W Jimenez

Summary

Country: Spain

Publications

  1. ncbi request reprint Long-term aquaretic efficacy of a selective nonpeptide V(2)-vasopressin receptor antagonist, SR121463, in cirrhotic rats
    W Jimenez
    Hormonal Laboratory, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic Universitari, University of Barcelona and Instituto Reina Sofia de Investigaciones Nefrológicas, Barcelona, Spain
    J Pharmacol Exp Ther 295:83-90. 2000
  2. ncbi request reprint Nitric oxide production and inducible nitric oxide synthase expression in peritoneal macrophages of cirrhotic patients
    W Jimenez
    Hormonal Laboratory, Hospital Clínic Universitari and Institut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Hepatology 30:670-6. 1999
  3. doi request reprint Adenoviral dominant-negative soluble PDGFRβ improves hepatic collagen, systemic hemodynamics, and portal pressure in fibrotic rats
    V Reichenbach
    Biochemistry and Molecular Genetics Service, Hospital Clínic Provincial de Barcelona, IDIBAPS, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Barcelona, Spain
    J Hepatol 57:967-73. 2012
  4. ncbi request reprint Renal and neurohormonal changes following simultaneous administration of systemic vasoconstrictors and dopamine or prostacyclin in cirrhotic patients with hepatorenal syndrome
    J Salo
    Department of Medicine, Hospital Clinic i Provincial, Barcelona, Spain
    J Hepatol 25:916-23. 1996
  5. doi request reprint Vascular endothelial growth factor and angiopoietin-2 play a major role in the pathogenesis of vascular leakage in cirrhotic rats
    P Melgar-Lesmes
    Biochemistry and Molecular Genetics Service, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Gut 58:285-92. 2009
  6. doi request reprint Inactivation of extrahepatic vascular Akt improves systemic hemodynamics and sodium excretion in cirrhotic rats
    G Fernandez-Varo
    Biochemistry and Molecular Genetics Service, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, University of Barcelona, Barcelona, Spain
    J Hepatol 53:1041-8. 2010
  7. ncbi request reprint Randomized trial comparing albumin, dextran 70, and polygeline in cirrhotic patients with ascites treated by paracentesis
    A Gines
    Liver Unit, Hospital Clinic i Provincial, Barcelona, Spain
    Gastroenterology 111:1002-10. 1996
  8. ncbi request reprint Complications of cirrhosis. II. Renal and circulatory dysfunction. Lights and shadows in an important clinical problem
    V Arroyo
    Institute of Digestive Diseases and Hormonal Laboratory, Hospital Clinic Universitari, University of Barcelona, Spain
    J Hepatol 32:157-70. 2000
  9. pmc Increased anandamide induced relaxation in mesenteric arteries of cirrhotic rats: role of cannabinoid and vanilloid receptors
    M Domenicali
    Laboratorio Hormonal, Hospital Clinic Universitari, Villarroel 170, Barcelona 08036, Spain
    Gut 54:522-7. 2005
  10. ncbi request reprint [Ascites and vascular dysfunction in human liver cirrhosis: new pathophysiologic concepts for a severe complication]
    M Morales-Ruiz
    Laboratorio de Hormonas, Hospital Clinic Universitari, Institut d Investigacions Biomèdiques August Pi i Sunyer e Instituto Reina Sofía de Investigaciones Nefrológicas, Universidad de Barcelona, Barcelona
    Nefrologia 23:58-61. 2003

Collaborators

  • V Arroyo
  • P Gines
  • J M Campistol
  • R Abecasis
  • J M Sanchez-Tapias
  • P Angeli
  • X Forns
  • R Sola
  • A Cardenas
  • F Salerno
  • G Fernandez-Varo
  • M Morales-Ruiz
  • J Ros
  • P Melgar-Lesmes
  • J Rodes
  • P Cejudo-Martin
  • V Reichenbach
  • S M Martinez
  • G Casals
  • G Fernandez-Esparrach
  • M Navasa
  • M Domenicali
  • D Oro
  • R Weiskirchen
  • P Gonzalez
  • M Bruguera
  • E Sampson
  • M Pauta
  • S Tugues
  • A Gines
  • M Guevara
  • R Bataller
  • L Ruiz-del-Arbol
  • A M Briones
  • E Vila
  • M Crespo
  • R Planas
  • J Salo
  • J C Quer
  • L Quinto
  • F Rivera
  • P J Ventura
  • J Fernandez
  • J Uriz
  • P Sort
  • A Sanchez-Fueyo
  • R Terg
  • P Vaque
  • C Vila
  • G Clemente
  • L Inglada
  • A Monescillo
  • V Vargas
  • E Domenech

