Rosa Ventura

Summary

Affiliation: Hospital del Mar
Country: Spain

Publications

  1. doi request reprint Detection of the administration of 17beta-nortestosterone in boars by gas chromatography/mass spectrometry
    Rosa Ventura
    Unitat de Recerca en Farmacologia, Institut Municipal d Investigacio Medica, IMIM, Barcelona, Spain
    Rapid Commun Mass Spectrom 22:1863-70. 2008
  2. ncbi request reprint High-throughput and sensitive screening by ultra-performance liquid chromatography tandem mass spectrometry of diuretics and other doping agents
    Rosa Ventura
    Grup de Recerca en Bioanàlisis, IMIM Hospital del Mar, Barcelona, Spain
    Eur J Mass Spectrom (Chichester, Eng) 14:191-200. 2008
  3. doi request reprint Evaluation of the urinary threshold concentration of formoterol in sports drug testing
    Rosa Ventura
    Bioanalysis Research Group, IMIM Hospital del Mar Medical Research Institute, Doctor Aiguader 88, 08003, Barcelona, Spain
    Drug Test Anal 5:266-9. 2013
  4. ncbi request reprint Quantification of perphenazine in eurasian otter (Lutra lutra lutra) urine samples by gas chromatography-mass spectrometry
    R Ventura
    Unitat de Recerca en Farmacologia, Institut Municipal d Investigacio Medica, Barcelona, Spain
    J Chromatogr B Analyt Technol Biomed Life Sci 769:79-87. 2002
  5. doi request reprint Ultraperformance liquid chromatography tandem mass spectrometric method for direct quantification of salbutamol in urine samples in doping control
    R Ventura
    Bioanalysis Research Group, IMIM Hospital del Mar, Barcelona, Spain
    J Pharm Biomed Anal 50:886-90. 2009
  6. ncbi request reprint Stability studies of selected doping agents in urine: caffeine
    R Ventura
    Unitat de Recerca en Farmacologia, Institut Municipal d Investigacio Medica IMIM, Doctor Aiguader 80, 08003 Barcelona, Spain
    J Chromatogr B Analyt Technol Biomed Life Sci 795:167-77. 2003
  7. doi request reprint Immunoassays for the measurement of IGF-II, IGFBP-2 and -3, and ICTP as indirect biomarkers of recombinant human growth hormone misuse in sport. Values in selected population of athletes
    Rosario Abellan
    Bioanalysis and Analytical Services Research Group, Neuropsychopharmacology Program, Institut Municipal d Investigació Mèdica IMIM Hospital del Mar, c Doctor Aiguader 88, 08003 Barcelona, Spain
    J Pharm Biomed Anal 48:844-52. 2008
  8. doi request reprint Evaluation of urinary excretion of androgens conjugated to cysteine in human pregnancy by mass spectrometry
    Andreu Fabregat
    Bioanalysis Research Group, IMIM, Hospital del Mar, Doctor Aiguader 88, 08003 Barcelona, Spain
    J Steroid Biochem Mol Biol 139:192-200. 2014
  9. ncbi request reprint Validation of a procedure for the gas chromatography-mass spectrometry analysis of cocaine and metabolites in pericardial fluid
    Maria Teresa Contreras
    Pharmacology Research Unit, Institut Municipal d Investigacio Medica IMIM, Barcelona, Spain
    J Anal Toxicol 31:75-80. 2007
  10. doi request reprint Urinary metabolic profile of 19-norsteroids in humans: glucuronide and sulphate conjugates after oral administration of 19-nor-4-androstenediol
    Susana Torrado
    Institut Municipal d Investigacio Medica, Barcelona, Spain
    Rapid Commun Mass Spectrom 22:3035-42. 2008

Collaborators

Detail Information

Publications44

  1. doi request reprint Detection of the administration of 17beta-nortestosterone in boars by gas chromatography/mass spectrometry
    Rosa Ventura
    Unitat de Recerca en Farmacologia, Institut Municipal d Investigacio Medica, IMIM, Barcelona, Spain
    Rapid Commun Mass Spectrom 22:1863-70. 2008
    ..According to these results, the detection by GC/MS of some of the 17betaN metabolites described above, different from 17betaN, could be indicative of the exogenous administration of 17betaN to boars...
