as a therapeutic target in anxiety
    Juan Antonio Mico
    Department of Neuroscience, Pharmacology and Psychiatry, CIBER of Mental Health, CIBERSAM, Instituto de Salud Carlos III, University of Cdiz, Cdiz, Spain
    CNS Drugs 26:637-48. 2012
  2. ncbi Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression
    Icíar Gárate
    Department of Pharmacology, Faculty of Medicine, Universidad Complutense, Madrid 28040, Spain
    J Neuroinflammation 8:151. 2011
  3. ncbi Reduced antioxidant defense in early onset first-episode psychosis: a case-control study
    Juan Antonio Mico
    Department of Neuroscience, Pharmacology and Psychiatry, School of Medicine, CIBERSAM, Centro de Investigación Biomédica en Red de Salud Mental University of Cádiz, Spain
    BMC Psychiatry 11:26. 2011
  4. ncbi Medically unexplained pain complaints are associated with underlying unrecognized mood disorders in primary care
    Luis Aguera
    Preventive Medicine and Public Health Department, University of Cadiz, Spain
    BMC Fam Pract 11:17. 2010
  5. ncbi The role of 5-HT1A receptors in research strategy for extensive pain treatment
    Juan A Mico
    Department of Neuroscience, Pharmacology and Psychiatry, School of Medicine, University of Cadiz, Plaza Fragela 9, 11003 Cadiz, Spain
    Curr Top Med Chem 6:1997-2003. 2006
  6. ncbi Antidepressants and pain
    Juan A Mico
    Pharmacology and Neuroscience Research Group, Department of Neuroscience Pharmacology and Psychiatry, School of Medicine, University of Cadiz, Plaza Fragela 9, 11003 Cadiz, Spain
    Trends Pharmacol Sci 27:348-54. 2006
  7. ncbi Role of serotonin 5-HT1A and opioid receptors in the antiallodynic effect of tramadol in the chronic constriction injury model of neuropathic pain in rats
    Esther Berrocoso
    Pharmacology and Neuroscience Research Group, Department of Neuroscience Pharmacology and Psychiatry, School of Medicine, University of Cadiz, Plaza Falla 9, 11003, Cadiz, Spain
    Psychopharmacology (Berl) 193:97-105. 2007
  8. ncbi Differential role of 5-HT1A and 5-HT1B receptors on the antinociceptive and antidepressant effect of tramadol in mice
    Esther Berrocoso
    Pharmacology and Neuroscience Research Group, Department of Neuroscience (Pharmacology and Psychiatry, School of Medicine, , Plaza Falla 9, 11003, , Spain
    Psychopharmacology (Berl) 188:111-8. 2006
  9. ncbi Role of serotonin 5-HT1A receptors in the antidepressant-like effect and the antinociceptive effect of venlafaxine in mice
    Esther Berrocoso
    Pharmacology and Neuroscience Research Group, Department of Neuroscience Pharmacology and Psychiatry, School of Medicine, University of Cadiz, Cadiz, Spain
    Int J Neuropsychopharmacol 12:61-71. 2009
  10. ncbi Role of atypical opiates in OCD. Experimental approach through the study of 5-HT(2A/C) receptor-mediated behavior
    M Olga Rojas-Corrales
    Group of Research and Development in Neuropsychopharmacology, Department of Neuroscience, Faculty of Medicine, University of Cadiz, Plz Falla 9, 11003, Cadiz, Spain
    Psychopharmacology (Berl) 190:221-31. 2007

Collaborators

  • Javier Garzón
  • Esther Berrocoso
  • Pilar Sánchez-Blázquez
  • Jorge E Ortega
  • D Ardid
  • Antonio Ortega-Alvaro
  • Cristina Alba-Delgado
  • Juan C Leza
  • Icíar Gárate
  • Luis Aguera
  • M Olga Rojas-Corrales
  • Juan Gibert-Rahola
  • Aránzazu Roca-Vinardell
  • Fani Neto
  • Raquel Rey-Brea
  • J Javier Meana
  • Igor Horrillo
  • Gisela Borges
  • Jose L M Madrigal
  • Borja García-Bueno
  • Lidia Bravo
  • Javier R Caso
  • Inmaculada Failde
  • Jorge A Cervilla
  • Paula Díaz-Fernández

