Carmen Cañavate

Summary

Affiliation: Instituto de Salud Carlos III
Country: Spain

Publications

  1. pmc Evaluation of two rK39 dipstick tests, direct agglutination test, and indirect fluorescent antibody test for diagnosis of visceral leishmaniasis in a new epidemic site in highland Ethiopia
    Carmen Cañavate
    World Health Organization Collaborating Center for Leishmaniasis, National Center of Microbiology, Instituto de Salud Carlos III, Madrid, Spain
    Am J Trop Med Hyg 84:102-6. 2011
  2. pmc Sequence analysis of the 3'-untranslated region of HSP70 (type I) genes in the genus Leishmania: its usefulness as a molecular marker for species identification
    Jose M Requena
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, 28049 Madrid, Spain
    Parasit Vectors 5:87. 2012
  3. pmc Fatal congenital Chagas' disease in a non-endemic area: a case report
    Maria Flores-Chavez
    Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra, Pozuelo Majadahonda Km 2, 28220 Majadahonda, Madrid, Spain
    Cases J 1:302. 2008
  4. ncbi request reprint Isolation and characterization of Leishmania infantum cDNA encoding a protein homologous to eukaryotic elongation factor 1 gamma
    Carmen Cañavate
    WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra Majadahonda Pozuelo km 2, 28220 Majadahonda, Madrid, Spain
    Trans R Soc Trop Med Hyg 96:S41-7. 2002
  5. pmc Comparison of new diagnostic tools for management of pediatric Mediterranean visceral leishmaniasis
    Israel Cruz
    WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra Pozuelo Majadahonda Km 2, 28220 Majadahonda, Madrid, Spain
    J Clin Microbiol 44:2343-7. 2006
  6. pmc Factors associated with Leishmania asymptomatic infection: results from a cross-sectional survey in highland northern Ethiopia
    Estefanía Custodio
    Centro Nacional de Medicina Tropical, Instituto de Salud Carlos III, Madrid, Spain
    PLoS Negl Trop Dis 6:e1813. 2012
  7. doi request reprint Transfusional chagas disease: parasitological and serological monitoring of an infected recipient and blood donor
    Maria Flores-Chavez
    Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Madrid, Spain
    Clin Infect Dis 46:e44-7. 2008
  8. doi request reprint Immunogenicity of HSP-70, KMP-11 and PFR-2 leishmanial antigens in the experimental model of canine visceral leishmaniasis
    Eugenia Carrillo
    WHO Collaborating Centre for Leishmaniasis, Centro Nacional de Microbiologia, Inst de Salud Carlos III, Majadahonda, Spain
    Vaccine 26:1902-11. 2008
  9. doi request reprint [Comparison of conventional and non-conventional serological tests for the diagnosis of imported Chagas disease in Spain]
    Maria Flores-Chavez
    Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Madrid, Espana
    Enferm Infecc Microbiol Clin 28:284-93. 2010
  10. pmc Sensitivity and specificity of an operon immunochromatographic test in serum and whole-blood samples for the diagnosis of Trypanosoma cruzi infection in Spain, an area of nonendemicity
    Maria Flores-Chavez
    Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain
    Clin Vaccine Immunol 19:1353-9. 2012

