- Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancementShira Knafo
Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas CSIC Universidad Autónoma de Madrid, Madrid, Spain
PLoS Biol 10:e1001262. 2012..These results provide a mechanistic link between facilitation of AMPA receptor synaptic delivery and improved hippocampal-dependent learning, induced by a pharmacological cognitive enhancer...
- Common pathways for growth and for plasticityShira Knafo
Centro de Biologia Molecular Severo Ochoa CSIC UAM, Nicolas Cabrera 1, Madrid 28049, Spain
Curr Opin Neurobiol 22:405-11. 2012..Here we review the latest findings on two prototypical examples of these shared mechanisms: the Ras-PI3K pathway and the intracellular signaling elicited by neural cell adhesion molecules interacting with growth factor receptors...
- DREAM controls the on/off switch of specific activity-dependent transcription pathwaysBritt Mellstrom
National Center of Biotechnology, CSIC and CIBERNED, Madrid, Spain
Mol Cell Biol 34:877-87. 2014..Our results indicate that DREAM is a major master switch transcription factor that regulates the on/off status of specific activity-dependent gene expression programs that control synaptic plasticity, learning, and memory. ..
- Morphological alterations to neurons of the amygdala and impaired fear conditioning in a transgenic mouse model of Alzheimer's diseaseShira Knafo
Instituto Cajal CSIC, Madrid, Spain
J Pathol 219:41-51. 2009..We suggest that these morphological changes in the neurons of the LA may contribute to the impaired auditory fear conditioning seen in this AD model...