Lourdes Mengual

Summary

Country: Spain

Publications

  1. ncbi request reprint Gene expression profiles in prostate cancer: identification of candidate non-invasive diagnostic markers
    L Mengual
    Laboratorio y Servicio de Urología, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Barcelona, España Electronic address
    Actas Urol Esp 38:143-9. 2014
  2. doi request reprint Validation study of a noninvasive urine test for diagnosis and prognosis assessment of bladder cancer: evidence for improved models
    Lourdes Mengual
    Laboratory and Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain Electronic address
    J Urol 191:261-9. 2014
  3. ncbi request reprint [New concepts in molecular biology applied to traslational research]
    Lourdes Mengual
    Laboratorio y Servicio Urología, Hospital Clinico, Instituto de Investigaciones Biomédicas August Pi i Sunyer IDIBAPS y Unidad Genética, Departamento de Ciencias Fisiológicas I, Facultad de Medicina, Universidad de Barcelona, Barcelona, Espana
    Arch Esp Urol 66:401-8. 2013
  4. doi request reprint Gene expression signature in urine for diagnosing and assessing aggressiveness of bladder urothelial carcinoma
    Lourdes Mengual
    Laboratory and Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain
    Clin Cancer Res 16:2624-33. 2010
  5. doi request reprint Biomarkers vs conventional histological analysis to detect lymph node micrometastases in bladder cancer: a real improvement?
    Cristina Gazquez
    Laboratory and Department of Urology, Institut Clínic de Nefrologia i Urologia ICNU, Universitat de Barcelona, Barcelona, Spain
    BJU Int 110:1310-6. 2012
  6. ncbi request reprint Utility of a multiprobe fluorescence in situ hybridization assay in the detection of superficial urothelial bladder cancer
    Mercedes Marín-Aguilera
    Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Cancer Genet Cytogenet 173:131-5. 2007
  7. ncbi request reprint Clinical utility of fluorescent in situ hybridization for the surveillance of bladder cancer patients treated with bacillus Calmette-Guérin therapy
    Lourdes Mengual
    Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Universitat de Barcelona, Spain
    Eur Urol 52:752-9. 2007
  8. doi request reprint Molecular lymph node staging in bladder urothelial carcinoma: impact on survival
    Mercedes Marín-Aguilera
    Laboratory of Urology, Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Barcelona, Spain
    Eur Urol 54:1363-72. 2008
  9. doi request reprint Utility of urothelial mRNA markers in blood for staging and monitoring bladder cancer
    Mercedes Marín-Aguilera
    Laboratory and Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Urology 79:240.e9-15. 2012
  10. doi request reprint Using microRNA profiling in urine samples to develop a non-invasive test for bladder cancer
    Lourdes Mengual
    Laboratory and Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Spain
    Int J Cancer 133:2631-41. 2013

