Research Topics
| E F EspejoSummaryAffiliation: Instituto de la Grasa Country: Spain Publications
| Collaborators
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Detail Information
Publications
Structure of the mouse behaviour on the elevated plus-maze test of anxietyE Fernandez Espejo
Departamento de Fisiologia Medica, Facultad de Medicina, Universidad de Sevilla, Spain
Behav Brain Res 86:105-12. 1997..Results should be taken into account if the effects of drugs or CNS manipulations on Swiss mouse behaviour on the elevated plus-maze are analyzed...
Adrenergic hyperactivity and metanephrine excess in the nucleus accumbens after prefrontocortical dopamine depletionE F Espejo
Departamento de Fisiologia Medica y Biofisica, Facultad de Medicina, Universidad de Sevilla, E 41009 Seville, Spain
J Neurophysiol 85:1270-4. 2001....
[How does the nucleus accumbens function?]E Fernandez-Espejo
Departamento de Fisiologia Medica, Facultad de Medicina, Universidad de Sevilla, Espana
Rev Neurol 30:845-9. 2000..The nucleus accumbens is considered as the neural interface between motivation and action, playing a key role on feeding, sexual, reward, stress-related, drug self-administration behaviors, etc...
Antagonism of peripheral 5-HT4 receptors reduces visceral and cutaneous pain in mice, and induces visceral analgesia after simultaneous inactivation of 5-HT3 receptorsE F Espejo
Departamento de Fisiologia Medica, Universidad de Sevilla, Sevilla, Spain
Brain Res 788:20-4. 1998....
Effects of weekly or daily exposure to the elevated plus-maze in male miceE F Espejo
Departamento de Fisiologia Medica, Universidad de Sevilla, Spain
Behav Brain Res 87:233-8. 1997..In conclusion, the findings of the present study support the hypothesis that anxiety is enhanced after test repetition, and indicate that test-retest profiles are far from stable, except for exploratory locomotor activity...
Selective dopamine depletion within the medial prefrontal cortex induces anxiogenic-like effects in rats placed on the elevated plus mazeE F Espejo
Departamento de Fisiologia Medica y Biofisica, Universidad de Sevilla, Seville, Spain
Brain Res 762:281-4. 1997..The findings confirm that prefrontocortical dopamine activation is necessary for coping with an anxiogenic challenge, allowing the animal to display adaptive exploratory responses in a fear-inducing environment...
Single restraint stress sensitizes acute chewing movements induced by haloperidol, but not if the 5-HT1A agonist 8-OH-DPAT is given prior to stressE Fdez Espejo
Depto de Fisiología Medica y Biofísica, Universidad de Sevilla, Seville, Spain
Brain Res 755:351-5. 1997..25, 0.5 mg/kg i.p.). Interestingly, this behavioral sensitization was prevented by 8-OH-DPAT (0.35 mg/kg s.c.) prior to stress. Finally, haloperidol-induced sedation was not disrupted by either restraint stress or 8-OH-DPAT treatment...
Behavioral expression of opiate withdrawal is altered after prefrontocortical dopamine depletion in rats: monoaminergic correlatesE F Espejo
Departmento de Fisiologia Medica, Facultad de Medicina, Universidad de Sevilla, Sevilla, Spain
Neuropsychopharmacology 25:204-12. 2001....
Functional regeneration in a rat Parkinson's model after intrastriatal grafts of glial cell line-derived neurotrophic factor and transforming growth factor beta1-expressing extra-adrenal chromaffin cells of the Zuckerkandl's organE F Espejo
Departamento de Fisiologia Medica y Biofisica, Universidad de Sevilla, E 41009 Sevilla, Spain
J Neurosci 21:9888-95. 2001..This work should stimulate research on the clinical applicability of transplants of the Zuckerkandl's organ in Parkinson's disease...
[Natural "dopaminotrophic" cell transplant: a new concept in antiparkinsonian therapy]E Fernandez-Espejo
Departamento de Fisiologia Medica y Biofisica, Universidad de Sevilla Sevilla, Espana
Rev Neurol 36:540-4. 2003..CONCLUSION: Our result should stimulate research on the clinical applicability of transplants of the Zuckerkandl s organ in Parkinson s disease..
[Neurobiological basis of drug addiction]E Fernandez-Espejo
Departamento de Fisiologia Medica, Universidad de Sevilla, Facultad de Medicina, Sevilla, Espana
Rev Neurol 34:659-64. 2002..Furthermore, these neural changes appear to subserve the emergence of cravings once the abstinent syndrome has been overcome. Cravings are the main factor leading to relapse, and they are often initiated by exposure to drug related cues...
[The neurobiology of psychostimulant addiction]E Fernandez-Espejo
Departamento de Fisiologia Medica, Universidad de Sevilla Facultad de Medicina, 41009 Sevilla, Spain
Rev Neurol 43:147-54. 2006..CONCLUSION: All together leads to a consolidated addiction, considered as an anomalous learning process, along with a loss of control over drug taking...