Collaborators

Detail Information

Publications18

  1. pmc Evaluation of two rK39 dipstick tests, direct agglutination test, and indirect fluorescent antibody test for diagnosis of visceral leishmaniasis in a new epidemic site in highland Ethiopia
    Carmen Cañavate
    World Health Organization Collaborating Center for Leishmaniasis, National Center of Microbiology, Instituto de Salud Carlos III, Madrid, Spain
    Am J Trop Med Hyg 84:102-6. 2011
    ..4%). Both rK39 immunochromatographic tests perform as well as DAT, and are suitable for VL diagnosis in first-level health centers in this area of Ethiopia...
  2. pmc Sequence analysis of the 3'-untranslated region of HSP70 (type I) genes in the genus Leishmania: its usefulness as a molecular marker for species identification
    Jose M Requena
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, 28049 Madrid, Spain
    Parasit Vectors 5:87. 2012
    ..Recently, sequencing of the HSP70 coding region has been applied in phylogenetic studies and for identifying of Leishmania species with excellent results...
  3. pmc Fatal congenital Chagas' disease in a non-endemic area: a case report
    Maria Flores-Chavez
    Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra, Pozuelo Majadahonda Km 2, 28220 Majadahonda, Madrid, Spain
    Cases J 1:302. 2008
    ..This paper describes the complications arising in the diagnosis of a newborn with fatal congenital Chagas' disease in Spain, a non-endemic area where visceral leishmaniasis is present...
  4. ncbi request reprint Isolation and characterization of Leishmania infantum cDNA encoding a protein homologous to eukaryotic elongation factor 1 gamma
    Carmen Cañavate
    WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra Majadahonda Pozuelo km 2, 28220 Majadahonda, Madrid, Spain
    Trans R Soc Trop Med Hyg 96:S41-7. 2002
    ..Southern hybridization and pulsed field gel electrophoresis showed that EF-1 gamma genes are highly conserved among members of the Leishmania genus and must be clustered in a single chromosomal locus...
  5. pmc Comparison of new diagnostic tools for management of pediatric Mediterranean visceral leishmaniasis
    Israel Cruz
    WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra Pozuelo Majadahonda Km 2, 28220 Majadahonda, Madrid, Spain
    J Clin Microbiol 44:2343-7. 2006
    ..All of the new noninvasive techniques tested showed high diagnostic sensitivity. However, LnPCR analysis of the bone marrow was the most sensitive; this test was able to detect the persistence of parasites and predict potential relapses...
  6. pmc Factors associated with Leishmania asymptomatic infection: results from a cross-sectional survey in highland northern Ethiopia
    Estefanía Custodio
    Centro Nacional de Medicina Tropical, Instituto de Salud Carlos III, Madrid, Spain
    PLoS Negl Trop Dis 6:e1813. 2012
    ..In order to develop effective control strategies on the transmission of the disease it is important to generate knowledge on the epidemiological determinants of the infection...
  7. doi request reprint Transfusional chagas disease: parasitological and serological monitoring of an infected recipient and blood donor
    Maria Flores-Chavez
    Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Madrid, Spain
    Clin Infect Dis 46:e44-7. 2008
    ..Before undergoing immunosuppression, multitransfused patients should be screened for anti-Trypanosoma cruzi antibodies...
  8. doi request reprint Immunogenicity of HSP-70, KMP-11 and PFR-2 leishmanial antigens in the experimental model of canine visceral leishmaniasis
    Eugenia Carrillo
    WHO Collaborating Centre for Leishmaniasis, Centro Nacional de Microbiologia, Inst de Salud Carlos III, Majadahonda, Spain
    Vaccine 26:1902-11. 2008
    ..The identification as vaccine candidates of Leishmania antigens that elicit appropriate immune responses in the canine model is a key step in the rational approach to generate a vaccine for canine visceral leishmaniasis...
  9. doi request reprint [Comparison of conventional and non-conventional serological tests for the diagnosis of imported Chagas disease in Spain]
    Maria Flores-Chavez
    Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Madrid, Espana
    Enferm Infecc Microbiol Clin 28:284-93. 2010
    ..cruzi antibodies, to assess their cross-reactivity with related diseases, and to evaluate the rk39-ELISA and IFAT-Leishmania tests as tools for the differential diagnosis of leishmaniasis due to Leishmania infantum...
  10. pmc Sensitivity and specificity of an operon immunochromatographic test in serum and whole-blood samples for the diagnosis of Trypanosoma cruzi infection in Spain, an area of nonendemicity
    Maria Flores-Chavez
    Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain
    Clin Vaccine Immunol 19:1353-9. 2012
    ..ICT-Operon showed variable sensitivity, depending on the kind of sample, performing better when serum or plasma samples were used. It could therefore be used for serological screening combined with any other conventional test...
  11. doi request reprint An approach for interlaboratory comparison of conventional and real-time PCR assays for diagnosis of human leishmaniasis
    Israel Cruz
    WHO Collaborating Center for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra Majadahonda Pozuelo, Km2, 28220 Madrid, Spain
    Exp Parasitol 134:281-9. 2013
    ....
  12. pmc A canine leishmaniasis pilot survey in an emerging focus of visceral leishmaniasis: Posadas (Misiones, Argentina)
    Israel Cruz
    WHO Collaborating Centre for Leishmaniasis, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Madrid, Spain
    BMC Infect Dis 10:342. 2010
    ..This event encouraged us to conduct a clinical and parasitological pilot survey on domestic dogs from Posadas to identify their potential role as reservoirs for the disease...
  13. ncbi request reprint Canine leishmaniasis
    Jorge Alvar
    WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain
    Adv Parasitol 57:1-88. 2004
    ....
  14. pmc Ddi1-like protein from Leishmania major is an active aspartyl proteinase
    María J Perteguer
    Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, 28220 Madrid, Spain
    Cell Stress Chaperones 18:171-81. 2013
    ..Our results indicate that the isolated Ddi1-like protein is a functional aspartyl proteinase in L. major, opening possibility to be considered as a potential target for novel antiparasitic drugs...
  15. pmc Low prevalence of Leishmania infection in post-epidemic areas of Libo Kemkem, Ethiopia
    Luis Sordo
    Centro Nacional de Epidemiologia, Instituto de Salud Carlos III, CIBER en Epidemiología y Salud Pública CIBERESP, Madrid, Spain
    Am J Trop Med Hyg 86:955-8. 2012
    ..Only one case of active disease was encountered. The results suggest that the conditions responsible for the outbreak no longer reign. However, active surveillance remains necessary...
  16. doi request reprint Multicentric, controlled clinical study to evaluate effectiveness and safety of miltefosine and allopurinol for canine leishmaniosis
    Guadalupe Miró
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense, Madrid, Spain
    Vet Dermatol 20:397-404. 2009
    ..Miltefosine, in combination with allopurinol, offers a safe, convenient and effective alternative treatment option for canine leishmaniosis compared to the reference therapy...
  17. ncbi request reprint Relapses versus reinfections in patients coinfected with Leishmania infantum and human immunodeficiency virus type 1
    Miguel A Morales
    World Health Organization Collaborating Centre for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Madrid, Spain
    J Infect Dis 185:1533-7. 2002
    ..These results suggest the utility of this PCR-RFLP analysis in detecting leishmaniasis reinfection in HIV-positive patients...
  18. ncbi request reprint Leishmania/HIV co-infections in the second decade
    Israel Cruz
    WHO Collaborating Centre for Leishmaniasis, National Centre of Microbiology, Institute of Health Carlos III, Madrid, Spain
    Indian J Med Res 123:357-88. 2006
    ..An extensive review of the literature on Leishmania/HIV co-infection has allowed the inclusion of a comprehensive and updated list of bibliographical references...