  2. ncbi request reprint High-throughput and sensitive screening by ultra-performance liquid chromatography tandem mass spectrometry of diuretics and other doping agents
    Rosa Ventura
    Grup de Recerca en Bioanàlisis, IMIM Hospital del Mar, Barcelona, Spain
    Eur J Mass Spectrom (Chichester, Eng) 14:191-200. 2008
    ....
  3. doi request reprint Evaluation of the urinary threshold concentration of formoterol in sports drug testing
    Rosa Ventura
    Bioanalysis Research Group, IMIM Hospital del Mar Medical Research Institute, Doctor Aiguader 88, 08003, Barcelona, Spain
    Drug Test Anal 5:266-9. 2013
    ..mL(-1) is close to nil. For this reason, sports authorities should re-evaluate the need of a threshold concentration for formoterol and its practical usefulness...
  4. ncbi request reprint Quantification of perphenazine in eurasian otter (Lutra lutra lutra) urine samples by gas chromatography-mass spectrometry
    R Ventura
    Unitat de Recerca en Farmacologia, Institut Municipal d Investigacio Medica, Barcelona, Spain
    J Chromatogr B Analyt Technol Biomed Life Sci 769:79-87. 2002
    ..3 to 14.9% and accuracy from 3.1 to 11.8%. Examples of the application of the perphenazine quantification method in otter urines after administration of perphenazine enanthate are presented...
  5. doi request reprint Ultraperformance liquid chromatography tandem mass spectrometric method for direct quantification of salbutamol in urine samples in doping control
    R Ventura
    Bioanalysis Research Group, IMIM Hospital del Mar, Barcelona, Spain
    J Pharm Biomed Anal 50:886-90. 2009
    ..9%. The method was shown to be reliable when applying to routine samples, and the short analysis time resulting from a simple sample preparation and a fast instrumental analysis makes it of great interest for antidoping control purposes...
  6. ncbi request reprint Stability studies of selected doping agents in urine: caffeine
    R Ventura
    Unitat de Recerca en Farmacologia, Institut Municipal d Investigacio Medica IMIM, Doctor Aiguader 80, 08003 Barcelona, Spain
    J Chromatogr B Analyt Technol Biomed Life Sci 795:167-77. 2003
    ..The stability of caffeine was also evaluated in non-sterile samples stored at -20 degrees C for 18 months. No significant loss of the compound was observed at any of the investigated conditions...
  7. doi request reprint Immunoassays for the measurement of IGF-II, IGFBP-2 and -3, and ICTP as indirect biomarkers of recombinant human growth hormone misuse in sport. Values in selected population of athletes
    Rosario Abellan
    Bioanalysis and Analytical Services Research Group, Neuropsychopharmacology Program, Institut Municipal d Investigació Mèdica IMIM Hospital del Mar, c Doctor Aiguader 88, 08003 Barcelona, Spain
    J Pharm Biomed Anal 48:844-52. 2008
    ..Variations due to those aspects should be taken in careful consideration in the hypothesis of setting reference concentration ranges for doping detection...
  8. doi request reprint Evaluation of urinary excretion of androgens conjugated to cysteine in human pregnancy by mass spectrometry
    Andreu Fabregat
    Bioanalysis Research Group, IMIM, Hospital del Mar, Doctor Aiguader 88, 08003 Barcelona, Spain
    J Steroid Biochem Mol Biol 139:192-200. 2014
    ..These alterations have to be taken into consideration if anabolic steroids are included into the Athlete Biological Passport. This article is part of a Special Issue entitled 'Pregnancy and Steroids'. ..
  9. ncbi request reprint Validation of a procedure for the gas chromatography-mass spectrometry analysis of cocaine and metabolites in pericardial fluid
    Maria Teresa Contreras
    Pharmacology Research Unit, Institut Municipal d Investigacio Medica IMIM, Barcelona, Spain
    J Anal Toxicol 31:75-80. 2007
    ..In this study, the procedure has been successfully applied to a number of forensic cases involving cocaine intoxication...