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Gene expression profiles in prostate cancer: identification of candidate non-invasive diagnostic markers
    L Mengual
    Laboratorio y Servicio de Urología, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Barcelona, España Electronic address
    Actas Urol Esp 38:143-9. 2014
    ....
  2. doi request reprint Validation study of a noninvasive urine test for diagnosis and prognosis assessment of bladder cancer: evidence for improved models
    Lourdes Mengual
    Laboratory and Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain Electronic address
    J Urol 191:261-9. 2014
    ..We validated the performance of our previously reported test for bladder cancer based on urine gene expression patterns using an independent cohort. We also ascertained whether alternative models could achieve better accuracy...
  3. ncbi request reprint [New concepts in molecular biology applied to traslational research]
    Lourdes Mengual
    Laboratorio y Servicio Urología, Hospital Clinico, Instituto de Investigaciones Biomédicas August Pi i Sunyer IDIBAPS y Unidad Genética, Departamento de Ciencias Fisiológicas I, Facultad de Medicina, Universidad de Barcelona, Barcelona, Espana
    Arch Esp Urol 66:401-8. 2013
    ..Moreover, we give examples of translational application of these new methodologies described. ..
  4. doi request reprint Gene expression signature in urine for diagnosing and assessing aggressiveness of bladder urothelial carcinoma
    Lourdes Mengual
    Laboratory and Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain
    Clin Cancer Res 16:2624-33. 2010
    ..To develop an accurate and noninvasive method for bladder cancer diagnosis and prediction of disease aggressiveness based on the gene expression patterns of urine samples...
  5. doi request reprint Biomarkers vs conventional histological analysis to detect lymph node micrometastases in bladder cancer: a real improvement?
    Cristina Gazquez
    Laboratory and Department of Urology, Institut Clínic de Nefrologia i Urologia ICNU, Universitat de Barcelona, Barcelona, Spain
    BJU Int 110:1310-6. 2012
    ..We concluded that molecular analysis of LN spreading in bladder cancer has a better detection rate than conventional histological examination...
  6. ncbi request reprint Utility of a multiprobe fluorescence in situ hybridization assay in the detection of superficial urothelial bladder cancer
    Mercedes Marín-Aguilera
    Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Cancer Genet Cytogenet 173:131-5. 2007
    ....
  7. ncbi request reprint Clinical utility of fluorescent in situ hybridization for the surveillance of bladder cancer patients treated with bacillus Calmette-Guérin therapy
    Lourdes Mengual
    Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Universitat de Barcelona, Spain
    Eur Urol 52:752-9. 2007
    ..To evaluate the use of a multiprobe fluorescent in situ hybridization (FISH) assay for determining the response of patients with high-risk superficial bladder tumour (HRSBT) to bacillus Calmette-Guérin (BCG) therapy...
  8. doi request reprint Molecular lymph node staging in bladder urothelial carcinoma: impact on survival
    Mercedes Marín-Aguilera
    Laboratory of Urology, Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Barcelona, Spain
    Eur Urol 54:1363-72. 2008
    ..Routine histologic analysis of lymph nodes (LN) for detecting disseminated bladder urothelial carcinoma (BUC) lacks sensitivity...
  9. doi request reprint Utility of urothelial mRNA markers in blood for staging and monitoring bladder cancer
    Mercedes Marín-Aguilera
    Laboratory and Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Urology 79:240.e9-15. 2012
    ..To test the efficiency of 6 mRNA bladder markers in staging urothelial cell carcinoma (UCC) and monitoring UCC dissemination from blood samples...
  10. doi request reprint Using microRNA profiling in urine samples to develop a non-invasive test for bladder cancer
    Lourdes Mengual
    Laboratory and Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Spain
    Int J Cancer 133:2631-41. 2013
    ..Although the data needs to be externally validated, miRNA analysis in urine appears to be a valuable tool for the non-invasive assessment of UCC...
  11. doi request reprint DNA microarray expression profiling of bladder cancer allows identification of noninvasive diagnostic markers
    Lourdes Mengual
    Laboratory of Urology, Urology Department, Hospital Clinic, Barcelona, Spain
    J Urol 182:741-8. 2009
    ..We analyzed bladder cancer gene expression profiles to determine the relevant differentially expressed genes and whether this differential expression is maintained in urine samples...
  12. ncbi request reprint Prognostic value of microRNA expression pattern in upper tract urothelial carcinoma
    Laura Izquierdo
    Department and Laboratory of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    BJU Int 113:813-21. 2014
    ..To examine the microRNA (miRNA) expression pattern in tumour samples from patients with progressing and non-progressing upper tract urothelial carcinoma (UTUC) in order to identify putative miRNAs that may be used as prognostic markers...
  13. pmc Multiplex preamplification of specific cDNA targets prior to gene expression analysis by TaqMan Arrays
    Lourdes Mengual
    Lab and Dept of Urology, Institut Clínic de Nefrologia i Urologia ICNU, Hospital Clinic de Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Villarroel, 170, 08036 Barcelona, Spain
    BMC Res Notes 1:21. 2008
    ....
  14. ncbi request reprint Epithelial-to-mesenchymal transition mediates docetaxel resistance and high risk of relapse in prostate cancer
    Mercedes Marín-Aguilera
    Authors Affiliations Laboratory of Translational Oncology and Medical Oncology Department Bioinformatics Platform Department, Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas CIBEREHD, Hospital Clínic Institut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS Laboratory and Department of Urology, Hospital Clinic, Barcelona Department of Pathology, Hospital Clinic, Universitat de Barcelona Althia Tumor Bank, Hospital Clínic IDIBAPS Biobank, Barcelona Medical Oncology Department, Hospital Germans Trias i Pujol, Catalan Institute of Oncology, Badalona and Medical Oncology Department, Hospital Parc Tauli, Sabadell, Spain
    Mol Cancer Ther 13:1270-84. 2014
    ..This study identifies genes potentially related to chemotherapy resistance and supports evidence of the EMT role in docetaxel resistance and adverse clinical behavior in early prostate cancer...
  15. ncbi request reprint [Non-invasive diagnosis bladder cancer: new molecular markers and future perspectives]
    Mireia Musquera
    Hospital Clinico, Universidad de Barcelona, Barcelona, Espana
    Arch Esp Urol 66:487-94. 2013
    ..In this article we try to perform a review of those markers for bladder cancer already marketed and under development, as well as future diagnostic perspectives. ..
  16. doi request reprint Molecular characterization of upper urinary tract tumours
    Laura Izquierdo
    Department of Urology, Hospital Clinic, Barcelona, Spain
    BJU Int 106:868-72. 2010
    ....
  17. ncbi request reprint Real-time PCR PCA3 assay is a useful test measured in urine to improve prostate cancer detection
    Laura Foj
    Department of Biochemistry and Molecular Genetics CDB, Hospital Clinic, IDIBAPS, Barcelona, Catalonia, Spain
    Clin Chim Acta 435:53-8. 2014
    ..The usefulness of PCA3 in the management of early prostate cancer (PCa) is on debate. The aim of this study was to evaluate PCA3 in the detection of PCa and its relationship with tumor aggressiveness...
  18. ncbi request reprint Utility of fluorescence in situ hybridization as a non-invasive technique in the diagnosis of upper urinary tract urothelial carcinoma
    Mercedes Marín-Aguilera
    Department of Urology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain
    Eur Urol 51:409-15; discussion 415. 2007
    ..To assess the clinical utility of a fluorescence in situ hybridization (FISH) assay as a non-invasive method for diagnosing and monitoring urothelial carcinoma (UC) in the upper urinary tract (UUT)...