Detail Information

Publications14

  1. ncbi Elucidating the mechanism of action of pregabalin: α(2)δ as a therapeutic target in anxiety
    Juan Antonio Mico
    Department of Neuroscience, Pharmacology and Psychiatry, CIBER of Mental Health, CIBERSAM, Instituto de Salud Carlos III, University of Cdiz, Cdiz, Spain
    CNS Drugs 26:637-48. 2012
    ..Finally, pregabalin may also act by inhibiting synaptogenesis of excitatory neurons formed in response to chronic stress or anxiety, or more acutely inhibit the trafficking of CaV to the plasma membrane...
  2. ncbi Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression
    Icíar Gárate
    Department of Pharmacology, Faculty of Medicine, Universidad Complutense, Madrid 28040, Spain
    J Neuroinflammation 8:151. 2011
    ....
  3. ncbi Reduced antioxidant defense in early onset first-episode psychosis: a case-control study
    Juan Antonio Mico
    Department of Neuroscience, Pharmacology and Psychiatry, School of Medicine, CIBERSAM, Centro de Investigación Biomédica en Red de Salud Mental University of Cádiz, Spain
    BMC Psychiatry 11:26. 2011
    ..Our objective is to determine the activity of the antioxidant defense system at admission in patients with early onset first psychotic episodes compared with a control group...
  4. ncbi Medically unexplained pain complaints are associated with underlying unrecognized mood disorders in primary care
    Luis Aguera
    Preventive Medicine and Public Health Department, University of Cadiz, Spain
    BMC Fam Pract 11:17. 2010
    ..Also, to compare the use of health services by patients with unexplained chronic pain, both with and without mood disorder comorbidity...
  5. ncbi The role of 5-HT1A receptors in research strategy for extensive pain treatment
    Juan A Mico
    Department of Neuroscience, Pharmacology and Psychiatry, School of Medicine, University of Cadiz, Plaza Fragela 9, 11003 Cadiz, Spain
    Curr Top Med Chem 6:1997-2003. 2006
    ..Therefore, 5-HT1A receptors may be used as a new target in the search for new pharmacological approaches in the augmentation of analgesia...
  6. ncbi Antidepressants and pain
    Juan A Mico
    Pharmacology and Neuroscience Research Group, Department of Neuroscience Pharmacology and Psychiatry, School of Medicine, University of Cadiz, Plaza Fragela 9, 11003 Cadiz, Spain
    Trends Pharmacol Sci 27:348-54. 2006
    ..We suggest that antidepressants have a genuine analgesic effect and that research into their mechanisms of action will help to facilitate the development of new drugs...
  7. ncbi Role of serotonin 5-HT1A and opioid receptors in the antiallodynic effect of tramadol in the chronic constriction injury model of neuropathic pain in rats
    Esther Berrocoso
    Pharmacology and Neuroscience Research Group, Department of Neuroscience Pharmacology and Psychiatry, School of Medicine, University of Cadiz, Plaza Falla 9, 11003, Cadiz, Spain
    Psychopharmacology (Berl) 193:97-105. 2007
    ....
  8. ncbi Differential role of 5-HT1A and 5-HT1B receptors on the antinociceptive and antidepressant effect of tramadol in mice
    Esther Berrocoso
    Pharmacology and Neuroscience Research Group, Department of Neuroscience (Pharmacology and Psychiatry, School of Medicine, , Plaza Falla 9, 11003, , Spain
    Psychopharmacology (Berl) 188:111-8. 2006
    ..In contrast, the 5-HT1A receptors located in the forebrain may be responsible for the blockade of the antidepressant-like effect of tramadol. 5-HT1B receptors seem not to modify these effects in the models investigated...
  9. ncbi Role of serotonin 5-HT1A receptors in the antidepressant-like effect and the antinociceptive effect of venlafaxine in mice
    Esther Berrocoso
    Pharmacology and Neuroscience Research Group, Department of Neuroscience Pharmacology and Psychiatry, School of Medicine, University of Cadiz, Cadiz, Spain
    Int J Neuropsychopharmacol 12:61-71. 2009
    ..In contrast, the antinociceptive effect of venlafaxine is probably potentiated due to the blockade of somatodendritic 5-HT1A receptors in the same raphe nuclei, facilitating the descending monoaminergic pain control system...
  10. ncbi Role of atypical opiates in OCD. Experimental approach through the study of 5-HT(2A/C) receptor-mediated behavior
    M Olga Rojas-Corrales
    Group of Research and Development in Neuropsychopharmacology, Department of Neuroscience, Faculty of Medicine, University of Cadiz, Plz Falla 9, 11003, Cadiz, Spain
    Psychopharmacology (Berl) 190:221-31. 2007
    ..Opiate drugs are also effective in treatment-refractory OCD and Tourette syndrome. The 5-HT2A-related behavior (i.e., head twitch) has been related with tics, stereotypes, and compulsive symptoms observed in Tourette syndrome and OCD...
  11. ncbi The role of 5-HT1A/B autoreceptors in the antinociceptive effect of systemic administration of acetaminophen
    Aránzazu Roca-Vinardell
    Department of Neuroscience, Faculty of Medicine, University of Cadiz, Spain
    Anesthesiology 98:741-7. 2003
    ..This study examines the involvement of 5-HT(1A/B) receptors in the antinociceptive effect of acetaminophen in mice...
  12. ncbi Opiates as antidepressants
    Esther Berrocoso
    Pharmacology and Neuroscience Research Group, Department of Neuroscience Pharmacology and Psychiatry, School of Medicine, University of Cadiz, Plaza Fragela 9, Cadiz, Spain
    Curr Pharm Des 15:1612-22. 2009
    ..A compilation of the most significant studies will illustrate the actual and potential value of the opioid system for clinical research and drug development...
  13. ncbi The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain
    Cristina Alba-Delgado
    Neuropsychopharmacology Research Group, Department of Neuroscience, University of Cadiz, 11003 Cadiz, Spain
    Psychopharmacology (Berl) 221:53-65. 2012
    ..The noradrenergic locus coeruleus (LC) is a crucial component of ascending and descending pain pathways, both of which are frequently compromised after nerve injury...
  14. ncbi Comparison of the antinociceptive effects of ibuprofen arginate and ibuprofen in rat models of inflammatory and neuropathic pain
    Antonio Ortega-Alvaro
    Research and Development in Neuropsychopharmacology Group PAI CTS 510, Department of Neuroscience, Faculty of Medicine, University of Cadiz, Cadiz, Spain
    Life Sci 90:13-20. 2012
    ..This formulation is absorbed faster, and it is safe and effective in treating many forms of mild to moderate pain. We compared the analgesic effect of ibuprofen arginate and conventional ibuprofen in rat models of pain...