  10. doi request reprint Urinary metabolic profile of 19-norsteroids in humans: glucuronide and sulphate conjugates after oral administration of 19-nor-4-androstenediol
    Susana Torrado
    Institut Municipal d Investigacio Medica, Barcelona, Spain
    Rapid Commun Mass Spectrom 22:3035-42. 2008
    ..Our results suggest that sulphate metabolites should be taken into consideration in order to increase the retrospectivity in the detection of 19-norsteroids after oral administration...
  11. doi request reprint Evaluation of immunoassays for the measurement of insulin and C-peptide as indirect biomarkers of insulin misuse in sport: values in selected population of athletes
    Rosario Abellan
    Bioanalysis and Analytical Services Research Group, Neuropsychopharmacology Program, Institut Municipal d Investigació Mèdica IMIM Hospital del Mar, c Doctor Aiguader 88, 08003 Barcelona, Spain
    J Pharm Biomed Anal 49:793-9. 2009
    ..Variations due to those aspects should be taken in careful consideration in the hypothesis of setting reference concentration ranges for doping detection...
  12. doi request reprint Discrimination of prohibited oral use from authorized inhaled treatment of budesonide in sports
    Xavier Matabosch
    Bioanalysis Research Group, Institut Hospital del Mar d Investigacions Mèdiques IMIM, Barcelona, Spain
    Ther Drug Monit 35:118-28. 2013
    ....
  13. doi request reprint Stability of drugs of abuse in oral fluid collection devices with purpose of external quality assessment schemes
    Montse Ventura
    Grup de Recerca en Bioanàlisis i Serveis Analítics, Programa de Recerca en Neuropsicofarmacologia, Institut Municipal d Investigació Mèdica Hospital del Mar, Universitat Autonoma de Barcelona, Barcelona, Spain
    Ther Drug Monit 31:277-80. 2009
    ....
  14. ncbi request reprint Evaluation of immunoassays for the measurement of insulin-like growth factor-I and procollagen type III peptide, indirect biomarkers of recombinant human growth hormone misuse in sport
    Rosario Abellan
    Unitat de Recerca en Farmacologia, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Clin Chem Lab Med 43:75-85. 2005
    ..However, the validation studies carried out show the need for harmonization of immunoassay parameters to improve the reproducibility and comparability of results between different laboratories and in different studies...
  15. doi request reprint Urinary profile of methylprednisolone and its metabolites after oral and topical administrations
    Xavier Matabosch
    Bioanalysis Research Group, IMIM Institut Hospital del Mar d Investigacions Mèdiques, Doctor Aiguader 88, 08003 Barcelona, Spain Electronic address
    J Steroid Biochem Mol Biol 138:214-21. 2013
    ..Their signals after topical administration were lower than those obtained in the first 48h after all oral doses. ..
  16. doi request reprint Alternative markers for the long-term detection of oral testosterone misuse
    Andreu Fabregat
    Bioanalysis Research Group, IMIM, Hospital del Mar, Doctor Aiguader 88, 08003 Barcelona, Spain
    Steroids 76:1367-76. 2011
    ..Moreover, several ratios between these compounds were evaluated. Some of them improved the detection of testosterone misuse when comparing with T/E. The best results were obtained with those ratios involving androsta-1,4-dien-3,17-dione...
  17. doi request reprint Detection of dihydrotestosterone gel, oral dehydroepiandrosterone, and testosterone gel misuse through the quantification of testosterone metabolites released after alkaline treatment
    Andreu Fabregat
    Bioanalysis Research Group, IMIM, Hospital del Mar, Doctor Aiguader 88, 08003 Barcelona, Spain
    Drug Test Anal 3:828-35. 2011
    ..When using basic released metabolites, shorter DTs were obtained for DHT, similar DTs for DHEA, and the detectability was substantially improved for T gel...
