Manuel Martinez Selles


Country: Spain


  1. Martinez Selles M, Martinez E, Cortés M, Prieto R, Gallego L, Fernandez Aviles F. Determinants of long-term survival in patients hospitalized for heart failure. J Cardiovasc Med (Hagerstown). 2010;11:164-9 pubmed publisher
    ..The prognosis of patients hospitalized with heart failure is highly variable. A simple risk score, based on six variables readily obtainable on admission can effectively stratify patients according to their predicted mortality. ..
  2. Vicent L, Martínez Sellés H, Ariza Solé A, Lucia A, Emanuele E, Bayes Genis A, et al. A panel of multibiomarkers of inflammation, fibrosis, and catabolism is normal in healthy centenarians but has high values in young patients with myocardial infarction. Maturitas. 2018;116:54-58 pubmed publisher
    ..Disease-free centenarians had significantly lower levels of inflammation, fibrosis, and catabolism biomarkers than young patients with myocardial infarction. Advanced aging per se is not invariably associated with these biomarkers. ..
  3. Pérez Castellanos A, Martinez Selles M, Uribarri A, Devesa Cordero C, Sánchez Salado J, Ariza Solé A, et al. Development and External Validation of an Early Prognostic Model for Survivors of Out-of-hospital Cardiac Arrest. Rev Esp Cardiol (Engl Ed). 2018;: pubmed publisher
    ..82 (95%CI, 0.73-0.91). A predictive model that includes 5 clinical and easily accessible variables at admission can help to predict the probability of survival without major neurological damage following out-of-hospital cardiac arrest. ..
  4. González Saldívar H, Vicent Alaminos L, Rodriguez Pascual C, de la Morena G, Fernandez Golfin C, Amorós C, et al. Prognosis of Patients With Severe Aortic Stenosis After the Decision to Perform an Intervention. Rev Esp Cardiol (Engl Ed). 2019;72:392-397 pubmed publisher
    ..3; 95%CI, 1.02-5.03). Patients with severe aortic stenosis awaiting therapeutic procedures have a high mortality risk. Some clinical indicators predict a worse prognosis and suggest the need for early intervention. ..
  5. Vicent L, Saldivar H, Bouza E, Munoz P, Cuerpo G, de Alarcon A, et al. Prognostic implications of a negative echocardiography in patients with infective endocarditis. Eur J Intern Med. 2018;52:40-48 pubmed publisher
    ..02-1.76, p = 0.036), possible IE (OR 1.59, 95% CI 1.02-2.45, p = 0.036). A positive echocardiography in patients with IE is associated with increased inhospital mortality, in addition to other clinical factors and comorbidities. ..
  6. Datino T, Rexach L, Vidán M, Alonso A, Gándara Ã, Ruiz García J, et al. Guidelines on the management of implantable cardioverter defibrillators at the end of life. Rev Clin Esp (Barc). 2014;214:31-7 pubmed publisher
  7. Martínez Sellés M, Díez Villanueva P, Sánchez Sendin D, Carro Hevia A, Gómez Doblas J, García de la Villa B, et al. Comorbidity and intervention in octogenarians with severe symptomatic aortic stenosis. Int J Cardiol. 2015;189:61-6 pubmed publisher
    ..5%, p = 0.008). One sixth of octogenarians with symptomatic severe AS have very high comorbidity (Charlson index ≥ 5). These patients have a poor prognosis in the short term and do not seem to benefit from interventional treatment. ..
  8. Martínez Sellés M, García de la Villa B, Cruz Jentoft A, Vidán M, Gil P, Cornide L, et al. Centenarians and their hearts: A prospective registry with comprehensive geriatric assessment, electrocardiogram, echocardiography, and follow-up. Am Heart J. 2015;169:798-805.e2 pubmed publisher
    ..More than one fifth has atrial fibrillation, and most have diastolic dysfunction. Left ventricular dilation was associated with the ability to walk 6 m. Significant abnormalities in echocardiography were associated with mortality. ..
  9. Martínez Sellés M, Pérez David E, Yotti R, Jiménez Borreguero J, Loughlin G, Gallego L, et al. Gender differences in right ventricular function in patients with non-ischaemic cardiomyopathy. Neth Heart J. 2015;23:578-84 pubmed publisher
    ..08. In patients with dilated cardiomyopathy, RV systolic dysfunction is found mainly in male patients with severe LV systolic dysfunction. ..