Detail Information

Publications14

  1. ncbi request reprint Long-term aquaretic efficacy of a selective nonpeptide V(2)-vasopressin receptor antagonist, SR121463, in cirrhotic rats
    W Jimenez
    Hormonal Laboratory, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic Universitari, University of Barcelona and Instituto Reina Sofia de Investigaciones Nefrológicas, Barcelona, Spain
    J Pharmacol Exp Ther 295:83-90. 2000
    ..During the first 6 days of treatment, SR121463 also increased U(Na)V without affecting mean arterial pressure. These data suggest that SR121463 could be of therapeutical value for chronic management of human cirrhosis...
  2. ncbi request reprint Nitric oxide production and inducible nitric oxide synthase expression in peritoneal macrophages of cirrhotic patients
    W Jimenez
    Hormonal Laboratory, Hospital Clínic Universitari and Institut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Hepatology 30:670-6. 1999
    ....
  3. doi request reprint Adenoviral dominant-negative soluble PDGFRβ improves hepatic collagen, systemic hemodynamics, and portal pressure in fibrotic rats
    V Reichenbach
    Biochemistry and Molecular Genetics Service, Hospital Clínic Provincial de Barcelona, IDIBAPS, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Barcelona, Spain
    J Hepatol 57:967-73. 2012
    ..Thereafter, we investigated the effects produced by an adenovirus encoding a dominant-negative soluble PDGFRβ (sPDGFRβ) on hemodynamic parameters, PDGFRβ signaling pathway, and fibrosis...
  4. ncbi request reprint Renal and neurohormonal changes following simultaneous administration of systemic vasoconstrictors and dopamine or prostacyclin in cirrhotic patients with hepatorenal syndrome
    J Salo
    Department of Medicine, Hospital Clinic i Provincial, Barcelona, Spain
    J Hepatol 25:916-23. 1996
    ..The renal effects of the i.v. infusion of norepinephrine plus prostacyclin in patients with hepatorenal syndrome were also assessed...
  5. doi request reprint Vascular endothelial growth factor and angiopoietin-2 play a major role in the pathogenesis of vascular leakage in cirrhotic rats
    P Melgar-Lesmes
    Biochemistry and Molecular Genetics Service, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Gut 58:285-92. 2009
    ....
  6. doi request reprint Inactivation of extrahepatic vascular Akt improves systemic hemodynamics and sodium excretion in cirrhotic rats
    G Fernandez-Varo
    Biochemistry and Molecular Genetics Service, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, University of Barcelona, Barcelona, Spain
    J Hepatol 53:1041-8. 2010
    ..Ultimately, we sought to determine whether endothelial transduction of a constitutively inactive mutant of Akt (AA-Akt) improves circulatory function and sodium excretion in cirrhotic rats with ascites...
  7. ncbi request reprint Randomized trial comparing albumin, dextran 70, and polygeline in cirrhotic patients with ascites treated by paracentesis
    A Gines
    Liver Unit, Hospital Clinic i Provincial, Barcelona, Spain
    Gastroenterology 111:1002-10. 1996
    ..This study investigated the clinical importance of paracentesis-induced-circulatory dysfunction and compared the efficacy of albumin, dextran 70, and polygeline in preventing this complication...
  8. ncbi request reprint Complications of cirrhosis. II. Renal and circulatory dysfunction. Lights and shadows in an important clinical problem
    V Arroyo
    Institute of Digestive Diseases and Hormonal Laboratory, Hospital Clinic Universitari, University of Barcelona, Spain
    J Hepatol 32:157-70. 2000
    ..The mechanism of bacterial translocation and of the colonization of bacteria in the ascitic fluid are particularly important to design adequate measures for primary prophylaxis of this severe bacterial infection...
  9. pmc Increased anandamide induced relaxation in mesenteric arteries of cirrhotic rats: role of cannabinoid and vanilloid receptors
    M Domenicali
    Laboratorio Hormonal, Hospital Clinic Universitari, Villarroel 170, Barcelona 08036, Spain
    Gut 54:522-7. 2005
    ..As anandamide has been implicated in the vasodilated state in advanced cirrhosis, the study investigated whether the mesenteric bed from cirrhotic rats has an altered and selective vasodilator response to anandamide...
  10. ncbi request reprint [Ascites and vascular dysfunction in human liver cirrhosis: new pathophysiologic concepts for a severe complication]
    M Morales-Ruiz
    Laboratorio de Hormonas, Hospital Clinic Universitari, Institut d Investigacions Biomèdiques August Pi i Sunyer e Instituto Reina Sofía de Investigaciones Nefrológicas, Universidad de Barcelona, Barcelona
    Nefrologia 23:58-61. 2003
  11. pmc Origins of cardiac dysfunction in cirrhosis
    W Jimenez
    Hormonal Laboratory, Hospital Clinic, University of Barcelona, Spain
    Gut 52:1392-4. 2003
  12. doi request reprint Assessment of liver fibrosis before and after antiviral therapy by different serum marker panels in patients with chronic hepatitis C
    S M Martinez
    Hospital Clinic, IDIBAPS and Ciberehd, Barcelona, Spain
    Aliment Pharmacol Ther 33:138-48. 2011
    ..Liver biopsy is the reference standard to assess liver fibrosis in chronic hepatitis C...
  13. ncbi request reprint Increased production of vascular endothelial growth factor in peritoneal macrophages of cirrhotic patients with spontaneous bacterial peritonitis
    P Cejudo-Martin
    Hormonal Laboratory, Hospital Clínic Universitari and Institut d Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Hepatology 34:487-93. 2001
    ..These results, therefore, are consistent with the concept that locally released macrophage-derived VEGF may result in increased vascular permeability and plasma leakage in the peritoneal vessels of cirrhotic patients with SBP...
  14. ncbi request reprint A prognostic model for predicting survival in cirrhosis with ascites
    G Fernandez-Esparrach
    Liver Unit, Institut de Malalties Digestives, Hospital Clinic, IDIBAPS, Barcelona, Spain
    J Hepatol 34:46-52. 2001
    ..The aim of the current study was to develop a prognostic model to estimate survival of patients with cirrhosis and ascites...