  18. doi request reprint Current strategic approaches for the detection of blood doping practices
    Jordi Segura
    Bioanalysis Research Group, IMIM Hospital del Mar Research Institute, Barcelona, Spain
    Forensic Sci Int 213:42-8. 2011
    ....
  19. doi request reprint Growth hormone in sport: beyond Beijing 2008
    Jordi Segura
    Bioanalysis and Analytical Services Research Group, Institut Municipal d Investigació Mèdica IMIM Hospital del Mar, Universitat Pompeu Fabra, Barcelona, Spain
    Ther Drug Monit 31:3-13. 2009
    ..In parallel with the new types of abuse, which will surely emerge in the near future, the research and development for the improvement of the analytical detection of GH itself will continue...
  20. doi request reprint Identification of budesonide metabolites in human urine after oral administration
    Xavier Matabosch
    Bioanalysis Research Group, IMIM, Institut de Recerca Hospital del Mar, Doctor Aiguader 88, 08003, Barcelona, Spain
    Anal Bioanal Chem 404:325-40. 2012
    ..Metabolites were mainly excreted in the free fraction. All of them were excreted in urine during the first 24 h after administration, and seven of them were still detected up to 48 h after administration for both volunteers...
  21. doi request reprint Plasticizers excreted in urine: indication of autologous blood transfusion in sports
    Núria Monfort
    Bioanalysis Research Group, IMIM Hospital del Mar Research Institute, the Universitat Pompeu Fabra, Barcelona, Spain
    Transfusion 52:647-57. 2012
    ..This study evaluates DEHP metabolites in urine for detecting autologous blood transfusion...
  22. ncbi request reprint Quantitation of 17beta-nandrolone metabolites in boar and horse urine by gas chromatography-mass spectrometry
    Meritxell Roig
    Unitat de Recerca en Farmacologia, Institut Municipal d Investigacuó Mèdica, Dr Aiguader, 80, 08003 Barcelona, Spain
    Anal Chim Acta 586:184-95. 2007
    ..The method was applied to the analysis of urine samples collected after administration of 17betaN laureate to boars and horses, and its suitability for the quantitation of the metabolites in the three fractions has been demonstrated...
  23. ncbi request reprint Stability studies of principal illicit drugs in oral fluid: preparation of reference materials for external quality assessment schemes
    Montserrat Ventura
    Unitat de Recerca en Farmacologia, Institut Municipal d Investigacio Medica, Spain
    Ther Drug Monit 29:662-5. 2007
    ....
  24. ncbi request reprint Adrenal hormonal imbalance in acute intermittent porphyria patients: results of a case control study
    Oscar J Pozo
    Bioanalysis Research Group, IMIM, Hospital del Mar Medical Research Institute, Doctor Aiguader 88, Barcelona 08003, Spain
    Orphanet J Rare Dis 9:54. 2014
    ..To asses the hypothesis that steroidogenesis may be modified in AIP patients with biochemically active disease, we undertook a comprehensive analysis of the urinary steroid metabolome...
  25. doi request reprint Use of LC-MS/MS for the open detection of steroid metabolites conjugated with glucuronic acid
    Andreu Fabregat
    Bioanalysis Research Group, IMIM, Hospital del Mar, Barcelona, Spain
    Anal Chem 85:5005-14. 2013
    ..Moreover, these results exemplify that significant information might be missed, unless direct methods for the determination of steroid glucuronides are employed...
  26. ncbi request reprint Detection, synthesis and characterization of metabolites of steroid hormones conjugated with cysteine
    Andreu Fabregat
    Bioanalysis Research Group, IMIM, Hospital del Mar, Doctor Aiguader 88, 08003 Barcelona, Spain
    Steroids 78:327-36. 2013
    ....
  27. doi request reprint Gas chromatography-mass spectrometry method for the analysis of 19-nor-4-androstenediol and metabolites in human plasma: application to pharmacokinetic studies after oral administration of a prohormone supplement
    Susana Torrado
    Institut Municipal d Investigacio Medica, IMIM, Dr Aiguader 88, 08003 Barcelona, Spain
    Steroids 73:751-9. 2008
    ..Nandrolone, norandrostenedione and 19-nor-4-androstenediol were also detected at lower concentrations...
