Jose Martinez-Orgado

Summary

Country: Spain

Publications

  1. ncbi request reprint Neuroprotective effect of L-arginine in a newborn rat model of acute severe asphyxia
    J Martínez-Orgado
    Area de Neonatología, Fundacion Hospital Alcorcon, Madrid, Spain
    Biol Neonate 88:291-8. 2005
  2. ncbi request reprint [The cannabinoid system and its importance in the perinatal period]
    J A Martínez Orgado
    Area de Pediatría y Neonatología, Fundacion Hospital Alcorcon, Madrid, Espana
    An Pediatr (Barc) 63:433-40. 2005
  3. ncbi request reprint The seek of neuroprotection: introducing cannabinoids
    Jose Martinez-Orgado
    Area de Pediatría y Neonatología, Fundación Hospital Alcorcón Budapest, 1 28922 Alcorcón Madrid, Spain
    Recent Pat CNS Drug Discov 2:131-9. 2007
  4. ncbi request reprint Characterization of the neuroprotective effect of the cannabinoid agonist WIN-55212 in an in vitro model of hypoxic-ischemic brain damage in newborn rats
    David Fernández-López
    Departamento de Farmacologia, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Pediatr Res 60:169-73. 2006
  5. ncbi request reprint Neuroprotection by the cannabinoid agonist WIN-55212 in an in vivo newborn rat model of acute severe asphyxia
    Jose Martinez-Orgado
    Area de Pediatría y Neonatología, Fundacion Hospital Alcorcon, Avda Budapest 1, 28990 Alcorcón, Madrid, Spain
    Brain Res Mol Brain Res 114:132-9. 2003
  6. ncbi request reprint Administration of N(omega)-L-arginine methyl ester (L-NAME) impairs endothelium-dependent relaxation in gravid but not nongravid rats
    Jose Martinez-Orgado
    Area de Pediatría y Neonatología, Fundacion Hospital Alcorcon, Madrid, Spain
    J Soc Gynecol Investig 10:74-81. 2003
  7. ncbi request reprint Impairment of fetal endothelium-dependent relaxation in a rat model of preeclampsia by chronic nitric oxide synthase inhibition
    Jose Martinez-Orgado
    Area de Pediatría y Neonatología, Fundacion Hospital Alcorcon, Madrid, Spain
    J Soc Gynecol Investig 11:82-8. 2004
  8. doi request reprint Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function
    M R Pazos
    Experimental Unit, Foundation for Biomedical Research, Madrid, Spain
    Neuropharmacology 63:776-83. 2012

Collaborators

  • Julian Romero
  • B Bonet
  • Eva Romero
  • M P Viveros
  • M R Pazos
  • David Fernández-López
  • J A Martínez Orgado
  • M Santos
  • V Cinquina
  • A Gomez
  • R Layunta
  • J Fernandez-Ruiz
  • Pedro Lorenzo
  • Estefanía Núñez
  • Maria Angeles Moro
  • Ignacio Lizasoain
  • D Fernández López
  • J Romero Paredes
  • B Bonet Serra
  • I Lizasoain Hernández

Detail Information

Publications8

  1. ncbi request reprint Neuroprotective effect of L-arginine in a newborn rat model of acute severe asphyxia
    J Martínez-Orgado
    Area de Neonatología, Fundacion Hospital Alcorcon, Madrid, Spain
    Biol Neonate 88:291-8. 2005
    ..05). We conclude that L-Arg administration after acute severe asphyxia in newborn rats is neuroprotective, reducing early and delayed neuronal loss...
  2. ncbi request reprint [The cannabinoid system and its importance in the perinatal period]
    J A Martínez Orgado
    Area de Pediatría y Neonatología, Fundacion Hospital Alcorcon, Madrid, Espana
    An Pediatr (Barc) 63:433-40. 2005
    ....
  3. ncbi request reprint The seek of neuroprotection: introducing cannabinoids
    Jose Martinez-Orgado
    Area de Pediatría y Neonatología, Fundación Hospital Alcorcón Budapest, 1 28922 Alcorcón Madrid, Spain
    Recent Pat CNS Drug Discov 2:131-9. 2007
    ..Patents related to cannabinoid receptors are also discussed...
  4. ncbi request reprint Characterization of the neuroprotective effect of the cannabinoid agonist WIN-55212 in an in vitro model of hypoxic-ischemic brain damage in newborn rats
    David Fernández-López
    Departamento de Farmacologia, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Pediatr Res 60:169-73. 2006
    ....
  5. ncbi request reprint Neuroprotection by the cannabinoid agonist WIN-55212 in an in vivo newborn rat model of acute severe asphyxia
    Jose Martinez-Orgado
    Area de Pediatría y Neonatología, Fundacion Hospital Alcorcon, Avda Budapest 1, 28990 Alcorcón, Madrid, Spain
    Brain Res Mol Brain Res 114:132-9. 2003
    ..This effect is achieved through two parallel CB1-dependent and -independent mechanisms...
  6. ncbi request reprint Administration of N(omega)-L-arginine methyl ester (L-NAME) impairs endothelium-dependent relaxation in gravid but not nongravid rats
    Jose Martinez-Orgado
    Area de Pediatría y Neonatología, Fundacion Hospital Alcorcon, Madrid, Spain
    J Soc Gynecol Investig 10:74-81. 2003
    ....
  7. ncbi request reprint Impairment of fetal endothelium-dependent relaxation in a rat model of preeclampsia by chronic nitric oxide synthase inhibition
    Jose Martinez-Orgado
    Area de Pediatría y Neonatología, Fundacion Hospital Alcorcon, Madrid, Spain
    J Soc Gynecol Investig 11:82-8. 2004
    ..We studied fetal endothelial function in a model of preeclampsia induced by Nomega-nitro-l-arginine methylester (L-NAME) administration in pregnant rats...
  8. doi request reprint Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function
    M R Pazos
    Experimental Unit, Foundation for Biomedical Research, Madrid, Spain
    Neuropharmacology 63:776-83. 2012
    ..These effects of CBD were not associated with any side effects. These results emphasize the interest in CBD as a neuroprotective agent for neonatal HI...