More Information


  1. Martínez Sellés M, Massó van Roessel A, Álvarez García J, García de la Villa B, Cruz Jentoft A, Vidán M, et al. Interatrial block and atrial arrhythmias in centenarians: Prevalence, associations, and clinical implications. Heart Rhythm. 2016;13:645-51 pubmed publisher
    ..Our data suggested that IAB, particularly advanced IAB, is a pre-atrial fibrillation condition associated with premature atrial beats. Atrial arrhythmias and IAB occurred more frequently in centenarians than in septuagenarians. ..
  2. Martínez Sellés M, Gómez Huelgas R, Abu Assi E, Calderón A, Vidán M. [Chronic ischaemic heart disease in the elderly]. Med Clin (Barc). 2016;146:372.e1-372.e10 pubmed publisher
    ..We conclude that in most patients medical treatment is the best option and that this treatment must take into account the above factors and the biological changes associated with aging. ..
  3. Martinez Selles M, Gomez Huelgas R, Abu Assi E, Calderon A, Vidan M. [Chronic ischaemic heart disease in the elderly]. Semergen. 2017;43:109-122 pubmed publisher
    ..We conclude that in most patients medical treatment is the best option and that this treatment must take into account the above factors and the biological changes associated with aging. ..
  4. Martinez Selles M, Gómez Huelgas R, Abu Assi E, Calderon A, Vidán M. [Chronic ischaemic heart disease in the elderly]. Rev Esp Geriatr Gerontol. 2016;51:170-9 pubmed publisher
    ..We conclude that in most patients medical treatment is the best option and that this treatment must take into account the above factors and the biological changes associated with aging. ..
  5. Hugo G, Figueiras Graillet L, Anguita M, Marin F, Bertomeu V, Roldan I, et al. Oral anticoagulation in octogenarians with atrial fibrillation. Int J Cardiol. 2016;223:87-90 pubmed publisher
    ..In this large registry octogenarians with nonvalvular AF had high risk of stroke and bleeding and frequent renal disease. VKAs anticoagulation quality was similar in octogenarians and in younger patients. ..
  6. Li X, Sousa Casasnovas I, Devesa C, Juarez M, Fernandez Aviles F, Martinez Selles M. Predictors of in-hospital mortality among cardiogenic shock patients. Prognostic and therapeutic implications. Int J Cardiol. 2016;224:114-118 pubmed publisher
    ..This and other prognostic variables (age, blood glucose, and heart rate) may be useful for risk stratification and to select appropriate medical or invasive interventions. ..
  7. Diez Delhoyo F, Valero Masa M, Velásquez Rodríguez J, Devesa Cordero C, Sousa Casasnovas I, Juarez M, et al. Very low risk ST-segment elevation myocardial infarction? It exists and may be easily identified. Int J Cardiol. 2017;228:615-620 pubmed publisher
    ..About a fifth of STEMI patients have VLR and can be easily identified. They have an excellent prognosis suggesting that 24-48h in-hospital stay could be a feasible alternative in these patients. ..
  8. Vicent L, Ayesta A, Vidán M, Miguel Yanes J, Garcia J, Tamargo M, et al. [Profile of heart failure according to the department of admission. Implications for multidisciplinary management]. Rev Esp Geriatr Gerontol. 2017;52:182-187 pubmed publisher
    ..1 - 8.6], p=.03), with no other significant comparisons. Patients admitted due to decompensated heart failure are elderly and often have comorbidities. There are major differences between departments as regards age and clinical profile. ..
  9. Martinez Selles M, Munoz P, Estevez A, del Castillo R, Garcia Fernandez M, Rodriguez Creixems M, et al. Long-term outcome of infective endocarditis in non-intravenous drug users. Mayo Clin Proc. 2008;83:1213-7 pubmed publisher
    ..Survival was similar for patients with native-valve IE and those with prosthetic-valve IE. Survival was also similar for patients who underwent surgery during hospitalization and those who did not. ..