  28. doi request reprint Determination of five di-(2-ethylhexyl)phthalate metabolites in urine by UPLC-MS/MS, markers of blood transfusion misuse in sports
    Núria Monfort
    Grup de Recerca en Bioanàlisi i Serveis Analítics, Programa de Recerca en Neurociències, Institut Hospital del Mar d Investigacions Mèdiques, Barcelona, Spain
    J Chromatogr B Analyt Technol Biomed Life Sci 908:113-21. 2012
    ..Additionally, threshold concentrations indicating outliers of common exposure for DEHP metabolites are proposed...
  29. doi request reprint Recent developments in MS for small molecules: application to human doping control analysis
    Oscar J Pozo
    Bioanalysis Research Group, IMIM, Hospital del Mar, Doctor Aiguader 88, 08003 Barcelona, Spain
    Bioanalysis 4:197-212. 2012
    ..Finally, a brief discussion about trends and remaining limitations is presented...
  30. doi request reprint Quantification of testosterone and metabolites released after alkaline treatment in human urine
    Andreu Fabregat
    Bioanalysis Research Group, IMIM, Hospital del Mar, Doctor Aiguader 88, Barcelona, Spain
    Drug Test Anal 2:630-6. 2010
    ..Short analysis time, simple sample preparation, and satisfactory quantitative parameters make this method potentially useful for anti-doping control purposes...
  31. ncbi request reprint Intermittent hypoxia exposure in a hypobaric chamber and erythropoietin abuse interpretation
    Rosario Abellan
    Pharmacology Research Unit, Institut Municipal d Investigacio Medica, IMIM UPF, Barcelona, Spain
    J Sports Sci 25:1241-50. 2007
    ....
  32. doi request reprint Bioanalysis and Analytical Services Research Group at The Municipal Institute for Medical Research IMIM-Hospital del Mar, Spain
    Jordi Segura
    Municipal Institute for Medical Research IMIM Hospital del Mar, Pompeu Fabra University, Biomedical Research Park, Barcelona, Spain
    Bioanalysis 1:1403-9. 2009
    ..The experiences reported in this article will be of general interest, especially for analysts studying the determination of substances in biological material...
  33. doi request reprint Current status and bioanalytical challenges in the detection of unknown anabolic androgenic steroids in doping control analysis
    Oscar J Pozo
    Bioanalysis Research Group, IMIM, Hospital del Mar, Doctor Aiguader 88, 08003 Barcelona, Spain
    Bioanalysis 5:2661-77. 2013
    ..Although important steps have been made in order to minimize this analytical problem and different analytical strategies have been proposed, there are still some drawbacks related to each approach. ..
  34. ncbi request reprint Application of pericardial fluid to the analysis of morphine (heroin) and cocaine in forensic toxicology
    Maria Teresa Contreras
    National Institute of Toxicology, Department of Barcelona, Barcelona, Spain
    Forensic Sci Int 164:168-71. 2006
    ..In spite of that, it raises the possibility of using the immunoassay as a preliminary technique in forensic toxicology...
  35. doi request reprint Alterations of the erythrocyte membrane proteome and cytoskeleton network during storage--a possible tool to identify autologous blood transfusion
    Zoran Nikolovski
    Bioanalysis Research Group, IMIM Hospital del Mar Research Institute, Barcelona, Spain
    Drug Test Anal 4:882-90. 2012
    ..They are mostly located in cytoskeleton--spectrin β, band 4.2, ankyrin-1, tropomodulin-1, β adducin, band 4.9 (dematin), tropomyosin, while some changes were also observed in transmembrane proteins (glycophorin C, aquaporin-1, band 3)...
  36. doi request reprint Progress in the removal of di-[2-ethylhexyl]-phthalate as plasticizer in blood bags
    Juliane Simmchen
    Bioanalysis and Analytical Services Research Group, IMIM Hospital del Mar Research Institute, Pompeu Fabra University, Barcelona, Spain
    Transfus Med Rev 26:27-37. 2012
    ..Different strategies as well as the most promising approaches are presented in this review. In any case, the degree of stabilization of RBCs undergoing prolonged storage will dictate the final acceptance for such alternatives...
  37. doi request reprint Investigation of endogenous corticosteroids profiles in human urine based on liquid chromatography tandem mass spectrometry
    Josep Marcos
    Bioanalysis Research Group, IMIM, Hospital del Mar Medical Research Institute, Doctor Aiguader 88, 08003 Barcelona, Spain Department of Experimental and Health Sciencies, Universitat Pompeu Fabra, Doctor Aiguader 88, 08003 Barcelona, Spain
    Anal Chim Acta 812:92-104. 2014
    ..The wide coverage of corticosteroid metabolism, together with short analysis time, low sample volume, simple sample preparation, and satisfactory quantitative results make this method useful for clinical purposes...
  38. doi request reprint Using complementary mass spectrometric approaches for the determination of methylprednisolone metabolites in human urine
    Oscar J Pozo
    Bioanalysis Research Group, IMIM, Institut de Recerca Hospital del Mar, Doctor Aiguader 88, 08003, Barcelona, Spain
    Rapid Commun Mass Spectrom 26:541-53. 2012
    ..Recently developed liquid chromatography/tandem mass spectrometry (LC/MS/MS) strategies for the detection of corticosteroid metabolites have been applied to the study of methylprednisolone metabolism...
  39. ncbi request reprint Evaluation of immunoassays for the measurement of erythropoietin (EPO) as an indirect biomarker of recombinant human EPO misuse in sport
    Rosario Abellan
    Unitat de Recerca en Farmacologia, Institut Municipal d Investigacio Medica, c Doctor Aiguader 80, 08003 Barcelona, Spain
    J Pharm Biomed Anal 35:1169-77. 2004
    ..Better inter-laboratory results were obtained with the CHEM assay and, hence, it is considered the recommended assay for anti-doping control analysis...
  40. doi request reprint Urinary di-(2-ethylhexyl)phthalate metabolites in athletes as screening measure for illicit blood doping: a comparison study with patients receiving blood transfusion
    Núria Monfort
    Bioanalysis Research Group, IMIM Hospital del Mar, Barcelona, Spain
    Transfusion 50:145-9. 2010
    ..Exposure to DEHP has been evaluated by measuring DEHP metabolites in selected groups of subjects...
  41. doi request reprint Testosterone metabolism revisited: discovery of new metabolites
    Oscar J Pozo
    Bioanalysis Research Group, IMIM, Hospital del Mar, Doctor Aiguader 88, 08003 Barcelona, Spain
    Anal Bioanal Chem 398:1759-70. 2010
    ..Both compounds were also detected after KOH treatment, suggesting that this metabolic pathway is involved in the endogenous detection of boldenone previously reported by several authors...
  42. ncbi request reprint Diagnostic evidence for the presence of beta-agonists using two consecutive derivatization procedures and gas chromatography-mass spectrometric analysis
    Lúcia Damasceno
    Unitat de Farmacologia, Institut Municipal d Investigacio Medica, Barcelona, Spain
    J Chromatogr B Analyt Technol Biomed Life Sci 780:61-71. 2002
    ..5 to 5 ng/ml. This procedure was tested with the beta-agonists bambuterol, clenbuterol, fenoterol, formoterol, salbutamol, salmeterol, alpha-hydroxy-salmeterol and terbutaline...
  43. doi request reprint Pharmacokinetics of buprenorphine after intravenous administration of clinical doses to dogs
    Anna Andaluz
    Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Autonomous University of Barcelona U A B, 08193 Bellaterra, Barcelona, Spain
    Vet J 181:299-304. 2009
    ..The relationship between plasma concentrations and dynamic effects in dogs remains to be established...
  44. doi request reprint Clarification on the detection of epoetin delta and epoetin omega using isoelectric focusing
    Viviana Belalcazar
    Am J Hematol 83:754; author reply 754-5. 2008