  10. González Saldívar H, Rodriguez Pascual C, de la Morena G, Fernandez Golfin C, Amorós C, Alonso M, et al. Comparison of 1-Year Outcome in Patients With Severe Aorta Stenosis Treated Conservatively or by Aortic Valve Replacement or by Percutaneous Transcatheter Aortic Valve Implantation (Data from a Multicenter Spanish Registry). Am J Cardiol. 2016;118:244-50 pubmed publisher
    ..The outcome in asymptomatic patients managed conservatively was acceptable. Management in tertiary hospitals is associated with valve intervention. One-year survival was similar with both interventional strategies. ..
  11. Martinez Selles M, Fernandez Lozano I, Baranchuk A, Bayes Genis A, Bayes de Luna A. Should We Anticoagulate Patients at High Risk of Atrial Fibrillation?. Rev Esp Cardiol (Engl Ed). 2016;69:374-6 pubmed publisher
  12. Velásquez Rodríguez J, Diez Delhoyo F, Valero Masa M, Vicent L, Devesa C, Sousa Casasnovas I, et al. Prognostic Impact of Age and Hemoglobin in Acute ST-Segment Elevation Myocardial Infarction Treated With Reperfusion Therapy. Am J Cardiol. 2017;119:1909-1916 pubmed publisher
    ..This association is also present in men ≥65 years with normal hemoglobin levels. ..
  13. Vicent L, Nunez Olarte J, Puente Maestu L, Oliva A, Lopez J, Postigo A, et al. Degree of dyspnoea at admission and discharge in patients with heart failure and respiratory diseases. BMC Palliat Care. 2017;16:35 pubmed publisher
    ..65.6±1.0, p=0.006). About a quarter of patients admitted with HF or RD persist with severe dyspnoea at discharge. Opioids are probably underused. HF patients have less dyspnoea than patients with RD but present worse quality of life. ..
  14. Vicent L, Martinez Selles M. Electrocardiogeriatrics: ECG in advanced age. J Electrocardiol. 2017;50:698-700 pubmed publisher
    ..Interatrial block (IAB) is frequently present, mainly partial IAB. Atrial fibrillation prevalence raises from 6-7% in those aged 65-74years to 13-17% in those >75years. ..
  15. Bayés de Luna A, Martínez Sellés M, Bayés Genís A, Elosua R, Baranchuk A. Surface ECG interatrial block-guided treatment for stroke prevention: rationale for an attractive hypothesis. BMC Cardiovasc Disord. 2017;17:211 pubmed publisher
    ..In this debate, we discuss the association of surface ECG IAB, a marker of atrial fibrosis, with AF and stroke. We also present the rationale that justifies further studies regarding anticoagulation in some of these patients. ..
  16. Valero Masa M, Velásquez Rodríguez J, Diez Delhoyo F, Devesa C, Juarez M, Sousa Casasnovas I, et al. Sex differences in acute myocardial infarction: Is it only the age?. Int J Cardiol. 2017;231:36-41 pubmed publisher
    ..71, 95% CI 0.97-2.99) or long-term mortality (HR 1.0, 95% CI 0.7-1.5). In patients with acute STEMI, the association of female sex with poor prognosis is mainly explained by age. Sex does not seem to be an independent prognostic factor. ..
  17. Ayesta A, Sousa Casasnovas I, Gómez E, Martinez Selles M, Fernandez Aviles F. Outpatient follow-up during the first year after heart transplantation, is it feasible?. Int J Cardiol. 2017;228:1-3 pubmed publisher
    ..No difference was found in 1-year mortality (IF 2.3% vs. 1.0%, p=0.60). First year post-cardiac transplantation outpatient follow-up seems to be feasible and safe in terms of infection, rejection, vascular complications and mortality. ..
  18. Vicent L, Velásquez Rodríguez J, Valero Masa M, Diez Delhoyo F, González Saldívar H, Bruña V, et al. Predictors of high Killip class after ST segment elevation myocardial infarction in the era of primary reperfusion. Int J Cardiol. 2017;248:46-50 pubmed publisher
    ..5%, II 3.7%, III 16.7%, IV 36.7%). In patients with STEMI Killip class can be predicted with variables available when primary percutaneous coronary intervention is performed and is strongly associated with in-hospital prognosis. ..